Recovery from chronic demyelination by thyroid hormone therapy: Myelinogenesis induction and assessment by diffusion tensor magnetic resonance imaging

Journal of Neuroscience

Volumn 28, Issue 52, 2008, Pages 14189-14201

  Harsan, Laura Adela ^a,b   Steibel, Jérôme ^a   Zaremba, Anita ^c   Agin, Arnaud ^a   Sapin, Rémy ^a   Poulet, Patrick ^a   Guignard, Blandine ^a   Parizel, Nathalie ^a   Grucker, Daniel ^a   Boehm, Nelly ^d   Miller, Robert H ^c   Ghandour, M Said ^a  

^a CNRS   (France)

^b UNIVERSITY OF FREIBURG   (Germany)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d INSERM   (France)

Author keywords

Demyelination therapy; DT MRI; Gliotoxic agent; Myelin; Myelin repair; Oligodendrocytes

Indexed keywords

CUPRIZONE; CYCLINE; LIOTHYRONINE; NERVE CELL ADHESION MOLECULE; OLIGODENDROCYTE TRANSCRIPTION FACTOR 2; SONIC HEDGEHOG PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CELL PROLIFERATION; CONTROLLED STUDY; CONVALESCENCE; DIFFUSION TENSOR IMAGING; DRUG TREATMENT FAILURE; FEMALE; HISTOPATHOLOGY; HORMONAL THERAPY; MOUSE; MULTIPLE SCLEROSIS; NEURAL STEM CELL; NEWBORN; NONHUMAN; OLIGODENDROGLIA; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REMYELINIZATION; TREATMENT OUTCOME;

ANIMALS; ANTIGENS, CD45; BRAIN MAPPING; CARBONIC ANHYDRASE II; CHRONIC DISEASE; CUPRIZONE; DEMYELINATING DISEASES; DIFFUSION MAGNETIC RESONANCE IMAGING; DISEASE MODELS, ANIMAL; FEMALE; HEDGEHOG PROTEINS; MICE; MICE, INBRED C57BL; MICROSCOPY, ELECTRON, TRANSMISSION; MYELIN SHEATH; NERVE TISSUE PROTEINS; NEURAL CELL ADHESION MOLECULE L1; PROLIFERATING CELL NUCLEAR ANTIGEN; RECOVERY OF FUNCTION; SIALIC ACIDS; THYROID HORMONES; TIME FACTORS; TRIIODOTHYRONINE;

EID: 58149375840     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4453-08.2008     Document Type: Article

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