Modular engineering of L-tyrosine production in Escherichia coli

Applied and Environmental Microbiology

Volumn 78, Issue 1, 2012, Pages 89-98

  Juminaga, Darmawi ^a,b   Baidoo, Edward E K ^b   Redding Johanson, Alyssa M ^b   Batth, Tanveer S ^b   Burd, Helcio ^b   Mukhopadhyay, Aindrila ^b,c   Petzold, Christopher J ^b,c   Keasling, Jay D ^a,b,c,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b JOINT BIOENERGY INSTITUTE   (United States)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^d University of California at Berkeley   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIFUNCTIONAL ACTIVITY; BIOLOGICAL PRODUCTION; BIOSYNTHETIC PATHWAY; CODON USAGE; COPY NUMBER; DEHYDROQUINATE; E. COLI; L-TYROSINE; METABOLIC PATHWAYS; METABOLITE PROFILING; PARALOGS; PHOSPHOENOLPYRUVATES; PROMOTER STRENGTH; PROTEOMICS; SHIKIMATE KINASE; SHIKIMATES; SIDE PRODUCTS; SYNTHASES; THEORETICAL YIELD;

BIOCHEMISTRY; BIOMOLECULES; BIOSYNTHESIS; ENZYMES; ESCHERICHIA COLI; GENE EXPRESSION; GLUCOSE; METABOLISM; METABOLITES; OPTIMIZATION;

AMINO ACIDS;

ALCOHOL DEHYDROGENASE; ERYTHROSE 4 PHOSPHATE; ERYTHROSE 4-PHOSPHATE; ESCHERICHIA COLI PROTEIN; GLUCOSE; PHOSPHOENOLPYRUVATE; PHOSPHOTRANSFERASE; SHIKIMATE DEHYDROGENASE; SHIKIMATE KINASE; SUGAR PHOSPHATE; TYROSINE;

BIOLOGICAL PRODUCTION; COLIFORM BACTERIUM; ENZYME ACTIVITY; GLUCOSE; METABOLITE; OPTIMIZATION; PHOSPHATE; PLASMID; PROTEOMICS;

ARTICLE; BIOSYNTHESIS; ESCHERICHIA COLI; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLIC ENGINEERING; METABOLISM; METHODOLOGY; POLYMERASE CHAIN REACTION; PROTEOMICS;

ALCOHOL OXIDOREDUCTASES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GLUCOSE; METABOLIC ENGINEERING; PHOSPHOENOLPYRUVATE; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); POLYMERASE CHAIN REACTION; PROTEOMICS; SUGAR PHOSPHATES; TYROSINE;

ESCHERICHIA COLI;

EID: 84855694523     PISSN: 00992240     EISSN: 10985336     Source Type: Journal    
DOI: 10.1128/AEM.06017-11     Document Type: Article

References (48)

1. Ahn JO, et al. 2008. Exploring the effects of carbon sources on the metabolic capacity for shikimic acid production in Escherichia coli using in silico metabolic predictions. J. Microbiol. Biotechnol. 18:1773-1784.
2. Ajikumar PK, et al. 2010. Isoprenoid pathway optimization for Taxol precursor overproduction in Escherichia coli. Science 330:70-74.
3. Anderson JC, et al. 2010. BglBricks: a flexible standard for biological part assembly. J. Biol. Eng. 4:1.
4. Bongaerts J, Kramer M, Muller U, Raeven L, Wubbolts M. 2001. Metabolic engineering for microbial production of aromatic amino acids and derived compounds. Metab. Eng. 3:289-300.
5. Chaudhuri S, Coggins JR. 1985. The purification of shikimate dehydrogenase from Escherichia coli. Biochem. J. 226:217-223.
6. Chavez-Bejar MI, et al. 2008. Metabolic engineering of Escherichia coli for L-tyrosine production by expression of genes coding for the chorismate mutase domain of the native chorismate mutase-prephenate dehydratase and a cyclohexadienyl dehydrogenase from Zymomonas mobilis. Appl. Environ. Microbiol. 74:3284-3290.
7. Dell KA, Frost JW. 1993. Identification and removal of impediments to biocatalytic synthesis of aromatics from D-glucose: rate-limiting enzymes in the common pathway of aromatic amino acid biosynthesis. J. Am. Chem. Soc. 115:11581-11589.
8. Dosselaere F, Vanderleyden J. 2001. A metabolic node in action: chorismate-utilizing enzymes in microorganisms. Crit. Rev. Microbiol. 27:75-131.
9. Draths KM, et al. 1992. Biocatalytic synthesis of aromatics from D-glucose- the role of transketolase. J. Am. Chem. Soc. 114:3956-3962.
10. Duncan K, Chaudhuri S, Campbell MS, Coggins JR. 1986. The overexpression and complete amino acid sequence of Escherichia coli 3-dehydroquinase. Biochem. J. 238:475-483.
11. Eudes A, et al. 2011. Production of tranilast [N-(3',4'-dimethoxycinnamoyl)-anthranilic acid] and its analogs in yeast Saccharomyces cerevisiae. Appl. Microbiol. Biotechnol. 89:989-1000.
12. Gavini N, Pulakat L. 1991. Role of translation of the pheA leader peptide coding region in attenuation regulation of the Escherichia coli pheA gene. J. Bacteriol. 173:4904-4907.
13. Gosset G. 2009. Production of aromatic compounds in bacteria. Curr. Opin. Biotechnol. 20:651-658.
14. Herrmann KM, Weaver LM. 1999. The shikimate pathway. Annu. Rev. Plant Physiol. Plant Mol. Biol. 50:473-503.
15. Horton RM, Hunt HD, Ho SN, Pullen JK, Pease LR. 1989. Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension. Gene 77:61-68.
16. Humphreys DP, et al. 2000. High-level periplasmic expression in Escherichia coli using a eukaryotic signal peptide: importance of codon usage at the 5' end of the coding sequence. Protein Expr. Purif. 20:252-264.
17. Ikeda M. 2006. Towards bacterial strains overproducing L-tryptophan and other aromatics by metabolic engineering. Appl. Microbiol. Biotechnol. 69:615-626.
18. Knop DR, et al. 2001. Hydroaromatic equilibration during biosynthesis of shikimic acid. J. Am. Chem. Soc. 123:10173-10182.
19. Kramer M, et al. 2003. Metabolic engineering for microbial production of shikimic acid. Metab. Eng. 5:277-283.
20. Lee SK, Keasling JD. 2005. A propionate-inducible expression system for enteric bacteria. Appl. Environ. Microbiol. 71:6856-6862.
21. Leuchtenberger W, Huthmacher K, Drauz K. 2005. Biotechnological production of amino acids and derivatives: current status and prospects. Appl. Microbiol. Biotechnol. 69:1-8.
22. Li K, Frost JW. 1999. Microbial synthesis of 3-dehydroshikimic acid: a comparative analysis of D-xylose, L-arabinose, and D-glucose carbon sources. Biotechnol. Prog. 15:876-883.
23. Lindner HA, et al. 2005. Site-directed mutagenesis of the active site region in the quinate/shikimate 5-dehydrogenase YdiB of Escherichia coli. J. Biol. Chem. 280:7162-7169.
24. Lutke-Eversloh T, Santos CN, Stephanopoulos G. 2007. Perspectives of biotechnological production of L-tyrosine and its applications. Appl. Microbiol. Biotechnol. 77:751-762.
25. Lutke-Eversloh T, Stephanopoulos G. 2008. Combinatorial pathway analysis for improved L-tyrosine production in Escherichia coli: identification of enzymatic bottlenecks by systematic gene overexpression. Metab. Eng. 10:69-77.
26. Lutke-Eversloh T, Stephanopoulos G. 2007. L-Tyrosine production by deregulated strains of Escherichia coli. Appl. Microbiol. Biotechnol. 75: 103-110.
27. Lutz R, Bujard H. 1997. Independent and tight regulation of transcriptional units in Escherichia coli via the LacR/O, the TetR/O and AraC/I1-I2 regulatory elements. Nucleic Acids Res. 25:1203-1210.
28. Michel G, et al. 2003. Structures of shikimate dehydrogenase AroE and its paralog YdiB. A common structural framework for different activities. J. Biol. Chem. 278:19463-19472.
29. Minami H, et al. 2008. Microbial production of plant benzylisoquinoline alkaloids. Proc. Natl. Acad. Sci. U. S. A. 105:7393-7398.
30. Muir RM, et al. 2011. Mechanism of gallic acid biosynthesis in bacteria (Escherichia coli) and walnut (Juglans regia). Plant Mol. Biol. 75:555-565.
31. Neidhardt FC, Bloch PL, Smith DF. 1974. Culture medium for enterobacteria. J. Bacteriol. 119:736-747.
32. Oldiges M, Kunze M, Degenring D, Sprenger GA, Takors R. 2004. Stimulation, monitoring, and analysis of pathway dynamics by metabolic profiling in the aromatic amino acid pathway. Biotechnol. Prog. 20: 1623-1633.
33. Olson MM, et al. 2007. Production of L-tyrosine from sucrose or glucose achieved by rapid genetic changes to phenylalanine-producing Escherichia coli strains. Appl. Microbiol. Biotechnol. 74:1031-1040.
34. Patnaik R, Liao JC. 1994. Engineering of Escherichia coli central metabolism for aromatic metabolite production with near theoretical yield. Appl. Environ. Microbiol. 60:3903-3908.
35. Patnaik R, Zolandz RR, Green DA, Kraynie DF. 2008. L-Tyrosine production by recombinant Escherichia coli: fermentation optimization and recovery. Biotechnol. Bioeng. 99:741-752.
36. Redding-Johanson AM, et al. 2011. Targeted proteomics for metabolic pathway optimization: application to terpene production. Metab. Eng. 13:194-203.
37. Rood JI, Sneddon MK, Morrison JF. 1980. Instability in tyrR strains of plasmids carrying the tyrosine operon: isolation and characterization of plasmid derivatives with insertions or deletions. J. Bacteriol. 144:552-559.
38. Santos CN, Stephanopoulos G. 2008. Melanin-based high-throughput screen for L-tyrosine production in Escherichia coli. Appl. Environ. Microbiol. 74:1190-1197.
39. Sariaslani FS. 2007. Development of a combined biological and chemical process for production of industrial aromatics from renewable resources. Annu. Rev. Microbiol. 61:51-69.
40. Sato F, Inui T, Takemura T. 2007. Metabolic engineering in isoquinoline alkaloid biosynthesis. Curr. Pharm. Biotechnol. 8:211-218.
41. Shine J, Dalgarno L. 1974. The 3'-terminal sequence of Escherichia coli 16S ribosomal RNA: complementarity to nonsense triplets and ribosome binding sites. Proc. Natl. Acad. Sci. U. S. A. 71:1342-1346.
42. Sprenger GA. 2007. From scratch to value: engineering Escherichia coli wild type cells to the production of L-phenylalanine and other fine chemicals derived from chorismate. Appl. Microbiol. Biotechnol. 75:739-749.
43. Varma A, Boesch BW, Palsson BØ. 1993. Biochemical production capabilities of Escherichia coli. Biotechnol. Bioeng 42:59-73.
44. Wang H, O'Mahony DJ, McConnell DJ, Qi SZ. 1993. Optimization of the synthesis of porcine somatotropin in Escherichia coli. Appl. Microbiol. Biotechnol. 39:324-328.
45. Weiner MP, Costa GL. 1994. Rapid PCR site-directed mutagenesis. PCR Methods Appl. 4:S131-S136.
46. Whipp MJ, Pittard AJ. 1995. A reassessment of the relationship between aroK- and aroL-encoded shikimate kinase enzymes of Escherichia coli. J. Bacteriol. 177:1627-1629.
47. Yi J, Draths KM, Li K, Frost JW. 2003. Altered glucose transport and shikimate pathway product yields in E. coli. Biotechnol. Prog. 19: 1450-1459.
48. Yi J, Li K, Draths KM, Frost JW. 2002. Modulation of phosphoenolpyruvate synthase expression increases shikimate pathway product yields in E. coli. Biotechnol. Prog. 18:1141-1148.