Inhibition of the proteasome by lactacystin enhances oligodendroglial cell differentiation

Journal of Neuroscience

Volumn 23, Issue 11, 2003, Pages 4635-4644

  Pasquini, Laura A ^a   Paez, Pablo M ^a   Besio Moreno, Marcos A N ^a   Pasquini, Juana M ^a   Soto, Eduardo F ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Cyclins; Differentiation; JAK STAT; Lactacystin; MG132; Myelination; Oligodendroglial cells; p27kip1; Proteasome; Ubiquitin

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; BROXURIDINE; CYCLIN D; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN E; LACTACYSTIN; MYELIN BASIC PROTEIN; PROTEASOME; PROTEIN P27; PROTEOLIPID PROTEIN; STAT1 PROTEIN; STAT3 PROTEIN; STAT5 PROTEIN; UBIQUITIN;

ANIMAL CELL; ARTICLE; CELL CYCLE; CELL MATURATION; CELL PROLIFERATION; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; IMMUNOCYTOCHEMISTRY; MYELINATION; NERVE CELL DIFFERENTIATION; NEWBORN; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RAT;

EID: 0037866388     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-11-04635.2003     Document Type: Article

References (39)

1. Akaishi T, Shiomi T, Sawada H, Yokosawa H (1996) Purification and properties of 26S proteasome from the rat brain: evidence for its degradation of myelin basic protein in a ubiquitin-dependent manner. Brain Res 722:139-144.
2. Bansal R, Stefanson K, Pfeiffer SE (1992) Proligodendroblast antigen (POA), a developmental antigen expressed by A007/O4-positive oligodendrocyte progenitors prior to the appearance of sulfatide and galatocerebroside. J Neurochem 58:2221-2229.
3. Beyette J, Mason GG, Murray RZ, Cohen GM, Rivett AJ (1998) Proteasome activities decrease during dexamethasone-induced apoptosis of thymocytes. Biochem J 332:315-320.
4. Bonfanti L, Candeo P, Piccinini M, Carmignoto G, Comelli MC, Ghidella S, Bruno R, Gobetto A, Merighi A (1992) Distribution of protein gene product 9.5 (PGP 9.5) in the vertebrate retina: evidence that immunoreactivity is restricted to mammalian horizontal and ganglion cells. J Comp Neurol 322:35-44.
5. Casaccia-Bonnefil P, Aibel L, Chao MV (1996) Central glia and neuronal populations display differential sensitivity to ceramide-dependent cell death. J Neurosci Res 43:382-389.
6. kip1. Genes Dev 11:2335-2346.
7. Dell'Albani P, Kahn MA, Cole R, Condorelli DF, Giuffrida-Stella AM, de Vellis J (1998) Oligodendroglial survival factors PDGF-AA and CNTF activate similar JAK/STAT signaling pathways. J Neurosci Res 54:191-205.
8. Diehl JA, Zindy F, Sherr CJ (1997) Inhibition of cyclin D1 phosphorylation on threonine 286 prevents its rapid degradation via the ubiquitin-proteasome pathway. Genes Dev 11:957-972.
9. Fahrbach SE, Schwartz LM (1994) Localization of immunoreactive ubiquitin in the nervous system of the Manduca sexta moth. J Comp Neurol 343:464-482.
10. Fenteany G, Schreiber SL (1998) Lactacystin, proteasome function, and cell fate. J Biol Chem 273:8545-8548.
11. Fenteany G, Standaert RF, Lane WS, Choi S, Corey EJ, Schreiber SL (1995) Inhibition of proteasome activities and subunit specific-amino terminal threonine modification by lactacystin. Science 268:726-731.
12. Flann S, Hawkes RB, Riederer BM, Rider CC, Beesley PW (1997) Changes in ubiquitin immunoreactivity in developing rat brain: a putative role for ubiquitin and ubiquitin conjugates in dendritic outgrowth and differentiation. Neuroscience 81:173-187.
13. Gorospe M, Liu Y, Xu Q, Chrest FJ, Holbrook NJ (1996) Inhibition of G1 cyclin-dependent kinase activity during growth arrest of human breast carcinoma cells by prostaglandin A2. Mol Cell Biol 16:762-770.
14. Huang Z, Tang XM, Cambi F (2002) Down-regulation of the retinoblastoma protein (Rb) is associated with rat oligodendrocyte differentiation. Mol Cell Neurosci 19:250-262.
15. Kim TK, Maniatis T (1996) Regulation of interferon-γ-activated STAT1 by the ubiquitin-proteasome pathway. Science 273:1717-1719.
16. Fbw7 ubiquitin ligase. Science 294:173-177.
17. Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
18. Levi G, Aloisi F, Witkin GP (1987) Differentiation of cerebellar bipotential glial precursors into oligodendrocytes in primary culture: developmental profile of surface antigens and mitotic activity. J Neurosci Res 18:407-417.
19. Lin HY, Shih A, Davis FB, Davis PJ (1999) Thyroid hormone promotes the phosphorylation of STAT3 and potentiates the action of epidermal growth factor in cultures cells. Biochem J 338:427-432.
20. Lowry OR, Rosebrough NR, Farr AL, Randall RJ (1951) Protein measurement with Folin phenol reagent. J Biol Chem 193:265-275.
21. Malek RL, Halvorsen SW (1999) Ciliary neurotrophic factor and phorbol ester each decrease selected stat3 pools in neuroblastoma cells by proteasome-dependent mechanisms. Cytokine 11:192-199.
22. Marta CB, Davio C, Pasquini LA, Soto EF, Pasquini JM (2002) Molecular mechanisms involved in the actions of apotransferrin upon the central nervous system: role of the cytoskeleton and of second messengers. J Neurosci Res 69:488-496.
23. McCarthy KD, de Vellis J (1980) Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue. J Cell Biol 85:890-902.
24. Kip1 enhances myelin basic protein gene promoter activity. J Neurosci Res 67:100-105.
25. Montagnoli A, Fiore F, Eytan E, Carrano AC, Draetta GF, Hershko A, Pagano M (1999) Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation. Genes Dev 1:13:1181-1189.
26. Mosmann T (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65:55-63.
27. Noble M, Murray K, Stroobant P, Waterfield MD, Riddle P (1988) Platelet derived growth factor promotes division and motility and inhibits premature differentiation of the oligodendrocyte type-2 astrocyte progenitor cell. Nature 333:560-562.
28. Oberhammer F, Fritsch G, Schimied M, Pavelka M, Prinz D, Purchio T, Lassmann H, Schulte-Hermann R (1993) Condensation of the chromatin at the membrane of an apoptotic nucleus is not associated with activation of an endonuclease. J Cell Sci 104:317-326.
29. Obin M, Mesco E, Gong X, Haas AL, Joseph J, Taylor A (1999) Neurite outgrowth in PC12 cells: distinguishing the roles of ubiquitylation and ubiquitin-dependent proteolysis. J Biol Chem 274:11789-11795.
30. Paez PM, Marta CB, Besio-Moreno M, Soto EF, Pasquini JM (2002) Apotransferrin decreases migration and enhances differentiation of oligodendroglial progenitor cells in an in vitro system. Dev Neurosci 24:47-58.
31. Pagano M, Tam SW, Theodora AM, Beer-Romero P, Del Sal G, Chau V, Yew PR, Draetta GF, Rolfe M (1995) Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. Science 269:682-685.
32. Pfeiffer SE, Warrington AE, Bansal R (1993) The oligodendrocyte and its many cellular processes. Trends Cell Biol 3:191-197.
33. 1-phase progression. Genes Dev 13:1501-1512.
34. Singer JD, Gurian-West M, Clurman B, Roberts JM (1999) Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells. Genes Dev 13:2375-2387.
35. Sommer I, Schachner M (1981) Monoclonal antibodies (O1 to O4) to oligodendrocyte cell surfaces: an immunocytological study in the central nervous system. Dev Biol 83:311-327.
36. Sperber BR, McMorris FA (2001) Fyn tyrosine kinase regulates oligodendroglial cell development but is not required for morphological differentiation of oligodendrocytes. J Neurosci Res 63:303-312.
37. Tang XM, Strocchi P, Cambi F (1998) Changes in the activity of cdk2 and cdk5 accompany differentiation of rat primary oligodendrocytes. J Cell Biochem 68:128-137.
38. Vignais ML, Sadowski HB, Watling D, Rogers NC, Gilman M (1996) Platelet-derived growth factor induces phosphorylation of multiple JAK family kinases and STAT proteins. Mol Cell Biol 16:1759-1769.
39. Wegner M (2000) Transcriptional control in myelinating glia: flavors and spices. Glia 31:1-14.