-
2
-
-
0036720034
-
Why does remyelination fail in multiple sclerosis?
-
Franklin, R. J. Why does remyelination fail in multiple sclerosis? Nature Rev. Neurosci. 3, 705-714 (2002).
-
(2002)
Nature Rev Neurosci.
, vol.3
, pp. 705-714
-
-
Franklin, R.J.1
-
3
-
-
0037395114
-
Identification and isolation of multipotential neural progenitor cells from the subcortical white matter of the adult human brain
-
Nunes, M. C. et al. Identification and isolation of multipotential neural progenitor cells from the subcortical white matter of the adult human brain. Nature Med. 9, 439-447 (2003).
-
(2003)
Nature Med.
, vol.9
, pp. 439-447
-
-
Nunes, M.C.1
-
4
-
-
0037437148
-
Postnatal NG2 proteoglycan-expressing progenitor cells are intrinsically multipotent and generate functional neurons
-
Belachew, S. et al. Postnatal NG2 proteoglycan-expressing progenitor cells are intrinsically multipotent and generate functional neurons. J. Cell Biol. 161, 169-186 (2003).
-
(2003)
J. Cell Biol.
, vol.161
, pp. 169-186
-
-
Belachew, S.1
-
5
-
-
78650632445
-
Retinoid X receptor gamma signaling accelerates CNS remyelination
-
Huang, J. K. et al. Retinoid X receptor gamma signaling accelerates CNS remyelination. Nature Neurosci. 14, 45-53 (2011).
-
(2011)
Nature Neurosci.
, vol.14
, pp. 45-53
-
-
Huang, J.K.1
-
6
-
-
0030861649
-
Endogenous progenitors remyelinate demyelinated axons in the adult CNS
-
Gensert, J. M. & Goldman, J. E. Endogenous progenitors remyelinate demyelinated axons in the adult CNS. Neuron 19, 197-203 (1997).
-
(1997)
Neuron
, vol.19
, pp. 197-203
-
-
Gensert, J.M.1
Goldman, J.E.2
-
7
-
-
0034653399
-
Proliferation and differentiation of progenitor cells throughout the intact adult rat spinal cord
-
Horner, P. J. et al. Proliferation and differentiation of progenitor cells throughout the intact adult rat spinal cord. J. Neurosci. 20, 2218-2228 (2000).
-
(2000)
J. Neurosci.
, vol.20
, pp. 2218-2228
-
-
Horner, P.J.1
-
8
-
-
79955388260
-
The complex world of oligodendroglial differentiation inhibitors
-
Kremer, D., Aktas, O., Hartung, H. P. & Kury, P. The complex world of oligodendroglial differentiation inhibitors. Ann. Neurol. 69, 602-618 (2011).
-
(2011)
Ann. Neurol.
, vol.69
, pp. 602-618
-
-
Kremer, D.1
Aktas, O.2
Hartung, H.P.3
Kury, P.4
-
9
-
-
81755179427
-
Mediators of oligodendrocyte differentiation during remyelination
-
Patel, J. R. & Klein, R. S. Mediators of oligodendrocyte differentiation during remyelination. FEBS Lett. 585, 3730-3737 (2011).
-
(2011)
FEBS Lett.
, vol.585
, pp. 3730-3737
-
-
Patel, J.R.1
Klein, R.S.2
-
10
-
-
0037122960
-
Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis
-
Chang, A., Tourtellotte, W. W., Rudick, R. & Trapp, B. D. Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis. N. Engl. J. Med. 346, 165-173 (2002).
-
(2002)
N. Engl. J. Med.
, vol.346
, pp. 165-173
-
-
Chang, A.1
Tourtellotte, W.W.2
Rudick, R.3
Trapp, B.D.4
-
11
-
-
0042338685
-
Dysfunctional oligodendrocyte progenitor cell (OPC) populations may inhibit repopulation of OPC depleted tissue
-
Chari, D. M., Huang, W. L. & Blakemore, W. F. Dysfunctional oligodendrocyte progenitor cell (OPC) populations may inhibit repopulation of OPC depleted tissue. J. Neurosci. Res. 73, 787-793 (2003).
-
(2003)
J. Neurosci. Res.
, vol.73
, pp. 787-793
-
-
Chari, D.M.1
Huang, W.L.2
Blakemore, W.F.3
-
12
-
-
0031962240
-
Chronic stage multiple sclerosis lesions contain a relatively quiescent population of oligodendrocyte precursor cells
-
Wolswijk, G. Chronic stage multiple sclerosis lesions contain a relatively quiescent population of oligodendrocyte precursor cells. J. Neurosci. 18, 601-609 (1998).
-
(1998)
J. Neurosci.
, vol.18
, pp. 601-609
-
-
Wolswijk, G.1
-
13
-
-
46849098585
-
Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis
-
Kuhlmann, T. et al. Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis. Brain 131, 1749-1758 (2008).
-
(2008)
Brain
, vol.131
, pp. 1749-1758
-
-
Kuhlmann, T.1
-
14
-
-
0024787406
-
PDGF and intracellular signaling in the timing of oligodendrocyte differentiation
-
Hart, I. K., Richardson, W. D., Bolsover, S. R. & Raff, M. C. PDGF and intracellular signaling in the timing of oligodendrocyte differentiation. J. Cell Biol. 109, 3411-3417 (1989).
-
(1989)
J. Cell Biol.
, vol.109
, pp. 3411-3417
-
-
Hart, I.K.1
Richardson, W.D.2
Bolsover, S.R.3
Raff, M.C.4
-
15
-
-
0034963497
-
Role of thyroid hormone receptors in timing oligodendrocyte differentiation
-
Billon, N., Tokumoto, Y., Forrest, D. & Raff, M. Role of thyroid hormone receptors in timing oligodendrocyte differentiation. Dev. Biol. 235, 110-120 (2001).
-
(2001)
Dev. Biol.
, vol.235
, pp. 110-120
-
-
Billon, N.1
Tokumoto, Y.2
Forrest, D.3
Raff, M.4
-
16
-
-
0035903457
-
Two molecularly distinct intracellular pathways to oligodendrocyte differentiation: Role of a p53 family protein
-
Tokumoto, Y. M., Tang, D. G. & Raff, M. C. Two molecularly distinct intracellular pathways to oligodendrocyte differentiation: role of a p53 family protein. EMBO J. 20, 5261-5268 (2001).
-
(2001)
EMBO J.
, vol.20
, pp. 5261-5268
-
-
Tokumoto, Y.M.1
Tang, D.G.2
Raff, M.C.3
-
17
-
-
9244242542
-
Thyroid hormone administration enhances remyelination in chronic demyelinating inflammatory disease
-
Fernandez, M. et al. Thyroid hormone administration enhances remyelination in chronic demyelinating inflammatory disease. Proc. Natl Acad. Sci. USA 101, 16363-16368 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 16363-16368
-
-
Fernandez, M.1
-
18
-
-
74749090493
-
Cellular approaches to central nervous system remyelination stimulation: Thyroid hormone to promote myelin repair via endogenous stem and precursor cells
-
Calzà, L., Fernandez, M. & Giardino, L. Cellular approaches to central nervous system remyelination stimulation: thyroid hormone to promote myelin repair via endogenous stem and precursor cells. J. Mol. Endocrinol. 44, 13-23 (2010).
-
(2010)
J. Mol. Endocrinol.
, vol.44
, pp. 13-23
-
-
Calzà, L.1
Fernandez, M.2
Giardino, L.3
-
19
-
-
0028279109
-
A novel role for thyroid hormone, glucocorticoids and retinoic acid in timing oligodendrocyte development
-
Barres, B. A., Lazar, M. A. & Raff, M. C. A novel role for thyroid hormone, glucocorticoids and retinoic acid in timing oligodendrocyte development. Development 120, 1097-1108 (1994).
-
(1994)
Development
, vol.120
, pp. 1097-1108
-
-
Barres, B.A.1
Lazar, M.A.2
Raff, M.C.3
-
20
-
-
77954142973
-
Drug reprofiling using zebrafish identifies novel compounds with potential pro-myelination effects
-
Buckley, C. E. et al. Drug reprofiling using zebrafish identifies novel compounds with potential pro-myelination effects. Neuropharmacology 59, 149-159 (2010).
-
(2010)
Neuropharmacology
, vol.59
, pp. 149-159
-
-
Buckley, C.E.1
-
21
-
-
10744222690
-
Steroids and the reversal of age-associated changes inmyelination and remyelination
-
Ibanez, C. et al. Steroids and the reversal of age-associated changes inmyelination and remyelination. Prog. Neurobiol. 71, 49-56 (2003).
-
(2003)
Prog. Neurobiol.
, vol.71
, pp. 49-56
-
-
Ibanez, C.1
-
22
-
-
60149094000
-
Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcomeby pharmacologicalmodulation of Fyn-RhoA and protein kinase C signalling
-
Baer, A. S. et al. Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcomeby pharmacologicalmodulation of Fyn-RhoA and protein kinase C signalling. Brain 132, 465-481 (2009).
-
(2009)
Brain
, vol.132
, pp. 465-481
-
-
Baer, A.S.1
-
23
-
-
77955477588
-
Chemical inducers and transcriptionalmarkers of oligodendrocyte differentiation
-
Joubert, L. et al.Chemical inducers and transcriptionalmarkers of oligodendrocyte differentiation. J. Neurosci. Res. 88, 2546-2557 (2010).
-
(2010)
J. Neurosci. Res.
, vol.88
, pp. 2546-2557
-
-
Joubert, L.1
-
24
-
-
0025225277
-
Two proliferative stages of the oligodendrocyte lineage (A2B51O42 and O41GalC2) under different mitogenic control
-
Gard, A. L. & Pfeiffer, S. E. Two proliferative stages of the oligodendrocyte lineage (A2B51O42 and O41GalC2) under different mitogenic control. Neuron 5, 615-625 (1990).
-
(1990)
Neuron
, vol.5
, pp. 615-625
-
-
Gard, A.L.1
Pfeiffer, S.E.2
-
25
-
-
0027193569
-
The oligodendrocyte and its many cellular processes
-
Pfeiffer, S. E., Warrington, A. E. & Bansal, R. The oligodendrocyte and its many cellular processes. Trends Cell Biol. 3, 191-197 (1993).
-
(1993)
Trends Cell Biol.
, vol.3
, pp. 191-197
-
-
Pfeiffer, S.E.1
Warrington, A.E.2
Bansal, R.3
-
26
-
-
70349106392
-
Generationof corticalneurons frommouse embryonic stemcells
-
Gaspard, N. et al. Generationof corticalneurons frommouse embryonic stemcells. Nature Protocols 4, 1454-1463 (2009).
-
(2009)
Nature Protocols
, vol.4
, pp. 1454-1463
-
-
Gaspard, N.1
-
27
-
-
0026689930
-
Cell death and control of cell survival in the oligodendrocyte lineage
-
Barres, B. A. et al. Cell death and control of cell survival in the oligodendrocyte lineage. Cell 70, 31-46 (1992).
-
(1992)
Cell
, vol.70
, pp. 31-46
-
-
Barres, B.A.1
-
28
-
-
0028158002
-
Release of dopamine via the human transporter
-
Eshleman, A. J., Henningsen, R. A., Neve, K. A. & Janowsky, A. Release of dopamine via the human transporter. Mol. Pharmacol. 45, 312-316 (1994).
-
(1994)
Mol. Pharmacol.
, vol.45
, pp. 312-316
-
-
Eshleman, A.J.1
Henningsen, R.A.2
Neve, K.A.3
Janowsky, A.4
-
29
-
-
0020048363
-
Stimulant actions of histamine H1 antagonists on operant behavior in the squirrel monkey
-
McKearney, J. W. Stimulant actions of histamine H1 antagonists on operant behavior in the squirrel monkey. Psychopharmacol. 77, 156-158 (1982).
-
(1982)
Psychopharmacol.
, vol.77
, pp. 156-158
-
-
McKearney, J.W.1
-
30
-
-
0031434059
-
Novel N-substituted 3a-[bis(4'-fluorophenyl)methoxy]tropane analogues: Selective ligands for the dopamine transporter
-
Agoston, G. E. et al. Novel N-substituted 3a-[bis(4'-fluorophenyl) methoxy]tropane analogues: selective ligands for the dopamine transporter. J. Med. Chem. 40, 4329-4339 (1997).
-
(1997)
J. Med. Chem.
, vol.40
, pp. 4329-4339
-
-
Agoston, G.E.1
-
31
-
-
84859492260
-
Muscarinic receptor subtypes as potential targets to modulate oligodendrocyte progenitor survival, proliferation and differentiation
-
De Angelis, F., Bernardo, A., Magnaghi, V., Minghetti, L. & Tata, A. M. Muscarinic receptor subtypes as potential targets to modulate oligodendrocyte progenitor survival, proliferation and differentiation. Dev. Neurobiol. 72, 713-728 (2012).
-
(2012)
Dev. Neurobiol.
, vol.72
, pp. 713-728
-
-
De Angelis, F.1
Bernardo, A.2
Magnaghi, V.3
Minghetti, L.4
Tata, A.M.5
-
32
-
-
4344625746
-
Notch1 and Jagged1 are expressed after CNS demyelination, but are not a major rate-determining factor during remyelination
-
Stidworthy, M. F. et al. Notch1 and Jagged1 are expressed after CNS demyelination, but are not a major rate-determining factor during remyelination. Brain 127, 1928-1941 (2004).
-
(2004)
Brain
, vol.127
, pp. 1928-1941
-
-
Stidworthy, M.F.1
-
33
-
-
77952242933
-
Signals to promote myelin formation and repair
-
Taveggia, C., Feltri, M. L. & Wrabetz, L. Signals to promote myelin formation and repair. Nature Rev. Neurol. 6, 276-287 (2010).
-
(2010)
Nature Rev. Neurol.
, vol.6
, pp. 276-287
-
-
Taveggia, C.1
Feltri, M.L.2
Wrabetz, L.3
-
34
-
-
0035016227
-
Pharmacological and functional characterization of muscarinic receptor subtypes in developing oligodendrocytes
-
Ragheb, F. et al. Pharmacological and functional characterization of muscarinic receptor subtypes in developing oligodendrocytes. J. Neurochem. 77, 1396-1406 (2001).
-
(2001)
J. Neurochem.
, vol.77
, pp. 1396-1406
-
-
Ragheb, F.1
-
35
-
-
0029013930
-
Muscarinic acetylcholine receptors: Signal transduction through multiple effectors
-
Felder, C. C. Muscarinic acetylcholine receptors: signal transduction through multiple effectors. FASEB J. 9, 619-625 (1995).
-
(1995)
FASEB J.
, vol.9
, pp. 619-625
-
-
Felder, C.C.1
-
36
-
-
0028959239
-
The immunology ofmultiple sclerosis and its animalmodel, experimental allergic encephalomyelitis
-
Owens, T. & Sriram, S. The immunology ofmultiple sclerosis and its animalmodel, experimental allergic encephalomyelitis. Neurol. Clin. 13, 51-73 (1995).
-
(1995)
Neurol. Clin.
, vol.13
, pp. 51-73
-
-
Owens, T.1
Sriram, S.2
-
37
-
-
34247148164
-
Inhibition of transmethylation down-regulates CD4 T cell activation and curtails development of autoimmunity in a model system
-
Lawson, B. R. et al. Inhibition of transmethylation down-regulates CD4 T cell activation and curtails development of autoimmunity in a model system. J. Immunol. 178, 5366-5374 (2007).
-
(2007)
J. Immunol.
, vol.178
, pp. 5366-5374
-
-
Lawson, B.R.1
-
38
-
-
64149114563
-
Animalmodels ofmultiple sclerosis for the development and validation of novel therapies-potential and limitations
-
Mix, E.,Meyer-Rienecker, H. & Zettl, U. K.Animalmodels ofmultiple sclerosis for the development and validation of novel therapies-potential and limitations. J. Neurol. 255 (Suppl 6), 7-14 (2008).
-
(2008)
J. Neurol.
, vol.255
, Issue.SUPPL. 6
, pp. 7-14
-
-
Mix, E.1
Meyer-Rienecker, H.2
Zettl, U.K.3
-
39
-
-
28444499085
-
Virtues and pitfalls of EAE for the development of therapies for multiple sclerosis
-
Steinman, L. & Zamvil, S. S. Virtues and pitfalls of EAE for the development of therapies for multiple sclerosis. Trends Immunol. 26, 565-571 (2005).
-
(2005)
Trends Immunol.
, vol.26
, pp. 565-571
-
-
Steinman, L.1
Zamvil, S.S.2
-
40
-
-
80755139618
-
Distinct pathological patterns in relapsing-remitting and chronic models of experimental autoimmune enchephalomyelitis and the neuroprotective effect of glatiramer acetate
-
Aharoni, R. et al. Distinct pathological patterns in relapsing-remitting and chronic models of experimental autoimmune enchephalomyelitis and the neuroprotective effect of glatiramer acetate. J. Autoimmun. 37, 228-241 (2011).
-
(2011)
J. Autoimmun.
, vol.37
, pp. 228-241
-
-
Aharoni, R.1
-
41
-
-
77954473191
-
Myelin repair is accelerated by inactivating CXCR2 on nonhematopoietic cells
-
Liu, L. et al. Myelin repair is accelerated by inactivating CXCR2 on nonhematopoietic cells. J. Neurosci. 30, 9074-9083 (2010).
-
(2010)
J. Neurosci.
, vol.30
, pp. 9074-9083
-
-
Liu, L.1
-
42
-
-
34948888764
-
LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis
-
Mi, S. et al. LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis. Nature Med. 13, 1228-1233 (2007).
-
(2007)
Nature Med.
, vol.13
, pp. 1228-1233
-
-
Mi, S.1
-
43
-
-
40549097040
-
Basic and clinical aspects of non-neuronal acetylcholine: Overview of non-neuronal cholinergic systems and their biological significance
-
Kawashima, K. & Fujii, T. Basic and clinical aspects of non-neuronal acetylcholine: overview of non-neuronal cholinergic systems and their biological significance. J. Pharmacol. Sci. 106, 167-173 (2008).
-
(2008)
J. Pharmacol. Sci.
, vol.106
, pp. 167-173
-
-
Kawashima, K.1
Fujii, T.2
-
44
-
-
78049267645
-
Promoting tolerance to proteolipid protein-induced experimental autoimmune encephalomyelitis through targeting dendritic cells
-
Stern, J. N. et al. Promoting tolerance to proteolipid protein-induced experimental autoimmune encephalomyelitis through targeting dendritic cells. Proc. Natl Acad. Sci. USA 107, 17280-17285 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 17280-17285
-
-
Stern, J.N.1
-
45
-
-
83155192141
-
Demyelination and remyelination in anatomically distinct regions of the corpus callosum following cuprizone intoxication
-
Steelman, A. J., Thompson, J. P. & Li, J. Demyelination and remyelination in anatomically distinct regions of the corpus callosum following cuprizone intoxication. Neurosci. Res. 72, 32-42 (2012).
-
(2012)
Neurosci. Res.
, vol.72
, pp. 32-42
-
-
Steelman, A.J.1
Thompson, J.P.2
Li, J.3
-
46
-
-
0035198691
-
The neurotoxicant, cuprizone, as a model to study demyelination and remyelination in the central nervous system
-
Matsushima, G. K. & Morell, P. The neurotoxicant, cuprizone, as a model to study demyelination and remyelination in the central nervous system. Brain Pathol. 11, 107-116 (2001).
-
(2001)
Brain Pathol.
, vol.11
, pp. 107-116
-
-
Matsushima, G.K.1
Morell, P.2
-
47
-
-
77955799815
-
Oral fingolimod (FTY720) for relapsingmultiple sclerosis
-
Kappos, L. et al. Oral fingolimod (FTY720) for relapsingmultiple sclerosis. N. Engl. J. Med. 355, 1124-1140 (2006).
-
(2006)
N. Engl. J. Med.
, vol.355
, pp. 1124-1140
-
-
Kappos, L.1
-
48
-
-
0037181634
-
Every-other-day interferon beta-1b versus once-weekly interferon beta-1a for multiple sclerosis: Results of a 2-year prospective randomised multicentre study (INCOMIN)
-
Durelli, L. et al. Every-other-day interferon beta-1b versus once-weekly interferon beta-1a for multiple sclerosis: results of a 2-year prospective randomised multicentre study (INCOMIN). Lancet 359, 1453-1460 (2002).
-
(2002)
Lancet
, vol.359
, pp. 1453-1460
-
-
Durelli, L.1
-
49
-
-
0027366326
-
Interferon b decreases T cell activation and interferon c production in multiple sclerosis
-
Noronha, A., Toscas, A. & Jensen, M. A. Interferon b decreases T cell activation and interferon c production in multiple sclerosis. J. Neuroimmunol. 46, 145-153 (1993).
-
(1993)
J. Neuroimmunol.
, vol.46
, pp. 145-153
-
-
Noronha, A.1
Toscas, A.2
Jensen, M.A.3
-
50
-
-
0037077308
-
The immune modulator FTY720 targets sphingosine 1-phosphate receptors
-
Brinkmann, V. et al. The immune modulator FTY720 targets sphingosine 1-phosphate receptors. J. Biol. Chem. 277, 21453-21457 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 21453-21457
-
-
Brinkmann, V.1
-
51
-
-
0034595233
-
The Id4 HLH protein and the timing of oligodendrocyte differentiation
-
Kondo, T. & Raff, M. The Id4 HLH protein and the timing of oligodendrocyte differentiation. EMBO J. 19, 1998-2007 (2000).
-
(2000)
EMBO J.
, vol.19
, pp. 1998-2007
-
-
Kondo, T.1
Raff, M.2
-
52
-
-
0035052390
-
A role for the helixloop- helix protein Id2 in the control of oligodendrocyte development
-
Wang, S., Sdrulla, A., Johnson, J. E., Yokota, Y. & Barres, B. A. A role for the helixloop- helix protein Id2 in the control of oligodendrocyte development. Neuron 29, 603-614 (2001).
-
(2001)
Neuron
, vol.29
, pp. 603-614
-
-
Wang, S.1
Sdrulla, A.2
Johnson, J.E.3
Yokota, Y.4
Barres, B.A.5
-
53
-
-
84872966938
-
Neuron-oligodendrocyte myelination co-culture derived from embryonic rat spinal cord and cerebral cortex
-
Pang, Y. et al. Neuron-oligodendrocyte myelination co-culture derived from embryonic rat spinal cord and cerebral cortex. Brain Behav. 2, 53-67 (2012).
-
(2012)
Brain Behav.
, vol.2
, pp. 53-67
-
-
Pang, Y.1
-
54
-
-
33847275635
-
Human oligodendrocytes derived from embryonic stem cells: Effect of noggin on phenotypic differentiation in vitro and on myelination in vivo
-
Izrael, M. et al. Human oligodendrocytes derived from embryonic stem cells: Effect of noggin on phenotypic differentiation in vitro and on myelination in vivo. Mol. Cell. Neurosci. 34, 310-323 (2007).
-
(2007)
Mol. Cell. Neurosci.
, vol.34
, pp. 310-323
-
-
Izrael, M.1
|