메뉴 건너뛰기




Volumn 7, Issue 3, 2012, Pages

Galanin transgenic mice with elevated circulating galanin levels alleviate demyelination in a cuprizone-induced ms mouse model

Author keywords

[No Author keywords available]

Indexed keywords

CUPRIZONE; GALANIN; GALANIN RECEPTOR 1; GALANIN RECEPTOR 2; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; MONOAMINE OXIDASE INHIBITOR;

EID: 84863376198     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0033901     Document Type: Article
Times cited : (25)

References (42)
  • 1
    • 0345633543 scopus 로고    scopus 로고
    • A quantitative analysis of oligodendrocytes in multiple sclerosis lesions. A study of 113 cases
    • Lucchinetti C, Bruck W, Parisi J, Scheithauer B, Rodriguez M, et al. (1999) A quantitative analysis of oligodendrocytes in multiple sclerosis lesions. A study of 113 cases. Brain 122 (Pt 12): 2279-2295.
    • (1999) Brain , vol.122 , Issue.Pt 12 , pp. 2279-2295
    • Lucchinetti, C.1    Bruck, W.2    Parisi, J.3    Scheithauer, B.4    Rodriguez, M.5
  • 3
    • 0032984667 scopus 로고    scopus 로고
    • The origin of remyelinating cells in the central nervous system
    • Blakemore WF, Keirstead HS, (1999) The origin of remyelinating cells in the central nervous system. J Neuroimmunol 98: 69-76.
    • (1999) J Neuroimmunol , vol.98 , pp. 69-76
    • Blakemore, W.F.1    Keirstead, H.S.2
  • 4
    • 27644552194 scopus 로고    scopus 로고
    • Cortical demyelination and diffuse white matter injury in multiple sclerosis
    • Kutzelnigg A, Lucchinetti CF, Stadelmann C, Bruck W, Rauschka H, et al. (2005) Cortical demyelination and diffuse white matter injury in multiple sclerosis. Brain 128: 2705-2712.
    • (2005) Brain , vol.128 , pp. 2705-2712
    • Kutzelnigg, A.1    Lucchinetti, C.F.2    Stadelmann, C.3    Bruck, W.4    Rauschka, H.5
  • 6
    • 0042123685 scopus 로고    scopus 로고
    • Intracortical multiple sclerosis lesions are not associated with increased lymphocyte infiltration
    • Bo L, Vedeler CA, Nyland H, Trapp BD, Mork SJ, (2003) Intracortical multiple sclerosis lesions are not associated with increased lymphocyte infiltration. Mult Scler 9: 323-331.
    • (2003) Mult Scler , vol.9 , pp. 323-331
    • Bo, L.1    Vedeler, C.A.2    Nyland, H.3    Trapp, B.D.4    Mork, S.J.5
  • 8
    • 79952994824 scopus 로고    scopus 로고
    • Targeting oligodendrocyte protection and remyelination in multiple sclerosis
    • Zhang J, Kramer EG, Mahase S, Dutta DJ, Bonnamain V, et al. (2011) Targeting oligodendrocyte protection and remyelination in multiple sclerosis. Mt Sinai J Med 78: 244-257.
    • (2011) Mt Sinai J Med , vol.78 , pp. 244-257
    • Zhang, J.1    Kramer, E.G.2    Mahase, S.3    Dutta, D.J.4    Bonnamain, V.5
  • 10
    • 34447255940 scopus 로고    scopus 로고
    • The galanin peptide family: receptor pharmacology, pleiotropic biological actions, and implications in health and disease
    • Lang R, Gundlach AL, Kofler B, (2007) The galanin peptide family: receptor pharmacology, pleiotropic biological actions, and implications in health and disease. Pharmacol Ther 115: 177-207.
    • (2007) Pharmacol Ther , vol.115 , pp. 177-207
    • Lang, R.1    Gundlach, A.L.2    Kofler, B.3
  • 11
    • 45849091110 scopus 로고    scopus 로고
    • Galanin acts as a trophic factor to the central and peripheral nervous systems
    • Hobson SA, Bacon A, Elliot-Hunt CR, Holmes FE, Kerr NC, et al. (2008) Galanin acts as a trophic factor to the central and peripheral nervous systems. Cell Mol Life Sci 65: 1806-1812.
    • (2008) Cell Mol Life Sci , vol.65 , pp. 1806-1812
    • Hobson, S.A.1    Bacon, A.2    Elliot-Hunt, C.R.3    Holmes, F.E.4    Kerr, N.C.5
  • 12
    • 0141482015 scopus 로고    scopus 로고
    • Expression and plasticity of galanin systems in cortical neurons, oligodendrocyte progenitors and proliferative zones in normal brain and after spreading depression
    • Shen PJ, Larm JA, Gundlach AL, (2003) Expression and plasticity of galanin systems in cortical neurons, oligodendrocyte progenitors and proliferative zones in normal brain and after spreading depression. Eur J Neurosci 18: 1362-1376.
    • (2003) Eur J Neurosci , vol.18 , pp. 1362-1376
    • Shen, P.J.1    Larm, J.A.2    Gundlach, A.L.3
  • 14
    • 4444310169 scopus 로고    scopus 로고
    • Patterns of seizures, hippocampal injury and neurogenesis in three models of status epilepticus in galanin receptor type 1 (GalR1) knockout mice
    • Mazarati A, Lu X, Shinmei S, Badie-Mahdavi H, Bartfai T, (2004) Patterns of seizures, hippocampal injury and neurogenesis in three models of status epilepticus in galanin receptor type 1 (GalR1) knockout mice. Neuroscience 128: 431-441.
    • (2004) Neuroscience , vol.128 , pp. 431-441
    • Mazarati, A.1    Lu, X.2    Shinmei, S.3    Badie-Mahdavi, H.4    Bartfai, T.5
  • 15
    • 20444398172 scopus 로고    scopus 로고
    • Galanin in neuro(glio)genesis: expression of galanin and receptors by progenitor cells in vivo and in vitro and effects of galanin on neurosphere proliferation
    • Shen PJ, Yuan CG, Ma J, Cheng S, Yao M, et al. (2005) Galanin in neuro(glio)genesis: expression of galanin and receptors by progenitor cells in vivo and in vitro and effects of galanin on neurosphere proliferation. Neuropeptides 39: 201-205.
    • (2005) Neuropeptides , vol.39 , pp. 201-205
    • Shen, P.J.1    Yuan, C.G.2    Ma, J.3    Cheng, S.4    Yao, M.5
  • 16
    • 15244355507 scopus 로고    scopus 로고
    • Induction of galanin receptor-1 (GalR1) expression in external granule cell layer of post-natal mouse cerebellum
    • Jungnickel SR, Yao M, Shen PJ, Gundlach AL, (2005) Induction of galanin receptor-1 (GalR1) expression in external granule cell layer of post-natal mouse cerebellum. J Neurochem 92: 1452-1462.
    • (2005) J Neurochem , vol.92 , pp. 1452-1462
    • Jungnickel, S.R.1    Yao, M.2    Shen, P.J.3    Gundlach, A.L.4
  • 17
    • 3042841020 scopus 로고    scopus 로고
    • Galanin type 2 receptors regulate neuronal survival, susceptibility to seizures and seizure-induced neurogenesis in the dentate gyrus
    • Mazarati A, Lu X, Kilk K, Langel U, Wasterlain C, et al. (2004) Galanin type 2 receptors regulate neuronal survival, susceptibility to seizures and seizure-induced neurogenesis in the dentate gyrus. Eur J Neurosci 19: 3235-3244.
    • (2004) Eur J Neurosci , vol.19 , pp. 3235-3244
    • Mazarati, A.1    Lu, X.2    Kilk, K.3    Langel, U.4    Wasterlain, C.5
  • 18
    • 0242317366 scopus 로고    scopus 로고
    • Neuro'-peptides in glia: focus on NPY and galanin
    • Ubink R, Calza L, Hokfelt T, (2003) 'Neuro'-peptides in glia: focus on NPY and galanin. Trends Neurosci 26: 604-609.
    • (2003) Trends Neurosci , vol.26 , pp. 604-609
    • Ubink, R.1    Calza, L.2    Hokfelt, T.3
  • 20
    • 0035198691 scopus 로고    scopus 로고
    • The neurotoxicant, cuprizone, as a model to study demyelination and remyelination in the central nervous system
    • Matsushima GK, Morell P, (2001) The neurotoxicant, cuprizone, as a model to study demyelination and remyelination in the central nervous system. Brain Pathol 11: 107-116.
    • (2001) Brain Pathol , vol.11 , pp. 107-116
    • Matsushima, G.K.1    Morell, P.2
  • 21
    • 0342906187 scopus 로고    scopus 로고
    • Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination
    • Lucchinetti C, Bruck W, Parisi J, Scheithauer B, Rodriguez M, et al. (2000) Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination. Ann Neurol 47: 707-717.
    • (2000) Ann Neurol , vol.47 , pp. 707-717
    • Lucchinetti, C.1    Bruck, W.2    Parisi, J.3    Scheithauer, B.4    Rodriguez, M.5
  • 22
    • 0344898855 scopus 로고    scopus 로고
    • Transgenic mice over-expressing galanin exhibit pituitary adenomas and increased secretion of galanin, prolactin and growth hormone
    • Perumal P, Vrontakis ME, (2003) Transgenic mice over-expressing galanin exhibit pituitary adenomas and increased secretion of galanin, prolactin and growth hormone. J Endocrinol 179: 145-154.
    • (2003) J Endocrinol , vol.179 , pp. 145-154
    • Perumal, P.1    Vrontakis, M.E.2
  • 23
    • 72049093475 scopus 로고    scopus 로고
    • Chronic increase of circulating galanin levels induces obesity and marked alterations in lipid metabolism similar to metabolic syndrome
    • Poritsanos NJ, Mizuno TM, Lautatzis ME, Vrontakis M, (2009) Chronic increase of circulating galanin levels induces obesity and marked alterations in lipid metabolism similar to metabolic syndrome. Int J Obes (Lond) 33: 1381-1389.
    • (2009) Int J Obes (Lond) , vol.33 , pp. 1381-1389
    • Poritsanos, N.J.1    Mizuno, T.M.2    Lautatzis, M.E.3    Vrontakis, M.4
  • 25
    • 0027322295 scopus 로고
    • Serum proteins bypass the blood-brain fluid barriers for extracellular entry to the central nervous system
    • Broadwell RD, Sofroniew MV, (1993) Serum proteins bypass the blood-brain fluid barriers for extracellular entry to the central nervous system. Exp Neurol 120: 245-263.
    • (1993) Exp Neurol , vol.120 , pp. 245-263
    • Broadwell, R.D.1    Sofroniew, M.V.2
  • 26
    • 0028641491 scopus 로고
    • Peptides and the blood-brain barrier: the status of our understanding
    • Begley DJ, (1994) Peptides and the blood-brain barrier: the status of our understanding. Ann N Y Acad Sci 739: 89-100.
    • (1994) Ann N Y Acad Sci , vol.739 , pp. 89-100
    • Begley, D.J.1
  • 27
    • 3042681764 scopus 로고    scopus 로고
    • Intravenous administration of the neuropeptide galanin has fast antidepressant efficacy and affects the sleep EEG
    • Murck H, Held K, Ziegenbein M, Kunzel H, Holsboer F, et al. (2004) Intravenous administration of the neuropeptide galanin has fast antidepressant efficacy and affects the sleep EEG. Psychoneuroendocrinology 29: 1205-1211.
    • (2004) Psychoneuroendocrinology , vol.29 , pp. 1205-1211
    • Murck, H.1    Held, K.2    Ziegenbein, M.3    Kunzel, H.4    Holsboer, F.5
  • 28
    • 37549007582 scopus 로고    scopus 로고
    • Wrapping it up: the cell biology of myelination
    • Simons M, Trotter J, (2007) Wrapping it up: the cell biology of myelination. Curr Opin Neurobiol 17: 533-540.
    • (2007) Curr Opin Neurobiol , vol.17 , pp. 533-540
    • Simons, M.1    Trotter, J.2
  • 29
    • 0034328694 scopus 로고    scopus 로고
    • [Myelin basic protein. Structure, properties, function and role in diagnosing demyelinating diseases]
    • Chekhonin VP, Gurina OI, Dmitrieva TB, Semenova AV, Savchenko EA, et al. (2000) [Myelin basic protein. Structure, properties, function and role in diagnosing demyelinating diseases]. Vopr Med Khim 46: 549-563.
    • (2000) Vopr Med Khim , vol.46 , pp. 549-563
    • Chekhonin, V.P.1    Gurina, O.I.2    Dmitrieva, T.B.3    Semenova, A.V.4    Savchenko, E.A.5
  • 30
    • 0026006754 scopus 로고
    • A pi form of glutathione-S-transferase is a myelin- and oligodendrocyte-associated enzyme in mouse brain
    • Tansey FA, Cammer W, (1991) A pi form of glutathione-S-transferase is a myelin- and oligodendrocyte-associated enzyme in mouse brain. J Neurochem 57: 95-102.
    • (1991) J Neurochem , vol.57 , pp. 95-102
    • Tansey, F.A.1    Cammer, W.2
  • 31
    • 56049125007 scopus 로고    scopus 로고
    • Quetiapine alleviates the cuprizone-induced white matter pathology in the brain of C57BL/6 mouse
    • Zhang Y, Xu H, Jiang W, Xiao L, Yan B, et al. (2008) Quetiapine alleviates the cuprizone-induced white matter pathology in the brain of C57BL/6 mouse. Schizophr Res 106: 182-191.
    • (2008) Schizophr Res , vol.106 , pp. 182-191
    • Zhang, Y.1    Xu, H.2    Jiang, W.3    Xiao, L.4    Yan, B.5
  • 32
    • 78650177929 scopus 로고    scopus 로고
    • Cells of the oligodendroglial lineage, myelination, and remyelination
    • Miron VE, Kuhlmann T, Antel JP, (2011) Cells of the oligodendroglial lineage, myelination, and remyelination. Biochim Biophys Acta 1812: 184-193.
    • (2011) Biochim Biophys Acta , vol.1812 , pp. 184-193
    • Miron, V.E.1    Kuhlmann, T.2    Antel, J.P.3
  • 33
    • 1642281535 scopus 로고    scopus 로고
    • Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion
    • Barnett MH, Prineas JW, (2004) Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion. Ann Neurol 55: 458-468.
    • (2004) Ann Neurol , vol.55 , pp. 458-468
    • Barnett, M.H.1    Prineas, J.W.2
  • 34
    • 69549095826 scopus 로고    scopus 로고
    • Pregnancy, prolactin and white matter regeneration
    • Gregg C, (2009) Pregnancy, prolactin and white matter regeneration. J Neurol Sci 285: 22-27.
    • (2009) J Neurol Sci , vol.285 , pp. 22-27
    • Gregg, C.1
  • 35
    • 33847200751 scopus 로고    scopus 로고
    • White matter plasticity and enhanced remyelination in the maternal CNS
    • Gregg C, Shikar V, Larsen P, Mak G, Chojnacki A, et al. (2007) White matter plasticity and enhanced remyelination in the maternal CNS. J Neurosci 27: 1812-1823.
    • (2007) J Neurosci , vol.27 , pp. 1812-1823
    • Gregg, C.1    Shikar, V.2    Larsen, P.3    Mak, G.4    Chojnacki, A.5
  • 36
    • 34948851428 scopus 로고    scopus 로고
    • Protective and regenerative effects of the GH/IGF-I axis on the brain
    • Isgaard J, Aberg D, Nilsson M, (2007) Protective and regenerative effects of the GH/IGF-I axis on the brain. Minerva Endocrinol 32: 103-113.
    • (2007) Minerva Endocrinol , vol.32 , pp. 103-113
    • Isgaard, J.1    Aberg, D.2    Nilsson, M.3
  • 37
    • 77955396793 scopus 로고    scopus 로고
    • Role of the growth hormone/insulin-like growth factor 1 axis in neurogenesis
    • Aberg D, (2010) Role of the growth hormone/insulin-like growth factor 1 axis in neurogenesis. Endocr Dev 17: 63-76.
    • (2010) Endocr Dev , vol.17 , pp. 63-76
    • Aberg, D.1
  • 38
    • 0036709433 scopus 로고    scopus 로고
    • Peripheral macrophage recruitment in cuprizone-induced CNS demyelination despite an intact blood-brain barrier
    • McMahon EJ, Suzuki K, Matsushima GK, (2002) Peripheral macrophage recruitment in cuprizone-induced CNS demyelination despite an intact blood-brain barrier. J Neuroimmunol 130: 32-45.
    • (2002) J Neuroimmunol , vol.130 , pp. 32-45
    • McMahon, E.J.1    Suzuki, K.2    Matsushima, G.K.3
  • 40
    • 3142686631 scopus 로고    scopus 로고
    • Galmic, a nonpeptide galanin receptor agonist, affects behaviors in seizure, pain, and forced-swim tests
    • Bartfai T, Lu X, Badie-Mahdavi H, Barr AM, Mazarati A, et al. (2004) Galmic, a nonpeptide galanin receptor agonist, affects behaviors in seizure, pain, and forced-swim tests. Proc Natl Acad Sci U S A 101: 10470-10475.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 10470-10475
    • Bartfai, T.1    Lu, X.2    Badie-Mahdavi, H.3    Barr, A.M.4    Mazarati, A.5
  • 42
    • 84863387858 scopus 로고    scopus 로고
    • National Institutes of Health Image J website. Image J user guide
    • Available: Accessed 2011 May 01
    • National Institutes of Health Image J website. Image J user guide. Available: http://rsbweb.nih.gov/ij/docs/user-guide.pdf. Accessed 2011 May 01.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.