Sirt2 deacetylase is a novel AKT Binding partner critical for AKT activation by insulin

Journal of Biological Chemistry

Volumn 289, Issue 9, 2014, Pages 6054-6066

  Ramakrishnan, Gopalakrishnan ^a   Davaakhuu, Gantulga ^a   Kaplun, Ludmila ^b   Chung, Wen Cheng ^a   Rana, Ajay ^c   Atfi, Azeddine ^a   Miele, Lucio ^a   Tzivion, Guri ^a,b  

^a UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

^b WAYNE STATE UNIVERSITY   (United States)

^c LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMP-ACTIVATED KINASE; CANCER PATHOGENESIS; DOWNSTREAM TARGET; INSULIN RESISTANCE; METABOLIC DISORDERS; PHARMACOLOGICAL INHIBITION; PHOSPHATIDYLINOSITOL 3-KINASE; PLECKSTRIN HOMOLOGY;

ACTIVATION ANALYSIS; CELLS; CYTOLOGY; ENZYMES; METABOLISM; PHOSPHORYLATION;

INSULIN;

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PHOSPHATIDYLINOSITOL 3 KINASE; PLECKSTRIN; PROTEIN KINASE B; SIRTUIN 2;

ANIMAL CELL; ARTICLE; CELL SUBPOPULATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

AKT; AMP-ACTIVATED KINASE (AMPK); INSULIN; PHOSPHORYLATION; SIRTUINS;

3T3-L1 CELLS; ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; ENZYME ACTIVATION; HELA CELLS; HUMANS; INSULIN; MICE; NIH 3T3 CELLS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-AKT; SIRTUIN 1; SIRTUIN 2;

EID: 84896901019     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.537266     Document Type: Article

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