Influence of methylprednisolone on magnetic resonance and histological measures during cuprizone-induced demyelination

Neuroscience Letters

Volumn 483, Issue 1, 2010, Pages 47-52

  Cate, Holly S ^a   Wu, Qi Zhu ^a   Kemper, Dennis ^a   Merlo, Daniel ^a   Wang, Hong Xin ^a   Fang, Ke ^a   Egan, Gary F ^a   Kilpatrick, Trevor J ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Cuprizone; Demyelination; Methylprednisolone

Indexed keywords

CUPRIZONE; METHYLPREDNISOLONE; MYELIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DENSITY; CONTROLLED STUDY; CORPUS CALLOSUM; DEMYELINATION; DIFFUSION TENSOR IMAGING; FEMALE; HISTOLOGY; MICROGLIA; MOUSE; MYELINATION; NEUROFILAMENT; NEUROIMAGING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; OLIGODENDROGLIA; PRIORITY JOURNAL;

ANIMALS; BRAIN; CUPRIZONE; DEMYELINATING DISEASES; FEMALE; GLUCOCORTICOIDS; MAGNETIC RESONANCE IMAGING; METHYLPREDNISOLONE; MICE; MICE, INBRED C57BL; MYELIN SHEATH; NERVE FIBERS, MYELINATED;

EID: 77956181286     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2010.07.060     Document Type: Article

References (31)

1. Alexander A.L., Lee J.E., Lazar M., Field A.S. Diffusion tensor imaging of the brain. Neurotherapeutics 2007, 4:316-329.
2. Antal E.J., Wright C.E.r., Gillespie W.R., Albert K.S. Influence of route of administration on the pharmacokinetics of methylprednisolone. J. Pharmacokinet. Biopharm. 1983, 11:561-576.
3. Arfanakis K., Haughton V.M., Carew J.D., Rogers B.P., Dempsey R.J., Meyerand M.E. Diffusion tensor MR imaging in diffuse axonal injury. AJNR Am. J. Neuroradiol. 2002, 23:794-802.
4. Arzt E., Sauer J., Pollmacher T., Labeur M., Holsboer F., Reul J.M., Stalla G.K. Glucocorticoids suppress interleukin-1 receptor antagonist synthesis following induction by endotoxin. Endocrinology 1994, 134:672-677.
5. Assaf Y., Freidlin R.Z., Rohde G.K., Basser P.J. New modeling and experimental framework to characterize hindered and restricted water diffusion in brain white matter. Magn. Reson. Med. 2004, 52:965-978.
6. Bakshi R., Hutton G.J., Miller J.R., Radue E.W. The use of magnetic resonance imaging in the diagnosis and long-term management of multiple sclerosis. Neurology 2004, 63:S3-11.
7. Barnes P.J. Anti-inflammatory actions of glucocorticoids: molecular mechanisms. Clin. Sci. (Lond.) 1998, 94:557-572.
8. Bergers E., Bot J.C., De Groot C.J., Polman C.H., Lycklama a Nijeholt G.J., Castelijns J.A., van der Valk P., Barkhof F. Axonal damage in the spinal cord of MS patients occurs largely independent of T2 MRI lesions. Neurology 2002, 59:1766-1771.
9. Chari D.M., Zhao C., Kotter M.R., Blakemore W.F., Franklin R.J. Corticosteroids delay remyelination of experimental demyelination in the rodent central nervous system. J. Neurosci. Res. 2006, 83:594-605.
10. Chen T.C., Mackic J.B., McComb J.G., Giannotta S.L., Weiss M.H., Zlokovic B.V. Cellular uptake and transport of methylprednisolone at the blood-brain barrier. Neurosurgery 1996, 38:348-354.
11. de Courten-Myers G.M., Kleinholz M., Wagner K.R., Xi G., Myers R.E. Efficacious experimental stroke treatment with high-dose methylprednisolone. Stroke 1994, 25:487-492. (discussion 493).
12. Diem R., Hobom M., Maier K., Weissert R., Storch M.K., Meyer R., Bahr M. Methylprednisolone increases neuronal apoptosis during autoimmune CNS inflammation by inhibition of an endogenous neuroprotective pathway. J. Neurosci. 2003, 23:6993-7000.
13. Filippi M., Cercignani M., Inglese M., Horsfield M.A., Comi G. Diffusion tensor magnetic resonance imaging in multiple sclerosis. Neurology 2001, 56:304-311.
14. Hiremath M.M., Saito Y., Knapp G.W., Ting J.P., Suzuki K., Matsushima G.K. Microglial/macrophage accumulation during cuprizone-induced demyelination in C57BL/6 mice. J. Neuroimmunol. 1998, 92:38-49.
15. Kalayci O., Cataltepe S., Cataltepe O. The effect of bolus methylprednisolone in prevention of brain edema in hypoxic ischemic brain injury: an experimental study in 7-day-old rat pups. Brain Res. 1992, 569:112-116.
16. Lee J.M., Yan P., Xiao Q., Chen S., Lee K.Y., Hsu C.Y., Xu J. Methylprednisolone protects oligodendrocytes but not neurons after spinal cord injury. J. Neurosci. 2008, 28:3141-3149.
17. Lin S.Z., Chiou T.L., Chiang Y.H., Song W.S. Combined treatment with nicardipine, phenobarbital, and methylprednisolone ameliorates vasogenic brain edema. Acta Neurochir. Suppl. (Wien) 1994, 60:528-530.
18. Marriott M.P., Emery B., Cate H.S., Binder M.D., Kemper D., Wu Q.Z., Kolbe S., Gordon I.R., Wang H.X., Egan G.F., Murray S., Butzkueven H., Kilpatrick T.J. Leukemia inhibitory factor signaling modulates both central nervous system demyelination and myelin repair. Glia 2008, 56:686-698.
19. Pavelko K.D., van Engelen B.G., Rodriguez M. Acceleration in the rate of CNS remyelination in lysolecithin-induced demyelination. J. Neurosci. 1998, 18:2498-2505.
20. Qiao M., Malisza K.L., Del Bigio M.R., Tuor U.I. Correlation of cerebral hypoxic-ischemic T2 changes with tissue alterations in water content and protein extravasation. Stroke 2001, 32:958-963.
21. Schmidt J., Gold R., Schonrock L., Zettl U.K., Hartung H.P., Toyka K.V. T-cell apoptosis in situ in experimental autoimmune encephalomyelitis following methylprednisolone pulse therapy. Brain 2000, 123:1431-1441.
22. Schmidt M., Pauels H.G., Lugering N., Lugering A., Domschke W., Kucharzik T. Glucocorticoids induce apoptosis in human monocytes: potential role of IL-1 beta. J. Immunol. 1999, 163:3484-3490.
23. Sellebjerg F., Frederiksen J.L., Nielsen P.M., Olesen J. Double-blind, randomized, placebo-controlled study of oral, high-dose methylprednisolone in attacks of MS. Neurology 1998, 51:529-534.
24. Slivka A.P, Murphy E.J. High-dose methylprednisolone treatment in experimental focal cerebral ischemia. Exp. Neurol. 2001, 167:166-172.
25. Sloka J.S., Stefanelli M. The mechanism of action of methylprednisolone in the treatment of multiple sclerosis. Mult. Scler. 2005, 11:425-432.
26. Song S.K., Sun S.W., Ju W.K., Lin S.J., Cross A.H., Neufeld A.H. Diffusion tensor imaging detects and differentiates axon and myelin degeneration in mouse optic nerve after retinal ischemia. Neuroimage 2003, 20:1714-1722.
27. Song S.K., Sun S.W., Ramsbottom M.J., Chang C., Russell J., Cross A.H. Dysmyelination revealed through MRI as increased radial (but unchanged axial) diffusion of water. Neuroimage 2002, 17:1429-1436.
28. Song S.K., Yoshino J., Le T.Q., Lin S.J., Sun S.W., Cross A.H., Armstrong R.C. Demyelination increases radial diffusivity in corpus callosum of mouse brain. Neuroimage 2005, 26:132-140.
29. Sun S.W., Liang H.F., Trinkaus K., Cross A.H., Armstrong R.C., Song S.K. Noninvasive detection of cuprizone induced axonal damage and demyelination in the mouse corpus callosum. Magn. Reson. Med. 2006, 55:302-308.
30. Wehling-Henricks M., Lee J.J., Tidball J.G. Prednisolone decreases cellular adhesion molecules required for inflammatory cell infiltration in dystrophin-deficient skeletal muscle. Neuromuscul. Disord. 2004, 14:483-490.
31. Wu Q.Z., Yang Q., Cate H.S., Kemper D., Binder M.D., Wang H.X., Fang K., Quick M.J., Marriott M., Kilpatrick T.J., Egan G.F. MRI identification of the rostral-caudal pattern of pathology within the corpus callosum in the cuprizone mouse model. J. Magn. Reson. Imaging 2008, 27:446-453.