Towards the in vivo production of tocotrienol compounds: Engineering of a plasmid-free Escherichia coli strain for the heterologous synthesis of 2-methyl-6-geranylgeranyl-benzoquinol

Journal of Biotechnology

Volumn 164, Issue 2, 2012, Pages 238-247

  Ghanegaonkar, Shashank ^a   Conrad, Jürgen ^b   Beifuss, Uwe ^b   Sprenger, Georg A ^a   Albermann, Christoph ^a  

^a UNIVERSITY OF STUTTGART   (Germany)

^b UNIVERSITY OF HOHENHEIM   (Germany)

Author keywords

2 Methyl 6 geranylgeranyl benzoquinone; Chromosomal integration; Tocotrienol biosynthesis; Vitamin E

Indexed keywords

BENZOQUINONES; BIOSYNTHESIS GENES; CHROMOSOMAL INTEGRATION; EFFICIENT SYNTHESIS; EXPRESSION LEVELS; RECOMBINANT E. COLI; TOCOTRIENOLS; VITAMIN-E;

BIOCHEMISTRY; BIOSYNTHESIS; CHROMOSOMES; DNA; GENE EXPRESSION; STRAIN;

ESCHERICHIA COLI;

2 METHYL 6 GERANYLGERANYL BENZOQUINOL; ALPHA TOCOTRIENOL; DEOXY XYLULOSE; ISOPENTENYL DIPHOSPHATE DELTA ISOMERASE; UNCLASSIFIED DRUG; XYLULOSE;

ARTICLE; BACTERIAL CELL; BACTERIAL CHROMOSOME; BACTERIAL GROWTH; BACTERIAL MEMBRANE; BACTERIAL STRAIN; CELL ISOLATION; CONTROLLED STUDY; ENZYME ACTIVITY; ESCHERICHIA COLI; GENE EXPRESSION; GENE SYNTHESIS; IN VIVO STUDY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

BIOREACTORS; CLONING, MOLECULAR; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ESCHERICHIA COLI; GENETIC ENGINEERING; HYDROQUINONES; METABOLIC NETWORKS AND PATHWAYS; TOCOTRIENOLS;

EID: 84875261923     PISSN: 01681656     EISSN: 18734863     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2012.08.010     Document Type: Article

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