-
1
-
-
77949874234
-
Histone variants - ancient wrap artists of the epigenome
-
Talbert P.B., Henikoff S. Histone variants - ancient wrap artists of the epigenome. Nat. Rev. Mol. Cell Biol. 2010, 11:264-275.
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 264-275
-
-
Talbert, P.B.1
Henikoff, S.2
-
2
-
-
77956153243
-
The language of histone crosstalk
-
Lee J.S., Smith E., Shilatifard A. The language of histone crosstalk. Cell 2010, 142:682-685.
-
(2010)
Cell
, vol.142
, pp. 682-685
-
-
Lee, J.S.1
Smith, E.2
Shilatifard, A.3
-
3
-
-
78649336706
-
The DNA damage response: making it safe to play with knives
-
Ciccia A., Elledge S.J. The DNA damage response: making it safe to play with knives. Mol. Cell 2010, 40:179-204.
-
(2010)
Mol. Cell
, vol.40
, pp. 179-204
-
-
Ciccia, A.1
Elledge, S.J.2
-
4
-
-
79952235291
-
Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications
-
Polo S.E., Jackson S.P. Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications. Genes Dev. 2011, 25:409-433.
-
(2011)
Genes Dev.
, vol.25
, pp. 409-433
-
-
Polo, S.E.1
Jackson, S.P.2
-
5
-
-
62849083222
-
The emerging role of nuclear architecture in DNA repair and genome maintenance
-
Misteli T., Soutoglou E. The emerging role of nuclear architecture in DNA repair and genome maintenance. Nat. Rev. Mol. Cell Biol. 2009, 10:243-254.
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 243-254
-
-
Misteli, T.1
Soutoglou, E.2
-
6
-
-
78649450619
-
Assembly and function of DNA double-strand break repair foci in mammalian cells
-
Bekker-Jensen S., Mailand N. Assembly and function of DNA double-strand break repair foci in mammalian cells. DNA Repair (Amst) 2010, 9:1219-1228.
-
(2010)
DNA Repair (Amst)
, vol.9
, pp. 1219-1228
-
-
Bekker-Jensen, S.1
Mailand, N.2
-
7
-
-
0032861343
-
Megabase chromatin domains involved in DNA double-strand breaks in vivo
-
Rogakou E.P., Boon C., Redon C., Bonner W.M. Megabase chromatin domains involved in DNA double-strand breaks in vivo. J. Cell Biol. 1999, 146:905-916.
-
(1999)
J. Cell Biol.
, vol.146
, pp. 905-916
-
-
Rogakou, E.P.1
Boon, C.2
Redon, C.3
Bonner, W.M.4
-
8
-
-
33847076248
-
Chromatin challenges during DNA replication and repair
-
Groth A., Rocha W., Verreault A., Almouzni G. Chromatin challenges during DNA replication and repair. Cell 2007, 128:721-733.
-
(2007)
Cell
, vol.128
, pp. 721-733
-
-
Groth, A.1
Rocha, W.2
Verreault, A.3
Almouzni, G.4
-
9
-
-
80052714988
-
Histone tails: directing the chromatin response to DNA damage
-
Greenberg R.A. Histone tails: directing the chromatin response to DNA damage. FEBS Lett. 2011, 585:2883-2890.
-
(2011)
FEBS Lett.
, vol.585
, pp. 2883-2890
-
-
Greenberg, R.A.1
-
10
-
-
0018125018
-
Nucleosome rearrangement in human chromatin during UV-induced DNA-repair synthesis
-
Smerdon M.J., Lieberman M.W. Nucleosome rearrangement in human chromatin during UV-induced DNA-repair synthesis. Proc. Natl. Acad. Sci. U. S. A. 1978, 75:4238-4241.
-
(1978)
Proc. Natl. Acad. Sci. U. S. A.
, vol.75
, pp. 4238-4241
-
-
Smerdon, M.J.1
Lieberman, M.W.2
-
11
-
-
33644905252
-
Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks
-
Kruhlak M.J., Celeste A., Dellaire G., Fernandez-Capetillo O., Muller W.G., McNally J.G., Bazett-Jones D.P., Nussenzweig A. Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks. J. Cell Biol. 2006, 172:823-834.
-
(2006)
J. Cell Biol.
, vol.172
, pp. 823-834
-
-
Kruhlak, M.J.1
Celeste, A.2
Dellaire, G.3
Fernandez-Capetillo, O.4
Muller, W.G.5
McNally, J.G.6
Bazett-Jones, D.P.7
Nussenzweig, A.8
-
12
-
-
0037472924
-
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
-
Bakkenist C.J., Kastan M.B. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 2003, 421:499-506.
-
(2003)
Nature
, vol.421
, pp. 499-506
-
-
Bakkenist, C.J.1
Kastan, M.B.2
-
13
-
-
58149328408
-
Activation of ATM depends on chromatin interactions occurring before induction of DNA damage
-
Kim Y.C., Gerlitz G., Furusawa T., Catez F., Nussenzweig A., Oh K.S., Kraemer K.H., Shiloh Y., Bustin M. Activation of ATM depends on chromatin interactions occurring before induction of DNA damage. Nat. Cell Biol. 2009, 11:92-96.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 92-96
-
-
Kim, Y.C.1
Gerlitz, G.2
Furusawa, T.3
Catez, F.4
Nussenzweig, A.5
Oh, K.S.6
Kraemer, K.H.7
Shiloh, Y.8
Bustin, M.9
-
14
-
-
67650725820
-
The biology of chromatin remodeling complexes
-
Clapier C.R., Cairns B.R. The biology of chromatin remodeling complexes. Annu. Rev. Biochem. 2009, 78:273-304.
-
(2009)
Annu. Rev. Biochem.
, vol.78
, pp. 273-304
-
-
Clapier, C.R.1
Cairns, B.R.2
-
15
-
-
67349147423
-
Chromatin remodelling beyond transcription: the INO80 and SWR1 complexes
-
Morrison A.J., Shen X. Chromatin remodelling beyond transcription: the INO80 and SWR1 complexes. Nat. Rev. Mol. Cell Biol. 2009, 10:373-384.
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 373-384
-
-
Morrison, A.J.1
Shen, X.2
-
16
-
-
77956387556
-
The NuRD chromatin-remodeling complex regulates signaling and repair of DNA damage
-
Smeenk G., Wiegant W.W., Vrolijk H., Solari A.P., Pastink A., van Attikum H. The NuRD chromatin-remodeling complex regulates signaling and repair of DNA damage. J. Cell Biol. 2010, 190:741-749.
-
(2010)
J. Cell Biol.
, vol.190
, pp. 741-749
-
-
Smeenk, G.1
Wiegant, W.W.2
Vrolijk, H.3
Solari, A.P.4
Pastink, A.5
van Attikum, H.6
-
17
-
-
77956870690
-
Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4
-
Polo S.E., Kaidi A., Baskcomb L., Galanty Y., Jackson S.P. Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4. EMBO J. 2010, 29:3130-3139.
-
(2010)
EMBO J.
, vol.29
, pp. 3130-3139
-
-
Polo, S.E.1
Kaidi, A.2
Baskcomb, L.3
Galanty, Y.4
Jackson, S.P.5
-
18
-
-
77956379478
-
The chromatin-remodeling factor CHD4 coordinates signaling and repair after DNA damage
-
Larsen D.H., Poinsignon C., Gudjonsson T., Dinant C., Payne M.R., Hari F.J., Danielsen J.M., Menard P., Sand J.C., Stucki M., Lukas C., Bartek J., Andersen J.S., Lukas J. The chromatin-remodeling factor CHD4 coordinates signaling and repair after DNA damage. J. Cell Biol. 2010, 190:731-740.
-
(2010)
J. Cell Biol.
, vol.190
, pp. 731-740
-
-
Larsen, D.H.1
Poinsignon, C.2
Gudjonsson, T.3
Dinant, C.4
Payne, M.R.5
Hari, F.J.6
Danielsen, J.M.7
Menard, P.8
Sand, J.C.9
Stucki, M.10
Lukas, C.11
Bartek, J.12
Andersen, J.S.13
Lukas, J.14
-
19
-
-
79952270884
-
HDACs link the DNA damage response, processing of double-strand breaks and autophagy
-
Robert T., Vanoli F., Chiolo I., Shubassi G., Bernstein K.A., Rothstein R., Botrugno O.A., Parazzoli D., Oldani A., Minucci S., Foiani M. HDACs link the DNA damage response, processing of double-strand breaks and autophagy. Nature 2011, 471:74-79.
-
(2011)
Nature
, vol.471
, pp. 74-79
-
-
Robert, T.1
Vanoli, F.2
Chiolo, I.3
Shubassi, G.4
Bernstein, K.A.5
Rothstein, R.6
Botrugno, O.A.7
Parazzoli, D.8
Oldani, A.9
Minucci, S.10
Foiani, M.11
-
20
-
-
77956341931
-
Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining
-
Miller K.M., Tjeertes J.V., Coates J., Legube G., Polo S.E., Britton S., Jackson S.P. Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining. Nat. Struct. Mol. Biol. 2010, 17:1144-1151.
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 1144-1151
-
-
Miller, K.M.1
Tjeertes, J.V.2
Coates, J.3
Legube, G.4
Polo, S.E.5
Britton, S.6
Jackson, S.P.7
-
21
-
-
78649349810
-
A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage
-
Chou D.M., Adamson B., Dephoure N.E., Tan X., Nottke A.C., Hurov K.E., Gygi S.P., Colaiacovo M.P., Elledge S.J. A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage. Proc. Natl. Acad. Sci. U. S. A. 2010, 107:18475-18480.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 18475-18480
-
-
Chou, D.M.1
Adamson, B.2
Dephoure, N.E.3
Tan, X.4
Nottke, A.C.5
Hurov, K.E.6
Gygi, S.P.7
Colaiacovo, M.P.8
Elledge, S.J.9
-
22
-
-
79960844248
-
Cancer biology and NuRD: a multifaceted chromatin remodelling complex
-
Lai A.Y., Wade P.A. Cancer biology and NuRD: a multifaceted chromatin remodelling complex. Nat. Rev. Cancer 2011, 11:588-596.
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 588-596
-
-
Lai, A.Y.1
Wade, P.A.2
-
23
-
-
78649349810
-
A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage
-
Chou D.M., Adamson B., Dephoure N.E., Tan X., Nottke A.C., Hurov K.E., Gygi S.P., Colaiacovo M.P., Elledge S.J. A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage. Proc Natl Acad Sci U S A 2010, 107:18475-18480.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 18475-18480
-
-
Chou, D.M.1
Adamson, B.2
Dephoure, N.E.3
Tan, X.4
Nottke, A.C.5
Hurov, K.E.6
Gygi, S.P.7
Colaiacovo, M.P.8
Elledge, S.J.9
-
24
-
-
77953995002
-
Covalent histone modifications - miswritten, misinterpreted and mis-erased in human cancers
-
Chi P., Allis C.D., Wang G.G. Covalent histone modifications - miswritten, misinterpreted and mis-erased in human cancers. Nat. Rev. Cancer 2010, 10:457-469.
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 457-469
-
-
Chi, P.1
Allis, C.D.2
Wang, G.G.3
-
25
-
-
30344444484
-
Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks
-
Murr R., Loizou J.I., Yang Y.G., Cuenin C., Li H., Wang Z.Q., Herceg Z. Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks. Nat. Cell Biol. 2006, 8:91-99.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 91-99
-
-
Murr, R.1
Loizou, J.I.2
Yang, Y.G.3
Cuenin, C.4
Li, H.5
Wang, Z.Q.6
Herceg, Z.7
-
26
-
-
70449518412
-
Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60
-
Sun Y., Jiang X., Xu Y., Ayrapetov M.K., Moreau L.A., Whetstine J.R., Price B.D. Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60. Nat. Cell Biol. 2009, 11:1376-1382.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 1376-1382
-
-
Sun, Y.1
Jiang, X.2
Xu, Y.3
Ayrapetov, M.K.4
Moreau, L.A.5
Whetstine, J.R.6
Price, B.D.7
-
27
-
-
22444448143
-
A role for cell-cycle-regulated histone H3 lysine 56 acetylation in the DNA damage response
-
Masumoto H., Hawke D., Kobayashi R., Verreault A. A role for cell-cycle-regulated histone H3 lysine 56 acetylation in the DNA damage response. Nature 2005, 436:294-298.
-
(2005)
Nature
, vol.436
, pp. 294-298
-
-
Masumoto, H.1
Hawke, D.2
Kobayashi, R.3
Verreault, A.4
-
28
-
-
47549105301
-
Acetylated lysine 56 on histone H3 drives chromatin assembly after repair and signals for the completion of repair
-
Chen C.C., Carson J.J., Feser J., Tamburini B., Zabaronick S., Linger J., Tyler J.K. Acetylated lysine 56 on histone H3 drives chromatin assembly after repair and signals for the completion of repair. Cell 2008, 134:231-243.
-
(2008)
Cell
, vol.134
, pp. 231-243
-
-
Chen, C.C.1
Carson, J.J.2
Feser, J.3
Tamburini, B.4
Zabaronick, S.5
Linger, J.6
Tyler, J.K.7
-
29
-
-
65549113750
-
CBP/p300-mediated acetylation of histone H3 on lysine 56
-
Das C., Lucia M.S., Hansen K.C., Tyler J.K. CBP/p300-mediated acetylation of histone H3 on lysine 56. Nature 2009, 459:113-117.
-
(2009)
Nature
, vol.459
, pp. 113-117
-
-
Das, C.1
Lucia, M.S.2
Hansen, K.C.3
Tyler, J.K.4
-
30
-
-
69249221533
-
Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6
-
Michishita E., McCord R.A., Boxer L.D., Barber M.F., Hong T., Gozani O., Chua K.F. Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6. Cell Cycle 2009, 8:2664-2666.
-
(2009)
Cell Cycle
, vol.8
, pp. 2664-2666
-
-
Michishita, E.1
McCord, R.A.2
Boxer, L.D.3
Barber, M.F.4
Hong, T.5
Gozani, O.6
Chua, K.F.7
-
31
-
-
69249229772
-
The sirtuin SIRT6 deacetylates H3 K56Ac in vivo to promote genomic stability
-
Yang B., Zwaans B.M., Eckersdorff M., Lombard D.B. The sirtuin SIRT6 deacetylates H3 K56Ac in vivo to promote genomic stability. Cell Cycle 2009, 8:2662-2663.
-
(2009)
Cell Cycle
, vol.8
, pp. 2662-2663
-
-
Yang, B.1
Zwaans, B.M.2
Eckersdorff, M.3
Lombard, D.B.4
-
32
-
-
59049091728
-
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins
-
Doil C., Mailand N., Bekker-Jensen S., Menard P., Larsen D.H., Pepperkok R., Ellenberg J., Panier S., Durocher D., Bartek J., Lukas J., Lukas C. RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins. Cell 2009, 136:435-446.
-
(2009)
Cell
, vol.136
, pp. 435-446
-
-
Doil, C.1
Mailand, N.2
Bekker-Jensen, S.3
Menard, P.4
Larsen, D.H.5
Pepperkok, R.6
Ellenberg, J.7
Panier, S.8
Durocher, D.9
Bartek, J.10
Lukas, J.11
Lukas, C.12
-
33
-
-
36249031962
-
RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly
-
Huen M.S., Grant R., Manke I., Minn K., Yu X., Yaffe M.B., Chen J. RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly. Cell 2007, 131:901-914.
-
(2007)
Cell
, vol.131
, pp. 901-914
-
-
Huen, M.S.1
Grant, R.2
Manke, I.3
Minn, K.4
Yu, X.5
Yaffe, M.B.6
Chen, J.7
-
34
-
-
36248966246
-
RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins
-
Mailand N., Bekker-Jensen S., Faustrup H., Melander F., Bartek J., Lukas C., Lukas J. RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins. Cell 2007, 131:887-900.
-
(2007)
Cell
, vol.131
, pp. 887-900
-
-
Mailand, N.1
Bekker-Jensen, S.2
Faustrup, H.3
Melander, F.4
Bartek, J.5
Lukas, C.6
Lukas, J.7
-
35
-
-
59049103900
-
The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage
-
Stewart G.S., Panier S., Townsend K., Al-Hakim A.K., Kolas N.K., Miller E.S., Nakada S., Ylanko J., Olivarius S., Mendez M., Oldreive C., Wildenhain J., Tagliaferro A., Pelletier L., Taubenheim N., Durandy A., Byrd P.J., Stankovic T., Taylor A.M., Durocher D. The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage. Cell 2009, 136:420-434.
-
(2009)
Cell
, vol.136
, pp. 420-434
-
-
Stewart, G.S.1
Panier, S.2
Townsend, K.3
Al-Hakim, A.K.4
Kolas, N.K.5
Miller, E.S.6
Nakada, S.7
Ylanko, J.8
Olivarius, S.9
Mendez, M.10
Oldreive, C.11
Wildenhain, J.12
Tagliaferro, A.13
Pelletier, L.14
Taubenheim, N.15
Durandy, A.16
Byrd, P.J.17
Stankovic, T.18
Taylor, A.M.19
Durocher, D.20
more..
-
36
-
-
34249950879
-
Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response
-
Kim H., Chen J., Yu X. Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response. Science 2007, 316:1202-1205.
-
(2007)
Science
, vol.316
, pp. 1202-1205
-
-
Kim, H.1
Chen, J.2
Yu, X.3
-
37
-
-
34249949779
-
RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites
-
Sobhian B., Shao G., Lilli D.R., Culhane A.C., Moreau L.A., Xia B., Livingston D.M., Greenberg R.A. RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites. Science 2007, 316:1198-1202.
-
(2007)
Science
, vol.316
, pp. 1198-1202
-
-
Sobhian, B.1
Shao, G.2
Lilli, D.R.3
Culhane, A.C.4
Moreau, L.A.5
Xia, B.6
Livingston, D.M.7
Greenberg, R.A.8
-
38
-
-
34249946686
-
Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response
-
Wang B., Matsuoka S., Ballif B.A., Zhang D., Smogorzewska A., Gygi S.P., Elledge S.J. Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response. Science 2007, 316:1194-1198.
-
(2007)
Science
, vol.316
, pp. 1194-1198
-
-
Wang, B.1
Matsuoka, S.2
Ballif, B.A.3
Zhang, D.4
Smogorzewska, A.5
Gygi, S.P.6
Elledge, S.J.7
-
39
-
-
79951974992
-
Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks
-
Moyal L., Lerenthal Y., Gana-Weisz M., Mass G., So S., Wang S.Y., Eppink B., Chung Y.M., Shalev G., Shema E., Shkedy D., Smorodinsky N.I., van Vliet N., Kuster B., Mann M., Ciechanover A., Dahm-Daphi J., Kanaar R., Hu M.C., Chen D.J., Oren M., Shiloh Y. Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks. Mol. Cell 2011, 41:529-542.
-
(2011)
Mol. Cell
, vol.41
, pp. 529-542
-
-
Moyal, L.1
Lerenthal, Y.2
Gana-Weisz, M.3
Mass, G.4
So, S.5
Wang, S.Y.6
Eppink, B.7
Chung, Y.M.8
Shalev, G.9
Shema, E.10
Shkedy, D.11
Smorodinsky, N.I.12
van Vliet, N.13
Kuster, B.14
Mann, M.15
Ciechanover, A.16
Dahm-Daphi, J.17
Kanaar, R.18
Hu, M.C.19
Chen, D.J.20
Oren, M.21
Shiloh, Y.22
more..
-
40
-
-
79951971464
-
Regulation of homologous recombination by RNF20-dependent H2B ubiquitination
-
Nakamura K., Kato A., Kobayashi J., Yanagihara H., Sakamoto S., Oliveira D.V., Shimada M., Tauchi H., Suzuki H., Tashiro S., Zou L., Komatsu K. Regulation of homologous recombination by RNF20-dependent H2B ubiquitination. Mol. Cell 2011, 41:515-528.
-
(2011)
Mol. Cell
, vol.41
, pp. 515-528
-
-
Nakamura, K.1
Kato, A.2
Kobayashi, J.3
Yanagihara, H.4
Sakamoto, S.5
Oliveira, D.V.6
Shimada, M.7
Tauchi, H.8
Suzuki, H.9
Tashiro, S.10
Zou, L.11
Komatsu, K.12
-
41
-
-
77953720192
-
ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks
-
Shanbhag N.M., Rafalska-Metcalf I.U., Balane-Bolivar C., Janicki S.M., Greenberg R.A. ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks. Cell 2010, 141:970-981.
-
(2010)
Cell
, vol.141
, pp. 970-981
-
-
Shanbhag, N.M.1
Rafalska-Metcalf, I.U.2
Balane-Bolivar, C.3
Janicki, S.M.4
Greenberg, R.A.5
-
42
-
-
7244234099
-
Role of histone H2A ubiquitination in Polycomb silencing
-
Wang H., Wang L., Erdjument-Bromage H., Vidal M., Tempst P., Jones R.S., Zhang Y. Role of histone H2A ubiquitination in Polycomb silencing. Nature 2004, 431:873-878.
-
(2004)
Nature
, vol.431
, pp. 873-878
-
-
Wang, H.1
Wang, L.2
Erdjument-Bromage, H.3
Vidal, M.4
Tempst, P.5
Jones, R.S.6
Zhang, Y.7
-
43
-
-
33646691283
-
Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II
-
Pavri R., Zhu B., Li G., Trojer P., Mandal S., Shilatifard A., Reinberg D. Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II. Cell 2006, 19:703-717.
-
(2006)
Cell
, vol.19
, pp. 703-717
-
-
Pavri, R.1
Zhu, B.2
Li, G.3
Trojer, P.4
Mandal, S.5
Shilatifard, A.6
Reinberg, D.7
-
44
-
-
79956086415
-
BMI1 is recruited to DNA breaks and contributes to DNA damage-induced H2A ubiquitination and repair
-
Ginjala V., Nacerddine K., Kulkarni A., Oza J., Hill S.J., Yao M., Citterio E., van Lohuizen M., Ganesan S. BMI1 is recruited to DNA breaks and contributes to DNA damage-induced H2A ubiquitination and repair. Mol. Cell. Biol. 2011, 31:1972-1982.
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 1972-1982
-
-
Ginjala, V.1
Nacerddine, K.2
Kulkarni, A.3
Oza, J.4
Hill, S.J.5
Yao, M.6
Citterio, E.7
van Lohuizen, M.8
Ganesan, S.9
-
45
-
-
72449175818
-
Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks
-
Galanty Y., Belotserkovskaya R., Coates J., Polo S., Miller K.M., Jackson S.P. Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks. Nature 2009, 462:935-939.
-
(2009)
Nature
, vol.462
, pp. 935-939
-
-
Galanty, Y.1
Belotserkovskaya, R.2
Coates, J.3
Polo, S.4
Miller, K.M.5
Jackson, S.P.6
-
46
-
-
80052697814
-
The ubiquitin- and SUMO-dependent signaling response to DNA double-strand breaks
-
Bekker-Jensen S., Mailand N. The ubiquitin- and SUMO-dependent signaling response to DNA double-strand breaks. FEBS Lett. 2011, 585:2914-2919.
-
(2011)
FEBS Lett.
, vol.585
, pp. 2914-2919
-
-
Bekker-Jensen, S.1
Mailand, N.2
-
47
-
-
59649124496
-
Chromosome-wide Rad51 spreading and SUMO-H2A.Z-dependent chromosome fixation in response to a persistent DNA double-strand break
-
Kalocsay M., Hiller N.J., Jentsch S. Chromosome-wide Rad51 spreading and SUMO-H2A.Z-dependent chromosome fixation in response to a persistent DNA double-strand break. Mol. Cell 2009, 33:335-343.
-
(2009)
Mol. Cell
, vol.33
, pp. 335-343
-
-
Kalocsay, M.1
Hiller, N.J.2
Jentsch, S.3
-
48
-
-
33845666681
-
Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair
-
Botuyan M.V., Lee J., Ward I.M., Kim J.E., Thompson J.R., Chen J., Mer G. Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair. Cell 2006, 127:1361-1373.
-
(2006)
Cell
, vol.127
, pp. 1361-1373
-
-
Botuyan, M.V.1
Lee, J.2
Ward, I.M.3
Kim, J.E.4
Thompson, J.R.5
Chen, J.6
Mer, G.7
-
50
-
-
79551665780
-
MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites
-
Pei H., Zhang L., Luo K., Qin Y., Chesi M., Fei F., Bergsagel P.L., Wang L., You Z., Lou Z. MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites. Nature 2011, 470:124-128.
-
(2011)
Nature
, vol.470
, pp. 124-128
-
-
Pei, H.1
Zhang, L.2
Luo, K.3
Qin, Y.4
Chesi, M.5
Fei, F.6
Bergsagel, P.L.7
Wang, L.8
You, Z.9
Lou, Z.10
-
51
-
-
9244252580
-
Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks
-
Huyen Y., Zgheib O., Ditullio R.A., Gorgoulis V.G., Zacharatos P., Petty T.J., Sheston E.A., Mellert H.S., Stavridi E.S., Halazonetis T.D. Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks. Nature 2004, 432:406-411.
-
(2004)
Nature
, vol.432
, pp. 406-411
-
-
Huyen, Y.1
Zgheib, O.2
Ditullio, R.A.3
Gorgoulis, V.G.4
Zacharatos, P.5
Petty, T.J.6
Sheston, E.A.7
Mellert, H.S.8
Stavridi, E.S.9
Halazonetis, T.D.10
-
52
-
-
77950958141
-
53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks
-
Bunting S.F., Callen E., Wong N., Chen H.T., Polato F., Gunn A., Bothmer A., Feldhahn N., Fernandez-Capetillo O., Cao L., Xu X., Deng C.X., Finkel T., Nussenzweig M., Stark J.M., Nussenzweig A. 53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks. Cell 2010, 141:243-254.
-
(2010)
Cell
, vol.141
, pp. 243-254
-
-
Bunting, S.F.1
Callen, E.2
Wong, N.3
Chen, H.T.4
Polato, F.5
Gunn, A.6
Bothmer, A.7
Feldhahn, N.8
Fernandez-Capetillo, O.9
Cao, L.10
Xu, X.11
Deng, C.X.12
Finkel, T.13
Nussenzweig, M.14
Stark, J.M.15
Nussenzweig, A.16
-
53
-
-
77953291328
-
53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers
-
Bouwman P., Aly A., Escandell J.M., Pieterse M., Bartkova J., van der Gulden H., Hiddingh S., Thanasoula M., Kulkarni A., Yang Q., Haffty B.G., Tommiska J., Blomqvist C., Drapkin R., Adams D.J., Nevanlinna H., Bartek J., Tarsounas M., Ganesan S., Jonkers J. 53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers. Nat. Struct. Mol. Biol. 2010, 17:688-695.
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 688-695
-
-
Bouwman, P.1
Aly, A.2
Escandell, J.M.3
Pieterse, M.4
Bartkova, J.5
van der Gulden, H.6
Hiddingh, S.7
Thanasoula, M.8
Kulkarni, A.9
Yang, Q.10
Haffty, B.G.11
Tommiska, J.12
Blomqvist, C.13
Drapkin, R.14
Adams, D.J.15
Nevanlinna, H.16
Bartek, J.17
Tarsounas, M.18
Ganesan, S.19
Jonkers, J.20
more..
-
54
-
-
33748272677
-
Interplay between Ino80 and Swr1 chromatin remodeling enzymes regulates cell cycle checkpoint adaptation in response to DNA damage
-
Papamichos-Chronakis M., Krebs J.E., Peterson C.L. Interplay between Ino80 and Swr1 chromatin remodeling enzymes regulates cell cycle checkpoint adaptation in response to DNA damage. Genes Dev. 2006, 20:2437-2449.
-
(2006)
Genes Dev.
, vol.20
, pp. 2437-2449
-
-
Papamichos-Chronakis, M.1
Krebs, J.E.2
Peterson, C.L.3
-
55
-
-
10844233155
-
Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions
-
Kusch T., Florens L., Macdonald W.H., Swanson S.K., Glaser R.L., Yates J.R., Abmayr S.M., Washburn M.P., Workman J.L. Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions. Science 2004, 306:2084-2087.
-
(2004)
Science
, vol.306
, pp. 2084-2087
-
-
Kusch, T.1
Florens, L.2
Macdonald, W.H.3
Swanson, S.K.4
Glaser, R.L.5
Yates, J.R.6
Abmayr, S.M.7
Washburn, M.P.8
Workman, J.L.9
-
56
-
-
69949133036
-
A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation
-
Timinszky G., Till S., Hassa P.O., Hothorn M., Kustatscher G., Nijmeijer B., Colombelli J., Altmeyer M., Stelzer E.H., Scheffzek K., Hottiger M.O., Ladurner A.G. A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation. Nat. Struct. Mol. Biol. 2009, 16:923-929.
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 923-929
-
-
Timinszky, G.1
Till, S.2
Hassa, P.O.3
Hothorn, M.4
Kustatscher, G.5
Nijmeijer, B.6
Colombelli, J.7
Altmeyer, M.8
Stelzer, E.H.9
Scheffzek, K.10
Hottiger, M.O.11
Ladurner, A.G.12
-
57
-
-
79957575681
-
PARP-1 and PARP-2: new players in tumour development
-
Yelamos J., Farres J., Llacuna L., Ampurdanes C., Martin-Caballero J. PARP-1 and PARP-2: new players in tumour development. Am. J. Cancer Res. 2011, 1:328-346.
-
(2011)
Am. J. Cancer Res.
, vol.1
, pp. 328-346
-
-
Yelamos, J.1
Farres, J.2
Llacuna, L.3
Ampurdanes, C.4
Martin-Caballero, J.5
-
58
-
-
31344480648
-
Mechanism of polymerase II transcription repression by the histone variant macroH2A
-
Doyen C.M., An W., Angelov D., Bondarenko V., Mietton F., Studitsky V.M., Hamiche A., Roeder R.G., Bouvet P., Dimitrov S. Mechanism of polymerase II transcription repression by the histone variant macroH2A. Mol. Cell. Biol. 2006, 26:1156-1164.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 1156-1164
-
-
Doyen, C.M.1
An, W.2
Angelov, D.3
Bondarenko, V.4
Mietton, F.5
Studitsky, V.M.6
Hamiche, A.7
Roeder, R.G.8
Bouvet, P.9
Dimitrov, S.10
-
59
-
-
10944227347
-
NAD+-dependent modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1
-
Kim M.Y., Mauro S., Gevry N., Lis J.T., Kraus W.L. NAD+-dependent modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1. Cell 2004, 119:803-814.
-
(2004)
Cell
, vol.119
, pp. 803-814
-
-
Kim, M.Y.1
Mauro, S.2
Gevry, N.3
Lis, J.T.4
Kraus, W.L.5
-
60
-
-
77956526559
-
PARP-1 regulates chromatin structure and transcription through a KDM5B-dependent pathway
-
Krishnakumar R., Kraus W.L. PARP-1 regulates chromatin structure and transcription through a KDM5B-dependent pathway. Mol. Cell 2010, 39:736-749.
-
(2010)
Mol. Cell
, vol.39
, pp. 736-749
-
-
Krishnakumar, R.1
Kraus, W.L.2
-
61
-
-
34250022502
-
The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks
-
Kruhlak M., Crouch E.E., Orlov M., Montano C., Gorski S.A., Nussenzweig A., Misteli T., Phair R.D., Casellas R. The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks. Nature 2007, 447:730-734.
-
(2007)
Nature
, vol.447
, pp. 730-734
-
-
Kruhlak, M.1
Crouch, E.E.2
Orlov, M.3
Montano, C.4
Gorski, S.A.5
Nussenzweig, A.6
Misteli, T.7
Phair, R.D.8
Casellas, R.9
-
62
-
-
66149094160
-
Heterochromatin protein 1 is recruited to various types of DNA damage
-
Luijsterburg M.S., Dinant C., Lans H., Stap J., Wiernasz E., Lagerwerf S., Warmerdam D.O., Lindh M., Brink M.C., Dobrucki J.W., Aten J.A., Fousteri M.I., Jansen G., Dantuma N.P., Vermeulen W., Mullenders L.H., Houtsmuller A.B., Verschure P.J., van Driel R. Heterochromatin protein 1 is recruited to various types of DNA damage. J. Cell Biol. 2009, 185:577-586.
-
(2009)
J. Cell Biol.
, vol.185
, pp. 577-586
-
-
Luijsterburg, M.S.1
Dinant, C.2
Lans, H.3
Stap, J.4
Wiernasz, E.5
Lagerwerf, S.6
Warmerdam, D.O.7
Lindh, M.8
Brink, M.C.9
Dobrucki, J.W.10
Aten, J.A.11
Fousteri, M.I.12
Jansen, G.13
Dantuma, N.P.14
Vermeulen, W.15
Mullenders, L.H.16
Houtsmuller, A.B.17
Verschure, P.J.18
van Driel, R.19
-
63
-
-
79955507697
-
HP1alpha recruitment to DNA damage by p150CAF-1 promotes homologous recombination repair
-
Baldeyron C., Soria G., Roche D., Cook A.J., Almouzni G. HP1alpha recruitment to DNA damage by p150CAF-1 promotes homologous recombination repair. J. Cell Biol. 2011, 193:81-95.
-
(2011)
J. Cell Biol.
, vol.193
, pp. 81-95
-
-
Baldeyron, C.1
Soria, G.2
Roche, D.3
Cook, A.J.4
Almouzni, G.5
-
64
-
-
44449136965
-
HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response
-
Ayoub N., Jeyasekharan A.D., Bernal J.A., Venkitaraman A.R. HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response. Nature 2008, 453:682-686.
-
(2008)
Nature
, vol.453
, pp. 682-686
-
-
Ayoub, N.1
Jeyasekharan, A.D.2
Bernal, J.A.3
Venkitaraman, A.R.4
-
65
-
-
73449088051
-
Mobilization and recruitment of HP1: a bimodal response to DNA breakage
-
Ayoub N., Jeyasekharan A.D., Venkitaraman A.R. Mobilization and recruitment of HP1: a bimodal response to DNA breakage. Cell Cycle 2009, 8:2945-2950.
-
(2009)
Cell Cycle
, vol.8
, pp. 2945-2950
-
-
Ayoub, N.1
Jeyasekharan, A.D.2
Venkitaraman, A.R.3
-
66
-
-
44449154833
-
DNA damage, homology-directed repair, and DNA methylation
-
Cuozzo C., Porcellini A., Angrisano T., Morano A., Lee B., Di Pardo A., Messina S., Iuliano R., Fusco A., Santillo M.R., Muller M.T., Chiariotti L., Gottesman M.E., Avvedimento E.V. DNA damage, homology-directed repair, and DNA methylation. PLoS Genet. 2007, 3:e110.
-
(2007)
PLoS Genet.
, vol.3
-
-
Cuozzo, C.1
Porcellini, A.2
Angrisano, T.3
Morano, A.4
Lee, B.5
Di Pardo, A.6
Messina, S.7
Iuliano, R.8
Fusco, A.9
Santillo, M.R.10
Muller, M.T.11
Chiariotti, L.12
Gottesman, M.E.13
Avvedimento, E.V.14
-
67
-
-
78549288551
-
DNA methyltransferase 1-associated protein (DMAP1) is a co-repressor that stimulates DNA methylation globally and locally at sites of double strand break repair
-
Lee G.E., Kim J.H., Taylor M., Muller M.T. DNA methyltransferase 1-associated protein (DMAP1) is a co-repressor that stimulates DNA methylation globally and locally at sites of double strand break repair. J. Biol. Chem. 2010, 285:37630-37640.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 37630-37640
-
-
Lee, G.E.1
Kim, J.H.2
Taylor, M.3
Muller, M.T.4
-
68
-
-
50849104569
-
Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island
-
O'Hagan H.M., Mohammad H.P., Baylin S.B. Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island. PLoS Genet. 2008, 4:e1000155.
-
(2008)
PLoS Genet.
, vol.4
-
-
O'Hagan, H.M.1
Mohammad, H.P.2
Baylin, S.B.3
-
69
-
-
81255162523
-
Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG islands
-
O'Hagan H.M., Wang W., Sen S., Shields C.D., Lee S.S., Zhang Y.W., Clements E.G., Cai Y., Van Neste L., Easwaran H., Casero R.A., Sears C.L., Baylin S.B. Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG islands. Cancer Cell 2011, 20:606-619.
-
(2011)
Cancer Cell
, vol.20
, pp. 606-619
-
-
O'Hagan, H.M.1
Wang, W.2
Sen, S.3
Shields, C.D.4
Lee, S.S.5
Zhang, Y.W.6
Clements, E.G.7
Cai, Y.8
Van Neste, L.9
Easwaran, H.10
Casero, R.A.11
Sears, C.L.12
Baylin, S.B.13
-
70
-
-
34447574977
-
Positional stability of single double-strand breaks in mammalian cells
-
Soutoglou E., Dorn J.F., Sengupta K., Jasin M., Nussenzweig A., Ried T., Danuser G., Misteli T. Positional stability of single double-strand breaks in mammalian cells. Nat. Cell Biol. 2007, 9:675-682.
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 675-682
-
-
Soutoglou, E.1
Dorn, J.F.2
Sengupta, K.3
Jasin, M.4
Nussenzweig, A.5
Ried, T.6
Danuser, G.7
Misteli, T.8
-
71
-
-
79955490586
-
Replication stress induces 53BP1-containing OPT domains in G1 cells
-
Harrigan J.A., Belotserkovskaya R., Coates J., Dimitrova D.S., Polo S.E., Bradshaw C.R., Fraser P., Jackson S.P. Replication stress induces 53BP1-containing OPT domains in G1 cells. J. Cell Biol. 2011, 193:97-108.
-
(2011)
J. Cell Biol.
, vol.193
, pp. 97-108
-
-
Harrigan, J.A.1
Belotserkovskaya, R.2
Coates, J.3
Dimitrova, D.S.4
Polo, S.E.5
Bradshaw, C.R.6
Fraser, P.7
Jackson, S.P.8
-
72
-
-
79952281751
-
53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress
-
Lukas C., Savic V., Bekker-Jensen S., Doil C., Neumann B., Pedersen R.S., Grofte M., Chan K.L., Hickson I.D., Bartek J., Lukas J. 53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress. Nat. Cell Biol. 2011, 13:243-253.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 243-253
-
-
Lukas, C.1
Savic, V.2
Bekker-Jensen, S.3
Doil, C.4
Neumann, B.5
Pedersen, R.S.6
Grofte, M.7
Chan, K.L.8
Hickson, I.D.9
Bartek, J.10
Lukas, J.11
-
75
-
-
0035815360
-
Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly
-
Nakayama J., Rice J.C., Strahl B.D., Allis C.D., Grewal S.I. Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly. Science 2001, 292:110-113.
-
(2001)
Science
, vol.292
, pp. 110-113
-
-
Nakayama, J.1
Rice, J.C.2
Strahl, B.D.3
Allis, C.D.4
Grewal, S.I.5
-
76
-
-
63449109369
-
Heterochromatic genome stability requires regulators of histone H3 K9 methylation
-
Peng J.C., Karpen G.H. Heterochromatic genome stability requires regulators of histone H3 K9 methylation. PLoS Genet. 2009, 5:e1000435.
-
(2009)
PLoS Genet.
, vol.5
-
-
Peng, J.C.1
Karpen, G.H.2
-
77
-
-
0036185952
-
Recombinogenic effects of suppressors of position-effect variegation in Drosophila
-
Westphal T., Reuter G. Recombinogenic effects of suppressors of position-effect variegation in Drosophila. Genetics 2002, 160:609-621.
-
(2002)
Genetics
, vol.160
, pp. 609-621
-
-
Westphal, T.1
Reuter, G.2
-
78
-
-
34447532525
-
Heterochromatin is refractory to gamma-H2AX modification in yeast and mammals
-
Kim J.A., Kruhlak M., Dotiwala F., Nussenzweig A., Haber J.E. Heterochromatin is refractory to gamma-H2AX modification in yeast and mammals. J. Cell Biol. 2007, 178:209-218.
-
(2007)
J. Cell Biol.
, vol.178
, pp. 209-218
-
-
Kim, J.A.1
Kruhlak, M.2
Dotiwala, F.3
Nussenzweig, A.4
Haber, J.E.5
-
79
-
-
42249102663
-
GammaH2AX foci form preferentially in euchromatin after ionising-radiation
-
Cowell I.G., Sunter N.J., Singh P.B., Austin C.A., Durkacz B.W., Tilby M.J. GammaH2AX foci form preferentially in euchromatin after ionising-radiation. PLoS One 2007, 2:e1057.
-
(2007)
PLoS One
, vol.2
-
-
Cowell, I.G.1
Sunter, N.J.2
Singh, P.B.3
Austin, C.A.4
Durkacz, B.W.5
Tilby, M.J.6
-
80
-
-
47349107760
-
ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin
-
Goodarzi A.A., Noon A.T., Deckbar D., Ziv Y., Shiloh Y., Lobrich M., Jeggo P.A. ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin. Mol. Cell 2008, 31:167-177.
-
(2008)
Mol. Cell
, vol.31
, pp. 167-177
-
-
Goodarzi, A.A.1
Noon, A.T.2
Deckbar, D.3
Ziv, Y.4
Shiloh, Y.5
Lobrich, M.6
Jeggo, P.A.7
-
81
-
-
34547591933
-
The Smc5-Smc6 complex and SUMO modification of Rad52 regulates recombinational repair at the ribosomal gene locus
-
Torres-Rosell J., Sunjevaric I., De Piccoli G., Sacher M., Eckert-Boulet N., Reid R., Jentsch S., Rothstein R., Aragon L., Lisby M. The Smc5-Smc6 complex and SUMO modification of Rad52 regulates recombinational repair at the ribosomal gene locus. Nat. Cell Biol. 2007, 9:923-931.
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 923-931
-
-
Torres-Rosell, J.1
Sunjevaric, I.2
De Piccoli, G.3
Sacher, M.4
Eckert-Boulet, N.5
Reid, R.6
Jentsch, S.7
Rothstein, R.8
Aragon, L.9
Lisby, M.10
-
82
-
-
34548731510
-
Can eukaryotic cells monitor the presence of unreplicated DNA?
-
Torres-Rosell J., De Piccoli G., Aragon L. Can eukaryotic cells monitor the presence of unreplicated DNA?. Cell Div. 2007, 2:19.
-
(2007)
Cell Div.
, vol.2
, pp. 19
-
-
Torres-Rosell, J.1
De Piccoli, G.2
Aragon, L.3
-
83
-
-
79952314830
-
Double-strand breaks in heterochromatin move outside of a dynamic HP1a domain to complete recombinational repair
-
Chiolo I., Minoda A., Colmenares S.U., Polyzos A., Costes S.V., Karpen G.H. Double-strand breaks in heterochromatin move outside of a dynamic HP1a domain to complete recombinational repair. Cell 2011, 144:732-744.
-
(2011)
Cell
, vol.144
, pp. 732-744
-
-
Chiolo, I.1
Minoda, A.2
Colmenares, S.U.3
Polyzos, A.4
Costes, S.V.5
Karpen, G.H.6
-
84
-
-
19944427674
-
Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA
-
Zhang R., Poustovoitov M.V., Ye X., Santos H.A., Chen W., Daganzo S.M., Erzberger J.P., Serebriiskii I.G., Canutescu A.A., Dunbrack R.L., Pehrson J.R., Berger J.M., Kaufman P.D., Adams P.D. Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA. Dev. Cell 2005, 8:19-30.
-
(2005)
Dev. Cell
, vol.8
, pp. 19-30
-
-
Zhang, R.1
Poustovoitov, M.V.2
Ye, X.3
Santos, H.A.4
Chen, W.5
Daganzo, S.M.6
Erzberger, J.P.7
Serebriiskii, I.G.8
Canutescu, A.A.9
Dunbrack, R.L.10
Pehrson, J.R.11
Berger, J.M.12
Kaufman, P.D.13
Adams, P.D.14
-
85
-
-
0037667702
-
Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence
-
Narita M., Nunez S., Heard E., Lin A.W., Hearn S.A., Spector D.L., Hannon G.J., Lowe S.W. Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence. Cell 2003, 113:703-716.
-
(2003)
Cell
, vol.113
, pp. 703-716
-
-
Narita, M.1
Nunez, S.2
Heard, E.3
Lin, A.W.4
Hearn, S.A.5
Spector, D.L.6
Hannon, G.J.7
Lowe, S.W.8
-
86
-
-
79952268809
-
Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer
-
Di Micco R., Sulli G., Dobreva M., Liontos M., Botrugno O.A., Gargiulo G., dal Zuffo R., Matti V., d'Ario G., Montani E., Mercurio C., Hahn W.C., Gorgoulis V., Minucci S., d'Adda di Fagagna F. Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer. Nat. Cell Biol. 2011, 13:292-302.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 292-302
-
-
Di Micco, R.1
Sulli, G.2
Dobreva, M.3
Liontos, M.4
Botrugno, O.A.5
Gargiulo, G.6
dal Zuffo, R.7
Matti, V.8
d'Ario, G.9
Montani, E.10
Mercurio, C.11
Hahn, W.C.12
Gorgoulis, V.13
Minucci, S.14
d'Adda di Fagagna, F.15
-
87
-
-
0033612189
-
MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks
-
Mills K.D., Sinclair D.A., Guarente L. MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks. Cell 1999, 97:609-620.
-
(1999)
Cell
, vol.97
, pp. 609-620
-
-
Mills, K.D.1
Sinclair, D.A.2
Guarente, L.3
-
88
-
-
0030053650
-
Loss of transcriptional silencing causes sterility in old mother cells of S. cerevisiae
-
Smeal T., Claus J., Kennedy B., Cole F., Guarente L. Loss of transcriptional silencing causes sterility in old mother cells of S. cerevisiae. Cell 1996, 84:633-642.
-
(1996)
Cell
, vol.84
, pp. 633-642
-
-
Smeal, T.1
Claus, J.2
Kennedy, B.3
Cole, F.4
Guarente, L.5
-
89
-
-
0033612287
-
Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast
-
Martin S.G., Laroche T., Suka N., Grunstein M., Gasser S.M. Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast. Cell 1999, 97:621-633.
-
(1999)
Cell
, vol.97
, pp. 621-633
-
-
Martin, S.G.1
Laroche, T.2
Suka, N.3
Grunstein, M.4
Gasser, S.M.5
-
90
-
-
0033539095
-
DNA damage triggers disruption of telomeric silencing and Mec1p-dependent relocation of Sir3p
-
McAinsh A.D., Scott-Drew S., Murray J.A., Jackson S.P. DNA damage triggers disruption of telomeric silencing and Mec1p-dependent relocation of Sir3p. Curr. Biol. 1999, 9:963-966.
-
(1999)
Curr. Biol.
, vol.9
, pp. 963-966
-
-
McAinsh, A.D.1
Scott-Drew, S.2
Murray, J.A.3
Jackson, S.P.4
-
91
-
-
56749156405
-
SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging
-
Oberdoerffer P., Michan S., McVay M., Mostoslavsky R., Vann J., Park S.K., Hartlerode A., Stegmuller J., Hafner A., Loerch P., Wright S.M., Mills K.D., Bonni A., Yankner B.A., Scully R., Prolla T.A., Alt F.W., Sinclair D.A. SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging. Cell 2008, 135:907-918.
-
(2008)
Cell
, vol.135
, pp. 907-918
-
-
Oberdoerffer, P.1
Michan, S.2
McVay, M.3
Mostoslavsky, R.4
Vann, J.5
Park, S.K.6
Hartlerode, A.7
Stegmuller, J.8
Hafner, A.9
Loerch, P.10
Wright, S.M.11
Mills, K.D.12
Bonni, A.13
Yankner, B.A.14
Scully, R.15
Prolla, T.A.16
Alt, F.W.17
Sinclair, D.A.18
-
92
-
-
34548150187
-
The role of nuclear architecture in genomic instability and ageing
-
Oberdoerffer P., Sinclair D.A. The role of nuclear architecture in genomic instability and ageing. Nat. Rev. Mol. Cell Biol. 2007, 8:692-702.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 692-702
-
-
Oberdoerffer, P.1
Sinclair, D.A.2
-
93
-
-
0022476994
-
Induction of chromosome shattering by ultraviolet light and caffeine: the influence of different distributions of photolesions
-
Cremer C., Cremer T. Induction of chromosome shattering by ultraviolet light and caffeine: the influence of different distributions of photolesions. Mutat. Res. 1986, 163:33-40.
-
(1986)
Mutat. Res.
, vol.163
, pp. 33-40
-
-
Cremer, C.1
Cremer, T.2
-
94
-
-
80052567822
-
BRCA1 tumour suppression occurs via heterochromatin-mediated silencing
-
Zhu Q., Pao G.M., Huynh A.M., Suh H., Tonnu N., Nederlof P.M., Gage F.H., Verma I.M. BRCA1 tumour suppression occurs via heterochromatin-mediated silencing. Nature 2011, 477:179-184.
-
(2011)
Nature
, vol.477
, pp. 179-184
-
-
Zhu, Q.1
Pao, G.M.2
Huynh, A.M.3
Suh, H.4
Tonnu, N.5
Nederlof, P.M.6
Gage, F.H.7
Verma, I.M.8
-
95
-
-
34447549077
-
Postreplicative formation of cohesion is required for repair and induced by a single DNA break
-
Strom L., Karlsson C., Lindroos H.B., Wedahl S., Katou Y., Shirahige K., Sjogren C. Postreplicative formation of cohesion is required for repair and induced by a single DNA break. Science 2007, 317:242-245.
-
(2007)
Science
, vol.317
, pp. 242-245
-
-
Strom, L.1
Karlsson, C.2
Lindroos, H.B.3
Wedahl, S.4
Katou, Y.5
Shirahige, K.6
Sjogren, C.7
-
96
-
-
34447536708
-
DNA double-strand breaks trigger genome-wide sister-chromatid cohesion through Eco1 (Ctf7)
-
Unal E., Heidinger-Pauli J.M., Koshland D. DNA double-strand breaks trigger genome-wide sister-chromatid cohesion through Eco1 (Ctf7). Science 2007, 317:245-248.
-
(2007)
Science
, vol.317
, pp. 245-248
-
-
Unal, E.1
Heidinger-Pauli, J.M.2
Koshland, D.3
-
97
-
-
77954901707
-
Genome-wide reinforcement of cohesin binding at pre-existing cohesin sites in response to ionizing radiation in human cells
-
Kim B.J., Li Y., Zhang J., Xi Y., Yang T., Jung S.Y., Pan X., Chen R., Li W., Wang Y., Qin J. Genome-wide reinforcement of cohesin binding at pre-existing cohesin sites in response to ionizing radiation in human cells. J. Biol. Chem. 2010, 285:22784-22792.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 22784-22792
-
-
Kim, B.J.1
Li, Y.2
Zhang, J.3
Xi, Y.4
Yang, T.5
Jung, S.Y.6
Pan, X.7
Chen, R.8
Li, W.9
Wang, Y.10
Qin, J.11
-
98
-
-
77957814604
-
Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres
-
O'Sullivan R.J., Kubicek S., Schreiber S.L., Karlseder J. Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres. Nat. Struct. Mol. Biol. 2010, 17:1218-1225.
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 1218-1225
-
-
O'Sullivan, R.J.1
Kubicek, S.2
Schreiber, S.L.3
Karlseder, J.4
-
99
-
-
78149235231
-
An age of fewer histones
-
Oberdoerffer P. An age of fewer histones. Nat. Cell Biol. 2010, 12:1029-1031.
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 1029-1031
-
-
Oberdoerffer, P.1
-
100
-
-
77956520661
-
Elevated histone expression promotes life span extension
-
Feser J., Truong D., Das C., Carson J.J., Kieft J., Harkness T., Tyler J.K. Elevated histone expression promotes life span extension. Mol. Cell 2010, 39:724-735.
-
(2010)
Mol. Cell
, vol.39
, pp. 724-735
-
-
Feser, J.1
Truong, D.2
Das, C.3
Carson, J.J.4
Kieft, J.5
Harkness, T.6
Tyler, J.K.7
-
102
-
-
63849135037
-
PML nuclear bodies as sites of epigenetic regulation
-
Torok D., Ching R.W., Bazett-Jones D.P. PML nuclear bodies as sites of epigenetic regulation. Front. Biosci. 2009, 14:1325-1336.
-
(2009)
Front. Biosci.
, vol.14
, pp. 1325-1336
-
-
Torok, D.1
Ching, R.W.2
Bazett-Jones, D.P.3
-
103
-
-
33749547681
-
Promyelocytic leukemia nuclear bodies behave as DNA damage sensors whose response to DNA double-strand breaks is regulated by NBS1 and the kinases ATM, Chk2, and ATR
-
Dellaire G., Ching R.W., Ahmed K., Jalali F., Tse K.C., Bristow R.G., Bazett-Jones D.P. Promyelocytic leukemia nuclear bodies behave as DNA damage sensors whose response to DNA double-strand breaks is regulated by NBS1 and the kinases ATM, Chk2, and ATR. J. Cell Biol. 2006, 175:55-66.
-
(2006)
J. Cell Biol.
, vol.175
, pp. 55-66
-
-
Dellaire, G.1
Ching, R.W.2
Ahmed, K.3
Jalali, F.4
Tse, K.C.5
Bristow, R.G.6
Bazett-Jones, D.P.7
-
104
-
-
0037034829
-
PML NBs associate with the hMre11 complex and p53 at sites of irradiation induced DNA damage
-
Carbone R., Pearson M., Minucci S., Pelicci P.G. PML NBs associate with the hMre11 complex and p53 at sites of irradiation induced DNA damage. Oncogene 2002, 21:1633-1640.
-
(2002)
Oncogene
, vol.21
, pp. 1633-1640
-
-
Carbone, R.1
Pearson, M.2
Minucci, S.3
Pelicci, P.G.4
-
105
-
-
0031791875
-
PML is essential for multiple apoptotic pathways
-
Wang Z.G., Ruggero D., Ronchetti S., Zhong S., Gaboli M., Rivi R., Pandolfi P.P. PML is essential for multiple apoptotic pathways. Nat. Genet. 1998, 20:266-272.
-
(1998)
Nat. Genet.
, vol.20
, pp. 266-272
-
-
Wang, Z.G.1
Ruggero, D.2
Ronchetti, S.3
Zhong, S.4
Gaboli, M.5
Rivi, R.6
Pandolfi, P.P.7
-
106
-
-
0035910747
-
Role of promyelocytic leukemia (PML) protein in tumor suppression
-
Rego E.M., Wang Z.G., Peruzzi D., He L.Z., Cordon-Cardo C., Pandolfi P.P. Role of promyelocytic leukemia (PML) protein in tumor suppression. J. Exp. Med. 2001, 193:521-529.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 521-529
-
-
Rego, E.M.1
Wang, Z.G.2
Peruzzi, D.3
He, L.Z.4
Cordon-Cardo, C.5
Pandolfi, P.P.6
-
107
-
-
0033598931
-
A role for PML and the nuclear body in genomic stability
-
Zhong S., Hu P., Ye T.Z., Stan R., Ellis N.A., Pandolfi P.P. A role for PML and the nuclear body in genomic stability. Oncogene 1999, 18:7941-7947.
-
(1999)
Oncogene
, vol.18
, pp. 7941-7947
-
-
Zhong, S.1
Hu, P.2
Ye, T.Z.3
Stan, R.4
Ellis, N.A.5
Pandolfi, P.P.6
-
108
-
-
78649336111
-
The nucleolus under stress
-
Boulon S., Westman B.J., Hutten S., Boisvert F.M., Lamond A.I. The nucleolus under stress. Mol. Cell 2010, 40:216-227.
-
(2010)
Mol. Cell
, vol.40
, pp. 216-227
-
-
Boulon, S.1
Westman, B.J.2
Hutten, S.3
Boisvert, F.M.4
Lamond, A.I.5
-
109
-
-
77956274850
-
Recruitment of phosphorylated NPM1 to sites of DNA damage through RNF8-dependent ubiquitin conjugates
-
Koike A., Nishikawa H., Wu W., Okada Y., Venkitaraman A.R., Ohta T. Recruitment of phosphorylated NPM1 to sites of DNA damage through RNF8-dependent ubiquitin conjugates. Cancer Res. 2010, 70:6746-6756.
-
(2010)
Cancer Res.
, vol.70
, pp. 6746-6756
-
-
Koike, A.1
Nishikawa, H.2
Wu, W.3
Okada, Y.4
Venkitaraman, A.R.5
Ohta, T.6
-
110
-
-
66049160126
-
The ageing epigenome: damaged beyond repair?
-
Sinclair D.A., Oberdoerffer P. The ageing epigenome: damaged beyond repair?. Ageing Res. Rev. 2009, 8:189-198.
-
(2009)
Ageing Res. Rev.
, vol.8
, pp. 189-198
-
-
Sinclair, D.A.1
Oberdoerffer, P.2
|