Absence of macrophage-inflammatory protein-1α delays central nervous system demyelination in the presence of an intact blood-brain barrier

Journal of Immunology

Volumn 167, Issue 5, 2001, Pages 2964-2971

  McMahon, E J ^a   Cook, D N ^a   Suzuki, K ^a   Matsushima, G K ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOATTRACTANT; CHEMOKINE; CHEMOTACTIC FACTOR; CUPRIZONE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCYTE CHEMOTACTIC PROTEIN; RANTES;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; CENTRAL NERVOUS SYSTEM; CHROMOSOMAL LOCALIZATION; CONTROLLED STUDY; CYTOKINE RELEASE; DEMYELINATION; LEUKOCYTE ACTIVATION; MOUSE; NONHUMAN; OLIGODENDROGLIA; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION;

EID: 0035451440     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.167.5.2964     Document Type: Article

References (65)

1. Recent advances in chemokines and chemokine receptors
2. Chemokines: A new classification system and their role in immunity
3. Chemokines and their receptors in neurobiology: Perspectives in physiology and homeostasis
4. Chemokines and leukocyte traffic
5. The cysteine-cysteine family of chemokines RANTES. MIP-1α and MIP-1β induce trypanocidal activity in human macrophages via nitric oxide
6. Chemokines in the CNS: Plurifunctional mediators in diverse states
7. Chemokines and chemokine receptors in CNS pathology
8. Chemokine regulation of inflammatory-mediated nervous system diseases
9. Proinflammatory cytokine, chemokine, and cellular adhesion molecule expression during the acute phase of experimental brain abscess development
10. Sequential expression of chemokines in experimental autoimmune neuritis
11. Central nervous system chemokine expression during Theiler's virus-induced demyelinating disease
12. Infiltration of hematogenous lineage cells into the demyelinating central nervous system of twitcher mice
13. Dynamics of production of MIP-1α. MCP-1 and MIP-2 and potential role of neutralization of these chemokines in the regulation of immune responses during experimental autoimmune neuritis in Lewis rats
14. - T cells and RANTES in virus-induced central nervous system inflammation and demyelination
15. An important role for the chemokine macrophage inflammatory protein-1α in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis
16. MIP-1α and MCP-1 differentially regulate acute and relapsing autoimmune encephalomyelitis as well as Th1/Th2 lymphocyte differentiation
17. Acute and relapsing experimental autoimmune encephalomyelitis are regulated by differential expression of the CC chemokines macrophage inflammatory protein-1α and monocyte chemotactic protein-1
18. Leukocyte recruitment during onset of experimental allergic encephalomyelitis is CCR1 dependent
19. CC chemokine receptor 2 is critical for induction of experimental autoimmune encephalomyelitis
20. Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2
21. Induction of experimental autoimmune encephalomyelitis in C57BL/6 mice deficient in either the chemokine macrophage inflammatory protein-1α or its CCR5 receptor
22. Status spongiosus of CNS and hepatic changes induced by cuprizone (biscyclohexanone oxalyldihydrazone)
23. Microglial/macrophage accumulation during cuprizone-induced demyelination in C57BL/6 mice
24. Central nervous system demyelination and remyelination in the mouse: An ultrastructural study of cuprizone toxicity
25. Demyelination of the superior cerebellar peduncle in the mouse induced by cuprizone
26. Observations on oligodendrocyte degeneration, the resolution of status spongiosus and remyelination in cuprizone intoxication in mice
27. The neurotoxicant, cuprizone, as a model to study demyelination and remyelination in the central nervous system
28. Decrease in oligodendrocyte carbonic anhydrase activity preceding myelin degeneration in cuprizone induced demyelination
29. Induction of myelin-associated glycoprotein mRNA in experimental remyelination
30. Atypical localization of the oligodendrocytic isoform (PI) of glutathione-S-transferase in astrocytes during cuprizone intoxication
31. Mature oligodendrocyte apoptosis precedes IGF-1 production and oligodendrocyte progenitor accumulation and differentiation during demyelination/remyelination
32. Gene expression in brain during cuprizone-induced demyelination and remyelination
33. Rapid upregulation of the Pi isoform of glutathione-S-transferase in mouse brains after withdrawal of the neurotoxicant, cuprizone
34. Expression of carbonic anhydrase II mRNA and protein in oligodendrocytes during toxic demyelination in the young adult mouse
35. Blood-brain barrier permeability to horseradish peroxidase in twitcher and cuprizone-intoxicated mice
36. Blood-brain barrier permeability during cuprizone-induced demyelination: Implications for the pathogenesis of immune-mediated demyelinating diseases
37. Requirement of MIP-1α for an inflammatory response to viral infection
38. Early murine cytomegalovirus (MCMV) infection induces liver natural killer (NK) cell inflammation and protection through macrophage inflammatory protein-1α (MIP-1α)-dependent pathways
39. Murine T lymphocytes incapable of producing macrophage inhibitory protein-1 are impaired in causing graft-versus-host disease across a class 1 but not class 11 major histocompatibility complex barrier
40. + T cells are a biologically relevant source of macrophage inflammatory protein-1α in vivo
41. The chemokine macrophage-inflammatory protein-1α and its receptor CCR1 control pulmonary inflammation and antiviral host defense in paramyxovirus infection
42. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
43. Targeted disruption of the mouse sphingolipid activator protein gene: A complex phenotype, including severe leukodystrophy and wide-spread storage of multiple sphingolipids
44. Insulin-like growth factor-1 inhibits mature oligodendrocyte apoptosis during primary demyelination
45. Episodic demyelination and remyelination: Changes in axonal caliber
46. An apoptotic depletion of oligodendrocytes in the twitcher, a murine model of globoid cell leukodystrophy
47. Chemokine and chemokine receptor expression in the central nervous system
48. Murine astrocytes express a functional chemokine receptor
49. Production and function of monocyte chemoattractant protein-1 and other β-chemokines in murine glial cells
50. Chemokines induce migration and changes in actin polymerization in adult rat brain microglia and a human fetal microglial cell line in vitro
51. TGFβ1 selectively up-regulates CCR1 expression in primary murine astrocytes
52. Differential production of and migratory response to β chemokines by human microglia and astrocytes
53. Macrophage inflammatory protein 1 modulates macrophage function
54. Interleukin-1β promotes repair of the central nervous system
55. Recombinant human interferon-inducible protein 10 is a chemoattractant for human monocytes and T lymphocytes and promotes T cell adhesion to endothelial cells
56. Migration responses of human monocytic cell lines to α- and β-chemokines
57. Biologic activities of the murine β-chemokine TCA3
58. The role of macrophages in demyelination
59. Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis
60. Monocyte chemoattractant protein-1 regulates adhesion molecule expression and cytokine production in human monocytes
61. Macrophage inflammatory protein-2 and KC induce chemokine production by mouse astrocytes
62. β-chemokines enhance parasite uptake and promote nitric oxide-dependent microbiostatic activity in murine inflammatory macrophages infected with Trypanosoma cruzi
63. Astrocytes express functional chemokine receptors
64. Astrocytes as mediators of immune and inflammatory responses in the CNS