Deletion of the aroK gene is essential for high shikimic acid accumulation through the shikimate pathway in E. coli

Bioresource Technology

Volumn 119, Issue , 2012, Pages 141-147

  Chen, Kai ^a   Dou, Jie ^a   Tang, Shirui ^a   Yang, Yishun ^a   Wang, Hui ^a   Fang, Hongqing ^b   Zhou, Changlin ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

Author keywords

Antisense RNA interference; Arok gene; Gene deletion; Shikimate kinase

Indexed keywords

ANTISENSE RNA; CHROMOSOMAL DELETIONS; COMMERCIAL APPLICATIONS; E. COLI; FLASK CULTIVATION; GENE DELETION; GENE INACTIVATION; METABOLIC INTERMEDIATES; SHIKIMATE KINASE; SHIKIMATE PATHWAY; SHIKIMIC ACIDS;

CARBOXYLIC ACIDS; ENZYMES; ESCHERICHIA COLI; RNA; STRAIN;

GENES;

SHIKIMIC ACID;

BIOACCUMULATION; BIOCHEMISTRY; CHROMOSOME; COLIFORM BACTERIUM; CULTIVATION; ENZYME ACTIVITY; FERMENTATION; GENE EXPRESSION; GENETIC ENGINEERING; METABOLITE;

AROK GENE; ARTICLE; BACTERIAL STRAIN; CHROMOSOME DELETION; CONTROLLED STUDY; ESCHERICHIA COLI; FERMENTATION; GENE; GENE DELETION; GENE INACTIVATION; NONHUMAN; PRIORITY JOURNAL; RNA INTERFERENCE;

ESCHERICHIA COLI; GENETIC ENHANCEMENT; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); RNA INTERFERENCE; SHIKIMIC ACID; SIGNAL TRANSDUCTION; UP-REGULATION;

ESCHERICHIA COLI;

EID: 84862310223     PISSN: 09608524     EISSN: 18732976     Source Type: Journal    
DOI: 10.1016/j.biortech.2012.05.100     Document Type: Article

References (29)

1. Adachi O., Ano Y., Toyama H., Matsushita K. High shikimate production from quinate with two enzymatic systems of acetic acid bacteria. Biosci. Biothec. Biochem. 2006, 70:2579-2582.
2. Ahn J.O., Lee H.W., Saha R., Park M.S., Jung J.K., Lee D.Y. Exploring the effects of carbon sources on the metabolic capacity for shikimic acid production in Escherichia coli using in silico metabolic predictions. J. Microbial. Biotechnol. 2008, 18:1773-1784.
3. Bok S.H., Demain A.L. An improved colorimetric assay for polyols. Anal. Biochem. 1977, 81:18-20.
4. Chandran S.S., Yi J., Draths K.M., von Daeniken R., Weber W., Frost J.W. Phosphoenolpyruvate availability and the biosynthesis of shikimic acid. Biotechnol. Prog. 2003, 19:808-814.
5. Datsenko K.A., Wanner B.L. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. PNAS 2000, 97:6640-6645.
6. Dean D.A., Reizer J., Nikaido H., Saier M.H. Regulation of the maltose transport system of Escherichia coli by the glucose-specific enzyme III of the phosphoenolpyruvate-sugar phosphotransferase system. J. Biol. Chem. 1990, 265:21005-21010.
7. Defeyter R.C., Pittard J. Genetic and molecular analysis of aroL, the gene for shikimate kinase II in Escherichia coli K-12. J. Bacteriology 1986, 165:226-232.
8. De Clercq E. Strategies in the design of antiviral drugs. Nat. Rev. Drug Discov. 2002, 1:13-25.
9. Draths K.M., Knop D.R., Frost J.W. Shikimic acid and quinic acid: replacing isolation from plant sources with recombinant microbial biocatalysis. J. Am. Chem. Soc. 1999, 12:1603-1604.
10. Escalante A., Calderón R., Valdvia A., Anda R., Hernández G., Ramírez O.T., Gosset G., Bolívar F. Metabolic engineering for the production of shikimic acid in an evolved Escherichia coli strain lacking the phosphoenolpyruvate: carbohydrate phosphotransferase system. Microbial. Cell Factories 2010, 9:21.
11. Gibson J.M., Thomas J.D., Barker J.L., Chandran S.S., Harrup M.K., Draths K.M., Frost J.W. Benzene-free synthesis of phenol. Angewandte. Chemie. 2001, 113:1999-2002.
12. Haslam E. Shikimic Acid: Metabolism and Metabolites 1993, Wiley & sons, New York.
13. Jiang, S., Singh, G., Boam, D.J., Coggins, J.R., 1999. Synthesis of 3-deoxy-3, 3-difluoroshikimic acid and its 4-epimer from quinic acid. Tetrahedron Asymetry 10, 4087-4090.
14. Johansson L., Lidén G. Transcriptome analysis of a shikimic acid producing strain of Escherichia coli W3110 grown under carbon- and phosphate-limited conditions. J. Biotechnol. 2006, 126:528-545.
15. Johansson L., Lindskog A., Silfversparre G., Cimander C., Nielsen K.F., Lidén G. Shikimic acid production by a modified strain of E. coli (w3110.shik1) under phosphate-limited and carbon-limited conditions. Biotechnol. Bioeng. 2005, 92:541-552.
16. Knop D.R., Draths K.M., Chandran S.S., Barker J.L., Daeniken R.V., Weber W., Frost J.W. Hydroaromatic equilibration during biosyhthesis of shikimic acid. J. Am. Chem. Soc. 2001, 123:10173-10182.
17. Krämer M., Bongaerts J., Bovenberg R., Kremer S., Muller U., Orf S., Wubbolts M., Raeven L. Metabolic engineering for microbial production of shikimic acid. Metab. Eng. 2003, 5:277-283.
18. Martínez K., Anda R., Hernández G., Escalante A., Gosset G., Ramírez O.T., Bolívar F.G. Coutilization of glucose and glycerol enhances the production of aromatic compounds in an Escherichia coli strain lacking the phosphoenolpyruvate: carbohydrate phosphotransferase system. Microbial. Cell Factories 2008, 7:1.
19. Michel G., Roszak A.W., Sauvé V., Maclean J., Matte A., Coggins J.R., Cygler M., Lapthorn A.J. Structures of shikimate dehydrogenase AroE and its paralog YdiB: a common structural framework for different activities. J. Biol. Chem. 2003, 278:19463-19472.
20. Patnaik R., Liao J.C. Engineering of Escherichia coli central metabolism for aromatic metabolite production with near theoretical yield. Appl. Environ. Microbiol. 1994, 60:3903-3908.
21. Patnaik R., Spitzer R., Liao J.C. Pathway engineering for production of aromatics in Escherichia coli: confirmation of stoichiometric analysis by independent modulation of AroG, TktA, and Pps activities. Biotechnol. Bioeng. 1995, 46:361-370.
22. Pittard J., Wallace B.J. Gene controlling the uptake of shikimic acid by Escherichia coli. J. Bacteriol. 1966, 92:1070-1075.
23. Russell R.J., Lesley F., Haire L.F., Stevens D.J., Collins P.J., Lin Y.P., Blackburn G.M., Hay A.J., Gamblin S.J., Skehel J.J. The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design. Nature 2006, 443:45-49.
24. Song C., Jiang S., Singh G. Syntheses of (6S)-6-fluoro- and (6R)-6-hydoxyshikimic acids. Tetrahedron Lett. 2001, 42:9069-9071.
25. Yi J., Draths K.M., Frost J.W. Altered glucose transport and shikimate pathway product yields in E. coli. Biotechnol. Prog. 2003, 19:1450-1459.
26. Yi J., Li K., Draths K.M., Frost J.W. Modulation of phosphoenolpyruvate systhase expression increases shikimate pathway product yields in E. coli. Biotechnol. Prog. 2002, 18:1141-1148.
27. wt. Bioresour. Technol. 2010, 101:4151-4156.
28. Zhou J.Z., Zou Y.K., Dai H.M., Li S.L., Cai Y.F., Fang H.Q. One-step knockout of the ptsHIcrr operon in Escherichia coli and characterization of the mutant. Microbiol. China 2010, 37:1146-1152.
29. Zou Y.K., Zhou J.Z., Sun X., Cai Y.F., Dai H.M., Li S.L., Zhou C.L., Fang H.Q. Construction of shikimic acid-producing engineered Escherichia coli strains based on ptsHIcrr mutants. Microbiol. China 2011, 38:1186-1192.