메뉴 건너뛰기




Volumn 52, Issue 1, 1996, Pages 129-140

Pathway analysis, engineering, and physiological considerations for redirecting central metabolism

Author keywords

aromatic amino acid; central metabolism; Escherichia coli; pathway engineering; phosphoenolpyruvate carboxykinase; phosphoenolpyruvate synthase

Indexed keywords

AMINO ACIDS; AROMATIC COMPOUNDS; BIOSYNTHESIS; CARBOHYDRATES; COLIFORM BACTERIA; ENZYME KINETICS; ENZYMES; GENETIC ENGINEERING; GLUCOSE; METABOLITES; PHYSIOLOGY; STOICHIOMETRY;

EID: 0030571222     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0290(19961005)52:1<129::AID-BIT13>3.0.CO;2-J     Document Type: Conference Paper
Times cited : (164)

References (50)
  • 1
    • 0027319272 scopus 로고
    • Regulation of the Escherichia coli heat-shock response
    • Bukau, B. 1993. Regulation of the Escherichia coli heat-shock response. Mol. Microbiol. 9: 671-680.
    • (1993) Mol. Microbiol. , vol.9 , pp. 671-680
    • Bukau, B.1
  • 4
    • 0025967766 scopus 로고
    • Is hsp70 the cellular thermometer?
    • Craig, E. A., Gross, C. A. 1991. Is hsp70 the cellular thermometer? TIBS 16: 135-140.
    • (1991) TIBS , vol.16 , pp. 135-140
    • Craig, E.A.1    Gross, C.A.2
  • 5
    • 0027300506 scopus 로고
    • Heat shock proteins: Molecular chaperones of protein biogenesis
    • Craig, E. A., Gambill, B. D., Nelson, R. J. 1993. Heat shock proteins: Molecular chaperones of protein biogenesis. Microbiol. Rev. 57: 402-414.
    • (1993) Microbiol. Rev. , vol.57 , pp. 402-414
    • Craig, E.A.1    Gambill, B.D.2    Nelson, R.J.3
  • 6
    • 0026338108 scopus 로고
    • Effect of alteration of the acetic acid synthesis pathway on the fermentation pattern of Escherichia coli
    • Diaz-Ricci, J. C., Regan, L., Bailey, J. E. 1991. Effect of alteration of the acetic acid synthesis pathway on the fermentation pattern of Escherichia coli. Biotechnol. Bioeng. 38: 1318-1324.
    • (1991) Biotechnol. Bioeng. , vol.38 , pp. 1318-1324
    • Diaz-Ricci, J.C.1    Regan, L.2    Bailey, J.E.3
  • 8
    • 0018183277 scopus 로고
    • Cascade control of Escherichia coli glutamine synthetase. II. Metabolite regulation of the enzymes in the cascade
    • Engleman, E. G., Francis, S. H. 1978. Cascade control of Escherichia coli glutamine synthetase. II. Metabolite regulation of the enzymes in the cascade. Arch. Biochem. Biophys. 191: 602-612.
    • (1978) Arch. Biochem. Biophys. , vol.191 , pp. 602-612
    • Engleman, E.G.1    Francis, S.H.2
  • 9
    • 0026662751 scopus 로고
    • Role of phosphorylated metabolic intermediates in the regulation of glutamine synthetase synthesis in Escherichia coli
    • Feng, J., Atkinson, M. R., McCleary, W., Stock, J. B., Wanner, B. L., Ninfa, A. J. 1992. Role of phosphorylated metabolic intermediates in the regulation of glutamine synthetase synthesis in Escherichia coli. J. Bacteriol. 174: 6061-6070.
    • (1992) J. Bacteriol. , vol.174 , pp. 6061-6070
    • Feng, J.1    Atkinson, M.R.2    McCleary, W.3    Stock, J.B.4    Wanner, B.L.5    Ninfa, A.J.6
  • 13
    • 0011064770 scopus 로고
    • Products of nitrogen regulatory genes ntrA and ntrC of enteric bacteria activate glnA transcription in vitro: Evidence that the ntrA product is a s factor
    • Hirschman, J., Wong, P. K. Sei, K., Keener, J., Kustu, S. 1985. Products of nitrogen regulatory genes ntrA and ntrC of enteric bacteria activate glnA transcription in vitro: Evidence that the ntrA product is a s factor. Proc. Natl. Acad. Sci. USA 82: 7525-7529.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 7525-7529
    • Hirschman, J.1    Wong, P.K.2    Sei, K.3    Keener, J.4    Kustu, S.5
  • 14
    • 0028913643 scopus 로고
    • A mutant phosphoenolpyruvate carboxykinase in Escherichia coli conferring oxaloaceter decarboxylase activity
    • Hou, S. Y., Chao, Y. P., Liao, J. C. 1995. A mutant phosphoenolpyruvate carboxykinase in Escherichia coli conferring oxaloaceter decarboxylase activity. J. Bacteriol. 177: 1620-1623.
    • (1995) J. Bacteriol. , vol.177 , pp. 1620-1623
    • Hou, S.Y.1    Chao, Y.P.2    Liao, J.C.3
  • 15
    • 0024051671 scopus 로고
    • Heat shock protein GroE of Escherichia coli: Key protective roles against thermal stress
    • Kusukawa, N., Yura, T. 1988. Heat shock protein GroE of Escherichia coli: Key protective roles against thermal stress. Genes Develop. 2: 874-882.
    • (1988) Genes Develop. , vol.2 , pp. 874-882
    • Kusukawa, N.1    Yura, T.2
  • 16
    • 0028686612 scopus 로고
    • Flux adaptations of citrate synthase-deficient Escherichia coli
    • Lee, J., Goel, A., Ataai, M. M., Domach, M. M. 1994. Flux adaptations of citrate synthase-deficient Escherichia coli. Ann. N.Y. Acad. Sci. 745: 35-50.
    • (1994) Ann. N.Y. Acad. Sci. , vol.745 , pp. 35-50
    • Lee, J.1    Goel, A.2    Ataai, M.M.3    Domach, M.M.4
  • 17
    • 10144238589 scopus 로고
    • Some practical issues in metabolic pathway engineering
    • Paper 29b, abstract
    • Liao, J. C. 1989. Some practical issues in metabolic pathway engineering. AIChE annual meeting. Paper 29b, abstract.
    • (1989) AIChE Annual Meeting
    • Liao, J.C.1
  • 18
    • 0028686682 scopus 로고
    • Alteration of the biochemical valves in central metabolism of Escherichia coli
    • Liao, J. C., Chao, Y. P., Patnaik, R. 1994. Alteration of the biochemical valves in central metabolism of Escherichia coli. Ann. N.Y. Acad. Sci. 745: 21-34.
    • (1994) Ann. N.Y. Acad. Sci. , vol.745 , pp. 21-34
    • Liao, J.C.1    Chao, Y.P.2    Patnaik, R.3
  • 19
    • 0015147278 scopus 로고
    • The effect of carbon and nitrogen sources on the level of metabolic intermediates in Escherichia coli
    • Lowry, O. H., Carter, J., Wood, J. B., Glaser, L. 1971. The effect of carbon and nitrogen sources on the level of metabolic intermediates in Escherichia coli. J. Biol. Chem. 246: 6511-6521.
    • (1971) J. Biol. Chem. , vol.246 , pp. 6511-6521
    • Lowry, O.H.1    Carter, J.2    Wood, J.B.3    Glaser, L.4
  • 20
    • 0027207516 scopus 로고
    • Is acetyl phosphate a global signal in Escherichia coli?
    • McCleary, W. R., Stock, J. B., Ninfa, A. J. 1993. Is acetyl phosphate a global signal in Escherichia coli? J. Bacteriol. 175: 2793-2798.
    • (1993) J. Bacteriol. , vol.175 , pp. 2793-2798
    • McCleary, W.R.1    Stock, J.B.2    Ninfa, A.J.3
  • 21
    • 0002645855 scopus 로고
    • Regulation of carbon and nitrogen utilization
    • F. C. Neidhardt, J, L. Ingraham, K. B. Low, B. Magasanik, M. Schaechter, and H. E. Umbarger (eds.), ASM, Washington, DC
    • Magasanik, B., Neidhardt, F C. 1987. Regulation of carbon and nitrogen utilization, pp. 1318-1325. In: F. C. Neidhardt, J, L. Ingraham, K. B. Low, B. Magasanik, M. Schaechter, and H. E. Umbarger (eds.), Escherichia coli and Salmonella typhimurium. ASM, Washington, DC.
    • (1987) Escherichia Coli and Salmonella Typhimurium , pp. 1318-1325
    • Magasanik, B.1    Neidhardt, F.C.2
  • 22
    • 0025405421 scopus 로고
    • Simple constrained-optimization view of acetate overflow in Escherichia coli
    • Majewski, R. A., Domach, M. M. 1990. Simple constrained-optimization view of acetate overflow in Escherichia coli. Biotechnol. Bioeng. 35: 732-738.
    • (1990) Biotechnol. Bioeng. , vol.35 , pp. 732-738
    • Majewski, R.A.1    Domach, M.M.2
  • 23
    • 0019812276 scopus 로고
    • Role of gene fadR in Escherichia coli acetate metabolism
    • Maloy, S. R., Nunn, W. D. 1995. Role of gene fadR in Escherichia coli acetate metabolism. J. Bacteriol. 148: 83-90.
    • (1995) J. Bacteriol. , vol.148 , pp. 83-90
    • Maloy, S.R.1    Nunn, W.D.2
  • 24
    • 0025945912 scopus 로고
    • Deletion of pgi alters tryptophan biosynthesis in a genetically engineered strain of escherichia coli
    • Mascarenhas, D., Ashworth, D. J., Chen, C. S. 1991. Deletion of pgi alters tryptophan biosynthesis in a genetically engineered strain of escherichia coli. Appl. Env. Microbiol. 57: 2995-2999.
    • (1991) Appl. Env. Microbiol. , vol.57 , pp. 2995-2999
    • Mascarenhas, D.1    Ashworth, D.J.2    Chen, C.S.3
  • 25
    • 0019890564 scopus 로고
    • Positive regulatory gene for temperature-controlled proteins in Escherichia coli
    • Neidhardt, F. C., VanBogelen, R. A. 1981. Positive regulatory gene for temperature-controlled proteins in Escherichia coli. Biochem. Biophys. Res. Commun. 100: 894-900.
    • (1981) Biochem. Biophys. Res. Commun. , vol.100 , pp. 894-900
    • Neidhardt, F.C.1    Vanbogelen, R.A.2
  • 27
    • 0028036558 scopus 로고
    • Engineering of Escherichia coli central metabolism for aromatic metabolite production with near theoretical yield
    • Patnaik, R., Liao, J. C. 1994. Engineering of Escherichia coli central metabolism for aromatic metabolite production with near theoretical yield. Appl. Env. Microbiol. 60: 3903-3908.
    • (1994) Appl. Env. Microbiol. , vol.60 , pp. 3903-3908
    • Patnaik, R.1    Liao, J.C.2
  • 28
    • 0026460088 scopus 로고
    • Stimulation of glucose catabolism in Escherichia coli by a potential futile cycle
    • Patnaik, R., Roof, W. D., Young, R. F., Liao, J. C. 1992. Stimulation of glucose catabolism in Escherichia coli by a potential futile cycle. J. Bacteriol. 174: 7527-7532.
    • (1992) J. Bacteriol. , vol.174 , pp. 7527-7532
    • Patnaik, R.1    Roof, W.D.2    Young, R.F.3    Liao, J.C.4
  • 29
    • 0029294180 scopus 로고
    • Pathway engineering for production of aromatics in Escherichia coli: Confirmation of stoichiometric analysis by independent modulation of AroG, TktA, and Pps activities
    • Patnaik, R., Spitzer, R. G., Liao, J. C. 1995. Pathway engineering for production of aromatics in Escherichia coli: Confirmation of stoichiometric analysis by independent modulation of AroG, TktA, and Pps activities. Biotechnol. Bioeng. 46: 361-370.
    • (1995) Biotechnol. Bioeng. , vol.46 , pp. 361-370
    • Patnaik, R.1    Spitzer, R.G.2    Liao, J.C.3
  • 30
    • 10144245333 scopus 로고
    • Enzyme II of the phosphotransferase system: Transport and regulation
    • A. Torriani-Gorini, E. Yagil, and S. Silver, (eds.), ASM, Washington, DC
    • Postma, P. W., van der Vlag, J., de Waard, J. H., Yap, W. M. G. J., van Dam, K., Ruijter, G. J. G. 1994. Enzyme II of the phosphotransferase system: Transport and regulation, pp. 169-174. In: A. Torriani-Gorini, E. Yagil, and S. Silver, (eds.), Phosphate in microorganisms. ASM, Washington, DC.
    • (1994) Phosphate in Microorganisms , pp. 169-174
    • Postma, P.W.1    Van Der Vlag, J.2    De Waard, J.H.3    Yap, W.M.G.J.4    Van Dam, K.5    Ruijter, G.J.G.6
  • 32
    • 0021864787 scopus 로고
    • Expression of glnA in Escherichia coli is regulated at tandem promoters
    • Reitzer, L. J., Magasanik, B. 1983. Expression of glnA in Escherichia coli is regulated at tandem promoters. Proc. Natl. Acad. Sci. USA 82: 1979-1983.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 1979-1983
    • Reitzer, L.J.1    Magasanik, B.2
  • 33
    • 0000060736 scopus 로고
    • Ammonia assimilation and the biosynthesis of glutamine, glutamate, aspartate, asparagine, L-alanine, and D-alanine
    • F. C. Neidhardt, J. L. Ingraham, K. B. Low, B. Magasanik, M. Schaechter, and H. E. Umbarger (eds), ASM, Washington, DC
    • Reitzer, L. J., Magasanik, B. 1987. Ammonia assimilation and the biosynthesis of glutamine, glutamate, aspartate, asparagine, L-alanine, and D-alanine. pp. 302-320. In: F. C. Neidhardt, J. L. Ingraham, K. B. Low, B. Magasanik, M. Schaechter, and H. E. Umbarger (eds), Escherichia coli and Salmonella typhimurium. ASM, Washington, DC.
    • (1987) Escherichia Coli and Salmonella Typhimurium , pp. 302-320
    • Reitzer, L.J.1    Magasanik, B.2
  • 34
    • 0026059292 scopus 로고
    • Glc of the phosphoenolpyruvate-dependent phosphotransferase system in Escherichia coli
    • Glc of the phosphoenolpyruvate-dependent phosphotransferase system in Escherichia coli. J. Bacteriol. 173: 6184-6191.
    • (1991) J. Bacteriol. , vol.173 , pp. 6184-6191
    • Ruijter, G.J.G.1    Postma, P.W.2    Van Dam, K.3
  • 35
    • 0001657582 scopus 로고
    • Energetics of the bacterial phosphotransferase system in sugar transport and regulation of carbon metabolism
    • T. A. Krulwich (ed.), Academic, New York
    • Saier, M. H. Jr., Chin, A. M. 1990. Energetics of the bacterial phosphotransferase system in sugar transport and regulation of carbon metabolism, pp. 273-294. In: T. A. Krulwich (ed.), The bacteria, Vol XII: Bacterial energetics. Academic, New York.
    • (1990) The Bacteria, Vol XII: Bacterial Energetics , vol.12 , pp. 273-294
    • Saier Jr., M.H.1    Chin, A.M.2
  • 36
    • 0027537642 scopus 로고
    • Refined algorithm and computer program for calculating all nonnegative fluxes admissible in steady states of biochemical reaction systems with or without some flux rates fixed
    • Schuster, R., Schuster, S. 1993. Refined algorithm and computer program for calculating all nonnegative fluxes admissible in steady states of biochemical reaction systems with or without some flux rates fixed. Comp. Appl. Biosci. 9: 79-85.
    • (1993) Comp. Appl. Biosci. , vol.9 , pp. 79-85
    • Schuster, R.1    Schuster, S.2
  • 37
    • 0022971582 scopus 로고
    • MPS: An algorithm and data base for metabolic pathway synthesis
    • Seressiotis, A., Bailey, J. E. 1986. MPS: An algorithm and data base for metabolic pathway synthesis. Biotechnol. Lett. 8: 837-842.
    • (1986) Biotechnol. Lett. , vol.8 , pp. 837-842
    • Seressiotis, A.1    Bailey, J.E.2
  • 38
    • 0025302283 scopus 로고
    • Use of regulated cell lysis in a lethal genetic selection in Escherichia coli: Identification of the autoinducer-binding region of the LuxR protein from Vibrio fischeri ATCC 7744
    • Shadel, G. S., Young, R., Baldwin, T. O. 1990. Use of regulated cell lysis in a lethal genetic selection in Escherichia coli: Identification of the autoinducer-binding region of the LuxR protein from Vibrio fischeri ATCC 7744. J. Bacteriol. 172: 3980-3987.
    • (1990) J. Bacteriol. , vol.172 , pp. 3980-3987
    • Shadel, G.S.1    Young, R.2    Baldwin, T.O.3
  • 39
    • 0001037354 scopus 로고
    • 2-Keto-3-deoxy-D-araboheptonic acid 7-phosphate synthetase
    • Srinivasan, P. R., Sprinson, D. B. 1958. 2-Keto-3-deoxy-D-araboheptonic acid 7-phosphate synthetase. J. Biol. Chem. 234: 716-722.
    • (1958) J. Biol. Chem. , vol.234 , pp. 716-722
    • Srinivasan, P.R.1    Sprinson, D.B.2
  • 40
    • 0025866296 scopus 로고
    • Network rigidity and metabolic engineering in metabolite overproduction
    • Stephanopoulos, G., Vallino, J. J. 1991. Network rigidity and metabolic engineering in metabolite overproduction. Science 252:1675-1681.
    • (1991) Science , vol.252 , pp. 1675-1681
    • Stephanopoulos, G.1    Vallino, J.J.2
  • 41
    • 0024398149 scopus 로고
    • Protein phosphorylation and regulation of adaptive response in bacteria
    • Stock, J. B., Ninfa, A. J., Stock, A. M. 1989. Protein phosphorylation and regulation of adaptive response in bacteria. Microbiol. Rev. 53: 450-490.
    • (1989) Microbiol. Rev. , vol.53 , pp. 450-490
    • Stock, J.B.1    Ninfa, A.J.2    Stock, A.M.3
  • 44
    • 0024854864 scopus 로고
    • 32 is reduced under conditions of excess heat shock protein production in Escherichia coli
    • 32 is reduced under conditions of excess heat shock protein production in Escherichia coli. Genes Devel. 3: 2003-2010.
    • (1989) Genes Devel. , vol.3 , pp. 2003-2010
    • Straus, D.B.1    Walter, W.A.2    Gross, C.A.3
  • 45
    • 0025035371 scopus 로고
    • DNA-looping and enhancer activity: Association between DNA-bound NtrC activator and RNA polymerase at the bacterial glnA promoter
    • Su, W., Porter, S., Kustu, S., Echols, H. 1990. DNA-looping and enhancer activity: Association between DNA-bound NtrC activator and RNA polymerase at the bacterial glnA promoter. Proc. Natl. Acad. Sci. USA 87: 5504-5508.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 5504-5508
    • Su, W.1    Porter, S.2    Kustu, S.3    Echols, H.4
  • 47
    • 0021172220 scopus 로고
    • Identification and regulation of the glnL operator-promoter of the complex glnALG operon of Escherichia coli
    • Ueno-Nishio, S., Mango, S., Reitzer, L. J., Magasanik, B. 1984. Identification and regulation of the glnL operator-promoter of the complex glnALG operon of Escherichia coli. J. Bacteriol. 160: 379-384.
    • (1984) J. Bacteriol. , vol.160 , pp. 379-384
    • Ueno-Nishio, S.1    Mango, S.2    Reitzer, L.J.3    Magasanik, B.4
  • 48
    • 0027223982 scopus 로고
    • Stoichiometric interpretation of Escherichia coli glucose catabolism under various oxygen rates
    • Varma, A., Boesch, B. W., Palsson, B. O. 1993. Stoichiometric interpretation of Escherichia coli glucose catabolism under various oxygen rates. Appl. Env. Microbiol. 59: 2465-2473.
    • (1993) Appl. Env. Microbiol. , vol.59 , pp. 2465-2473
    • Varma, A.1    Boesch, B.W.2    Palsson, B.O.3
  • 49
    • 0020479946 scopus 로고
    • Sugar transport by the bacterial phosphotransferase system. XIV. Phosphoryl transfer reactions catalyzed by enzyme I of Salmonella typhimurium
    • Weigel, N., Kukuruzinska, M. A., Nakazawa, A., Waygood, E. B., Roseman, S. 1982. Sugar transport by the bacterial phosphotransferase system. XIV. Phosphoryl transfer reactions catalyzed by enzyme I of Salmonella typhimurium. J. Biol. Chem. 257: 14477-14491.
    • (1982) J. Biol. Chem. , vol.257 , pp. 14477-14491
    • Weigel, N.1    Kukuruzinska, M.A.2    Nakazawa, A.3    Waygood, E.B.4    Roseman, S.5
  • 50
    • 0020092887 scopus 로고
    • Genetic control of heat-shock protein synthesis and its bearing on growth and thermal resistance in Escherichia coli
    • Yamamori, T., Yura, T. 1982. Genetic control of heat-shock protein synthesis and its bearing on growth and thermal resistance in Escherichia coli. Proc. Natl. Acad. Sci. USA 79: 860-864.
    • (1982) Proc. Natl. Acad. Sci. USA , vol.79 , pp. 860-864
    • Yamamori, T.1    Yura, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.