Cellular and molecular neuropathology of the cuprizone mouse model: Clinical relevance for multiple sclerosis

Neuroscience and Biobehavioral Reviews

Volumn 47, Issue , 2014, Pages 485-505

  Praet, Jelle ^a   Guglielmetti, Caroline ^a   Berneman, Zwi ^a   Van der Linden, Annemie ^a   Ponsaerts, Peter ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

Cuprizone; Demyelination; Epilepsy; Metabolic stress; Multiple sclerosis; Myelin; Neuroinflammation; Oligodendrocyte; Remyelination; Schizophrenia

Indexed keywords

ALPHA INTERFERON RECEPTOR; BETA INTERFERON RECEPTOR; CASPASE 3; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CXCR2; CUPRIZONE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FIBROBLAST GROWTH FACTOR 2; GAMMA INTERFERON; GLIAL FIBRILLARY ACIDIC PROTEIN; I KAPPA B KINASE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; INTERLEUKIN 17; INTERLEUKIN 17 RECEPTOR; INTERLEUKIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; MYELIN; NEUROTROPHIC FACTOR; NOTCH1 RECEPTOR; PHOSPHOLIPASE A2; PROSTACYCLIN; PROSTAGLANDIN E2; PROSTAGLANDIN H2; SUPPRESSOR OF CYTOKINE SIGNALING 3; THROMBOXANE A2; TUMOR NECROSIS FACTOR ALPHA RECEPTOR;

ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ASTROCYTOSIS; CONTROLLED STUDY; DEMYELINATION; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ENZYME INHIBITION; EPILEPSY; IMMUNE SYSTEM; MACROPHAGE; METABOLIC STRESS; MITOCHONDRION; MOUSE; MULTIPLE SCLEROSIS; MYELIN SHEATH; NERVOUS SYSTEM INFLAMMATION; NEUROPATHOLOGY; NEUROTRANSMISSION; NEUTROPHIL; NONHUMAN; OLIGODENDROGLIA; OXIDATIVE STRESS; PERIKARYON; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; REMYELINIZATION; REVIEW; SCHIZOPHRENIA; ANIMAL; BRAIN; CHEMICALLY INDUCED; DISEASE MODEL; GLIA; METABOLISM; NERVE CELL; PATHOLOGY; PHYSIOLOGY;

ANIMALS; BRAIN; CUPRIZONE; DISEASE MODELS, ANIMAL; MICE; MULTIPLE SCLEROSIS; MYELIN SHEATH; NEUROGLIA; NEURONS; OXIDATIVE STRESS;

EID: 84908670613     PISSN: 01497634     EISSN: 18737528     Source Type: Journal    
DOI: 10.1016/j.neubiorev.2014.10.004     Document Type: Review

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