Metabolic engineering of Escherichia coli for improving l-3,4-dihydroxyphenylalanine (l-DOPA) synthesis from glucose

Journal of Industrial Microbiology and Biotechnology

Volumn 38, Issue 11, 2011, Pages 1845-1852

  Muñoz, Ana Joyce ^a   Hernández Chávez, Georgina ^a   De Anda, Ramon ^a   Martínez, Alfredo ^a   Bolívar, Francisco ^a   Gosset, Guillermo ^a  

^a INSTITUTO DE BIOTECNOLOGÍA   (Mexico)

Author keywords

Aromatics; E. coli; l DOPA; l tyrosine; Phosphotransferase system; TyrR transcriptional dual regulator

Indexed keywords

3 DEOXY DEXTRO ARABINO HEPTULOSONATE 7 PHOSPHATE SYNTHASE; 4 HYDROXYPHENYLACETATE 3 HYDROXYLASE; BACTERIAL PROTEIN; CARBON; CHORISMATE MUTASE; CYCLOHEXADIENYL DEHYDROGENASE; GLUCOSE; HPABC PROTEIN; LEVODOPA; PHOSPHOENOLPYRUVATE; PHOSPHOTRANSFERASE; PREPHENATE HYDRATASE; REGULATOR PROTEIN; REGULATORY PROTEIN TYRR; TRANSKETOLASE; UNCLASSIFIED DRUG;

AMINO ACID SYNTHESIS; ARTICLE; BACTERIAL GENE; BACTERIAL METABOLISM; BACTERIAL STRAIN; BATCH FERMENTATION; CONTROLLED STUDY; CULTURE MEDIUM; ESCHERICHIA COLI; GENE EXPRESSION; GENETIC CODE; GLUCONEOGENESIS; GLUCOSE TRANSPORT SYSTEM; METABOLIC ENGINEERING; NEGATIVE FEEDBACK; NONHUMAN; PHENOTYPE; PHOSPHOENOLPYRUVATE PHOSPHOTRANSFERASE SYSTEM; PROTEIN DOMAIN; TRANSCRIPTION REGULATION; ZYMOMONAS MOBILIS;

3-DEOXY-7-PHOSPHOHEPTULONATE SYNTHASE; CHORISMATE MUTASE; ESCHERICHIA COLI; GLUCOSE; LEVODOPA; METABOLIC ENGINEERING; MIXED FUNCTION OXYGENASES; PHOSPHOENOLPYRUVATE SUGAR PHOSPHOTRANSFERASE SYSTEM; PLASMIDS; PREPHENATE DEHYDRATASE; PREPHENATE DEHYDROGENASE; TRANSKETOLASE; TYROSINE; ZYMOMONAS;

ESCHERICHIA COLI; ZYMOMONAS MOBILIS;

EID: 80855132889     PISSN: 13675435     EISSN: 14765535     Source Type: Journal    
DOI: 10.1007/s10295-011-0973-0     Document Type: Article

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