메뉴 건너뛰기




Volumn 13, Issue 1, 2014, Pages

Engineering Escherichia coli to overproduce aromatic amino acids and derived compounds

Author keywords

Aromatic compounds; Escherichia coli; Metabolic engineering; Phenylalanine; Shikimate pathway; Synthetic biology; Systems biotechnology; Tryptophan; Tyrosine

Indexed keywords

2 PYRONE 4,6 DICARBOXYLIC ACID; 3 (3,4 DIHYDROXYPHENYL)LACTIC ACID; AROMATIC AMINO ACID; AVENANTHRAMIDE DERIVATIVE; CAFFEIC ACID; DELTA TOCOTRIENOL; HYDROXYTYROSOL; NATURAL PRODUCT; PINOCEMBRINE; RESVERATROL; RETICULINE; SHIKIMIC ACID; UNCLASSIFIED DRUG; VIOLACEIN;

EID: 84908134524     PISSN: None     EISSN: 14752859     Source Type: Journal    
DOI: 10.1186/s12934-014-0126-z     Document Type: Review
Times cited : (188)

References (133)
  • 2
    • 36348988805 scopus 로고    scopus 로고
    • Aromatic Amino Acids
    • Springer, Berlin, Heidelberg, Wendisch VF, [Microbiology Monographs]
    • Sprenger G. Aromatic Amino Acids. Amin Acid Biosynth - Pathways, Regul Metab Eng 2007, 418. Springer, Berlin, Heidelberg, Wendisch VF, [Microbiology Monographs, vol. 5].
    • (2007) Amin Acid Biosynth - Pathways, Regul Metab Eng , vol.5 , pp. 418
    • Sprenger, G.1
  • 4
    • 33748857142 scopus 로고    scopus 로고
    • Evolutionary origins of the eukaryotic shikimate pathway: gene fusions, horizontal gene transfer, and endosymbiotic replacements
    • Richards TA, Dacks JB, Campbell SA, Blanchard JL, Foster PG, McLeod R, Roberts CW. Evolutionary origins of the eukaryotic shikimate pathway: gene fusions, horizontal gene transfer, and endosymbiotic replacements. Eukaryot Cell 2006, 5:1517-1531.
    • (2006) Eukaryot Cell , vol.5 , pp. 1517-1531
    • Richards, T.A.1    Dacks, J.B.2    Campbell, S.A.3    Blanchard, J.L.4    Foster, P.G.5    McLeod, R.6    Roberts, C.W.7
  • 6
    • 84867209510 scopus 로고    scopus 로고
    • Systems and synthetic metabolic engineering for amino acid production - the heartbeat of industrial strain development
    • Becker J, Wittmann C. Systems and synthetic metabolic engineering for amino acid production - the heartbeat of industrial strain development. Curr Opin Biotechnol 2012, 23:718-726.
    • (2012) Curr Opin Biotechnol , vol.23 , pp. 718-726
    • Becker, J.1    Wittmann, C.2
  • 7
    • 84871088177 scopus 로고    scopus 로고
    • Amino acid production by Corynebacterium glutamicum
    • Springer Berlin Heidelberg, Berlin, Heidelberg, Yukawa H, Inui M
    • Ikeda M, Takeno S. Amino acid production by Corynebacterium glutamicum. Corynebacterium glutamicum. Volume 23 2013, 107-147. Springer Berlin Heidelberg, Berlin, Heidelberg, Yukawa H, Inui M.
    • (2013) Corynebacterium glutamicum. Volume 23 , pp. 107-147
    • Ikeda, M.1    Takeno, S.2
  • 10
    • 0035209901 scopus 로고    scopus 로고
    • Metabolic engineering for microbial production of aromatic amino acids and derived compounds
    • Bongaerts J, Krämer M, Müller U, Raeven L, Wubbolts M. Metabolic engineering for microbial production of aromatic amino acids and derived compounds. Metab Eng 2001, 3:289-300.
    • (2001) Metab Eng , vol.3 , pp. 289-300
    • Bongaerts, J.1    Krämer, M.2    Müller, U.3    Raeven, L.4    Wubbolts, M.5
  • 11
    • 34547435219 scopus 로고    scopus 로고
    • From scratch to value: Engineering Escherichia coli wild type cells to the production of L-phenylalanine and other fine chemicals derived from chorismate
    • Sprenger GA. From scratch to value: Engineering Escherichia coli wild type cells to the production of L-phenylalanine and other fine chemicals derived from chorismate. Appl Microbiol Biotechnol 2007, 75:739-749.
    • (2007) Appl Microbiol Biotechnol , vol.75 , pp. 739-749
    • Sprenger, G.A.1
  • 12
    • 84908147262 scopus 로고    scopus 로고
    • Biosynthesis of the Aromatic Amino Acids
    • Pittard J, Yang J: Biosynthesis of the Aromatic Amino Acids.Eco Sal Plus 2008, 1.
    • (2008) Eco Sal Plus , pp. 1
    • Pittard, J.1    Yang, J.2
  • 14
    • 65549147541 scopus 로고    scopus 로고
    • Mutagenesis of the bacterial RNA polymerase alpha subunit for improvement of complex phenotypes
    • Klein-Marcuschamer D, Santos CNS, Yu H, Stephanopoulos G. Mutagenesis of the bacterial RNA polymerase alpha subunit for improvement of complex phenotypes. Appl Environ Microbiol 2009, 75:2705-2711.
    • (2009) Appl Environ Microbiol , vol.75 , pp. 2705-2711
    • Klein-Marcuschamer, D.1    Santos, C.N.S.2    Yu, H.3    Stephanopoulos, G.4
  • 15
    • 84882622697 scopus 로고    scopus 로고
    • Genome-scale genetic engineering in Escherichia coli
    • Jeong J, Cho N, Jung D, Bang D. Genome-scale genetic engineering in Escherichia coli. Biotechnol Adv 2013, 31:804-810.
    • (2013) Biotechnol Adv , vol.31 , pp. 804-810
    • Jeong, J.1    Cho, N.2    Jung, D.3    Bang, D.4
  • 17
    • 39549091527 scopus 로고    scopus 로고
    • L-Tyrosine production by recombinant Escherichia coli: Fermentation optimization and recovery
    • Patnaik R, Zolandz RR, Green DA, Kraynie DF. L-Tyrosine production by recombinant Escherichia coli: Fermentation optimization and recovery. Biotechnol Bioeng 2008, 99:741-752.
    • (2008) Biotechnol Bioeng , vol.99 , pp. 741-752
    • Patnaik, R.1    Zolandz, R.R.2    Green, D.A.3    Kraynie, D.F.4
  • 18
    • 0037271033 scopus 로고    scopus 로고
    • Amino acid production processes
    • Springer, Berlin, Heidelberg
    • Ikeda M. Amino acid production processes. Microb Prod L-amino acids 2003, 1-35. Springer, Berlin, Heidelberg.
    • (2003) Microb Prod L-amino acids , pp. 1-35
    • Ikeda, M.1
  • 19
    • 70449715238 scopus 로고    scopus 로고
    • Production of aromatic compounds in bacteria
    • Gosset G. Production of aromatic compounds in bacteria. Curr Opin Biotechnol 2009, 20:651-658.
    • (2009) Curr Opin Biotechnol , vol.20 , pp. 651-658
    • Gosset, G.1
  • 20
    • 5044227742 scopus 로고    scopus 로고
    • The evolution of molecular biology into systems biology
    • Westerhoff HV, Palsson BO. The evolution of molecular biology into systems biology. Nat Biotechnol 2004, 22:1249-1252.
    • (2004) Nat Biotechnol , vol.22 , pp. 1249-1252
    • Westerhoff, H.V.1    Palsson, B.O.2
  • 21
    • 77954699474 scopus 로고    scopus 로고
    • Systems metabolic engineering: Genome-scale models and beyond
    • Blazeck J, Alper H. Systems metabolic engineering: Genome-scale models and beyond. Biotechnol J 2010, 5:647-659.
    • (2010) Biotechnol J , vol.5 , pp. 647-659
    • Blazeck, J.1    Alper, H.2
  • 22
    • 0027291428 scopus 로고
    • Phosphoenolpyruvate:carbohydrate phosphotransferase systems of bacteria
    • Postma PW, Lengeler JW, Jacobson GR. Phosphoenolpyruvate:carbohydrate phosphotransferase systems of bacteria. Microbiol Rev 1993, 57:543-594.
    • (1993) Microbiol Rev , vol.57 , pp. 543-594
    • Postma, P.W.1    Lengeler, J.W.2    Jacobson, G.R.3
  • 23
    • 26844512919 scopus 로고    scopus 로고
    • Improvement ofEscherichia coliproduction strains by modification of the phosphoenolpyruvate: sugar phosphotransferase system
    • Gosset G: Improvement ofEscherichia coliproduction strains by modification of the phosphoenolpyruvate: sugar phosphotransferase system.Microb Cell Fact 2005, 4:14.
    • (2005) Microb Cell Fact , vol.4 , pp. 14
    • Gosset, G.1
  • 24
    • 84867322381 scopus 로고    scopus 로고
    • Current knowledge of the Escherichia coli phosphoenolpyruvate-carbohydrate phosphotransferase system: peculiarities of regulation and impact on growth and product formation
    • Escalante A, Salinas-Cervantes A, Gosset G, Bolívar F. Current knowledge of the Escherichia coli phosphoenolpyruvate-carbohydrate phosphotransferase system: peculiarities of regulation and impact on growth and product formation. Appl Microbiol Biotechnol 2012, 94:1483-1494.
    • (2012) Appl Microbiol Biotechnol , vol.94 , pp. 1483-1494
    • Escalante, A.1    Salinas-Cervantes, A.2    Gosset, G.3    Bolívar, F.4
  • 25
    • 17644375240 scopus 로고    scopus 로고
    • The PEP - pyruvate - oxaloacetate node as the switch point for carbon flux distribution in bacteria
    • Sauer U, Eikmanns BJ. The PEP - pyruvate - oxaloacetate node as the switch point for carbon flux distribution in bacteria. FEMS Microbiol Rev 2005, 29:765-794.
    • (2005) FEMS Microbiol Rev , vol.29 , pp. 765-794
    • Sauer, U.1    Eikmanns, B.J.2
  • 29
    • 0141908155 scopus 로고    scopus 로고
    • Altered glucose transport and shikimate pathway product yields in E. coli
    • Yi J, Draths KM, Li K, Frost JW. Altered glucose transport and shikimate pathway product yields in E. coli. Biotechnol Prog 2003, 19:1450-1459.
    • (2003) Biotechnol Prog , vol.19 , pp. 1450-1459
    • Yi, J.1    Draths, K.M.2    Li, K.3    Frost, J.W.4
  • 31
    • 0029959052 scopus 로고    scopus 로고
    • Pathway engineering for the production of aromatic compounds in Escherichia coli
    • Flores N, Xiao J, Bolivar F, Valle F. Pathway engineering for the production of aromatic compounds in Escherichia coli. Nat Biotechnol 1996, 14:620-623.
    • (1996) Nat Biotechnol , vol.14 , pp. 620-623
    • Flores, N.1    Xiao, J.2    Bolivar, F.3    Valle, F.4
  • 33
    • 84866127855 scopus 로고    scopus 로고
    • Consequences of phosphoenolpyruvate: sugar phosphotranferase system and pyruvate kinase isozymes inactivation in central carbon metabolism flux distribution inEscherichia coli
    • Meza E, Becker J, Bolivar F, Gosset G, Wittmann C: Consequences of phosphoenolpyruvate: sugar phosphotranferase system and pyruvate kinase isozymes inactivation in central carbon metabolism flux distribution inEscherichia coli.Microb Cell Fact 2012, 11:127.
    • (2012) Microb Cell Fact , vol.11 , pp. 127
    • Meza, E.1    Becker, J.2    Bolivar, F.3    Gosset, G.4    Wittmann, C.5
  • 34
    • 84899622651 scopus 로고    scopus 로고
    • Physiological and transcriptional characterization of Escherichia coli strains lacking interconversion of phosphoenolpyruvate and pyruvate when glucose and acetate are coutilized
    • Sabido A, Sigala JC, Hernández-Chávez G, Flores N, Gosset G, Bolívar F. Physiological and transcriptional characterization of Escherichia coli strains lacking interconversion of phosphoenolpyruvate and pyruvate when glucose and acetate are coutilized. Biotechnol Bioeng 2014, 111:1150-1160.
    • (2014) Biotechnol Bioeng , vol.111 , pp. 1150-1160
    • Sabido, A.1    Sigala, J.C.2    Hernández-Chávez, G.3    Flores, N.4    Gosset, G.5    Bolívar, F.6
  • 35
    • 0028036558 scopus 로고
    • Engineering of Escherichia coli central metabolism for aromatic metabolite production with near theoretical yield
    • Patnaik R, Liao JC. Engineering of Escherichia coli central metabolism for aromatic metabolite production with near theoretical yield. Appl Environ Microbiol 1994, 60:3903-3908.
    • (1994) Appl Environ Microbiol , vol.60 , pp. 3903-3908
    • Patnaik, R.1    Liao, J.C.2
  • 37
    • 0036862441 scopus 로고    scopus 로고
    • Modulation of phosphoenolpyruvate synthase expression increases shikimate pathway product yields in E. coli
    • Yi J, Li K, Draths KM, Frost JW. Modulation of phosphoenolpyruvate synthase expression increases shikimate pathway product yields in E. coli. Biotechnol Prog 2002, 18:1141-1148.
    • (2002) Biotechnol Prog , vol.18 , pp. 1141-1148
    • Yi, J.1    Li, K.2    Draths, K.M.3    Frost, J.W.4
  • 38
    • 0030571222 scopus 로고    scopus 로고
    • Pathway analysis, engineering, and physiological considerations for redirecting central metabolism
    • Liao JC, Hou SY, Chao YP. Pathway analysis, engineering, and physiological considerations for redirecting central metabolism. Biotechnol Bioeng 1996, 52:129-140.
    • (1996) Biotechnol Bioeng , vol.52 , pp. 129-140
    • Liao, J.C.1    Hou, S.Y.2    Chao, Y.P.3
  • 40
    • 0034967661 scopus 로고    scopus 로고
    • Disruption of a global regulatory gene to enhance central carbon flux into phenylalanine biosynthesis in Escherichia coli
    • Tatarko M, Romeo T. Disruption of a global regulatory gene to enhance central carbon flux into phenylalanine biosynthesis in Escherichia coli. Curr Microbiol 2001, 43:26-32.
    • (2001) Curr Microbiol , vol.43 , pp. 26-32
    • Tatarko, M.1    Romeo, T.2
  • 42
    • 0028131269 scopus 로고
    • An Escherichia coli K-12 tktA tktB mutant deficient in transketolase activity requires pyridoxine (vitamin B6) as well as the aromatic amino acids and vitamins for growth
    • Zhao G, Winkler ME. An Escherichia coli K-12 tktA tktB mutant deficient in transketolase activity requires pyridoxine (vitamin B6) as well as the aromatic amino acids and vitamins for growth. J Bacteriol 1994, 176:6134-6138.
    • (1994) J Bacteriol , vol.176 , pp. 6134-6138
    • Zhao, G.1    Winkler, M.E.2
  • 45
    • 0029294180 scopus 로고
    • Pathway engineering for production of aromatics in Escherichia coli: confirmation of stoichiometric analysis by independent modulation of AroG, TktA, and Pps activities
    • Patnaik R, Spitzer RG, Liao JC. Pathway engineering for production of aromatics in Escherichia coli: confirmation of stoichiometric analysis by independent modulation of AroG, TktA, and Pps activities. Biotechnol Bioeng 1995, 46:361-370.
    • (1995) Biotechnol Bioeng , vol.46 , pp. 361-370
    • Patnaik, R.1    Spitzer, R.G.2    Liao, J.C.3
  • 46
    • 0035919133 scopus 로고    scopus 로고
    • Determination of 3-deoxy-D-arabino-heptulosonate 7-phosphate productivity and yield from glucose in Escherichia coli devoid of the glucose phosphotransferase transport system
    • Báez JL, Bolívar F, Gosset G. Determination of 3-deoxy-D-arabino-heptulosonate 7-phosphate productivity and yield from glucose in Escherichia coli devoid of the glucose phosphotransferase transport system. Biotechnol Bioeng 2001, 73:530-535.
    • (2001) Biotechnol Bioeng , vol.73 , pp. 530-535
    • Báez, J.L.1    Bolívar, F.2    Gosset, G.3
  • 47
    • 0031013443 scopus 로고    scopus 로고
    • Metabolic engineering and control analysis for production of aromatics: role of transaldolase
    • Lu J, Liao JC. Metabolic engineering and control analysis for production of aromatics: role of transaldolase. Biotechnol Bioeng 1997, 53:132-138.
    • (1997) Biotechnol Bioeng , vol.53 , pp. 132-138
    • Lu, J.1    Liao, J.C.2
  • 48
    • 0025945912 scopus 로고
    • Deletion of pgi alters tryptophan biosynthesis in a genetically engineered strain of Escherichia coli
    • Mascarenhas D, Ashworth DJ, Chen CS. Deletion of pgi alters tryptophan biosynthesis in a genetically engineered strain of Escherichia coli. Appl Environ Microbiol 1991, 57:2995-2999.
    • (1991) Appl Environ Microbiol , vol.57 , pp. 2995-2999
    • Mascarenhas, D.1    Ashworth, D.J.2    Chen, C.S.3
  • 49
    • 80053462862 scopus 로고    scopus 로고
    • NADPH-dependent pgi-gene knockout Escherichia coli metabolism producing shikimate on different carbon sources
    • Ahn J, Chung BKS, Lee D, Park M, Karimi IA, Jung J, Lee H. NADPH-dependent pgi-gene knockout Escherichia coli metabolism producing shikimate on different carbon sources. FEMS Microbiol Lett 2011, 324:10-16.
    • (2011) FEMS Microbiol Lett , vol.324 , pp. 10-16
    • Ahn, J.1    Chung, B.K.S.2    Lee, D.3    Park, M.4    Karimi, I.A.5    Jung, J.6    Lee, H.7
  • 50
    • 84884693506 scopus 로고    scopus 로고
    • Constitutive expression of selected genes from the pentose phosphate and aromatic pathways increases the shikimic acid yield in high-glucose batch cultures of anEscherichia colistrain lacking PTS and pykF
    • Rodriguez A, Martínez JA, Báez-Viveros JL, Flores N, Hernández-Chávez G, Ramírez OT, Gosset G, Bolivar F: Constitutive expression of selected genes from the pentose phosphate and aromatic pathways increases the shikimic acid yield in high-glucose batch cultures of anEscherichia colistrain lacking PTS and pykF.Microb Cell Fact 2013, 12:86.
    • Rodriguez, A.1    Martínez, J.A.2    Báez-Viveros, J.L.3    Flores, N.4    Hernández-Chávez, G.5    Ramírez, O.T.6    Gosset, G.7    Bolivar, F.8
  • 51
    • 0033198744 scopus 로고    scopus 로고
    • Microbial synthesis of 3-dehydroshikimic acid: a comparative analysis of D-xylose, L-arabinose, and D-glucose carbon sources
    • Li K, Frost JW. Microbial synthesis of 3-dehydroshikimic acid: a comparative analysis of D-xylose, L-arabinose, and D-glucose carbon sources. Biotechnol Prog 1999, 15:876-883.
    • (1999) Biotechnol Prog , vol.15 , pp. 876-883
    • Li, K.1    Frost, J.W.2
  • 52
    • 39749112439 scopus 로고    scopus 로고
    • Coutilization of glucose and glycerol enhances the production of aromatic compounds in anEscherichia colistrain lacking the phosphoenolpyruvate: carbohydrate phosphotransferase system
    • Martínez K, De Anda R, Hernández G, Escalante A, Gosset G, Ramírez OT, Bolivar F: Coutilization of glucose and glycerol enhances the production of aromatic compounds in anEscherichia colistrain lacking the phosphoenolpyruvate: carbohydrate phosphotransferase system.Microb Cell Fact 2008, 7:1.
    • (2008) Microb Cell Fact , vol.7 , pp. 1
    • Martínez, K.1    De Anda, R.2    Hernández, G.3    Escalante, A.4    Gosset, G.5    Ramírez, O.T.6    Bolivar, F.7
  • 53
    • 64549158068 scopus 로고    scopus 로고
    • Exploring the effects of carbon sources on the metabolic capacity for shikimic acid production in Escherichia coli using in silico metabolic predictions
    • Ahn JO, Lee HW, Saha R, Park MS, Jung JK, Lee DY. Exploring the effects of carbon sources on the metabolic capacity for shikimic acid production in Escherichia coli using in silico metabolic predictions. J Microbiol Biotechnol 2008, 18:1773-1784.
    • (2008) J Microbiol Biotechnol , vol.18 , pp. 1773-1784
    • Ahn, J.O.1    Lee, H.W.2    Saha, R.3    Park, M.S.4    Jung, J.K.5    Lee, D.Y.6
  • 54
    • 84862310223 scopus 로고    scopus 로고
    • Deletion of the aroK gene is essential for high shikimic acid accumulation through the shikimate pathway in E. coli
    • Chen K, Dou J, Tang S, Yang Y, Wang H, Fang H, Zhou C. Deletion of the aroK gene is essential for high shikimic acid accumulation through the shikimate pathway in E. coli. Bioresour Technol 2012, 119:141-147.
    • (2012) Bioresour Technol , vol.119 , pp. 141-147
    • Chen, K.1    Dou, J.2    Tang, S.3    Yang, Y.4    Wang, H.5    Fang, H.6    Zhou, C.7
  • 55
    • 4344573757 scopus 로고    scopus 로고
    • Metabolic engineering and protein directed evolution increase the yield of L-phenylalanine synthesized from glucose in Escherichia coli
    • Báez-Viveros JL, Osuna J, Hernández-Chávez G, Soberón X, Bolívar F, Gosset G. Metabolic engineering and protein directed evolution increase the yield of L-phenylalanine synthesized from glucose in Escherichia coli. Biotechnol Bioeng 2004, 87:516-524.
    • (2004) Biotechnol Bioeng , vol.87 , pp. 516-524
    • Báez-Viveros, J.L.1    Osuna, J.2    Hernández-Chávez, G.3    Soberón, X.4    Bolívar, F.5    Gosset, G.6
  • 56
    • 84875892911 scopus 로고    scopus 로고
    • Production of L-phenylalanine from glucose by metabolic engineering of wild type Escherichia coli W3110
    • Liu S-P, Xiao M-R, Zhang L, Xu J, Ding Z-Y, Gu Z-H, Shi G-Y. Production of L-phenylalanine from glucose by metabolic engineering of wild type Escherichia coli W3110. Process Biochem 2013, 48:413-419.
    • (2013) Process Biochem , vol.48 , pp. 413-419
    • Liu, S.-P.1    Xiao, M.-R.2    Zhang, L.3    Xu, J.4    Ding, Z.-Y.5    Gu, Z.-H.6    Shi, G.-Y.7
  • 57
    • 44249098772 scopus 로고    scopus 로고
    • Metabolic engineering of Escherichia coli for L-tyrosine production by expression of genes coding for the chorismate mutase domain of the native chorismate mutase-prephenate dehydratase and a cyclohexadienyl dehydrogenase from Zymomonas mobilis
    • Chavez-Bejar MI, Lara AR, Lopez H, Hernandez-Chavez G, Martinez A, Ramirez OT, Bolivar F, Gosset G. Metabolic engineering of Escherichia coli for L-tyrosine production by expression of genes coding for the chorismate mutase domain of the native chorismate mutase-prephenate dehydratase and a cyclohexadienyl dehydrogenase from Zymomonas mobilis. Appl Environ Microbiol 2008, 74:3284-3290.
    • (2008) Appl Environ Microbiol , vol.74 , pp. 3284-3290
    • Chavez-Bejar, M.I.1    Lara, A.R.2    Lopez, H.3    Hernandez-Chavez, G.4    Martinez, A.5    Ramirez, O.T.6    Bolivar, F.7    Gosset, G.8
  • 59
    • 84855188845 scopus 로고    scopus 로고
    • Development of L-tryptophan production strains by defined genetic modification in Escherichia coli
    • Zhao Z-J, Zou C, Zhu Y-X, Dai J, Chen S, Wu D, Wu J, Chen J. Development of L-tryptophan production strains by defined genetic modification in Escherichia coli. J Ind Microbiol Biotechnol 2011, 38:1921-1929.
    • (2011) J Ind Microbiol Biotechnol , vol.38 , pp. 1921-1929
    • Zhao, Z.-J.1    Zou, C.2    Zhu, Y.-X.3    Dai, J.4    Chen, S.5    Wu, D.6    Wu, J.7    Chen, J.8
  • 60
    • 84864960639 scopus 로고    scopus 로고
    • Improved production of tryptophan in genetically engineered Escherichia coli with TktA and PpsA overexpression
    • Shen T, Liu Q, Xie X, Xu Q, Chen N. Improved production of tryptophan in genetically engineered Escherichia coli with TktA and PpsA overexpression. J Biomed Biotechnol 2012, 2012:1-8.
    • (2012) J Biomed Biotechnol , vol.2012 , pp. 1-8
    • Shen, T.1    Liu, Q.2    Xie, X.3    Xu, Q.4    Chen, N.5
  • 61
  • 63
    • 0027772102 scopus 로고
    • Identification and removal of impediments to biocatalytic synthesis of aromatics from D-Glucose: rate-limiting enzymes in the common pathway of aromatic amino acid biosynthesis
    • Dell KA, Frost JW. Identification and removal of impediments to biocatalytic synthesis of aromatics from D-Glucose: rate-limiting enzymes in the common pathway of aromatic amino acid biosynthesis. J Am Chem Soc 1993, 115:11581-11589.
    • (1993) J Am Chem Soc , vol.115 , pp. 11581-11589
    • Dell, K.A.1    Frost, J.W.2
  • 65
    • 10044287191 scopus 로고    scopus 로고
    • Stimulation, monitoring, and analysis of pathway dynamics by metabolic profiling in the aromatic amino acid pathway
    • Oldiges M, Kunze M, Degenring D, Sprenger GA, Takors R. Stimulation, monitoring, and analysis of pathway dynamics by metabolic profiling in the aromatic amino acid pathway. Biotechnol Prog 2004, 20:1623-1633.
    • (2004) Biotechnol Prog , vol.20 , pp. 1623-1633
    • Oldiges, M.1    Kunze, M.2    Degenring, D.3    Sprenger, G.A.4    Takors, R.5
  • 66
    • 77950649821 scopus 로고    scopus 로고
    • Metabolic engineering for the production of shikimic acid in an evolvedEscherichia colistrain lacking the phosphoenolpyruvate: carbohydrate phosphotransferase system
    • Escalante A, Calderón R, Valdivia A, De Anda R, Hernández G, Ramírez OT, Gosset G, Bolívar F: Metabolic engineering for the production of shikimic acid in an evolvedEscherichia colistrain lacking the phosphoenolpyruvate: carbohydrate phosphotransferase system.Microb Cell Fact 2010, 9:21.
    • (2010) Microb Cell Fact , vol.9 , pp. 21
    • Escalante, A.1    Calderón, R.2    Valdivia, A.3    De Anda, R.4    Hernández, G.5    Ramírez, O.T.6    Gosset, G.7    Bolívar, F.8
  • 67
    • 32044431846 scopus 로고    scopus 로고
    • Feedback inhibition of chorismate mutase/prephenate dehydrogenase (TyrA) of Escherichia coli: Generation and characterization of tyrosine-insensitive mutants
    • Lutke-Eversloh T, Stephanopoulos G. Feedback inhibition of chorismate mutase/prephenate dehydrogenase (TyrA) of Escherichia coli: Generation and characterization of tyrosine-insensitive mutants. Appl Environ Microbiol 2005, 71:7224-7228.
    • (2005) Appl Environ Microbiol , vol.71 , pp. 7224-7228
    • Lutke-Eversloh, T.1    Stephanopoulos, G.2
  • 68
    • 84893649889 scopus 로고    scopus 로고
    • Production of shikimic acid fromEscherichia colithrough chemically inducible chromosomal evolution and cofactor metabolic engineering
    • Cui Y-Y, Ling C, Zhang Y-Y, Huang J, Liu J-Z: Production of shikimic acid fromEscherichia colithrough chemically inducible chromosomal evolution and cofactor metabolic engineering.Microb Cell Fact 2014, 13:21.
    • (2014) Microb Cell Fact , vol.13 , pp. 21
    • Cui, Y.-Y.1    Ling, C.2    Zhang, Y.-Y.3    Huang, J.4    Liu, J.-Z.5
  • 69
    • 29544436147 scopus 로고    scopus 로고
    • Shikimic acid production by a modified strain of E. coli (W3110.shik1) under phosphate-limited and carbon-limited conditions
    • Johansson L, Lindskog A, Silfversparre G, Cimander C, Nielsen KF, Lidén G. Shikimic acid production by a modified strain of E. coli (W3110.shik1) under phosphate-limited and carbon-limited conditions. Biotechnol Bioeng 2005, 92:541-552.
    • (2005) Biotechnol Bioeng , vol.92 , pp. 541-552
    • Johansson, L.1    Lindskog, A.2    Silfversparre, G.3    Cimander, C.4    Nielsen, K.F.5    Lidén, G.6
  • 70
    • 84901805933 scopus 로고    scopus 로고
    • Metabolic engineering of Escherichia coli for improving shikimate synthesis from glucose
    • Chen X, Li M, Zhou L, Shen W, Algasan G, Fan Y, Wang Z. Metabolic engineering of Escherichia coli for improving shikimate synthesis from glucose. Bioresour Technol 2014, 166:64-71.
    • (2014) Bioresour Technol , vol.166 , pp. 64-71
    • Chen, X.1    Li, M.2    Zhou, L.3    Shen, W.4    Algasan, G.5    Fan, Y.6    Wang, Z.7
  • 72
    • 84877742688 scopus 로고    scopus 로고
    • Expanding horizons of shikimic acid: Recent progresses in production and its endless frontiers in application and market trends
    • Rawat G, Tripathi P, Saxena RK. Expanding horizons of shikimic acid: Recent progresses in production and its endless frontiers in application and market trends. Appl Microbiol Biotechnol 2013, 97:4277-4287.
    • (2013) Appl Microbiol Biotechnol , vol.97 , pp. 4277-4287
    • Rawat, G.1    Tripathi, P.2    Saxena, R.K.3
  • 73
    • 84892365772 scopus 로고    scopus 로고
    • Fermentative production of shikimic acid: a paradigm shift of production concept from plant route to microbial route
    • Tripathi P, Rawat G, Yadav S, Saxena RK. Fermentative production of shikimic acid: a paradigm shift of production concept from plant route to microbial route. Bioprocess Biosyst Eng 2013, 36:1665-1673.
    • (2013) Bioprocess Biosyst Eng , vol.36 , pp. 1665-1673
    • Tripathi, P.1    Rawat, G.2    Yadav, S.3    Saxena, R.K.4
  • 74
    • 84873179221 scopus 로고    scopus 로고
    • A short overview on the medicinal chemistry of (-)-shikimic acid
    • Estevez A, Estevez R. A short overview on the medicinal chemistry of (-)-shikimic acid. Mini Rev Med Chem 2012, 12:1443-1454.
    • (2012) Mini Rev Med Chem , vol.12 , pp. 1443-1454
    • Estevez, A.1    Estevez, R.2
  • 77
    • 77954537042 scopus 로고    scopus 로고
    • Construction of an L-phenylalanine-producing tyrosine-prototrophic Escherichia coli strain using tyrA ssrA-like tagged alleles
    • Doroshenko VG, Shakulov RS, Kazakova SM, Kivero AD, Yampolskaya TA, Mashko SV. Construction of an L-phenylalanine-producing tyrosine-prototrophic Escherichia coli strain using tyrA ssrA-like tagged alleles. Biotechnol Lett 2010, 32:1117-1121.
    • (2010) Biotechnol Lett , vol.32 , pp. 1117-1121
    • Doroshenko, V.G.1    Shakulov, R.S.2    Kazakova, S.M.3    Kivero, A.D.4    Yampolskaya, T.A.5    Mashko, S.V.6
  • 79
    • 84862806969 scopus 로고    scopus 로고
    • Modification of tryptophan transport system and its impact on production of L-tryptophan in Escherichia coli
    • Liu Q, Cheng Y, Xie X, Xu Q, Chen N. Modification of tryptophan transport system and its impact on production of L-tryptophan in Escherichia coli. Bioresour Technol 2012, 114:549-554.
    • (2012) Bioresour Technol , vol.114 , pp. 549-554
    • Liu, Q.1    Cheng, Y.2    Xie, X.3    Xu, Q.4    Chen, N.5
  • 80
    • 84880507415 scopus 로고    scopus 로고
    • Knocking out analysis of tryptophan permeases in Escherichia coli for improving L-tryptophan production
    • Gu P, Yang F, Li F, Liang Q, Qi Q. Knocking out analysis of tryptophan permeases in Escherichia coli for improving L-tryptophan production. Appl Microbiol Biotechnol 2013, 97:6677-6683.
    • (2013) Appl Microbiol Biotechnol , vol.97 , pp. 6677-6683
    • Gu, P.1    Yang, F.2    Li, F.3    Liang, Q.4    Qi, Q.5
  • 81
    • 84857679736 scopus 로고    scopus 로고
    • One-step of tryptophan attenuator inactivation and promoter swapping to improve the production of L-tryptophan inEscherichia coli
    • Gu P, Yang F, Kang J, Wang Q, Qi Q: One-step of tryptophan attenuator inactivation and promoter swapping to improve the production of L-tryptophan inEscherichia coli.Microb Cell Fact 2012, 11:30.
    • (2012) Microb Cell Fact , vol.11 , pp. 30
    • Gu, P.1    Yang, F.2    Kang, J.3    Wang, Q.4    Qi, Q.5
  • 83
    • 84866285573 scopus 로고    scopus 로고
    • Production of aromatic compounds by metabolically engineered Escherichia coli with an expanded shikimate pathway
    • Koma D, Yamanaka H, Moriyoshi K, Ohmoto T, Sakai K. Production of aromatic compounds by metabolically engineered Escherichia coli with an expanded shikimate pathway. Appl Environ Microbiol 2012, 78:6203-6216.
    • (2012) Appl Environ Microbiol , vol.78 , pp. 6203-6216
    • Koma, D.1    Yamanaka, H.2    Moriyoshi, K.3    Ohmoto, T.4    Sakai, K.5
  • 85
    • 80052688691 scopus 로고    scopus 로고
    • Metabolic engineering of the L-phenylalanine pathway inEscherichia colifor the production of S- or R-mandelic acid
    • Sun Z, Ning Y, Liu L, Liu Y, Sun B, Jiang W, Yang C, Yang S: Metabolic engineering of the L-phenylalanine pathway inEscherichia colifor the production of S- or R-mandelic acid.Microb Cell Fact 2011, 10:71.
    • (2011) Microb Cell Fact , vol.10 , pp. 71
    • Sun, Z.1    Ning, Y.2    Liu, L.3    Liu, Y.4    Sun, B.5    Jiang, W.6    Yang, C.7    Yang, S.8
  • 86
    • 85027913894 scopus 로고    scopus 로고
    • Systems metabolic engineering of Escherichia coli for gram scale production of the antitumor drug deoxyviolacein from glycerol
    • Rodrigues AL, Becker J, De Souza Lima AO, Porto LM, Wittmann C. Systems metabolic engineering of Escherichia coli for gram scale production of the antitumor drug deoxyviolacein from glycerol. Biotechnol Bioeng 2014, 20:1-31.
    • (2014) Biotechnol Bioeng , vol.20 , pp. 1-31
    • Rodrigues, A.L.1    Becker, J.2    De Souza Lima, A.O.3    Porto, L.M.4    Wittmann, C.5
  • 89
    • 84859776015 scopus 로고    scopus 로고
    • Synthetic biology: New strategies for directing design
    • Lynch SA, Gill RT. Synthetic biology: New strategies for directing design. Metab Eng 2012, 14:205-211.
    • (2012) Metab Eng , vol.14 , pp. 205-211
    • Lynch, S.A.1    Gill, R.T.2
  • 90
    • 84886096327 scopus 로고    scopus 로고
    • Challenges and opportunities in synthetic biology for chemical engineers
    • Luo Y, Lee J-K, Zhao H. Challenges and opportunities in synthetic biology for chemical engineers. Chem Eng Sci 2013, 103:115-119.
    • (2013) Chem Eng Sci , vol.103 , pp. 115-119
    • Luo, Y.1    Lee, J.-K.2    Zhao, H.3
  • 91
    • 84859768457 scopus 로고    scopus 로고
    • Parts plus pipes: Synthetic biology approaches to metabolic engineering
    • Boyle PM, Silver PA. Parts plus pipes: Synthetic biology approaches to metabolic engineering. Metab Eng 2012, 14:223-232.
    • (2012) Metab Eng , vol.14 , pp. 223-232
    • Boyle, P.M.1    Silver, P.A.2
  • 92
    • 84859776222 scopus 로고    scopus 로고
    • The future of metabolic engineering and synthetic biology: Towards a systematic practice
    • Yadav VG, De Mey M, Giaw Lim C, Kumaran Ajikumar P, Stephanopoulos G. The future of metabolic engineering and synthetic biology: Towards a systematic practice. Metab Eng 2012, 14:233-241.
    • (2012) Metab Eng , vol.14 , pp. 233-241
    • Yadav, V.G.1    De Mey, M.2    Giaw Lim, C.3    Kumaran Ajikumar, P.4    Stephanopoulos, G.5
  • 93
    • 39849084210 scopus 로고    scopus 로고
    • Combinatorial pathway analysis for improved L-tyrosine production in Escherichia coli: identification of enzymatic bottlenecks by systematic gene overexpression
    • Lütke-Eversloh T, Stephanopoulos G. Combinatorial pathway analysis for improved L-tyrosine production in Escherichia coli: identification of enzymatic bottlenecks by systematic gene overexpression. Metab Eng 2008, 10:69-77.
    • (2008) Metab Eng , vol.10 , pp. 69-77
    • Lütke-Eversloh, T.1    Stephanopoulos, G.2
  • 94
    • 84880677911 scopus 로고    scopus 로고
    • Metabolic engineering of Escherichia coli for production of salvianic acid A via an artificial biosynthetic pathway
    • Yao Y-F, Wang C-S, Qiao J, Zhao G-R. Metabolic engineering of Escherichia coli for production of salvianic acid A via an artificial biosynthetic pathway. Metab Eng 2013, 19:79-87.
    • (2013) Metab Eng , vol.19 , pp. 79-87
    • Yao, Y.-F.1    Wang, C.-S.2    Qiao, J.3    Zhao, G.-R.4
  • 96
    • 84875261923 scopus 로고    scopus 로고
    • Towards the in vivo production of tocotrienol compounds: engineering of a plasmid-free Escherichia coli strain for the heterologous synthesis of 2-methyl-6-geranylgeranyl-benzoquinol
    • Ghanegaonkar S, Conrad J, Beifuss U, Sprenger GA, Albermann C. Towards the in vivo production of tocotrienol compounds: engineering of a plasmid-free Escherichia coli strain for the heterologous synthesis of 2-methyl-6-geranylgeranyl-benzoquinol. J Biotechnol 2012, 164:238-247.
    • (2012) J Biotechnol , vol.164 , pp. 238-247
    • Ghanegaonkar, S.1    Conrad, J.2    Beifuss, U.3    Sprenger, G.A.4    Albermann, C.5
  • 98
    • 84872221971 scopus 로고    scopus 로고
    • Metabolic engineering of Escherichia coli for (2S)-pinocembrin production from glucose by a modular metabolic strategy
    • Wu J, Du G, Zhou J, Chen J. Metabolic engineering of Escherichia coli for (2S)-pinocembrin production from glucose by a modular metabolic strategy. Metab Eng 2013, 16:48-55.
    • (2013) Metab Eng , vol.16 , pp. 48-55
    • Wu, J.1    Du, G.2    Zhou, J.3    Chen, J.4
  • 99
    • 84883232076 scopus 로고    scopus 로고
    • Multivariate modular metabolic engineering of Escherichia coli to produce resveratrol from L-tyrosine
    • Wu J, Liu P, Fan Y, Bao H, Du G, Zhou J, Chen J. Multivariate modular metabolic engineering of Escherichia coli to produce resveratrol from L-tyrosine. J Biotechnol 2013, 167:404-411.
    • (2013) J Biotechnol , vol.167 , pp. 404-411
    • Wu, J.1    Liu, P.2    Fan, Y.3    Bao, H.4    Du, G.5    Zhou, J.6    Chen, J.7
  • 101
    • 84865281539 scopus 로고    scopus 로고
    • Rational, combinatorial, and genomic approaches for engineering L-tyrosine production in Escherichia coli
    • Santos CNS, Xiao W, Stephanopoulos G. Rational, combinatorial, and genomic approaches for engineering L-tyrosine production in Escherichia coli. Proc Natl Acad Sci 2012, 109:13538-13543.
    • (2012) Proc Natl Acad Sci , vol.109 , pp. 13538-13543
    • Santos, C.N.S.1    Xiao, W.2    Stephanopoulos, G.3
  • 102
    • 33847083318 scopus 로고    scopus 로고
    • Global transcription machinery engineering: A new approach for improving cellular phenotype
    • Alper H, Stephanopoulos G. Global transcription machinery engineering: A new approach for improving cellular phenotype. Metab Eng 2007, 9:258-267.
    • (2007) Metab Eng , vol.9 , pp. 258-267
    • Alper, H.1    Stephanopoulos, G.2
  • 103
    • 84870293949 scopus 로고    scopus 로고
    • Artificial biosynthesis of phenylpropanoic acids in a tyrosine overproducingEscherichia coli strain
    • Kang S-Y, Choi O, Lee JK, Hwang BY, Uhm T-B, Hong Y-S: Artificial biosynthesis of phenylpropanoic acids in a tyrosine overproducingEscherichia coli strain.Microb Cell Fact 2012, 11:153.
    • (2012) Microb Cell Fact , vol.11 , pp. 153
    • Kang, S.-Y.1    Choi, O.2    Lee, J.K.3    Hwang, B.Y.4    Uhm, T.-B.5    Hong, Y.-S.6
  • 104
    • 84876676603 scopus 로고    scopus 로고
    • Engineering E. coli for caffeic acid biosynthesis from renewable sugars
    • Zhang H, Stephanopoulos G. Engineering E. coli for caffeic acid biosynthesis from renewable sugars. Appl Microbiol Biotechnol 2013, 97:3333-3341.
    • (2013) Appl Microbiol Biotechnol , vol.97 , pp. 3333-3341
    • Zhang, H.1    Stephanopoulos, G.2
  • 105
    • 84886239741 scopus 로고    scopus 로고
    • Caffeic acid production enhancement by engineering a phenylalanine over-producing Escherichia coli strain
    • Huang Q, Lin Y, Yan Y. Caffeic acid production enhancement by engineering a phenylalanine over-producing Escherichia coli strain. Biotechnol Bioeng 2013, 110:3188-3196.
    • (2013) Biotechnol Bioeng , vol.110 , pp. 3188-3196
    • Huang, Q.1    Lin, Y.2    Yan, Y.3
  • 106
    • 84869020402 scopus 로고    scopus 로고
    • Engineering of L-tyrosine oxidation in Escherichia coli and microbial production of hydroxytyrosol
    • Satoh Y, Tajima K, Munekata M, Keasling JD, Lee TS. Engineering of L-tyrosine oxidation in Escherichia coli and microbial production of hydroxytyrosol. Metab Eng 2012, 14:603-610.
    • (2012) Metab Eng , vol.14 , pp. 603-610
    • Satoh, Y.1    Tajima, K.2    Munekata, M.3    Keasling, J.D.4    Lee, T.S.5
  • 110
    • 84873596341 scopus 로고    scopus 로고
    • Metabolic engineering of Escherichia coli using synthetic small regulatory RNAs
    • Na D, Yoo SM, Chung H, Park H, Park JH, Lee SY. Metabolic engineering of Escherichia coli using synthetic small regulatory RNAs. Nat Biotechnol 2013, 31:170-174.
    • (2013) Nat Biotechnol , vol.31 , pp. 170-174
    • Na, D.1    Yoo, S.M.2    Chung, H.3    Park, H.4    Park, J.H.5    Lee, S.Y.6
  • 111
    • 67651083634 scopus 로고    scopus 로고
    • Toward systematic metabolic engineering based on the analysis of metabolic regulation by the integration of different levels of information
    • Shimizu K. Toward systematic metabolic engineering based on the analysis of metabolic regulation by the integration of different levels of information. Biochem Eng J 2009, 46:235-251.
    • (2009) Biochem Eng J , vol.46 , pp. 235-251
    • Shimizu, K.1
  • 112
    • 3242726864 scopus 로고    scopus 로고
    • Impact of " ome" analyses on inverse metabolic engineering
    • Bro C, Nielsen J. Impact of " ome" analyses on inverse metabolic engineering. Metab Eng 2004, 6:204-211.
    • (2004) Metab Eng , vol.6 , pp. 204-211
    • Bro, C.1    Nielsen, J.2
  • 113
    • 47249096975 scopus 로고    scopus 로고
    • Application of systems biology for bioprocess development
    • Park JH, Lee SY, Kim TY, Kim HU. Application of systems biology for bioprocess development. Trends Biotechnol 2008, 26:404-412.
    • (2008) Trends Biotechnol , vol.26 , pp. 404-412
    • Park, J.H.1    Lee, S.Y.2    Kim, T.Y.3    Kim, H.U.4
  • 114
    • 53049087092 scopus 로고    scopus 로고
    • Towards systems metabolic engineering of microorganisms for amino acid production
    • Park JH, Lee SY. Towards systems metabolic engineering of microorganisms for amino acid production. Curr Opin Biotechnol 2008, 19:454-460.
    • (2008) Curr Opin Biotechnol , vol.19 , pp. 454-460
    • Park, J.H.1    Lee, S.Y.2
  • 115
    • 80052802581 scopus 로고    scopus 로고
    • Comparative 13C metabolic flux analysis of pyruvate dehydrogenase complex-deficient, L-valine-producing Corynebacterium glutamicum
    • Bartek T, Blombach B, Lang S, Eikmanns BJ, Wiechert W, Oldiges M, Nöh K, Noack S. Comparative 13C metabolic flux analysis of pyruvate dehydrogenase complex-deficient, L-valine-producing Corynebacterium glutamicum. Appl Environ Microbiol 2011, 77:6644-6652.
    • (2011) Appl Environ Microbiol , vol.77 , pp. 6644-6652
    • Bartek, T.1    Blombach, B.2    Lang, S.3    Eikmanns, B.J.4    Wiechert, W.5    Oldiges, M.6    Nöh, K.7    Noack, S.8
  • 116
    • 79952106791 scopus 로고    scopus 로고
    • From zero to hero - Design-based systems metabolic engineering of Corynebacterium glutamicum for L-lysine production
    • Becker J, Zelder O, Häfner S, Schröder H, Wittmann C. From zero to hero - Design-based systems metabolic engineering of Corynebacterium glutamicum for L-lysine production. Metab Eng 2011, 13:159-168.
    • (2011) Metab Eng , vol.13 , pp. 159-168
    • Becker, J.1    Zelder, O.2    Häfner, S.3    Schröder, H.4    Wittmann, C.5
  • 117
    • 84862689750 scopus 로고    scopus 로고
    • Improved L-lysine production with Corynebacterium glutamicum and systemic insight into citrate synthase flux and activity
    • Van Ooyen J, Noack S, Bott M, Reth A, Eggeling L. Improved L-lysine production with Corynebacterium glutamicum and systemic insight into citrate synthase flux and activity. Biotechnol Bioeng 2012, 109:2070-2081.
    • (2012) Biotechnol Bioeng , vol.109 , pp. 2070-2081
    • Van Ooyen, J.1    Noack, S.2    Bott, M.3    Reth, A.4    Eggeling, L.5
  • 119
    • 34447122580 scopus 로고    scopus 로고
    • Proteomic investigation on the pyk-F gene knockout Escherichia coli for aromatic amino acid production
    • Kedar P, Colah R, Shimizu K. Proteomic investigation on the pyk-F gene knockout Escherichia coli for aromatic amino acid production. Enzyme Microb Technol 2007, 41:455-465.
    • (2007) Enzyme Microb Technol , vol.41 , pp. 455-465
    • Kedar, P.1    Colah, R.2    Shimizu, K.3
  • 120
    • 18944394722 scopus 로고    scopus 로고
    • The global gene expression response of Escherichia coli to L-phenylalanine
    • Polen T, Krämer M, Bongaerts J, Wubbolts M, Wendisch VF. The global gene expression response of Escherichia coli to L-phenylalanine. J Biotechnol 2005, 115:221-237.
    • (2005) J Biotechnol , vol.115 , pp. 221-237
    • Polen, T.1    Krämer, M.2    Bongaerts, J.3    Wubbolts, M.4    Wendisch, V.F.5
  • 121
    • 84898599172 scopus 로고    scopus 로고
    • Global transcriptomic analysis of an engineeredEscherichia colistrain lacking the phosphoenolpyruvate: carbohydrate phosphotransferase system during shikimic acid production in rich culture medium
    • Cortés-Tolalpa L, Gutiérrez-Ríos RM, Martínez LM, De Anda R, Gosset G, Bolívar F, Escalante A: Global transcriptomic analysis of an engineeredEscherichia colistrain lacking the phosphoenolpyruvate: carbohydrate phosphotransferase system during shikimic acid production in rich culture medium.Microb Cell Fact 2014, 13:28.
    • (2014) Microb Cell Fact , vol.13 , pp. 28
    • Cortés-Tolalpa, L.1    Gutiérrez-Ríos, R.M.2    Martínez, L.M.3    De Anda, R.4    Gosset, G.5    Bolívar, F.6    Escalante, A.7
  • 122
    • 33750351855 scopus 로고    scopus 로고
    • Transcriptome analysis of a shikimic acid producing strain of Escherichia coli W3110 grown under carbon- and phosphate-limited conditions
    • Johansson L, Lidén G. Transcriptome analysis of a shikimic acid producing strain of Escherichia coli W3110 grown under carbon- and phosphate-limited conditions. J Biotechnol 2006, 126:528-545.
    • (2006) J Biotechnol , vol.126 , pp. 528-545
    • Johansson, L.1    Lidén, G.2
  • 124
    • 60849129806 scopus 로고    scopus 로고
    • Genome-scale analysis to the impact of gene deletion on the metabolism ofE. coli: constraint-based simulation approach
    • Xu Z, Sun X, Yu S: Genome-scale analysis to the impact of gene deletion on the metabolism ofE. coli: constraint-based simulation approach.BMC Bioinformatics 2009, 10(Suppl 1):S62.
    • (2009) BMC Bioinformatics , vol.10 , pp. S62
    • Xu, Z.1    Sun, X.2    Yu, S.3
  • 125
    • 70149091494 scopus 로고    scopus 로고
    • Ensemble modeling for aromatic production inEscherichia coli
    • Rizk ML, Liao JC: Ensemble modeling for aromatic production inEscherichia coli.PLoS One 2009, 4:e6903.
    • (2009) PLoS One , vol.4 , pp. e6903
    • Rizk, M.L.1    Liao, J.C.2
  • 126
    • 84862167117 scopus 로고    scopus 로고
    • Scale-up of microbial processes: Impacts, tools and open questions
    • Takors R. Scale-up of microbial processes: Impacts, tools and open questions. J Biotechnol 2012, 160:3-9.
    • (2012) J Biotechnol , vol.160 , pp. 3-9
    • Takors, R.1
  • 127
    • 33846885651 scopus 로고    scopus 로고
    • Living with heterogeneities in bioreactors. Understanding the effects of environmental gradients on cells
    • Lara AR, Galindo E, Ramirez OT, Palomares LA. Living with heterogeneities in bioreactors. Understanding the effects of environmental gradients on cells. Mol Biotechnol 2006, 34:355-381.
    • (2006) Mol Biotechnol , vol.34 , pp. 355-381
    • Lara, A.R.1    Galindo, E.2    Ramirez, O.T.3    Palomares, L.A.4
  • 128
    • 79961189026 scopus 로고    scopus 로고
    • An industrial perspective on bioreactor scale-down: What we can learn from combined large-scale bioprocess and model fluid studies
    • Noorman H. An industrial perspective on bioreactor scale-down: What we can learn from combined large-scale bioprocess and model fluid studies. Biotechnol J 2011, 6:934-943.
    • (2011) Biotechnol J , vol.6 , pp. 934-943
    • Noorman, H.1
  • 129
    • 84893783152 scopus 로고    scopus 로고
    • Fermentation characterization of an L-tryptophan producing Escherichia coli strain with inactivated phosphotransacetylase
    • Wang J, Huang J, Shi J, Xu Q, Xie X, Chen N. Fermentation characterization of an L-tryptophan producing Escherichia coli strain with inactivated phosphotransacetylase. Ann Microbiol 2013, 63:1219-1224.
    • (2013) Ann Microbiol , vol.63 , pp. 1219-1224
    • Wang, J.1    Huang, J.2    Shi, J.3    Xu, Q.4    Xie, X.5    Chen, N.6
  • 131
    • 84891475027 scopus 로고    scopus 로고
    • Fed-batch production of L-phenylalanine from glycerol and ammonia with recombinant Escherichia coli
    • Weiner M, Albermann C, Gottlieb K, Sprenger GA, Weuster-Botz D. Fed-batch production of L-phenylalanine from glycerol and ammonia with recombinant Escherichia coli. Biochem Eng J 2014, 83:62-69.
    • (2014) Biochem Eng J , vol.83 , pp. 62-69
    • Weiner, M.1    Albermann, C.2    Gottlieb, K.3    Sprenger, G.A.4    Weuster-Botz, D.5
  • 133
    • 58149263251 scopus 로고    scopus 로고
    • Bioconversion of phenylpyruvic acid to L-phenylalanine by mixed-gel immobilization of Escherichia coli EP8-10
    • Hu Y, Tang T, Yang W, Zhou H. Bioconversion of phenylpyruvic acid to L-phenylalanine by mixed-gel immobilization of Escherichia coli EP8-10. Process Biochem 2009, 44:142-145.
    • (2009) Process Biochem , vol.44 , pp. 142-145
    • Hu, Y.1    Tang, T.2    Yang, W.3    Zhou, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.