Proteasome-dependent processing of topoisomerase I-DNA adducts into DNA double strand breaks at arrested replication forks

Journal of Biological Chemistry

Volumn 284, Issue 41, 2009, Pages 28084-28092

  Lin, Chao Po ^a   Ban, Yi ^a   Lyu, Yi Lisa ^a   Liu, Leroy F ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATAXIA-TELANGIECTASIA MUTATED; CAMPTOTHECINS; COLLISION MODEL; COMET ASSAYS; COMPLEX SITES; DNA ADDUCTS; DNA CLEAVAGE; DNA DAMAGES; DNA DOUBLE STRAND BREAKS; DNA LESIONS; HYDROXYUREA; IMMUNOCYTOCHEMICAL STUDY; IRINOTECAN; POLYUBIQUITIN; PROTEASOME INHIBITORS; PROTEASOMES; REPLICATION FORK; TOPOISOMERASE I; TOPOTECAN; UBIQUITIN; UBIQUITIN LIGASES;

CHARGE TRAPPING; DNA; ENZYMES; GENES; IONIZING RADIATION; PHOSPHORYLATION; PROTEINS; RUNOFF;

NUCLEIC ACIDS;

ATM PROTEIN; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CAMPTOTHECIN; CHECKPOINT KINASE 2; DNA TOPOISOMERASE; HISTONE H2AX; HYDROXYUREA; PROTEASOME; UBIQUITIN ACTIVATING ENZYME E1; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ARTICLE; COMET ASSAY; CONTROLLED STUDY; DNA ADDUCT; DNA DEGRADATION; DNA PROTEIN COMPLEX; DNA REPLICATION; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IONIZING RADIATION; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION;

APHIDICOLIN; DNA; DNA ADDUCTS; DNA BREAKS, DOUBLE-STRANDED; DNA REPLICATION; DNA TOPOISOMERASES, TYPE I; ENZYME INHIBITORS; HELA CELLS; HISTONES; HUMANS; LEUPEPTINS; MOLECULAR CHAPERONES; PROTEASOME ENDOPEPTIDASE COMPLEX; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; UBIQUITIN;

ATAXIA TELANGIECTASIA;

EID: 70350502118     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.030601     Document Type: Article

References (50)

1. Wang, J. C. (1996) Annu. Rev. Biochem. 65, 635-692
2. Wang, J. C. (2002) Nat. Rev. Mol. Cell Biol. 3, 430-440
3. Li, T. K., and Liu, L. F. (2001) Annu. Rev. Pharmacol. Toxicol. 41, 53-77
4. Champoux, J. J. (2001) Annu. Rev. Biochem. 70, 369-413
5. Pommier, Y. (2006) Nat. Rev. Cancer 6, 789-802
6. Hsiang, Y. H., Hertzberg, R., Hecht, S., and Liu, L. F. (1985) J. Biol. Chem. 260, 14873-14878
7. Hsiang, Y. H., and Liu, L. F. (1988) Cancer Res. 48, 1722-1726
8. Desai, S. D., Zhang, H., Rodriguez-Bauman, A., Yang, J. M., Wu, X., Gounder, M. K., Rubin, E. H., and Liu, L. F. (2003) Mol. Cell. Biol. 23, 2341-2350
9. Hsiang, Y. H., Lihou, M. G., and Liu, L. F. (1989) Cancer Res. 49, 5077-5082
10. Strumberg, D., Pilon, A. A., Smith, M., Hickey, R., Malkas, L., and Pommier, Y. (2000) Mol. Cell. Biol. 20, 3977-3987
11. Tsao, Y. P., Russo, A., Nyamuswa, G., Silber, R., and Liu, L. F. (1993) Cancer Res. 53, 5908-5914
12. D'Arpa, P., Beardmore, C., and Liu, L. F. (1990) Cancer Res. 50, 6919-6924
13. Holm, C., Covey, J. M., Kerrigan, D., and Pommier, Y. (1989) Cancer Res. 49, 6365-6368
14. Nitiss, J. L., and Wang, J. C. (1996) Mol. Pharmacol. 50, 1095-1102
15. Reid, R. J., Fiorani, P., Sugawara, M., and Bjornsti, M. A. (1999) Proc. Natl. Acad. Sci. U.S.A. 96, 11440-11445
16. Zhang, H., D'Arpa, P., and Liu, L. F. (1990) Cancer Cells 2, 23-27
17. Desai, S. D., Liu, L. F., Vazquez-Abad, D., and D'Arpa, P. (1997) J. Biol. Chem. 272, 24159-24164
18. Desai, S. D., Wood, L. M., Tsai, Y. C., Hsieh, T. S., Marks, J. R., Scott, G. L., Giovanella, B. C., and Liu, L. F. (2008) Mol. Cancer Ther. 7, 1430-1439
19. Lyu, Y. L., Kerrigan, J. E., Lin, C. P., Azarova, A. M., Tsai, Y. C., Ban, Y., and Liu, L. F. (2007) Cancer Res. 67, 8839-8846
20. Mao, Y., Desai, S. D., Ting, C. Y., Hwang, J., and Liu, L. F. (2001) J. Biol. Chem. 276, 40652-40658
21. Desai, S. D., Li, T. K., Rodriguez-Bauman, A., Rubin, E. H., and Liu, L. F. (2001) Cancer Res. 61, 5926-5932
22. Seiler, J. A., Conti, C., Syed, A., Aladjem, M. I., and Pommier, Y. (2007) Mol. Cell. Biol. 27, 5806-5818
23. Lin, C. P., Ban, Y., Lyu, Y. L., Desai, S. D., and Liu, L. F. (2008) J. Biol. Chem. 283, 21074-21083
24. Thiriet, C., and Hayes, J. J. (2005) Mol. Cell 18, 617-622
25. Shao, R. G., Cao, C. X., Zhang, H., Kohn, K. W., Wold, M. S., and Pommier, Y. (1999) EMBO J. 18, 1397-1406
26. Takemura, H., Ashutosh Rao, V., Sordet, O., Furuta, T., Miao, Z. H., Meng, L., Zhang, H., and Pommier, Y. (2006) J. Biol. Chem. 281, 30814-30823
27. Zhang, Y. W., Otterness, D. M., Chiang, G. G., Xie, W., Liu, Y. C., Mercurio, F., and Abraham, R. T. (2005) Mol. Cell 19, 607-618
28. Hoyt, M. A., and Coffino, P. (2004) Cell. Mol. Life Sci. 61, 1596-1600
29. Aleo, E., Henderson, C. J., Fontanini, A., Solazzo, B., and Brancolini, C. (2006) Cancer Res. 66, 9235-9244
30. Finley, D., Ciechanover, A., and Varshavsky, A. (1984) Cell 37, 43-55
31. Zhang, H. F., Tomida, A., Koshimizu, R., Ogiso, Y., Lei, S., and Tsuruo, T. (2004) Cancer Res. 64, 1114-1121
32. Fricke, B., Heink, S., Steffen, J., Kloetzel, P. M., and Krüger, E. (2007) EMBO Rep. 8, 1170-1175
33. Pickart, C. M. (2001) Annu. Rev. Biochem. 70, 503-533
34. Ikeda, F., and Dikic, I. (2008) EMBO Rep. 9, 536-542
35. Desai, S. D., Haas, A. L., Wood, L. M., Tsai, Y. C., Pestka, S., Rubin, E. H., Saleem, A., Nur-E-Kamal, A., and Liu, L. F. (2006) Cancer Res. 66, 921-928
36. Andersen, J. B., Aaboe, M., Borden, E. C., Goloubeva, O. G., Hassel, B. A., and Orntoft, T. F. (2006) Br. J. Cancer 94, 1465-1471
37. Kiessling, A., Hogrefe, C., Erb, S., Bobach, C., Fuessel, S., Wessjohann, L., and Seliger, B. (2009) Oncogene 28, 2606-2620
38. Pommier, Y., Barcelo, J. M., Rao, V. A., Sordet, O., Jobson, A. G., Thibaut, L., Miao, Z. H., Seiler, J. A., Zhang, H., Marchand, C., Agama, K., Nitiss, J. L., and Redon, C. (2006) Prog. Nucleic Acids Res. Mol. Biol. 81, 179-229
39. Debéthune, L., Kohlhagen, G., Grandas, A., and Pommier, Y. (2002) Nucleic Acids Res. 30, 1198-1204
40. Interthal, H., Chen, H. J., and Champoux, J. J. (2005) J. Biol. Chem. 280, 36518-36528
41. Yang, S. W., Burgin, A. B., Jr., Huizenga, B. N., Robertson, C. A., Yao, K. C., and Nash, H. A. (1996) Proc. Natl. Acad. Sci. U.S.A. 93, 11534-11539
42. Moreau, S., Ferguson, J. R., and Symington, L. S. (1999) Mol. Cell. Biol. 19, 556-566
43. Krogan, N. J., Lam, M. H., Fillingham, J., Keogh, M. C., Gebbia, M., Li, J., Datta, N., Cagney, G., Buratowski, S., Emili, A., and Greenblatt, J. F. (2004) Mol. Cell 16, 1027-1034
44. Gudmundsdottir, K., Lord, C. J., and Ashworth, A. (2007) Oncogene 26, 7601-7606
45. Mateos, M. V., Hernaéndez, J. M., Hernaéndez, M. T., Gutiérrez, N. C., Palomera, L., Fuertes, M., Díaz-Mediavilla, J., Lahuerta, J. J., de la Rubia, J., Terol, M. J., Sureda, A., Bargay, J., Ribas, P., de Arriba, F., Alegre, A., Oriol, A., Carrera, D., García-Larana, J., García-Sanz, R., Bladé, J., Prósper, F., Mateo, G., Esseltine, D. L., van de Velde, H., and San Miguel, J. F. (2006) Blood 108, 2165-2172
46. Mimnaugh, E. G., Yunmbam, M. K., Li, Q., Bonvini, P., Hwang, S. G., Trepel, J., Reed, E., and Neckers, L. (2000) Biochem. Pharmacol. 60, 1343-1354
47. Mitsiades, N., Mitsiades, C. S., Richardson, P. G., Poulaki, V., Tai, Y. T., Chauhan, D., Fanourakis, G., Gu, X., Bailey, C., Joseph, M., Libermann, T. A., Schlossman, R., Munshi, N. C., Hideshima, T., and Anderson, K. C. (2003) Blood 101, 2377-2380
48. Pajonk, F., van Ophoven, A., Weissenberger, C., and McBride, W. H. (2005) BMC Cancer 5, 76
49. Murakawa, Y., Sonoda, E., Barber, L. J., Zeng, W., Yokomori, K., Kimura, H., Niimi, A., Lehmann, A., Zhao, G. Y., Hochegger, H., Boulton, S. J., and Takeda, S. (2007) Cancer Res. 67, 8536-8543
50. Furuta, T., Takemura, H., Liao, Z. Y., Aune, G. J., Redon, C., Sedelnikova, O. A., Pilch, D. R., Rogakou, E. P., Celeste, A., Chen, H. T., Nussenzweig, A., Aladjem, M. I., Bonner, W. M., and Pommier, Y. (2003) J. Biol. Chem. 278, 20303-20312