-
1
-
-
65349103899
-
Blinded by the light: The growing complexity of p53
-
K.H. Vousden, and C. Prives Blinded by the light: the growing complexity of p53 Cell 137 2009 413 431
-
(2009)
Cell
, vol.137
, pp. 413-431
-
-
Vousden, K.H.1
Prives, C.2
-
2
-
-
84903269985
-
P53 and mitochondrial function in neurons
-
D.B. Wang, C. Kinoshita, Y. Kinoshita, and R.S. Morrison p53 and mitochondrial function in neurons Biochimica et Biophysica Acta 1842 8 2014 1186 1197 10.1016/j.bbadis.2013.12.015
-
(2014)
Biochimica et Biophysica Acta
, vol.1842
, Issue.8
, pp. 1186-1197
-
-
Wang, D.B.1
Kinoshita, C.2
Kinoshita, Y.3
Morrison, R.S.4
-
4
-
-
79952280229
-
P53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase
-
P. Jiang, W. Du, X. Wang, A. Mancuso, X. Gao, and M. Wu p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase Nature Cell Biology 13 2011 310 316
-
(2011)
Nature Cell Biology
, vol.13
, pp. 310-316
-
-
Jiang, P.1
Du, W.2
Wang, X.3
Mancuso, A.4
Gao, X.5
Wu, M.6
-
5
-
-
33745918951
-
TIGAR, a p53-inducible regulator of glycolysis and apoptosis
-
K. Bensaad, A. Tsuruta, M.A. Selak, M.N. Vidal, K. Nakano, and R. Bartrons TIGAR, a p53-inducible regulator of glycolysis and apoptosis Cell 126 2006 107 120
-
(2006)
Cell
, vol.126
, pp. 107-120
-
-
Bensaad, K.1
Tsuruta, A.2
Selak, M.A.3
Vidal, M.N.4
Nakano, K.5
Bartrons, R.6
-
6
-
-
70349445170
-
Abrams JM. P53 ancestry: Gazing through an evolutionary lens
-
W.J. Lu, and J.F. Amatruda Abrams JM. p53 ancestry: gazing through an evolutionary lens Nature Reviews. Cancer 9 2009 758 762
-
(2009)
Nature Reviews. Cancer
, vol.9
, pp. 758-762
-
-
Lu, W.J.1
Amatruda, J.F.2
-
8
-
-
1942506067
-
The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression
-
F. Schwartzenberg-Bar-Yoseph, M. Armoni, and E. Karnieli The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression Cancer Research 64 2004 2627 2633
-
(2004)
Cancer Research
, vol.64
, pp. 2627-2633
-
-
Schwartzenberg-Bar-Yoseph, F.1
Armoni, M.2
Karnieli, E.3
-
9
-
-
43049139541
-
P53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation
-
K. Kawauchi, K. Araki, K. Tobiume, and N. Tanaka p53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation Nature Cell Biology 10 2008 611 618
-
(2008)
Nature Cell Biology
, vol.10
, pp. 611-618
-
-
Kawauchi, K.1
Araki, K.2
Tobiume, K.3
Tanaka, N.4
-
10
-
-
84881453767
-
TAp73 enhances the pentose phosphate pathway and supports cell proliferation
-
W. Du, P. Jiang, A. Mancuso, A. Stonestrom, M.D. Brewer, and A.J. Minn TAp73 enhances the pentose phosphate pathway and supports cell proliferation Nature Cell Biology 15 2013 991 1000
-
(2013)
Nature Cell Biology
, vol.15
, pp. 991-1000
-
-
Du, W.1
Jiang, P.2
Mancuso, A.3
Stonestrom, A.4
Brewer, M.D.5
Minn, A.J.6
-
11
-
-
11244347171
-
Glycolytic enzymes can modulate cellular life span
-
H. Kondoh, M.E. Lleonart, J. Gil, J. Wang, P. Degan, and G. Peters Glycolytic enzymes can modulate cellular life span Cancer Research 65 2005 177 185
-
(2005)
Cancer Research
, vol.65
, pp. 177-185
-
-
Kondoh, H.1
Lleonart, M.E.2
Gil, J.3
Wang, J.4
Degan, P.5
Peters, G.6
-
12
-
-
0032975551
-
P53 is a transcriptional activator of the muscle-specific phosphoglycerate mutase gene and contributes in vivo to the control of its cardiac expression
-
P. Ruiz-Lozano, M.L. Hixon, M.W. Wagner, A.I. Flores, S. Ikawa, and A.S. Baldwin Jr. p53 is a transcriptional activator of the muscle-specific phosphoglycerate mutase gene and contributes in vivo to the control of its cardiac expression Cell Growth & Differentiation: The Molecular Biology Journal of the American Association for Cancer Research 10 1999 295 306
-
(1999)
Cell Growth & Differentiation: The Molecular Biology Journal of the American Association for Cancer Research
, vol.10
, pp. 295-306
-
-
Ruiz-Lozano, P.1
Hixon, M.L.2
Wagner, M.W.3
Flores, A.I.4
Ikawa, S.5
Baldwin, A.S.6
-
13
-
-
33746924468
-
Hexokinase II: Cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria
-
S.P. Mathupala, Y.H. Ko, and P.L. Pedersen Hexokinase II: cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria Oncogene 25 2006 4777 4786
-
(2006)
Oncogene
, vol.25
, pp. 4777-4786
-
-
Mathupala, S.P.1
Ko, Y.H.2
Pedersen, P.L.3
-
14
-
-
84904687584
-
Tumor suppressor p53 cooperates with SIRT6 to regulate gluconeogenesis by promoting FoxO1 nuclear exclusion
-
P. Zhang, B. Tu, H. Wang, Z. Cao, M. Tang, and C. Zhang Tumor suppressor p53 cooperates with SIRT6 to regulate gluconeogenesis by promoting FoxO1 nuclear exclusion Proceedings of the National Academy of Sciences of the United States of America 111 2014 10684 10689
-
(2014)
Proceedings of the National Academy of Sciences of the United States of America
, vol.111
, pp. 10684-10689
-
-
Zhang, P.1
Tu, B.2
Wang, H.3
Cao, Z.4
Tang, M.5
Zhang, C.6
-
15
-
-
33745149291
-
P53 regulates mitochondrial respiration
-
S. Matoba, J.G. Kang, W.D. Patino, A. Wragg, M. Boehm, and O. Gavrilova p53 regulates mitochondrial respiration Science 312 2006 1650 1653
-
(2006)
Science
, vol.312
, pp. 1650-1653
-
-
Matoba, S.1
Kang, J.G.2
Patino, W.D.3
Wragg, A.4
Boehm, M.5
Gavrilova, O.6
-
16
-
-
84855878565
-
P53 negatively regulates transcription of the pyruvate dehydrogenase kinase Pdk2
-
T. Contractor, and C.R. Harris p53 negatively regulates transcription of the pyruvate dehydrogenase kinase Pdk2 Cancer Research 72 2012 560 567
-
(2012)
Cancer Research
, vol.72
, pp. 560-567
-
-
Contractor, T.1
Harris, C.R.2
-
17
-
-
0033257077
-
Identification of seven genes regulated by wild-type p53 in a colon cancer cell line carrying a well-controlled wild-type p53 expression system
-
S. Okamura, C.C. Ng, K. Koyama, Y. Takei, H. Arakawa, and M. Monden Identification of seven genes regulated by wild-type p53 in a colon cancer cell line carrying a well-controlled wild-type p53 expression system Oncology Research 11 1999 281 285
-
(1999)
Oncology Research
, vol.11
, pp. 281-285
-
-
Okamura, S.1
Ng, C.C.2
Koyama, K.3
Takei, Y.4
Arakawa, H.5
Monden, M.6
-
18
-
-
10644244369
-
AIF deficiency compromises oxidative phosphorylation
-
N. Vahsen, C. Cande, J.J. Briere, P. Benit, N. Joza, and N. Larochette AIF deficiency compromises oxidative phosphorylation The EMBO Journal 23 2004 4679 4689
-
(2004)
The EMBO Journal
, vol.23
, pp. 4679-4689
-
-
Vahsen, N.1
Cande, C.2
Briere, J.J.3
Benit, P.4
Joza, N.5
Larochette, N.6
-
19
-
-
84873678601
-
Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence
-
P. Jiang, W. Du, A. Mancuso, K.E. Wellen, and X. Yang Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence Nature 493 2013 689 693
-
(2013)
Nature
, vol.493
, pp. 689-693
-
-
Jiang, P.1
Du, W.2
Mancuso, A.3
Wellen, K.E.4
Yang, X.5
-
20
-
-
77952212178
-
Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function
-
W. Hu, C. Zhang, R. Wu, Y. Sun, A. Levine, and Z. Feng Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function Proceedings of the National Academy of Sciences of the United States of America 107 2010 7455 7460
-
(2010)
Proceedings of the National Academy of Sciences of the United States of America
, vol.107
, pp. 7455-7460
-
-
Hu, W.1
Zhang, C.2
Wu, R.3
Sun, Y.4
Levine, A.5
Feng, Z.6
-
21
-
-
77952227625
-
Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species
-
S. Suzuki, T. Tanaka, M.V. Poyurovsky, H. Nagano, T. Mayama, and S. Ohkubo Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species Proceedings of the National Academy of Sciences of the United States of America 107 2010 7461 7466
-
(2010)
Proceedings of the National Academy of Sciences of the United States of America
, vol.107
, pp. 7461-7466
-
-
Suzuki, S.1
Tanaka, T.2
Poyurovsky, M.V.3
Nagano, H.4
Mayama, T.5
Ohkubo, S.6
-
22
-
-
84863837081
-
Lipid metabolism in cancer
-
C.R. Santos, and A. Schulze Lipid metabolism in cancer The FEBS Journal 279 2012 2610 2623
-
(2012)
The FEBS Journal
, vol.279
, pp. 2610-2623
-
-
Santos, C.R.1
Schulze, A.2
-
23
-
-
0034715909
-
Sterol regulatory element-binding protein-1 participates in the regulation of fatty acid synthase expression in colorectal neoplasia
-
J.N. Li, M.A. Mahmoud, W.F. Han, M. Ripple, and E.S. Pizer Sterol regulatory element-binding protein-1 participates in the regulation of fatty acid synthase expression in colorectal neoplasia Experimental Cell Research 261 2000 159 165
-
(2000)
Experimental Cell Research
, vol.261
, pp. 159-165
-
-
Li, J.N.1
Mahmoud, M.A.2
Han, W.F.3
Ripple, M.4
Pizer, E.S.5
-
24
-
-
0033814153
-
Selective activation of the fatty acid synthesis pathway in human prostate cancer
-
J.V. Swinnen, F. Vanderhoydonc, A.A. Elgamal, M. Eelen, I. Vercaeren, and S. Joniau Selective activation of the fatty acid synthesis pathway in human prostate cancer International Journal of Cancer. Journal international du cancer 88 2000 176 179
-
(2000)
International Journal of Cancer. Journal International du Cancer
, vol.88
, pp. 176-179
-
-
Swinnen, J.V.1
Vanderhoydonc, F.2
Elgamal, A.A.3
Eelen, M.4
Vercaeren, I.5
Joniau, S.6
-
25
-
-
34548814981
-
Up-regulation of acetyl-CoA carboxylase alpha and fatty acid synthase by human epidermal growth factor receptor 2 at the translational level in breast cancer cells
-
S. Yoon, M.Y. Lee, S.W. Park, J.S. Moon, Y.K. Koh, and Y.H. Ahn Up-regulation of acetyl-CoA carboxylase alpha and fatty acid synthase by human epidermal growth factor receptor 2 at the translational level in breast cancer cells The Journal of Biological Chemistry 282 2007 26122 26131
-
(2007)
The Journal of Biological Chemistry
, vol.282
, pp. 26122-26131
-
-
Yoon, S.1
Lee, M.Y.2
Park, S.W.3
Moon, J.S.4
Koh, Y.K.5
Ahn, Y.H.6
-
26
-
-
34748912615
-
Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis
-
J.A. Menendez, and R. Lupu Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis Nature Reviews. Cancer 7 2007 763 777
-
(2007)
Nature Reviews. Cancer
, vol.7
, pp. 763-777
-
-
Menendez, J.A.1
Lupu, R.2
-
27
-
-
84908672508
-
Inhibition of fatty acid synthase induces pro-survival Akt and ERK signaling in K-Ras-driven cancer cells
-
P. Yellen, and D.A. Foster Inhibition of fatty acid synthase induces pro-survival Akt and ERK signaling in K-Ras-driven cancer cells Cancer Letters 353 2 2014 258 263 10.1016/j.canlet.2014.07.027
-
(2014)
Cancer Letters
, vol.353
, Issue.2
, pp. 258-263
-
-
Yellen, P.1
Foster, D.A.2
-
28
-
-
0038491561
-
P53 Activation in adipocytes of obese mice
-
N. Yahagi, H. Shimano, T. Matsuzaka, Y. Najima, M. Sekiya, and Y. Nakagawa p53 Activation in adipocytes of obese mice The Journal of Biological Chemistry 278 2003 25395 25400
-
(2003)
The Journal of Biological Chemistry
, vol.278
, pp. 25395-25400
-
-
Yahagi, N.1
Shimano, H.2
Matsuzaka, T.3
Najima, Y.4
Sekiya, M.5
Nakagawa, Y.6
-
29
-
-
80555135898
-
ROS-mediated p53 induction of Lpin1 regulates fatty acid oxidation in response to nutritional stress
-
W. Assaily, D.A. Rubinger, K. Wheaton, Y. Lin, W. Ma, and W. Xuan ROS-mediated p53 induction of Lpin1 regulates fatty acid oxidation in response to nutritional stress Molecular Cell 44 2011 491 501
-
(2011)
Molecular Cell
, vol.44
, pp. 491-501
-
-
Assaily, W.1
Rubinger, D.A.2
Wheaton, K.3
Lin, Y.4
Ma, W.5
Xuan, W.6
-
30
-
-
84902131086
-
Ribosomal protein-Mdm2-p53 pathway coordinates nutrient stress with lipid metabolism by regulating MCD and promoting fatty acid oxidation
-
Y. Liu, Y. He, A. Jin, A.P. Tikunov, L. Zhou, and L.A. Tollini Ribosomal protein-Mdm2-p53 pathway coordinates nutrient stress with lipid metabolism by regulating MCD and promoting fatty acid oxidation Proceedings of the National Academy of Sciences of the United States of America 111 2014 E2414 E2422
-
(2014)
Proceedings of the National Academy of Sciences of the United States of America
, vol.111
, pp. 2414-E2422
-
-
Liu, Y.1
He, Y.2
Jin, A.3
Tikunov, A.P.4
Zhou, L.5
Tollini, L.A.6
-
32
-
-
84904609077
-
Sirtuins in stress response: Guardians of the genome
-
L. Bosch-Presegue, and A. Vaquero Sirtuins in stress response: guardians of the genome Oncogene 33 29 2014 3764 3775 10.1038/onc.2013.344
-
(2014)
Oncogene
, vol.33
, Issue.29
, pp. 3764-3775
-
-
Bosch-Presegue, L.1
Vaquero, A.2
-
33
-
-
34547875013
-
NAD+-dependent deacetylation of H4 lysine 16 by class III HDACs
-
A. Vaquero, R. Sternglanz, and D. Reinberg NAD+-dependent deacetylation of H4 lysine 16 by class III HDACs Oncogene 26 2007 5505 5520
-
(2007)
Oncogene
, vol.26
, pp. 5505-5520
-
-
Vaquero, A.1
Sternglanz, R.2
Reinberg, D.3
-
36
-
-
80054771657
-
The role of mammalian sirtuins in the regulation of metabolism, aging, and longevity
-
A. Satoh, L. Stein, and S. Imai The role of mammalian sirtuins in the regulation of metabolism, aging, and longevity Handbook of Experimental Pharmacology 206 2011 125 162
-
(2011)
Handbook of Experimental Pharmacology
, vol.206
, pp. 125-162
-
-
Satoh, A.1
Stein, L.2
Imai, S.3
-
37
-
-
79958041304
-
Fine tuning our cellular factories: Sirtuins in mitochondrial biology
-
L. Zhong, and R. Mostoslavsky Fine tuning our cellular factories: sirtuins in mitochondrial biology Cell Metabolism 13 2011 621 626
-
(2011)
Cell Metabolism
, vol.13
, pp. 621-626
-
-
Zhong, L.1
Mostoslavsky, R.2
-
38
-
-
84858796367
-
A two-way street: Reciprocal regulation of metabolism and signalling
-
K.E. Wellen, and C.B. Thompson A two-way street: reciprocal regulation of metabolism and signalling Nature Reviews. Molecular Cell Biology 13 2012 270 276
-
(2012)
Nature Reviews. Molecular Cell Biology
, vol.13
, pp. 270-276
-
-
Wellen, K.E.1
Thompson, C.B.2
-
40
-
-
79955398591
-
Otto Warburg's contributions to current concepts of cancer metabolism
-
W.H. Koppenol, P.L. Bounds, and C.V. Dang Otto Warburg's contributions to current concepts of cancer metabolism Nature Reviews. Cancer 11 2011 325 337
-
(2011)
Nature Reviews. Cancer
, vol.11
, pp. 325-337
-
-
Koppenol, W.H.1
Bounds, P.L.2
Dang, C.V.3
-
41
-
-
66249108601
-
Understanding the Warburg effect: The metabolic requirements of cell proliferation
-
M.G. Vander Heiden, L.C. Cantley, and C.B. Thompson Understanding the Warburg effect: the metabolic requirements of cell proliferation Science 324 2009 1029 1033
-
(2009)
Science
, vol.324
, pp. 1029-1033
-
-
Vander Heiden, M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
42
-
-
78650208106
-
Metabolism strikes back: Metabolic flux regulates cell signaling
-
C.M. Metallo, and M.G. Vander Heiden Metabolism strikes back: metabolic flux regulates cell signaling Genes & Development 24 2010 2717 2722
-
(2010)
Genes & Development
, vol.24
, pp. 2717-2722
-
-
Metallo, C.M.1
Vander Heiden, M.G.2
-
43
-
-
77949887506
-
Mammalian sirtuins: Biological insights and disease relevance
-
M.C. Haigis, and D.A. Sinclair Mammalian sirtuins: biological insights and disease relevance Annual Review of Pathology 5 2010 253 295
-
(2010)
Annual Review of Pathology
, vol.5
, pp. 253-295
-
-
Haigis, M.C.1
Sinclair, D.A.2
-
44
-
-
38649123072
-
Conserved metabolic regulatory functions of sirtuins
-
B. Schwer, and E. Verdin Conserved metabolic regulatory functions of sirtuins Cell Metabolism 7 2008 104 112
-
(2008)
Cell Metabolism
, vol.7
, pp. 104-112
-
-
Schwer, B.1
Verdin, E.2
-
46
-
-
33746992118
-
Substrate and functional diversity of lysine acetylation revealed by a proteomics survey
-
S.C. Kim, R. Sprung, Y. Chen, Y. Xu, H. Ball, and J. Pei Substrate and functional diversity of lysine acetylation revealed by a proteomics survey Molecular Cell 23 2006 607 618
-
(2006)
Molecular Cell
, vol.23
, pp. 607-618
-
-
Kim, S.C.1
Sprung, R.2
Chen, Y.3
Xu, Y.4
Ball, H.5
Pei, J.6
-
47
-
-
77149148756
-
Regulation of cellular metabolism by protein lysine acetylation
-
S. Zhao, W. Xu, W. Jiang, W. Yu, Y. Lin, and T. Zhang Regulation of cellular metabolism by protein lysine acetylation Science 327 2010 1000 1004
-
(2010)
Science
, vol.327
, pp. 1000-1004
-
-
Zhao, S.1
Xu, W.2
Jiang, W.3
Yu, W.4
Lin, Y.5
Zhang, T.6
-
48
-
-
79959371914
-
Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth
-
L. Lv, D. Li, D. Zhao, R. Lin, Y. Chu, and H. Zhang Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth Molecular Cell 42 2011 719 730
-
(2011)
Molecular Cell
, vol.42
, pp. 719-730
-
-
Lv, L.1
Li, D.2
Zhao, D.3
Lin, R.4
Chu, Y.5
Zhang, H.6
-
49
-
-
79955960768
-
Acetyl-CoA induces cell growth and proliferation by promoting the acetylation of histones at growth genes
-
L. Cai, B.M. Sutter, B. Li, and B.P. Tu Acetyl-CoA induces cell growth and proliferation by promoting the acetylation of histones at growth genes Molecular Cell 42 2011 426 437
-
(2011)
Molecular Cell
, vol.42
, pp. 426-437
-
-
Cai, L.1
Sutter, B.M.2
Li, B.3
Tu, B.P.4
-
50
-
-
0034620591
-
Phosphorylation of recombinant human ATP:citrate lyase by cAMP-dependent protein kinase abolishes homotropic allosteric regulation of the enzyme by citrate and increases the enzyme activity. Allosteric activation of ATP:citrate lyase by phosphorylated sugars
-
I.A. Potapova, M.R. El-Maghrabi, S.V. Doronin, and W.B. Benjamin Phosphorylation of recombinant human ATP:citrate lyase by cAMP-dependent protein kinase abolishes homotropic allosteric regulation of the enzyme by citrate and increases the enzyme activity. Allosteric activation of ATP:citrate lyase by phosphorylated sugars Biochemistry 39 2000 1169 1179
-
(2000)
Biochemistry
, vol.39
, pp. 1169-1179
-
-
Potapova, I.A.1
El-Maghrabi, M.R.2
Doronin, S.V.3
Benjamin, W.B.4
-
51
-
-
0037072780
-
The identification of ATP-citrate lyase as a protein kinase B (Akt) substrate in primary adipocytes
-
D.C. Berwick, I. Hers, K.J. Heesom, S.K. Moule, and J.M. Tavare The identification of ATP-citrate lyase as a protein kinase B (Akt) substrate in primary adipocytes The Journal of Biological Chemistry 277 2002 33895 33900
-
(2002)
The Journal of Biological Chemistry
, vol.277
, pp. 33895-33900
-
-
Berwick, D.C.1
Hers, I.2
Heesom, K.J.3
Moule, S.K.4
Tavare, J.M.5
-
52
-
-
30144446161
-
A new strategy for studying protein kinase B and its three isoforms. Role of protein kinase B in phosphorylating glycogen synthase kinase-3, tuberin, WNK1, and ATP citrate lyase
-
E.M. Sale, C.P. Hodgkinson, N.P. Jones, and G.J. Sale A new strategy for studying protein kinase B and its three isoforms. Role of protein kinase B in phosphorylating glycogen synthase kinase-3, tuberin, WNK1, and ATP citrate lyase Biochemistry 45 2006 213 223
-
(2006)
Biochemistry
, vol.45
, pp. 213-223
-
-
Sale, E.M.1
Hodgkinson, C.P.2
Jones, N.P.3
Sale, G.J.4
-
53
-
-
84890523195
-
SIRT1/PARP1 crosstalk: Connecting DNA damage and metabolism
-
A. Luna, M.I. Aladjem, and K.W. Kohn SIRT1/PARP1 crosstalk: connecting DNA damage and metabolism Genome Integrity 4 2013 6
-
(2013)
Genome Integrity
, vol.4
, pp. 6
-
-
Luna, A.1
Aladjem, M.I.2
Kohn, K.W.3
-
54
-
-
84864667383
-
Regulation of sirtuin function by posttranslational modifications
-
F. Flick, and B. Luscher Regulation of sirtuin function by posttranslational modifications Frontiers in Pharmacology 3 2012 29
-
(2012)
Frontiers in Pharmacology
, vol.3
, pp. 29
-
-
Flick, F.1
Luscher, B.2
-
55
-
-
77949539030
-
JNK1 phosphorylates SIRT1 and promotes its enzymatic activity
-
N. Nasrin, V.K. Kaushik, E. Fortier, D. Wall, K.J. Pearson, and R. de Cabo JNK1 phosphorylates SIRT1 and promotes its enzymatic activity PLoS ONE 4 2009 e8414
-
(2009)
PLoS ONE
, vol.4
, pp. 8414
-
-
Nasrin, N.1
Kaushik, V.K.2
Fortier, E.3
Wall, D.4
Pearson, K.J.5
De Cabo, R.6
-
56
-
-
84865793242
-
AMPK promotes p53 acetylation via phosphorylation and inactivation of SIRT1 in liver cancer cells
-
C.W. Lee, L.L. Wong, E.Y. Tse, H.F. Liu, V.Y. Leong, and J.M. Lee AMPK promotes p53 acetylation via phosphorylation and inactivation of SIRT1 in liver cancer cells Cancer Research 72 2012 4394 4404
-
(2012)
Cancer Research
, vol.72
, pp. 4394-4404
-
-
Lee, C.W.1
Wong, L.L.2
Tse, E.Y.3
Liu, H.F.4
Leong, V.Y.5
Lee, J.M.6
-
57
-
-
84908153882
-
SIRT1 phosphorylation by AMP-activated protein kinase regulates p53 acetylation
-
A.W. Lau, P. Liu, H. Inuzuka, and D. Gao SIRT1 phosphorylation by AMP-activated protein kinase regulates p53 acetylation American Journal of Cancer Research 4 2014 245 255
-
(2014)
American Journal of Cancer Research
, vol.4
, pp. 245-255
-
-
Lau, A.W.1
Liu, P.2
Inuzuka, H.3
Gao, D.4
-
58
-
-
69949138641
-
CK2 is the regulator of SIRT1 substrate-binding affinity, deacetylase activity and cellular response to DNA-damage
-
H. Kang, J.W. Jung, M.K. Kim, and J.H. Chung CK2 is the regulator of SIRT1 substrate-binding affinity, deacetylase activity and cellular response to DNA-damage PLoS ONE 4 2009 e6611
-
(2009)
PLoS ONE
, vol.4
, pp. 6611
-
-
Kang, H.1
Jung, J.W.2
Kim, M.K.3
Chung, J.H.4
-
60
-
-
82455219091
-
Peptide switch is essential for Sirt1 deacetylase activity
-
H. Kang, J.Y. Suh, Y.S. Jung, J.W. Jung, M.K. Kim, and J.H. Chung Peptide switch is essential for Sirt1 deacetylase activity Molecular Cell 44 2011 203 213
-
(2011)
Molecular Cell
, vol.44
, pp. 203-213
-
-
Kang, H.1
Suh, J.Y.2
Jung, Y.S.3
Jung, J.W.4
Kim, M.K.5
Chung, J.H.6
-
61
-
-
58149202185
-
Phosphorylation regulates SIRT1 function
-
T. Sasaki, B. Maier, K.D. Koclega, M. Chruszcz, W. Gluba, and P.T. Stukenberg Phosphorylation regulates SIRT1 function PLoS ONE 3 2008 e4020
-
(2008)
PLoS ONE
, vol.3
, pp. 4020
-
-
Sasaki, T.1
Maier, B.2
Koclega, K.D.3
Chruszcz, M.4
Gluba, W.5
Stukenberg, P.T.6
-
62
-
-
77953292238
-
SIRT1 and p53, effect on cancer, senescence and beyond
-
J. Yi, and J. Luo SIRT1 and p53, effect on cancer, senescence and beyond Biochimica et Biophysica Acta 1804 2010 1684 1689
-
(2010)
Biochimica et Biophysica Acta
, vol.1804
, pp. 1684-1689
-
-
Yi, J.1
Luo, J.2
-
63
-
-
0037093346
-
Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence
-
E. Langley, M. Pearson, M. Faretta, U.M. Bauer, R.A. Frye, and S. Minucci Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence The EMBO Journal 21 2002 2383 2396
-
(2002)
The EMBO Journal
, vol.21
, pp. 2383-2396
-
-
Langley, E.1
Pearson, M.2
Faretta, M.3
Bauer, U.M.4
Frye, R.A.5
Minucci, S.6
-
64
-
-
80053123777
-
Interference between PARPs and SIRT1: A novel approach to healthy ageing
-
C. Canto, and J. Auwerx Interference between PARPs and SIRT1: a novel approach to healthy ageing Aging 3 2011 543 547
-
(2011)
Aging
, vol.3
, pp. 543-547
-
-
Canto, C.1
Auwerx, J.2
-
66
-
-
0141814680
-
Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice
-
H.L. Cheng, R. Mostoslavsky, S. Saito, J.P. Manis, Y. Gu, and P. Patel Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice Proceedings of the National Academy of Sciences of the United States of America 100 2003 10794 10799
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, pp. 10794-10799
-
-
Cheng, H.L.1
Mostoslavsky, R.2
Saito, S.3
Manis, J.P.4
Gu, Y.5
Patel, P.6
-
68
-
-
39749087530
-
SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization
-
M.K. Han, E.K. Song, Y. Guo, X. Ou, C. Mantel, and H.E. Broxmeyer SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization Cell Stem Cell 2 2008 241 251
-
(2008)
Cell Stem Cell
, vol.2
, pp. 241-251
-
-
Han, M.K.1
Song, E.K.2
Guo, Y.3
Ou, X.4
Mantel, C.5
Broxmeyer, H.E.6
-
69
-
-
58849158388
-
How does SIRT1 affect metabolism, senescence and cancer
-
C.L. Brooks, and W. Gu How does SIRT1 affect metabolism, senescence and cancer Nature Reviews. Cancer 9 2009 123 128
-
(2009)
Nature Reviews. Cancer
, vol.9
, pp. 123-128
-
-
Brooks, C.L.1
Gu, W.2
-
72
-
-
34547875773
-
Sirtuins: Critical regulators at the crossroads between cancer and aging
-
L.R. Saunders, and E. Verdin Sirtuins: critical regulators at the crossroads between cancer and aging Oncogene 26 2007 5489 5504
-
(2007)
Oncogene
, vol.26
, pp. 5489-5504
-
-
Saunders, L.R.1
Verdin, E.2
-
73
-
-
84902176868
-
SIRT1 mediates FOXA2 breakdown by deacetylation in a nutrient-dependent manner
-
R. van Gent, C. Di Sanza, N.J. van den Broek, V. Fleskens, A. Veenstra, and G.J. Stout SIRT1 mediates FOXA2 breakdown by deacetylation in a nutrient-dependent manner PLoS ONE 9 2014 e98438
-
(2014)
PLoS ONE
, vol.9
, pp. 98438
-
-
Van Gent, R.1
Di Sanza, C.2
Van Den Broek, N.J.3
Fleskens, V.4
Veenstra, A.5
Stout, G.J.6
-
74
-
-
84896690531
-
Regulation of the mitogen-activated protein kinase kinase (MEK)-1 by NAD-dependent deacetylases
-
F. Yeung, C.S. Ramsey, A.E. Popko-Scibor, D.F. Allison, L.G. Gray, and M. Shin Regulation of the mitogen-activated protein kinase kinase (MEK)-1 by NAD-dependent deacetylases Oncogene 2014 10.1038/onc.2014.39
-
(2014)
Oncogene
-
-
Yeung, F.1
Ramsey, C.S.2
Popko-Scibor, A.E.3
Allison, D.F.4
Gray, L.G.5
Shin, M.6
-
75
-
-
84896901019
-
Sirt2 deacetylase is a novel AKT binding partner critical for AKT activation by insulin
-
G. Ramakrishnan, G. Davaakhuu, L. Kaplun, W.C. Chung, A. Rana, and A. Atfi Sirt2 deacetylase is a novel AKT binding partner critical for AKT activation by insulin The Journal of Biological Chemistry 289 2014 6054 6066
-
(2014)
The Journal of Biological Chemistry
, vol.289
, pp. 6054-6066
-
-
Ramakrishnan, G.1
Davaakhuu, G.2
Kaplun, L.3
Chung, W.C.4
Rana, A.5
Atfi, A.6
-
76
-
-
84920288890
-
High-mobility group box 1 is a novel deacetylation target of Sirtuin1
-
M.M. Rabadi, S. Xavier, R. Vasko, K. Kaur, M.S. Goligorksy, and B.B. Ratliff High-mobility group box 1 is a novel deacetylation target of Sirtuin1 Kidney International 2014 10.1038/ki.2014.217
-
(2014)
Kidney International
-
-
Rabadi, M.M.1
Xavier, S.2
Vasko, R.3
Kaur, K.4
Goligorksy, M.S.5
Ratliff, B.B.6
-
77
-
-
53149144656
-
Interplay among BRCA1, SIRT1, and Survivin during BRCA1-associated tumorigenesis
-
R.H. Wang, Y. Zheng, H.S. Kim, X. Xu, L. Cao, and T. Luhasen Interplay among BRCA1, SIRT1, and Survivin during BRCA1-associated tumorigenesis Molecular Cell 32 2008 11 20
-
(2008)
Molecular Cell
, vol.32
, pp. 11-20
-
-
Wang, R.H.1
Zheng, Y.2
Kim, H.S.3
Xu, X.4
Cao, L.5
Luhasen, T.6
-
78
-
-
84898011296
-
Sorting out functions of sirtuins in cancer
-
M. Roth, and W.Y. Chen Sorting out functions of sirtuins in cancer Oncogene 33 2014 1609 1620
-
(2014)
Oncogene
, vol.33
, pp. 1609-1620
-
-
Roth, M.1
Chen, W.Y.2
-
79
-
-
84903716335
-
Sirtuins: Nodes connecting aging, metabolism and tumorigenesis
-
Y. Yao, Y. Yang, and W.G. Zhu Sirtuins: nodes connecting aging, metabolism and tumorigenesis Current Pharmaceutical Design 20 2014 1614 1624
-
(2014)
Current Pharmaceutical Design
, vol.20
, pp. 1614-1624
-
-
Yao, Y.1
Yang, Y.2
Zhu, W.G.3
-
80
-
-
0035913911
-
Negative control of p53 by Sir2alpha promotes cell survival under stress
-
J. Luo, A.Y. Nikolaev, S. Imai, D. Chen, F. Su, and A. Shiloh Negative control of p53 by Sir2alpha promotes cell survival under stress Cell 107 2001 137 148
-
(2001)
Cell
, vol.107
, pp. 137-148
-
-
Luo, J.1
Nikolaev, A.Y.2
Imai, S.3
Chen, D.4
Su, F.5
Shiloh, A.6
-
81
-
-
0035913903
-
HSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase
-
H. Vaziri, S.K. Dessain, E. Ng Eaton, S.I. Imai, R.A. Frye, and T.K. Pandita hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase Cell 107 2001 149 159
-
(2001)
Cell
, vol.107
, pp. 149-159
-
-
Vaziri, H.1
Dessain, S.K.2
Ng Eaton, E.3
Imai, S.I.4
Frye, R.A.5
Pandita, T.K.6
-
82
-
-
4944245398
-
Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin
-
A. Vaquero, M. Scher, D. Lee, H. Erdjument-Bromage, P. Tempst, and D. Reinberg Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin Molecular Cell 16 2004 93 105
-
(2004)
Molecular Cell
, vol.16
, pp. 93-105
-
-
Vaquero, A.1
Scher, M.2
Lee, D.3
Erdjument-Bromage, H.4
Tempst, P.5
Reinberg, D.6
-
83
-
-
79954467406
-
Stabilization of Suv39H1 by SirT1 is part of oxidative stress response and ensures genome protection
-
L. Bosch-Presegue, H. Raurell-Vila, A. Marazuela-Duque, N. Kane-Goldsmith, A. Valle, and J. Oliver Stabilization of Suv39H1 by SirT1 is part of oxidative stress response and ensures genome protection Molecular Cell 42 2011 210 223
-
(2011)
Molecular Cell
, vol.42
, pp. 210-223
-
-
Bosch-Presegue, L.1
Raurell-Vila, H.2
Marazuela-Duque, A.3
Kane-Goldsmith, N.4
Valle, A.5
Oliver, J.6
-
84
-
-
50849104569
-
Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island
-
H.M. O'Hagan, H.P. Mohammad, and S.B. Baylin Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island PLoS Genetics 4 2008 e1000155
-
(2008)
PLoS Genetics
, vol.4
, pp. 1000155
-
-
O'Hagan, H.M.1
Mohammad, H.P.2
Baylin, S.B.3
-
85
-
-
33645768490
-
Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation
-
K. Pruitt, R.L. Zinn, J.E. Ohm, K.M. McGarvey, S.H. Kang, and D.N. Watkins Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation PLoS Genetics 2 2006 e40
-
(2006)
PLoS Genetics
, vol.2
, pp. 40
-
-
Pruitt, K.1
Zinn, R.L.2
Ohm, J.E.3
McGarvey, K.M.4
Kang, S.H.5
Watkins, D.N.6
-
86
-
-
77955501963
-
SIRT1 regulates UV-induced DNA repair through deacetylating XPA
-
W. Fan, and J. Luo SIRT1 regulates UV-induced DNA repair through deacetylating XPA Molecular Cell 39 2010 247 258
-
(2010)
Molecular Cell
, vol.39
, pp. 247-258
-
-
Fan, W.1
Luo, J.2
-
87
-
-
78651105018
-
Regulation of global genome nucleotide excision repair by SIRT1 through xeroderma pigmentosum C
-
M. Ming, C.R. Shea, X. Guo, X. Li, K. Soltani, and W. Han Regulation of global genome nucleotide excision repair by SIRT1 through xeroderma pigmentosum C Proceedings of the National Academy of Sciences of the United States of America 107 2010 22623 22628
-
(2010)
Proceedings of the National Academy of Sciences of the United States of America
, vol.107
, pp. 22623-22628
-
-
Ming, M.1
Shea, C.R.2
Guo, X.3
Li, X.4
Soltani, K.5
Han, W.6
-
88
-
-
0034690249
-
Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development
-
Y. Gao, D.O. Ferguson, W. Xie, J.P. Manis, J. Sekiguchi, and K.M. Frank Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development Nature 404 2000 897 900
-
(2000)
Nature
, vol.404
, pp. 897-900
-
-
Gao, Y.1
Ferguson, D.O.2
Xie, W.3
Manis, J.P.4
Sekiguchi, J.5
Frank, K.M.6
-
89
-
-
33847647624
-
SIRT1 promotes DNA repair activity and deacetylation of Ku70
-
J. Jeong, K. Juhn, H. Lee, S.H. Kim, B.H. Min, and K.M. Lee SIRT1 promotes DNA repair activity and deacetylation of Ku70 Experimental & Molecular Medicine 39 2007 8 13
-
(2007)
Experimental & Molecular Medicine
, vol.39
, pp. 8-13
-
-
Jeong, J.1
Juhn, K.2
Lee, H.3
Kim, S.H.4
Min, B.H.5
Lee, K.M.6
-
90
-
-
43149118368
-
Regulation of WRN protein cellular localization and enzymatic activities by SIRT1-mediated deacetylation
-
K. Li, A. Casta, R. Wang, E. Lozada, W. Fan, and S. Kane Regulation of WRN protein cellular localization and enzymatic activities by SIRT1-mediated deacetylation The Journal of Biological Chemistry 283 2008 7590 7598
-
(2008)
The Journal of Biological Chemistry
, vol.283
, pp. 7590-7598
-
-
Li, K.1
Casta, A.2
Wang, R.3
Lozada, E.4
Fan, W.5
Kane, S.6
-
91
-
-
37549016377
-
A functional link between SIRT1 deacetylase and NBS1 in DNA damage response
-
Z. Yuan, and E. Seto A functional link between SIRT1 deacetylase and NBS1 in DNA damage response Cell Cycle 6 2007 2869 2871
-
(2007)
Cell Cycle
, vol.6
, pp. 2869-2871
-
-
Yuan, Z.1
Seto, E.2
-
92
-
-
34250897968
-
SIRT1 regulates the function of the Nijmegen breakage syndrome protein
-
Z. Yuan, X. Zhang, N. Sengupta, W.S. Lane, and E. Seto SIRT1 regulates the function of the Nijmegen breakage syndrome protein Molecular Cell 27 2007 149 162
-
(2007)
Molecular Cell
, vol.27
, pp. 149-162
-
-
Yuan, Z.1
Zhang, X.2
Sengupta, N.3
Lane, W.S.4
Seto, E.5
-
93
-
-
53149137486
-
Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice
-
R.H. Wang, K. Sengupta, C. Li, H.S. Kim, L. Cao, and C. Xiao Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice Cancer Cell 14 2008 312 323
-
(2008)
Cancer Cell
, vol.14
, pp. 312-323
-
-
Wang, R.H.1
Sengupta, K.2
Li, C.3
Kim, H.S.4
Cao, L.5
Xiao, C.6
-
94
-
-
56749156405
-
SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging
-
P. Oberdoerffer, S. Michan, M. McVay, R. Mostoslavsky, J. Vann, and S.K. Park SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging Cell 135 2008 907 918
-
(2008)
Cell
, vol.135
, pp. 907-918
-
-
Oberdoerffer, P.1
Michan, S.2
McVay, M.3
Mostoslavsky, R.4
Vann, J.5
Park, S.K.6
-
95
-
-
37549014206
-
The mammalian ortholog of Drosophila MOF that acetylates histone H4 lysine 16 is essential for embryogenesis and oncogenesis
-
A. Gupta, T.G. Guerin-Peyrou, G.G. Sharma, C. Park, M. Agarwal, and R.K. Ganju The mammalian ortholog of Drosophila MOF that acetylates histone H4 lysine 16 is essential for embryogenesis and oncogenesis Molecular and Cellular Biology 28 2008 397 409
-
(2008)
Molecular and Cellular Biology
, vol.28
, pp. 397-409
-
-
Gupta, A.1
Guerin-Peyrou, T.G.2
Sharma, G.G.3
Park, C.4
Agarwal, M.5
Ganju, R.K.6
-
96
-
-
34547913733
-
Males absent on the first (MOF): From flies to humans
-
S. Rea, G. Xouri, and A. Akhtar Males absent on the first (MOF): from flies to humans Oncogene 26 2007 5385 5394
-
(2007)
Oncogene
, vol.26
, pp. 5385-5394
-
-
Rea, S.1
Xouri, G.2
Akhtar, A.3
-
97
-
-
0034682736
-
Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis
-
T. Ikura, V.V. Ogryzko, M. Grigoriev, R. Groisman, J. Wang, and M. Horikoshi Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis Cell 102 2000 463 473
-
(2000)
Cell
, vol.102
, pp. 463-473
-
-
Ikura, T.1
Ogryzko, V.V.2
Grigoriev, M.3
Groisman, R.4
Wang, J.5
Horikoshi, M.6
-
98
-
-
84864020743
-
SIRT1 negatively regulates the activities, functions, and protein levels of hMOF and TIP60
-
L. Peng, H. Ling, Z. Yuan, B. Fang, G. Bloom, and K. Fukasawa SIRT1 negatively regulates the activities, functions, and protein levels of hMOF and TIP60 Molecular and Cellular Biology 32 2012 2823 2836
-
(2012)
Molecular and Cellular Biology
, vol.32
, pp. 2823-2836
-
-
Peng, L.1
Ling, H.2
Yuan, Z.3
Fang, B.4
Bloom, G.5
Fukasawa, K.6
-
99
-
-
24944516931
-
A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM
-
Y. Sun, X. Jiang, S. Chen, N. Fernandes, and B.D. Price A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM Proceedings of the National Academy of Sciences of the United States of America 102 2005 13182 13187
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, pp. 13182-13187
-
-
Sun, Y.1
Jiang, X.2
Chen, S.3
Fernandes, N.4
Price, B.D.5
-
100
-
-
0037385609
-
Ku70 suppresses the apoptotic translocation of Bax to mitochondria
-
M. Sawada, W. Sun, P. Hayes, K. Leskov, D.A. Boothman, and S. Matsuyama Ku70 suppresses the apoptotic translocation of Bax to mitochondria Nature Cell Biology 5 2003 320 329
-
(2003)
Nature Cell Biology
, vol.5
, pp. 320-329
-
-
Sawada, M.1
Sun, W.2
Hayes, P.3
Leskov, K.4
Boothman, D.A.5
Matsuyama, S.6
-
101
-
-
12144286529
-
Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis
-
H.Y. Cohen, S. Lavu, K.J. Bitterman, B. Hekking, T.A. Imahiyerobo, and C. Miller Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis Molecular Cell 13 2004 627 638
-
(2004)
Molecular Cell
, vol.13
, pp. 627-638
-
-
Cohen, H.Y.1
Lavu, S.2
Bitterman, K.J.3
Hekking, B.4
Imahiyerobo, T.A.5
Miller, C.6
-
102
-
-
3142740860
-
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
-
H.Y. Cohen, C. Miller, K.J. Bitterman, N.R. Wall, B. Hekking, and B. Kessler Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase Science 305 2004 390 392
-
(2004)
Science
, vol.305
, pp. 390-392
-
-
Cohen, H.Y.1
Miller, C.2
Bitterman, K.J.3
Wall, N.R.4
Hekking, B.5
Kessler, B.6
-
103
-
-
0037359584
-
The absence of SIR2alpha protein has no effect on global gene silencing in mouse embryonic stem cells
-
M.W. McBurney, X. Yang, K. Jardine, M. Bieman, J. Th'ng, and M. Lemieux The absence of SIR2alpha protein has no effect on global gene silencing in mouse embryonic stem cells Molecular Cancer Research: MCR 1 2003 402 409
-
(2003)
Molecular Cancer Research: MCR
, vol.1
, pp. 402-409
-
-
McBurney, M.W.1
Yang, X.2
Jardine, K.3
Bieman, M.4
Th'Ng, J.5
Lemieux, M.6
-
104
-
-
0037207475
-
The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis
-
M.W. McBurney, X. Yang, K. Jardine, M. Hixon, K. Boekelheide, and J.R. Webb The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis Molecular and Cellular Biology 23 2003 38 54
-
(2003)
Molecular and Cellular Biology
, vol.23
, pp. 38-54
-
-
McBurney, M.W.1
Yang, X.2
Jardine, K.3
Hixon, M.4
Boekelheide, K.5
Webb, J.R.6
-
105
-
-
84861973567
-
Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence
-
T. Li, N. Kon, L. Jiang, M. Tan, T. Ludwig, and Y. Zhao Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence Cell 149 2012 1269 1283
-
(2012)
Cell
, vol.149
, pp. 1269-1283
-
-
Li, T.1
Kon, N.2
Jiang, L.3
Tan, M.4
Ludwig, T.5
Zhao, Y.6
-
106
-
-
84867094874
-
TAp63 is a master transcriptional regulator of lipid and glucose metabolism
-
X. Su, Y.J. Gi, D. Chakravarti, I.L. Chan, A. Zhang, and X. Xia TAp63 is a master transcriptional regulator of lipid and glucose metabolism Cell Metabolism 16 2012 511 525
-
(2012)
Cell Metabolism
, vol.16
, pp. 511-525
-
-
Su, X.1
Gi, Y.J.2
Chakravarti, D.3
Chan, I.L.4
Zhang, A.5
Xia, X.6
-
107
-
-
84866497949
-
TAp73 depletion accelerates aging through metabolic dysregulation
-
A. Rufini, M.V. Niklison-Chirou, S. Inoue, R. Tomasini, I.S. Harris, and A. Marino TAp73 depletion accelerates aging through metabolic dysregulation Genes & Development 26 2012 2009 2014
-
(2012)
Genes & Development
, vol.26
, pp. 2009-2014
-
-
Rufini, A.1
Niklison-Chirou, M.V.2
Inoue, S.3
Tomasini, R.4
Harris, I.S.5
Marino, A.6
-
108
-
-
84887430076
-
Metabolic regulation by p53 family members
-
C.R. Berkers, O.D. Maddocks, E.C. Cheung, I. Mor, and K.H. Vousden Metabolic regulation by p53 family members Cell Metabolism 18 2013 617 633
-
(2013)
Cell Metabolism
, vol.18
, pp. 617-633
-
-
Berkers, C.R.1
Maddocks, O.D.2
Cheung, E.C.3
Mor, I.4
Vousden, K.H.5
-
109
-
-
84885699761
-
Identification of cisplatin-regulated metabolic pathways in pluripotent stem cells
-
L. von Stechow, A. Ruiz-Aracama, B. van de Water, A. Peijnenburg, E. Danen, and A. Lommen Identification of cisplatin-regulated metabolic pathways in pluripotent stem cells PLoS ONE 8 2013 e76476
-
(2013)
PLoS ONE
, vol.8
, pp. 76476
-
-
Von Stechow, L.1
Ruiz-Aracama, A.2
Van De Water, B.3
Peijnenburg, A.4
Danen, E.5
Lommen, A.6
-
110
-
-
80053555789
-
More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance
-
J. Lukas, C. Lukas, and J. Bartek More than just a focus: the chromatin response to DNA damage and its role in genome integrity maintenance Nature Cell Biology 13 2011 1161 1169
-
(2011)
Nature Cell Biology
, vol.13
, pp. 1161-1169
-
-
Lukas, J.1
Lukas, C.2
Bartek, J.3
-
111
-
-
84861875303
-
Chromatin dynamics in DNA double-strand break repair
-
L. Shi, and P. Oberdoerffer Chromatin dynamics in DNA double-strand break repair Biochimica et Biophysica Acta 1819 2012 811 819
-
(2012)
Biochimica et Biophysica Acta
, vol.1819
, pp. 811-819
-
-
Shi, L.1
Oberdoerffer, P.2
-
112
-
-
84863001577
-
Prime, repair, restore: The active role of chromatin in the DNA damage response
-
G. Soria, S.E. Polo, and G. Almouzni Prime, repair, restore: the active role of chromatin in the DNA damage response Molecular Cell 46 2012 722 734
-
(2012)
Molecular Cell
, vol.46
, pp. 722-734
-
-
Soria, G.1
Polo, S.E.2
Almouzni, G.3
-
113
-
-
84875212373
-
Targeting DNA damage response: Threshold, chromatin landscape and beyond
-
S. Gonfloni Targeting DNA damage response: threshold, chromatin landscape and beyond Pharmacology & Therapeutics 138 2013 46 52
-
(2013)
Pharmacology & Therapeutics
, vol.138
, pp. 46-52
-
-
Gonfloni, S.1
-
114
-
-
84878918708
-
The chromatin response to DNA breaks: Leaving a mark on genome integrity
-
G. Smeenk, and H. van Attikum The chromatin response to DNA breaks: leaving a mark on genome integrity Annual Review of Biochemistry 82 2013 55 80
-
(2013)
Annual Review of Biochemistry
, vol.82
, pp. 55-80
-
-
Smeenk, G.1
Van Attikum, H.2
-
115
-
-
84886056389
-
Metabolic modulation of chromatin: Implications for DNA repair and genomic integrity
-
J. Liu, J. Kim, and P. Oberdoerffer Metabolic modulation of chromatin: implications for DNA repair and genomic integrity Frontiers in Genetics 4 2013 182
-
(2013)
Frontiers in Genetics
, vol.4
, pp. 182
-
-
Liu, J.1
Kim, J.2
Oberdoerffer, P.3
-
116
-
-
65549120715
-
Modes of p53 regulation
-
J.P. Kruse, and W. Gu Modes of p53 regulation Cell 137 2009 609 622
-
(2009)
Cell
, vol.137
, pp. 609-622
-
-
Kruse, J.P.1
Gu, W.2
-
117
-
-
84905108850
-
The cytoplasmic side of p53's oncosuppressive activities
-
A. Comel, G. Sorrentino, V. Capaci, and G. Del Sal The cytoplasmic side of p53's oncosuppressive activities FEBS Letters 588 16 2014 2600 2609 10.1016/j.febslet.2014.04.015
-
(2014)
FEBS Letters
, vol.588
, Issue.16
, pp. 2600-2609
-
-
Comel, A.1
Sorrentino, G.2
Capaci, V.3
Del Sal, G.4
|