Adult CNP::EGFP transgenic mouse shows pronounced hypomyelination and an increased vulnerability to cuprizone-induced demyelination

Experimental Neurology

Volumn 233, Issue 1, 2012, Pages 490-504

  Millet, V ^a   Marder, M ^a   Pasquini, L A ^a  

^a Instituto de Quimica y Fisicoquimica Biologicas Buenos Aires   (Argentina)

Author keywords

Astroglial response; CNP::EGFP mice; Cuprizone; Demyelination; Hypomyelination; Microglial activation; Myelination; Oligodendrocytes

Indexed keywords

2',3' CYCLIC NUCLEOTIDE 3' PHOSPHODIESTERASE; CELL MARKER; ENHANCED GREEN FLUORESCENT PROTEIN; INTERLEUKIN 1BETA; MALTOSE BINDING PROTEIN; MYELIN PROTEIN; NESTIN; NEURON SPECIFIC NUCLEAR PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; CELL ACTIVATION; CELL COUNT; CELL ENLARGEMENT; CELL LOSS; CELL MATURATION; CELL SIZE; CELL STRUCTURE; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; CORPUS CALLOSUM; DEMYELINATION; ELECTRON MICROSCOPY; ENZYME DEFICIENCY; EXPLORATORY BEHAVIOR; HIPPOCAMPAL CA3 REGION; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LAMELLAR BODY; LIPID PEROXIDATION; LOCOMOTION; MICROGLIA; MITOCHONDRION; MORPHOMETRICS; MOTOR DYSFUNCTION; MOUSE; MYELINATED NERVE; NONHUMAN; OLIGODENDROGLIA; OPTIC NERVE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL; TRANSGENIC MOUSE;

2',3'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASES; ALDEHYDES; ANIMALS; ANTIGENS, CD11B; BRAIN; CUPRIZONE; DEMYELINATING DISEASES; DISEASE MODELS, ANIMAL; ECTODYSPLASINS; EXPLORATORY BEHAVIOR; GENE EXPRESSION REGULATION; GREEN FLUORESCENT PROTEINS; INTERLEUKIN-1BETA; MALE; MAZE LEARNING; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA; MONOAMINE OXIDASE INHIBITORS; MOTOR ACTIVITY; MYELIN PROTEINS; NERVE TISSUE PROTEINS; OLIGODENDROGLIA; PSYCHOMOTOR PERFORMANCE; REACTIVE OXYGEN SPECIES; STEM CELLS; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84856228565     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2011.11.028     Document Type: Article

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