메뉴 건너뛰기




Volumn 14, Issue 5, 2014, Pages 616-629

Autophagy and heart disease: Implications for cardiac ischemia-reperfusion damage

Author keywords

Autophagy; Heart; Heart disease; Ischemia reperfusion; Mitophagy

Indexed keywords

BECLIN 1; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MICRORNA; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; PARKIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3, 4, 5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN P62; PROTEIN P63; RAB PROTEIN; THYMOCYTE ANTIBODY; TUBERIN; UNCLASSIFIED DRUG;

EID: 84904046211     PISSN: 15665240     EISSN: 18755666     Source Type: Journal    
DOI: 10.2174/1566524014666140603101520     Document Type: Review
Times cited : (48)

References (120)
  • 1
    • 34548477075 scopus 로고    scopus 로고
    • Clinical characteristics and outcome of hospitalized patients with heart failure in Japan
    • Tsutsui H, Tsuchihashi-Makaya M, Kinugawa S, Goto D, Takeshita A. Clinical characteristics and outcome of hospitalized patients with heart failure in Japan. Circulation J 2006; 70(12): 1617-23.
    • (2006) Circulation J , vol.70 , Issue.12 , pp. 1617-1623
    • Tsutsui, H.1    Tsuchihashi-Makaya, M.2    Kinugawa, S.3    Goto, D.4    Takeshita, A.5
  • 2
    • 84885317188 scopus 로고    scopus 로고
    • Autophagy: An affair of the heart
    • Gottlieb RA, Mentzer RM, Jr. Autophagy: an affair of the heart. Heart Fail Rev 2013; 18(5): 575-84.
    • (2013) Heart Fail Rev , vol.18 , Issue.5 , pp. 575-584
    • Gottlieb, R.A.1    Mentzer Jr., R.M.2
  • 3
    • 79952794188 scopus 로고    scopus 로고
    • Lifetime costs of medical care after heart failure diagnosis
    • Dunlay SM, Shah ND, Shi Q, et al. Lifetime costs of medical care after heart failure diagnosis. Circ Cardiovasc Qual Outcomes 2011; 4(1): 68-75.
    • (2011) Circ Cardiovasc Qual Outcomes , vol.4 , Issue.1 , pp. 68-75
    • Dunlay, S.M.1    Shah, N.D.2    Shi, Q.3
  • 4
    • 79959967420 scopus 로고    scopus 로고
    • The role of autophagy emerging in postinfarction cardiac remodelling
    • Kanamori H, Takemura G, Goto K, et al. The role of autophagy emerging in postinfarction cardiac remodelling. Cardiovasc Res 2011; 91(2): 330-9.
    • (2011) Cardiovasc Res , vol.91 , Issue.2 , pp. 330-339
    • Kanamori, H.1    Takemura, G.2    Goto, K.3
  • 8
    • 3442901943 scopus 로고    scopus 로고
    • Autophagy as a bulk protein degradation system: It plays various roles
    • Yoshimori T. [Autophagy as a bulk protein degradation system: it plays various roles]. Tanpakushitsu Kakusan Koso 2004; 49(7 Suppl): 1029-32.
    • (2004) Tanpakushitsu Kakusan Koso , vol.49 , Issue.7 SUPPL. , pp. 1029-1032
    • Yoshimori, T.1
  • 9
    • 84862295360 scopus 로고    scopus 로고
    • Guidelines for the use and interpretation of assays for monitoring autophagy
    • Klionsky DJ, Abdalla FC, Abeliovich H, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 2012; 8(4): 445-544.
    • (2012) Autophagy , vol.8 , Issue.4 , pp. 445-544
    • Klionsky, D.J.1    Abdalla, F.C.2    Abeliovich, H.3
  • 10
    • 77949270765 scopus 로고    scopus 로고
    • S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3
    • Ghavami S, Eshragi M, Ande SR, et al. S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3. Cell Res 2010; 20(3): 314-31.
    • (2010) Cell Res , vol.20 , Issue.3 , pp. 314-331
    • Ghavami, S.1    Eshragi, M.2    Ande, S.R.3
  • 11
    • 79551622901 scopus 로고    scopus 로고
    • Mevalonate cascade regulation of airway mesenchymal cell autophagy and apoptosis: A dual role for p53
    • Ghavami S, Mutawe MM, Sharma P, et al. Mevalonate cascade regulation of airway mesenchymal cell autophagy and apoptosis: a dual role for p53. PLoS One 2011; 6(1): e16523.
    • (2011) PLoS One , vol.6 , Issue.1
    • Ghavami, S.1    Mutawe, M.M.2    Sharma, P.3
  • 12
    • 59849110194 scopus 로고    scopus 로고
    • Autophagy in ischemic heart disease
    • Gustafsson AB, Gottlieb RA. Autophagy in ischemic heart disease. Circ Res 2009; 104(2): 150-8.
    • (2009) Circ Res , vol.104 , Issue.2 , pp. 150-158
    • Gustafsson, A.B.1    Gottlieb, R.A.2
  • 13
    • 84869499324 scopus 로고    scopus 로고
    • Targets, trafficking, and timing of cardiac autophagy
    • Rotter D, Rothermel BA. Targets, trafficking, and timing of cardiac autophagy. Pharmacol Res 2012; 66(6): 494-504.
    • (2012) Pharmacol Res , vol.66 , Issue.6 , pp. 494-504
    • Rotter, D.1    Rothermel, B.A.2
  • 14
    • 84867630057 scopus 로고    scopus 로고
    • Autophagy regulates trans fatty acid-mediated apoptosis in primary cardiac myofibroblasts
    • Ghavami S, Cunnington RH, Yeganeh B, et al. Autophagy regulates trans fatty acid-mediated apoptosis in primary cardiac myofibroblasts. Biochim Biophys Acta 2012; 1823(12): 2274-86.
    • (2012) Biochim Biophys Acta , vol.1823 , Issue.12 , pp. 2274-2286
    • Ghavami, S.1    Cunnington, R.H.2    Yeganeh, B.3
  • 15
    • 84875508562 scopus 로고    scopus 로고
    • Asthma and influenza virus infection:Focusing on cell death and stress pathways in influenza virus replication
    • Yeganeh B, Rezaei Moghadam A, Tran AT, et al. Asthma and influenza virus infection:focusing on cell death and stress pathways in influenza virus replication. Iran J Allergy Asthma Immunol 2013; 12(1): 1-17.
    • (2013) Iran J Allergy Asthma Immunol , vol.12 , Issue.1 , pp. 1-17
    • Yeganeh, B.1    Rezaei, M.A.2    Tran, A.T.3
  • 16
    • 84877584521 scopus 로고    scopus 로고
    • Beclin 1 and autophagy are required for the tumorigenicity of breast cancer stemlike/ progenitor cells
    • Gong C, Bauvy C, Tonelli G, et al. Beclin 1 and autophagy are required for the tumorigenicity of breast cancer stemlike/ progenitor cells. Oncogene 2013; 32(18): 2261-72, 2272e.1-11.
    • (2013) Oncogene , vol.32 , Issue.18 , pp. 2261-2272
    • Gong, C.1    Bauvy, C.2    Tonelli, G.3
  • 17
    • 67649467294 scopus 로고    scopus 로고
    • Dynamics and diversity in autophagy mechanisms: Lessons from yeast
    • Nakatogawa H, Suzuki K, Kamada Y, Ohsumi Y. Dynamics and diversity in autophagy mechanisms: lessons from yeast. Nat Rev Mol Cell Biol 2009; 10(7): 458-67.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , Issue.7 , pp. 458-467
    • Nakatogawa, H.1    Suzuki, K.2    Kamada, Y.3    Ohsumi, Y.4
  • 18
    • 84863425318 scopus 로고    scopus 로고
    • Apoptosis, autophagy and ER stress in mevalonate cascade inhibitioninduced cell death of human atrial fibroblasts
    • Ghavami S, Yeganeh B, Stelmack GL, et al. Apoptosis, autophagy and ER stress in mevalonate cascade inhibitioninduced cell death of human atrial fibroblasts. Cell Death Dis 2012; 3: e330.
    • (2012) Cell Death Dis , vol.3
    • Ghavami, S.1    Yeganeh, B.2    Stelmack, G.L.3
  • 19
    • 79952628267 scopus 로고    scopus 로고
    • The Beclin 1 network regulates autophagy and apoptosis
    • Kang R, Zeh HJ, Lotze MT, Tang D. The Beclin 1 network regulates autophagy and apoptosis. Cell Death Differ 2011; 18(4): 571-80.
    • (2011) Cell Death Differ , vol.18 , Issue.4 , pp. 571-580
    • Kang, R.1    Zeh, H.J.2    Lotze, M.T.3    Tang, D.4
  • 20
    • 77951217000 scopus 로고    scopus 로고
    • Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase
    • Wu YT, Tan HL, Shui G, et al. Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase. J Biol Chem 2010; 285(14): 10850-61.
    • (2010) J Biol Chem , vol.285 , Issue.14 , pp. 10850-10861
    • Wu, Y.T.1    Tan, H.L.2    Shui, G.3
  • 21
    • 38049098543 scopus 로고    scopus 로고
    • The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy
    • Hanada T, Noda NN, Satomi Y, et al. The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy. J Biol Chem 2007; 282(52): 37298-302.
    • (2007) J Biol Chem , vol.282 , Issue.52 , pp. 37298-37302
    • Hanada, T.1    Noda, N.N.2    Satomi, Y.3
  • 23
    • 84882686716 scopus 로고    scopus 로고
    • Salinomycin induces activation of autophagy, mitophagy and affects mitochondrial polarity: Differences between primary and cancer cells
    • Jangamreddy JR, Ghavami S, Grabarek J, et al. Salinomycin induces activation of autophagy, mitophagy and affects mitochondrial polarity: differences between primary and cancer cells. Biochim Biophys Acta 2013; 1833(9): 2057-69.
    • (2013) Biochim Biophys Acta , vol.1833 , Issue.9 , pp. 2057-2069
    • Jangamreddy, J.R.1    Ghavami, S.2    Grabarek, J.3
  • 24
    • 78149475088 scopus 로고    scopus 로고
    • Regulation of mammalian autophagy in physiology and pathophysiology
    • Ravikumar B, Sarkar S, Davies JE, et al. Regulation of mammalian autophagy in physiology and pathophysiology. Physiol Rev 2010; 90(4): 1383-435.
    • (2010) Physiol Rev , vol.90 , Issue.4 , pp. 1383-1435
    • Ravikumar, B.1    Sarkar, S.2    Davies, J.E.3
  • 25
    • 84871037851 scopus 로고    scopus 로고
    • Fibroblast autophagy in fibrotic disorders
    • Del Principe D, Lista P, Malorni W, Giammarioli AM. Fibroblast autophagy in fibrotic disorders. J Pathol 2013; 229(2): 208-20.
    • (2013) J Pathol , vol.229 , Issue.2 , pp. 208-220
    • Del, P.D.1    Lista, P.2    Malorni, W.3    Giammarioli, A.M.4
  • 26
    • 84862908818 scopus 로고    scopus 로고
    • AMPK and mTOR in cellular energy homeostasis and drug targets
    • Inoki K, Kim J, Guan KL. AMPK and mTOR in cellular energy homeostasis and drug targets. Annu Rev Pharmacol Toxicol 2012; 52: 381-400.
    • (2012) Annu Rev Pharmacol Toxicol , vol.52 , pp. 381-400
    • Inoki, K.1    Kim, J.2    Guan, K.L.3
  • 28
    • 77951227871 scopus 로고    scopus 로고
    • TOR-dependent control of autophagy: Biting the hand that feeds
    • Neufeld TP. TOR-dependent control of autophagy: biting the hand that feeds. Curr Opin Cell Biol 2010; 22(2): 157-68.
    • (2010) Curr Opin Cell Biol , vol.22 , Issue.2 , pp. 157-168
    • Neufeld, T.P.1
  • 29
    • 44449161481 scopus 로고    scopus 로고
    • The TSC1-TSC2 complex: A molecular switchboard controlling cell growth
    • Huang J, Manning BD. The TSC1-TSC2 complex: a molecular switchboard controlling cell growth. Biochem J 2008; 412(2): 179-90.
    • (2008) Biochem J , vol.412 , Issue.2 , pp. 179-190
    • Huang, J.1    Manning, B.D.2
  • 30
    • 62349138654 scopus 로고    scopus 로고
    • Characterization of the intrinsic and TSC2-GAP-regulated GTPase activity of Rheb by real-time NMR
    • Marshall CB, Ho J, Buerger C, et al. Characterization of the intrinsic and TSC2-GAP-regulated GTPase activity of Rheb by real-time NMR. Sci Signal 2009; 2(55): ra3.
    • (2009) Sci Signal , vol.2 , Issue.55
    • Marshall, C.B.1    Ho, J.2    Buerger, C.3
  • 31
    • 79953736356 scopus 로고    scopus 로고
    • Is autophagy in response to ischemia and reperfusion protective or detrimental for the heart?
    • Sciarretta S, Hariharan N, Monden Y, Zablocki D, Sadoshima J. Is autophagy in response to ischemia and reperfusion protective or detrimental for the heart? Pediatr Cardiol 2011; 32(3): 275-81.
    • (2011) Pediatr Cardiol , vol.32 , Issue.3 , pp. 275-281
    • Sciarretta, S.1    Hariharan, N.2    Monden, Y.3    Zablocki, D.4    Sadoshima, J.5
  • 32
    • 84884676252 scopus 로고    scopus 로고
    • Nutrient signaling to mTOR and cell growth
    • Jewell JL, Guan KL. Nutrient signaling to mTOR and cell growth. Trends Biochem Sci 2013; 38(5): 233-42.
    • (2013) Trends Biochem Sci , vol.38 , Issue.5 , pp. 233-242
    • Jewell, J.L.1    Guan, K.L.2
  • 33
  • 34
  • 35
  • 36
    • 84857004809 scopus 로고    scopus 로고
    • Geranylgeranyl transferase 1 modulates autophagy and apoptosis in human airway smooth muscle
    • Ghavami S, Mutawe MM, Schaafsma D, et al. Geranylgeranyl transferase 1 modulates autophagy and apoptosis in human airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 2012; 302(4): L420-8.
    • (2012) Am J Physiol Lung Cell Mol Physiol , vol.302 , Issue.4
    • Ghavami, S.1    Mutawe, M.M.2    Schaafsma, D.3
  • 37
    • 79960323911 scopus 로고    scopus 로고
    • AMPK-> ULK1-> autophagy
    • Roach PJ. AMPK-> ULK1-> autophagy. Mol Cell Biol 2011; 31(15): 3082-4.
    • (2011) Mol Cell Biol , vol.31 , Issue.15 , pp. 3082-3084
    • Roach, P.J.1
  • 38
    • 84877995295 scopus 로고    scopus 로고
    • Evolution of Tre-2/Bub2/Cdc16 (TBC) Rab GTPaseactivating proteins
    • Gabernet-Castello C, O'Reilly AJ, Dacks JB, Field MC. Evolution of Tre-2/Bub2/Cdc16 (TBC) Rab GTPaseactivating proteins. Mol Biol Cell 2013; 24(10): 1574-83.
    • (2013) Mol Biol Cell , vol.24 , Issue.10 , pp. 1574-1583
    • Gabernet-Castello, C.1    O'Reilly, A.J.2    Dacks, J.B.3    Field, M.C.4
  • 39
    • 84860296724 scopus 로고    scopus 로고
    • AMP-activated protein kinase, stress responses and cardiovascular diseases
    • Wang S, Song P, Zou MH. AMP-activated protein kinase, stress responses and cardiovascular diseases. Clin Sci (Lond) 2012; 122(12): 555-73.
    • (2012) Clin Sci (Lond) , vol.122 , Issue.12 , pp. 555-573
    • Wang, S.1    Song, P.2    Zou, M.H.3
  • 40
    • 77951221542 scopus 로고    scopus 로고
    • The role of the Atg1/ULK1 complex in autophagy regulation
    • Mizushima N. The role of the Atg1/ULK1 complex in autophagy regulation. Curr Opin Cell Biol 2010; 22(2): 132-9.
    • (2010) Curr Opin Cell Biol , vol.22 , Issue.2 , pp. 132-139
    • Mizushima, N.1
  • 41
    • 84873569898 scopus 로고    scopus 로고
    • Interaction between FIP200 and ATG16L1 distinguishes ULK1 complexdependent and-independent autophagy
    • Gammoh N, Florey O, Overholtzer M, Jiang X. Interaction between FIP200 and ATG16L1 distinguishes ULK1 complexdependent and-independent autophagy. Nat Str Mol Biol 2013; 20(2): 144-9.
    • (2013) Nat Str Mol Biol , vol.20 , Issue.2 , pp. 144-149
    • Gammoh, N.1    Florey, O.2    Overholtzer, M.3    Jiang, X.4
  • 42
    • 57049094929 scopus 로고    scopus 로고
    • Suppression of autophagy in skeletal muscle uncovers the accumulation of ubiquitinated proteins and their potential role in muscle damage in Pompe disease
    • Raben N, Hill V, Shea L, et al. Suppression of autophagy in skeletal muscle uncovers the accumulation of ubiquitinated proteins and their potential role in muscle damage in Pompe disease. Hum Mol Genet 2008; 17(24): 3897-908.
    • (2008) Hum Mol Genet , vol.17 , Issue.24 , pp. 3897-3908
    • Raben, N.1    Hill, V.2    Shea, L.3
  • 43
    • 79958034358 scopus 로고    scopus 로고
    • Enhancing AMPK activation during ischemia protects the diabetic heart against reperfusion injury
    • Paiva MA, Rutter-Locher Z, Goncalves LM, et al. Enhancing AMPK activation during ischemia protects the diabetic heart against reperfusion injury. Am J Physiol Heart Circ Physiol 2011; 300(6): H2123-34.
    • (2011) Am J Physiol Heart Circ Physiol , vol.300 , Issue.6
    • Paiva, M.A.1    Rutter-Locher, Z.2    Goncalves, L.M.3
  • 44
    • 80053393865 scopus 로고    scopus 로고
    • AMP-activated protein kinase modulates cardiac autophagy in diabetic cardiomyopathy
    • Xie Z, He C, Zou MH. AMP-activated protein kinase modulates cardiac autophagy in diabetic cardiomyopathy. Autophagy 2011; 7(10): 1254-5.
    • (2011) Autophagy , vol.7 , Issue.10 , pp. 1254-1255
    • Xie, Z.1    He, C.2    Zou, M.H.3
  • 46
    • 79956118584 scopus 로고    scopus 로고
    • Autophagy signaling through reactive oxygen species
    • Huang J, Lam GY, Brumell JH. Autophagy signaling through reactive oxygen species. Antioxid Redox Signal 2011; 14(11): 2215-31.
    • (2011) Antioxid Redox Signal , vol.14 , Issue.11 , pp. 2215-2231
    • Huang, J.1    Lam, G.Y.2    Brumell, J.H.3
  • 47
    • 66349121718 scopus 로고    scopus 로고
    • Hypoxiainduced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains
    • Bellot G, Garcia-Medina R, Gounon P, et al. Hypoxiainduced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains. Mol Cell Biol 2009; 29(10): 2570-81.
    • (2009) Mol Cell Biol , vol.29 , Issue.10 , pp. 2570-2581
    • Bellot, G.1    Garcia-Medina, R.2    Gounon, P.3
  • 48
    • 79957952535 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1: Regulator of mitochondrial metabolism and mediator of ischemic preconditioning
    • Semenza GL. Hypoxia-inducible factor 1: regulator of mitochondrial metabolism and mediator of ischemic preconditioning. Biochim Biophys Acta 2011; 1813(7): 1263-8.
    • (2011) Biochim Biophys Acta , vol.1813 , Issue.7 , pp. 1263-1268
    • Semenza, G.L.1
  • 49
    • 84886412451 scopus 로고    scopus 로고
    • Hypoxia-Inducible Factor 1 and Cardiovascular Disease
    • Semenza GL. Hypoxia-Inducible Factor 1 and Cardiovascular Disease. Annu Rev Physiol 2014; 76: 39-56.
    • (2014) Annu Rev Physiol , vol.76 , pp. 39-56
    • Semenza, G.L.1
  • 50
    • 84859469406 scopus 로고    scopus 로고
    • Endothelial expression of hypoxia-inducible factor 1 protects the murine heart and aorta from pressure overload by suppression of TGF-beta signaling
    • Wei H, Bedja D, Koitabashi N, et al. Endothelial expression of hypoxia-inducible factor 1 protects the murine heart and aorta from pressure overload by suppression of TGF-beta signaling. Proc Natl Acad Sci U S A 2012; 109(14): E841-50.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , Issue.14
    • Wei, H.1    Bedja, D.2    Koitabashi, N.3
  • 52
    • 84894543856 scopus 로고    scopus 로고
    • In vivo electroporation of constitutively expressed HIF-1alpha plasmid DNA improves neovascularization in a mouse model of limb ischemia
    • Ouma GO, Rodriguez E, Muthumani K, Weiner DB, Wilensky RL, Mohler ER, 3rd. In vivo electroporation of constitutively expressed HIF-1alpha plasmid DNA improves neovascularization in a mouse model of limb ischemia. J Vasc Surg 2014; 59(3): 786-93.
    • (2014) J Vasc Surg , vol.59 , Issue.3 , pp. 786-793
    • Ouma, G.O.1    Rodriguez, E.2    Muthumani, K.3    Weiner, D.B.4    Wilensky, R.L.5    Mohler III, E.R.6
  • 54
    • 66049097308 scopus 로고    scopus 로고
    • Activation of a HIF1alpha-PPARgamma axis underlies the integration of glycolytic and lipid anabolic pathways in pathologic cardiac hypertrophy
    • Krishnan J, Suter M, Windak R, et al. Activation of a HIF1alpha-PPARgamma axis underlies the integration of glycolytic and lipid anabolic pathways in pathologic cardiac hypertrophy. Cell Metab 2009; 9(6): 512-24.
    • (2009) Cell Metab , vol.9 , Issue.6 , pp. 512-524
    • Krishnan, J.1    Suter, M.2    Windak, R.3
  • 55
    • 84867724832 scopus 로고    scopus 로고
    • Mitochondria and mitophagy: The yin and yang of cell death control
    • Kubli DA, Gustafsson AB. Mitochondria and mitophagy: the yin and yang of cell death control. Circ Res 2012; 111(9): 1208-21.
    • (2012) Circ Res , vol.111 , Issue.9 , pp. 1208-1221
    • Kubli, D.A.1    Gustafsson, A.B.2
  • 56
    • 34848920863 scopus 로고    scopus 로고
    • ROS, mitochondria and the regulation of autophagy
    • Scherz-Shouval R, Elazar Z. ROS, mitochondria and the regulation of autophagy. Trends Cell Biol 2007; 17(9): 422-7.
    • (2007) Trends Cell Biol , vol.17 , Issue.9 , pp. 422-427
    • Scherz-Shouval, R.1    Elazar, Z.2
  • 58
    • 84861204926 scopus 로고    scopus 로고
    • PINK1-and Parkin-mediated mitophagy at a glance
    • Jin SM, Youle RJ. PINK1-and Parkin-mediated mitophagy at a glance. J Cell Sci 2012; 125(Pt 4): 795-9.
    • (2012) J Cell Sci , vol.125 , Issue.Pt 4 , pp. 795-799
    • Jin, S.M.1    Youle, R.J.2
  • 59
    • 84859739780 scopus 로고    scopus 로고
    • The physiological role of mitophagy: New insights into phosphorylation events
    • Hirota Y, Kang D, Kanki T. The physiological role of mitophagy: new insights into phosphorylation events. Int J Cell Biol 2012; 2012: 354914.
    • (2012) Int J Cell Biol , vol.2012 , pp. 354914
    • Hirota, Y.1    Kang, D.2    Kanki, T.3
  • 61
    • 84882425828 scopus 로고    scopus 로고
    • Cytosolic p53 inhibits Parkin-mediated mitophagy and promotes mitochondrial dysfunction in the mouse heart
    • Hoshino A, Mita Y, Okawa Y, et al. Cytosolic p53 inhibits Parkin-mediated mitophagy and promotes mitochondrial dysfunction in the mouse heart. Nat Commun 2013; 4: 2308.
    • Nat Commun , vol.2013 , pp. 4
    • Hoshino, A.1    Mita, Y.2    Okawa, Y.3
  • 62
    • 84885084776 scopus 로고    scopus 로고
    • Creatine Kinase-Overexpression Improves Myocardial Energetics, Contractile Dysfunction and Survival in Murine Doxorubicin Cardiotoxicity
    • Gupta A, Rohlfsen C, Leppo MK, et al. Creatine Kinase-Overexpression Improves Myocardial Energetics, Contractile Dysfunction and Survival in Murine Doxorubicin Cardiotoxicity. PLoS One 2013; 8(10): e74675.
    • (2013) PLoS One , vol.8 , Issue.10
    • Gupta, A.1    Rohlfsen, C.2    Leppo, M.K.3
  • 63
    • 84901733241 scopus 로고    scopus 로고
    • Senescent cardiac fibroblast is critical for cardiac fibrosis after myocardial infarction
    • Zhu F, Li Y, Zhang J, et al. Senescent cardiac fibroblast is critical for cardiac fibrosis after myocardial infarction. PLoS One 2013; 8(9): e74535.
    • (2013) PLoS One , vol.8 , Issue.9
    • Zhu, F.1    Li, Y.2    Zhang, J.3
  • 65
    • 84862891256 scopus 로고    scopus 로고
    • Ischemia-reperfusion induces myocardial infarction through mitochondrial Ca(2)(+) overload
    • Shintani-Ishida K, Inui M, Yoshida K. Ischemia-reperfusion induces myocardial infarction through mitochondrial Ca(2)(+) overload. J Mol Cell Cardiol 2012; 53(2): 233-9.
    • (2012) J Mol Cell Cardiol , vol.53 , Issue.2 , pp. 233-239
    • Shintani-Ishida, K.1    Inui, M.2    Yoshida, K.3
  • 66
    • 0034110883 scopus 로고    scopus 로고
    • L-Arginine administration prevents reperfusion-induced cardiomyocyte hypercontracture and reduces infarct size in the pig
    • Padilla F, Garcia-Dorado D, Agullo L, et al. L-Arginine administration prevents reperfusion-induced cardiomyocyte hypercontracture and reduces infarct size in the pig. Cardiovasc Res 2000; 46(3): 412-20.
    • (2000) Cardiovasc Res , vol.46 , Issue.3 , pp. 412-420
    • Padilla, F.1    Garcia-Dorado, D.2    Agullo, L.3
  • 67
    • 79955963895 scopus 로고    scopus 로고
    • At the core of survival: Autophagy delays the onset of both apoptotic and necrotic cell death in a model of ischemic cell injury
    • Loos B, Genade S, Ellis B, Lochner A, Engelbrecht AM. At the core of survival: autophagy delays the onset of both apoptotic and necrotic cell death in a model of ischemic cell injury. Exp Cell Res 2011; 317(10): 1437-53.
    • (2011) Exp Cell Res , vol.317 , Issue.10 , pp. 1437-1453
    • Loos, B.1    Genade, S.2    Ellis, B.3    Lochner, A.4    Engelbrecht, A.M.5
  • 68
    • 34147168105 scopus 로고    scopus 로고
    • Distinct roles of autophagy in the heart during ischemia and reperfusion: Roles of AMPactivated protein kinase and Beclin 1 in mediating autophagy
    • Matsui Y, Takagi H, Qu X, et al. Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMPactivated protein kinase and Beclin 1 in mediating autophagy. Circ Res 2007; 100(6): 914-22.
    • (2007) Circ Res , vol.100 , Issue.6 , pp. 914-922
    • Matsui, Y.1    Takagi, H.2    Qu, X.3
  • 69
    • 25444473426 scopus 로고    scopus 로고
    • Autophagy in chronically ischemic myocardium
    • Yan L, Vatner DE, Kim SJ, et al. Autophagy in chronically ischemic myocardium. Proc Natl Acad Sci U S A 2005; 102(39): 13807-12.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , Issue.39 , pp. 13807-13812
    • Yan, L.1    Vatner, D.E.2    Kim, S.J.3
  • 70
    • 78149469146 scopus 로고    scopus 로고
    • Autophagy in myocardium of murine hearts subjected to ischemia followed by reperfusion
    • French CJ, Taatjes DJ, Sobel BE. Autophagy in myocardium of murine hearts subjected to ischemia followed by reperfusion. Histochem Cell Biol 2010; 134(5): 519-26.
    • (2010) Histochem Cell Biol , vol.134 , Issue.5 , pp. 519-526
    • French, C.J.1    Taatjes, D.J.2    Sobel, B.E.3
  • 71
    • 84866316328 scopus 로고    scopus 로고
    • Cardiac autophagy: Good with the bad
    • Rifki OF, Hill JA. Cardiac autophagy: good with the bad. J Cardiovasc Pharmacol 2012; 60(3): 248-52.
    • (2012) J Cardiovasc Pharmacol , vol.60 , Issue.3 , pp. 248-252
    • Rifki, O.F.1    Hill, J.A.2
  • 73
    • 0018827202 scopus 로고
    • Lysosomal alterations in hypoxic and reoxygenated hearts. I. Ultrastructural and cytochemical changes
    • Decker RS, Wildenthal K. Lysosomal alterations in hypoxic and reoxygenated hearts. I. Ultrastructural and cytochemical changes. Am J Pathol 1980; 98(2): 425-44.
    • (1980) Am J Pathol , vol.98 , Issue.2 , pp. 425-444
    • Decker, R.S.1    Wildenthal, K.2
  • 75
    • 0019142775 scopus 로고
    • Lysosomal vacuolar apparatus of cardiac myocytes in heart of starved and refed rabbits
    • Decker RS, Decker ML, Herring GH, Morton PC, Wildenthal K. Lysosomal vacuolar apparatus of cardiac myocytes in heart of starved and refed rabbits. J Mol Cell Cardiol 1980; 12(11): 1175-89.
    • (1980) J Mol Cell Cardiol , vol.12 , Issue.11 , pp. 1175-1189
    • Decker, R.S.1    Decker, M.L.2    Herring, G.H.3    Morton, P.C.4    Wildenthal, K.5
  • 76
    • 84863192578 scopus 로고    scopus 로고
    • Impaired autophagosome clearance contributes to cardiomyocyte death in ischemia/reperfusion injury
    • Ma X, Liu H, Foyil SR, et al. Impaired autophagosome clearance contributes to cardiomyocyte death in ischemia/reperfusion injury. Circulation 2012; 125(25): 3170-81.
    • (2012) Circulation , vol.125 , Issue.25 , pp. 3170-3181
    • Ma, X.1    Liu, H.2    Foyil, S.R.3
  • 77
    • 0036735949 scopus 로고    scopus 로고
    • Role of LAMP-2 in lysosome biogenesis and autophagy
    • Eskelinen EL, Illert AL, Tanaka Y, et al. Role of LAMP-2 in lysosome biogenesis and autophagy. Mol Biol Cell 2002; 13(9): 3355-68.
    • (2002) Mol Biol Cell , vol.13 , Issue.9 , pp. 3355-3368
    • Eskelinen, E.L.1    Illert, A.L.2    Tanaka, Y.3
  • 78
    • 84880284860 scopus 로고    scopus 로고
    • Protein oxidation seems to be linked to constitutive autophagy: A sex study
    • Campesi I, Straface E, Occhioni S, Montella A, Franconi F. Protein oxidation seems to be linked to constitutive autophagy: a sex study. Life Sci 2013; 93(4): 145-52.
    • (2013) Life Sci , vol.93 , Issue.4 , pp. 145-152
    • Campesi, I.1    Straface, E.2    Occhioni, S.3    Montella, A.4    Franconi, F.5
  • 80
    • 84555195856 scopus 로고    scopus 로고
    • Autophagy, mitochondria and oxidative stress: Cross-talk and redox signalling
    • Lee J, Giordano S, Zhang J. Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling. Biochem J 2012; 441(2): 523-40.
    • (2012) Biochem J , vol.441 , Issue.2 , pp. 523-540
    • Lee, J.1    Giordano, S.2    Zhang, J.3
  • 81
    • 79952217013 scopus 로고    scopus 로고
    • Cancer causes cardiac atrophy and autophagy in a sexually dimorphic manner
    • Cosper PF, Leinwand LA. Cancer causes cardiac atrophy and autophagy in a sexually dimorphic manner. Cancer Res 2011; 71(5): 1710-20.
    • (2011) Cancer Res , vol.71 , Issue.5 , pp. 1710-1720
    • Cosper, P.F.1    Leinwand, L.A.2
  • 82
    • 84881318188 scopus 로고    scopus 로고
    • Apoptosis and autophagy contribute to gender difference in cardiac ischemiareperfusion induced injury in rats
    • Chen C, Hu LX, Dong T, et al. Apoptosis and autophagy contribute to gender difference in cardiac ischemiareperfusion induced injury in rats. Life Sci 2013; 93(7): 265-70.
    • (2013) Life Sci , vol.93 , Issue.7 , pp. 265-270
    • Chen, C.1    Hu, L.X.2    Dong, T.3
  • 83
    • 20444398494 scopus 로고    scopus 로고
    • Molecular and cellular basis of cardiovascular gender differences
    • Mendelsohn ME, Karas RH. Molecular and cellular basis of cardiovascular gender differences. Science 2005; 308(5728): 1583-7.
    • (2005) Science , vol.308 , Issue.5728 , pp. 1583-1587
    • Mendelsohn, M.E.1    Karas, R.H.2
  • 84
    • 84867691699 scopus 로고    scopus 로고
    • Mitochondrial control of cellular life, stress, and death
    • Galluzzi L, Kepp O, Trojel-Hansen C, Kroemer G. Mitochondrial control of cellular life, stress, and death. Circ Res 2012; 111(9): 1198-207.
    • (2012) Circ Res , vol.111 , Issue.9 , pp. 1198-1207
    • Galluzzi, L.1    Kepp, O.2    Trojel-Hansen, C.3    Kroemer, G.4
  • 85
    • 38149044992 scopus 로고    scopus 로고
    • Induction of autophagy promotes fusion of multivesicular bodies with autophagic vacuoles in k562 cells
    • Fader CM, Sanchez D, Furlan M, Colombo MI. Induction of autophagy promotes fusion of multivesicular bodies with autophagic vacuoles in k562 cells. Traffic 2008; 9(2): 230-50.
    • (2008) Traffic , vol.9 , Issue.2 , pp. 230-250
    • Fader, C.M.1    Sanchez, D.2    Furlan, M.3    Colombo, M.I.4
  • 86
    • 84862611041 scopus 로고    scopus 로고
    • TBC1D14 regulates autophagosome formation via Rab11-and ULK1-positive recycling endosomes
    • Longatti A, Lamb CA, Razi M, Yoshimura S, Barr FA, Tooze SA. TBC1D14 regulates autophagosome formation via Rab11-and ULK1-positive recycling endosomes. J Cell Biol 2012; 197(5): 659-75.
    • (2012) J Cell Biol , vol.197 , Issue.5 , pp. 659-675
    • Longatti, A.1    Lamb, C.A.2    Razi, M.3    Yoshimura, S.4    Barr, F.A.5    Tooze, S.A.6
  • 87
    • 84877582117 scopus 로고    scopus 로고
    • Rab12 regulates mTORC1 activity and autophagy through controlling the degradation of amino-acid transporter PAT4
    • Matsui T, Fukuda M. Rab12 regulates mTORC1 activity and autophagy through controlling the degradation of amino-acid transporter PAT4. EMBO Rep 2013; 14(5): 450-7.
    • (2013) EMBO Rep , vol.14 , Issue.5 , pp. 450-457
    • Matsui, T.1    Fukuda, M.2
  • 88
    • 77954757143 scopus 로고    scopus 로고
    • Protonassisted amino-acid transporters are conserved regulators of proliferation and amino-acid-dependent mTORC1 activation
    • Heublein S, Kazi S, Ogmundsdottir MH, et al. Protonassisted amino-acid transporters are conserved regulators of proliferation and amino-acid-dependent mTORC1 activation. Oncogene 2010; 29(28): 4068-79.
    • (2010) Oncogene , vol.29 , Issue.28 , pp. 4068-4079
    • Heublein, S.1    Kazi, S.2    Ogmundsdottir, M.H.3
  • 89
    • 80555143078 scopus 로고    scopus 로고
    • mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase
    • Zoncu R, Bar-Peled L, Efeyan A, Wang S, Sancak Y, Sabatini DM. mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase. Science 2011; 334(6056): 678-83.
    • (2011) Science , vol.334 , Issue.6056 , pp. 678-683
    • Zoncu, R.1    Bar-Peled, L.2    Efeyan, A.3    Wang, S.4    Sancak, Y.5    Sabatini, D.M.6
  • 90
    • 0030457014 scopus 로고    scopus 로고
    • Ubiquitin-dependent protein degradation
    • Hochstrasser M. Ubiquitin-dependent protein degradation. Annu Rev Genet 1996; 30: 405-39.
    • (1996) Annu Rev Genet , vol.30 , pp. 405-439
    • Hochstrasser, M.1
  • 91
    • 33748528911 scopus 로고    scopus 로고
    • Into the heart: The emerging role of the ubiquitin-proteasome system
    • Willis MS, Patterson C. Into the heart: the emerging role of the ubiquitin-proteasome system. J Mol Cell Cardiol 2006; 41(4): 567-79.
    • (2006) J Mol Cell Cardiol , vol.41 , Issue.4 , pp. 567-579
    • Willis, M.S.1    Patterson, C.2
  • 92
    • 0035947372 scopus 로고    scopus 로고
    • Impairment of the ubiquitin-proteasome system by protein aggregation
    • Bence NF, Sampat RM, Kopito RR. Impairment of the ubiquitin-proteasome system by protein aggregation. Science 2001; 292(5521): 1552-5.
    • (2001) Science , vol.292 , Issue.5521 , pp. 1552-1555
    • Bence, N.F.1    Sampat, R.M.2    Kopito, R.R.3
  • 93
    • 47749105267 scopus 로고    scopus 로고
    • Intracellular protein aggregation is a proximal trigger of cardiomyocyte autophagy
    • Tannous P, Zhu H, Nemchenko A, et al. Intracellular protein aggregation is a proximal trigger of cardiomyocyte autophagy. Circulation 2008; 117(24): 3070-8.
    • (2008) Circulation , vol.117 , Issue.24 , pp. 3070-3078
    • Tannous, P.1    Zhu, H.2    Nemchenko, A.3
  • 94
    • 84872725111 scopus 로고    scopus 로고
    • Mitochondrial aldehyde dehydrogenase 2 activation and cardioprotection
    • Gong D, Zhang H, Hu S. Mitochondrial aldehyde dehydrogenase 2 activation and cardioprotection. J Mol Cell Cardiol 2013; 55: 58-63.
    • (2013) J Mol Cell Cardiol , vol.55 , pp. 58-63
    • Gong, D.1    Zhang, H.2    Hu, S.3
  • 95
    • 84887987876 scopus 로고    scopus 로고
    • Roles of microRNAs in pressure overload-and ischemia-related myocardial remodeling
    • Zhou S, Liu Y, Prater K, Zheng Y, Cai L. Roles of microRNAs in pressure overload-and ischemia-related myocardial remodeling. Life Sci 2013; 93(23): 855-62.
    • (2013) Life Sci , vol.93 , Issue.23 , pp. 855-862
    • Zhou, S.1    Liu, Y.2    Prater, K.3    Zheng, Y.4    Cai, L.5
  • 96
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004; 116(2): 281-97.
    • (2004) Cell , vol.116 , Issue.2 , pp. 281-297
    • Bartel, D.P.1
  • 98
    • 84885502197 scopus 로고    scopus 로고
    • MicroRNA transcriptome profiling in cardiac tissue of hypertrophic cardiomyopathy patients with MYBPC3 mutations
    • Kuster DW, Mulders J, Ten Cate FJ, et al. MicroRNA transcriptome profiling in cardiac tissue of hypertrophic cardiomyopathy patients with MYBPC3 mutations. J Mol Cell Cardiol 2013; 65: 59-66.
    • (2013) J Mol Cell Cardiol , vol.65 , pp. 59-66
    • Kuster, D.W.1    Mulders, J.2    Ten, C.F.J.3
  • 99
    • 34447318648 scopus 로고    scopus 로고
    • MicroRNAs are aberrantly expressed in hypertrophic heart: Do they play a role in cardiac hypertrophy?
    • Cheng Y, Ji R, Yue J, et al. MicroRNAs are aberrantly expressed in hypertrophic heart: do they play a role in cardiac hypertrophy? Am J Pathol 2007; 170(6): 1831-40.
    • (2007) Am J Pathol , vol.170 , Issue.6 , pp. 1831-1840
    • Cheng, Y.1    Ji, R.2    Yue, J.3
  • 100
    • 57749168828 scopus 로고    scopus 로고
    • MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts
    • Thum T, Gross C, Fiedler J, et al. MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature 2008; 456(7224): 980-4.
    • (2008) Nature , vol.456 , Issue.7224 , pp. 980-984
    • Thum, T.1    Gross, C.2    Fiedler, J.3
  • 101
    • 84879604162 scopus 로고    scopus 로고
    • NF-kappaB-mediated induction of autophagy in cardiac ischemia/reperfusion injury
    • Zeng M, Wei X, Wu Z, et al. NF-kappaB-mediated induction of autophagy in cardiac ischemia/reperfusion injury. Biochem Biophys Res Commun 2013; 436(2): 180-5.
    • (2013) Biochem Biophys Res Commun , vol.436 , Issue.2 , pp. 180-185
    • Zeng, M.1    Wei, X.2    Wu, Z.3
  • 102
    • 33846214438 scopus 로고    scopus 로고
    • Inhibition of NF-{kappa}B improves left ventricular remodeling and cardiac dysfunction after myocardial infarction
    • Onai Y, Suzuki J, Maejima Y, et al. Inhibition of NF-{kappa}B improves left ventricular remodeling and cardiac dysfunction after myocardial infarction. Am J Physiol Heart Circ Physiol 2007; 292(1): H530-8.
    • (2007) Am J Physiol Heart Circ Physiol , vol.292 , Issue.1
    • Onai, Y.1    Suzuki, J.2    Maejima, Y.3
  • 103
    • 0028985037 scopus 로고
    • NF-kappa B and rel proteins in innate immunity
    • Kopp EB, Ghosh S. NF-kappa B and rel proteins in innate immunity. Adv Immunol 1995; 58: 1-27.
    • (1995) Adv Immunol , vol.58 , pp. 1-27
    • Kopp, E.B.1    Ghosh, S.2
  • 104
    • 56249135538 scopus 로고    scopus 로고
    • A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
    • Cadwell K, Liu JY, Brown SL, et al. A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells. Nature 2008; 456(7219): 259-63.
    • (2008) Nature , vol.456 , Issue.7219 , pp. 259-263
    • Cadwell, K.1    Liu, J.Y.2    Brown, S.L.3
  • 105
    • 61649114427 scopus 로고    scopus 로고
    • A common role for Atg16L1, Atg5 and Atg7 in small intestinal Paneth cells and Crohn disease
    • Cadwell K, Patel KK, Komatsu M, Virgin HWt, Stappenbeck TS. A common role for Atg16L1, Atg5 and Atg7 in small intestinal Paneth cells and Crohn disease. Autophagy 2009; 5(2): 250-2.
    • (2009) Autophagy , vol.5 , Issue.2 , pp. 250-252
    • Cadwell, K.1    Patel, K.K.2    Komatsu, M.3    Hwt, V.4    Stappenbeck, T.S.5
  • 106
    • 84875892111 scopus 로고    scopus 로고
    • Autophagy as a stress-response and quality-control mechanism: Implications for cell injury and human disease
    • Murrow L, Debnath J. Autophagy as a stress-response and quality-control mechanism: implications for cell injury and human disease. Annu Rev Pathol 2013; 8: 105-37.
    • (2013) Annu Rev Pathol , vol.8 , pp. 105-137
    • Murrow, L.1    Debnath, J.2
  • 107
    • 23044463578 scopus 로고    scopus 로고
    • Runx1 prevents wasting, myofibrillar disorganization, and autophagy of skeletal muscle
    • Wang X, Blagden C, Fan J, et al. Runx1 prevents wasting, myofibrillar disorganization, and autophagy of skeletal muscle. Genes Dev 2005; 19(14): 1715-22.
    • (2005) Genes Dev , vol.19 , Issue.14 , pp. 1715-1722
    • Wang, X.1    Blagden, C.2    Fan, J.3
  • 108
    • 70449927247 scopus 로고    scopus 로고
    • Autophagy is required to maintain muscle mass
    • Masiero E, Agatea L, Mammucari C, et al. Autophagy is required to maintain muscle mass. Cell Metab 2009; 10(6): 507-15.
    • (2009) Cell Metab , vol.10 , Issue.6 , pp. 507-515
    • Masiero, E.1    Agatea, L.2    Mammucari, C.3
  • 109
    • 33744916798 scopus 로고    scopus 로고
    • Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1
    • Shibata M, Lu T, Furuya T, et al. Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1. J Biol Chem 2006; 281(20): 14474-85.
    • (2006) J Biol Chem , vol.281 , Issue.20 , pp. 14474-14485
    • Shibata, M.1    Lu, T.2    Furuya, T.3
  • 110
    • 52749093177 scopus 로고    scopus 로고
    • Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet
    • Ebato C, Uchida T, Arakawa M, et al. Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet. Cell Metab 2008; 8(4): 325-32.
    • (2008) Cell Metab , vol.8 , Issue.4 , pp. 325-332
    • Ebato, C.1    Uchida, T.2    Arakawa, M.3
  • 111
    • 52749094770 scopus 로고    scopus 로고
    • Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia
    • Jung HS, Chung KW, Won Kim J, et al. Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia. Cell Metab 2008; 8(4): 318-24.
    • (2008) Cell Metab , vol.8 , Issue.4 , pp. 318-324
    • Jung, H.S.1    Chung, K.W.2    Won, K.J.3
  • 112
    • 71649084135 scopus 로고    scopus 로고
    • Beneficial effects of Mammalian target of rapamycin inhibition on left ventricular remodeling after myocardial infarction
    • Buss SJ, Muenz S, Riffel JH, et al. Beneficial effects of Mammalian target of rapamycin inhibition on left ventricular remodeling after myocardial infarction. J Am Coll Cardiol 2009; 54(25): 2435-46.
    • (2009) J Am Coll Cardiol , vol.54 , Issue.25 , pp. 2435-2446
    • Buss, S.J.1    Muenz, S.2    Riffel, J.H.3
  • 113
    • 19244366021 scopus 로고    scopus 로고
    • Everolimus for the prevention of allograft rejection and vasculopathy in cardiactransplant recipients
    • Eisen HJ, Tuzcu EM, Dorent R, et al. Everolimus for the prevention of allograft rejection and vasculopathy in cardiactransplant recipients. N Engl J Med 2003; 349(9): 847-58.
    • (2003) N Engl J Med , vol.349 , Issue.9 , pp. 847-858
    • Eisen, H.J.1    Tuzcu, E.M.2    Dorent, R.3
  • 114
    • 84887187698 scopus 로고    scopus 로고
    • Phase I study evaluating the combination of lapatinib (a Her2/Neu and EGFR inhibitor) and everolimus (an mTOR inhibitor) in patients with advanced cancers: South West Oncology Group (SWOG) Study S0528
    • Gadgeel SM, Lew DL, Synold TW, et al. Phase I study evaluating the combination of lapatinib (a Her2/Neu and EGFR inhibitor) and everolimus (an mTOR inhibitor) in patients with advanced cancers: South West Oncology Group (SWOG) Study S0528. Cancer Chemother Pharmacol 2013; 72(5): 1089-96.
    • (2013) Cancer Chemother Pharmacol , vol.72 , Issue.5 , pp. 1089-1096
    • Gadgeel, S.M.1    Lew, D.L.2    Synold, T.W.3
  • 115
    • 84863044821 scopus 로고    scopus 로고
    • Ischemia-reperfusion injury leads to distinct temporal cardiac remodeling in normal versus diabetic mice
    • Eguchi M, Kim YH, Kang KW, et al. Ischemia-reperfusion injury leads to distinct temporal cardiac remodeling in normal versus diabetic mice. PLoS One 2012; 7(2): e30450.
    • (2012) PLoS One , vol.7 , Issue.2
    • Eguchi, M.1    Kim, Y.H.2    Kang, K.W.3
  • 116
    • 81855221944 scopus 로고    scopus 로고
    • Autophagy suppresses age-dependent ischemia and reperfusion injury in livers of mice
    • Wang JH, Ahn IS, Fischer TD, et al. Autophagy suppresses age-dependent ischemia and reperfusion injury in livers of mice. Gastroenterology 2011; 141(6): 2188-2199.e6.
    • (2011) Gastroenterology , vol.141 , Issue.6 , pp. 2188-2199
    • Wang, J.H.1    Ahn, I.S.2    Fischer, T.D.3
  • 117
    • 84877925296 scopus 로고    scopus 로고
    • Simvastatin maintains function and viability of steatotic rat livers procured for transplantation
    • Gracia-Sancho J, Garcia-Caldero H, Hide D, et al. Simvastatin maintains function and viability of steatotic rat livers procured for transplantation. J Hepatol 2013; 58(6): 1140-6.
    • (2013) J Hepatol , vol.58 , Issue.6 , pp. 1140-1146
    • Gracia-Sancho, J.1    Garcia-Caldero, H.2    Hide, D.3
  • 118
    • 84873309214 scopus 로고    scopus 로고
    • Role of reduced manganese superoxide dismutase in ischemia-reperfusion injury: A possible trigger for autophagy and mitochondrial biogenesis?
    • Parajuli N, MacMillan-Crow LA. Role of reduced manganese superoxide dismutase in ischemia-reperfusion injury: a possible trigger for autophagy and mitochondrial biogenesis? Am J Physiol Renal Physiol 2013; 304(3): F257-67.
    • (2013) Am J Physiol Renal Physiol , vol.304 , Issue.3
    • Parajuli, N.1    Macmillan-Crow, L.A.2
  • 119
    • 80555144189 scopus 로고    scopus 로고
    • Atg8 transfer from Atg7 to Atg3: A distinctive E1-E2 architecture and mechanism in the autophagy pathway
    • Taherbhoy AM, Tait SW, Kaiser SE, et al. Atg8 transfer from Atg7 to Atg3: a distinctive E1-E2 architecture and mechanism in the autophagy pathway. Mol Cell 2011; 44(3): 451-61.
    • (2011) Mol Cell , vol.44 , Issue.3 , pp. 451-461
    • Taherbhoy, A.M.1    Tait, S.W.2    Kaiser, S.E.3
  • 120
    • 0025925091 scopus 로고
    • Bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells
    • Yoshimori T, Yamamoto A, Moriyama Y, Futai M, Tashiro Y. Bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells. J Biol Chem 1991; 266(26): 17707-12.
    • (1991) J Biol Chem , vol.266 , Issue.26 , pp. 17707-17712
    • Yoshimori, T.1    Yamamoto, A.2    Moriyama, Y.3    Futai, M.4    Tashiro, Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.