-
1
-
-
34848886914
-
Autophagosome formation: Core machinery and adaptations
-
PMID:17909521
-
Xie Z, Klionsky DJ. Autophagosome formation: core machinery and adaptations. Nat Cell Biol 2007; 9:1102-9; PMID:17909521; http://dx.doi.org/10. 1038/ncb1007-1102
-
(2007)
Nat Cell Biol
, vol.9
, pp. 1102-1109
-
-
Xie, Z.1
Klionsky, D.J.2
-
2
-
-
39849109338
-
Autophagy fights disease through cellular self-digestion
-
PMID:18305538
-
Mizushima N, Levine B, Cuervo AM, Klionsky DJ. Autophagy fights disease through cellular self-digestion. Nature 2008; 451:1069-75; PMID:18305538; http://dx.doi.org/10.1038/nature06639
-
(2008)
Nature
, vol.451
, pp. 1069-1075
-
-
Mizushima, N.1
Levine, B.2
Cuervo, A.M.3
Klionsky, D.J.4
-
3
-
-
77956404377
-
Eaten alive: A history of macroautophagy
-
PMID: 20811353
-
Yang Z, Klionsky DJ. Eaten alive: a history of macroautophagy. Nat Cell Biol 2010; 12:814-22; PMID: 20811353; http://dx.doi.org/10.1038/ncb0910-814
-
(2010)
Nat Cell Biol
, vol.12
, pp. 814-822
-
-
Yang, Z.1
Klionsky, D.J.2
-
4
-
-
50249084987
-
Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum
-
PMID:18725538
-
Axe EL, Walker SA, Manifava M, Chandra P, Roderick HL, Habermann A, et al. Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. J Cell Biol 2008; 182:685-701; PMID:18725538; http://dx.doi.org/10. 1083/jcb.200803137
-
(2008)
J Cell Biol
, vol.182
, pp. 685-701
-
-
Axe, E.L.1
Walker, S.A.2
Manifava, M.3
Chandra, P.4
Roderick, H.L.5
Habermann, A.6
-
5
-
-
77952495224
-
Mitochondria supply membranes for autophagosome biogenesis during starvation
-
PMID:20478256
-
Hailey DW, Rambold AS, Satpute-Krishnan P, Mitra K, Sougrat R, Kim PK, et al. Mitochondria supply membranes for autophagosome biogenesis during starvation. Cell 2010; 141:656-67; PMID:20478256; http://dx.doi.org/10.1016/j. cell.2010.04.009
-
(2010)
Cell
, vol.141
, pp. 656-667
-
-
Hailey, D.W.1
Rambold, A.S.2
Satpute-Krishnan, P.3
Mitra, K.4
Sougrat, R.5
Kim, P.K.6
-
6
-
-
77956414236
-
The origin of the autophagosomal membrane
-
PMID: 20811355
-
Tooze SA, Yoshimori T. The origin of the autophagosomal membrane. Nat Cell Biol 2010; 12:831-5; PMID: 20811355; http://dx.doi.org/10.1038/ncb0910-831
-
(2010)
Nat Cell Biol
, vol.12
, pp. 831-835
-
-
Tooze, S.A.1
Yoshimori, T.2
-
7
-
-
77955131007
-
Plasma membrane contributes to the formation of pre-autophagosomal structures
-
PMID:20639872
-
Ravikumar B, Moreau K, Jahreiss L, Puri C, Rubinsztein DC. Plasma membrane contributes to the formation of pre-autophagosomal structures. Nat Cell Biol 2010; 12:747-57; PMID:20639872; http://dx.doi.org/10.1038/ncb2078
-
(2010)
Nat Cell Biol
, vol.12
, pp. 747-757
-
-
Ravikumar, B.1
Moreau, K.2
Jahreiss, L.3
Puri, C.4
Rubinsztein, D.C.5
-
8
-
-
11144245626
-
The role of autophagy during the early neonatal starvation period
-
PMID:15525940
-
Kuma A, Hatano M, Matsui M, Yamamoto A, Nakaya H, Yoshimori T, et al. The role of autophagy during the early neonatal starvation period. Nature 2004; 432:1032-6; PMID:15525940; http://dx.doi.org/10.1038/nature03029
-
(2004)
Nature
, vol.432
, pp. 1032-1036
-
-
Kuma, A.1
Hatano, M.2
Matsui, M.3
Yamamoto, A.4
Nakaya, H.5
Yoshimori, T.6
-
9
-
-
12944303650
-
Growth factor regulation of autophagy and cell survival in the absence of apoptosis
-
PMID:15680329
-
Lum JJ, Bauer DE, Kong M, Harris MH, Li C, Lindsten T, et al. Growth factor regulation of autophagy and cell survival in the absence of apoptosis. Cell 2005; 120:237-48; PMID:15680329; http://dx.doi.org/10.1016/j.cell.2004.11. 046
-
(2005)
Cell
, vol.120
, pp. 237-248
-
-
Lum, J.J.1
Bauer, D.E.2
Kong, M.3
Harris, M.H.4
Li, C.5
Lindsten, T.6
-
10
-
-
20344406240
-
Autophagy in metazoans: Cell survival in the land of plenty
-
PMID:15928708
-
Lum JJ, DeBerardinis RJ, Thompson CB. Autophagy in metazoans: cell survival in the land of plenty. Nat Rev Mol Cell Biol 2005; 6:439-48; PMID:15928708; http://dx.doi.org/10.1038/nrm1660
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 439-448
-
-
Lum, J.J.1
DeBerardinis, R.J.2
Thompson, C.B.3
-
11
-
-
76249127368
-
Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo
-
PMID:20080761
-
Mortensen M, Ferguson DJ, Edelmann M, Kessler B, Morten KJ, Komatsu M, et al. Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo. Proc Natl Acad Sci USA 2010; 107:832-7; PMID:20080761; http://dx.doi.org/10.1073/pnas.0913170107
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 832-837
-
-
Mortensen, M.1
Ferguson, D.J.2
Edelmann, M.3
Kessler, B.4
Morten, K.J.5
Komatsu, M.6
-
12
-
-
47049100413
-
Essential role for Nix in autophagic maturation of erythroid cells
-
PMID:18454133
-
Sandoval H, Thiagarajan P, Dasgupta SK, Schumacher A, Prchal JT, Chen M, et al. Essential role for Nix in autophagic maturation of erythroid cells. Nature 2008; 454:232-5; PMID:18454133; http://dx.doi.org/10.1038/nature07006
-
(2008)
Nature
, vol.454
, pp. 232-235
-
-
Sandoval, H.1
Thiagarajan, P.2
Dasgupta, S.K.3
Schumacher, A.4
Prchal, J.T.5
Chen, M.6
-
13
-
-
77951649035
-
The role of autophagy in tumour development and cancer therapy
-
PMID:19951459
-
Rosenfeldt MT, Ryan KM. The role of autophagy in tumour development and cancer therapy. Expert Rev Mol Med 2009; 11:e36; PMID:19951459; http://dx.doi.org/10.1017/S1462399409001306
-
(2009)
Expert Rev Mol Med
, vol.11
-
-
Rosenfeldt, M.T.1
Ryan, K.M.2
-
14
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
PMID: 21376230
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011; 144:646-74; PMID: 21376230; http://dx.doi.org/10.1016/j.cell.2011.02.013
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
15
-
-
70349459599
-
P53 and metabolism
-
PMID:19759539
-
Vousden KH, Ryan KM. p53 and metabolism. Nat Rev Cancer 2009; 9:691-700; PMID:19759539; http://dx.doi.org/10.1038/nrc2715
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 691-700
-
-
Vousden, K.H.1
Ryan, K.M.2
-
16
-
-
77951243028
-
Autophagy regulation by p53
-
PMID:20044243
-
Maiuri MC, Galluzzi L, Morselli E, Kepp O, Malik SA, Kroemer G. Autophagy regulation by p53. Curr Opin Cell Biol 2010; 22:181-5; PMID:20044243; http://dx.doi.org/10.1016/j.ceb.2009.12.001
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 181-185
-
-
Maiuri, M.C.1
Galluzzi, L.2
Morselli, E.3
Kepp, O.4
Malik, S.A.5
Kroemer, G.6
-
17
-
-
44649141966
-
Regulation of autophagy by cytoplasmic p53
-
PMID:18454141
-
Tasdemir E, Maiuri MC, Galluzzi L, Vitale I, Djavaheri-Mergny M, D'Amelio M, et al. Regulation of autophagy by cytoplasmic p53. Nat Cell Biol 2008; 10:676-87; PMID:18454141; http://dx.doi.org/10.1038/ncb1730
-
(2008)
Nat Cell Biol
, vol.10
, pp. 676-687
-
-
Tasdemir, E.1
Maiuri, M.C.2
Galluzzi, L.3
Vitale, I.4
Djavaheri-Mergny, M.5
D'Amelio, M.6
-
18
-
-
9944240863
-
Splicing DNA-damage responses to tumour cell death
-
PMID:15585169
-
Crighton D, Ryan KM. Splicing DNA-damage responses to tumour cell death. Biochim Biophys Acta 2004; 1705:3-15; PMID:15585169
-
(2004)
Biochim Biophys Acta
, vol.1705
, pp. 3-15
-
-
Crighton, D.1
Ryan, K.M.2
-
19
-
-
34248210257
-
The direct p53 target gene, FLJ11259/DRAM, is a member of a novel family of transmembrane proteins
-
PMID:17397945
-
Kerley-Hamilton JS, Pike AM, Hutchinson JA, Freemantle SJ, Spinella MJ. The direct p53 target gene, FLJ11259/DRAM, is a member of a novel family of transmembrane proteins. Biochim Biophys Acta 2007; 1769:209-19; PMID:17397945
-
(2007)
Biochim Biophys Acta
, vol.1769
, pp. 209-219
-
-
Kerley-Hamilton, J.S.1
Pike, A.M.2
Hutchinson, J.A.3
Freemantle, S.J.4
Spinella, M.J.5
-
20
-
-
68049108333
-
Analysis of DRAM-related proteins reveals evolutionarily conserved and divergent roles in the control of autophagy
-
PMID:19556885
-
O'Prey J, Skommer J, Wilkinson S, Ryan KM. Analysis of DRAM-related proteins reveals evolutionarily conserved and divergent roles in the control of autophagy. Cell Cycle 2009; 8:2260-5; PMID:19556885; http://dx.doi.org/10.4161/ cc.8.14.9050
-
(2009)
Cell Cycle
, vol.8
, pp. 2260-2265
-
-
O'Prey, J.1
Skommer, J.2
Wilkinson, S.3
Ryan, K.M.4
-
21
-
-
33745885329
-
DRAM, a p53-induced modulator of autophagy, is critical for apoptosis
-
PMID:16839881
-
Crighton D, Wilkinson S, O'Prey J, Syed N, Smith P, Harrison PR, et al. DRAM, a p53-induced modulator of autophagy, is critical for apoptosis. Cell 2006; 126:121-34; PMID:16839881; http://dx.doi.org/10.1016/j.cell.2006.05.034
-
(2006)
Cell
, vol.126
, pp. 121-134
-
-
Crighton, D.1
Wilkinson, S.2
O'Prey, J.3
Syed, N.4
Smith, P.5
Harrison, P.R.6
-
22
-
-
33846260837
-
DRAM links autophagy to p53 and programmed cell death
-
PMID:17102582
-
Crighton D, Wilkinson S, Ryan KM. DRAM links autophagy to p53 and programmed cell death. Autophagy 2007; 3:72-4; PMID:17102582
-
(2007)
Autophagy
, vol.3
, pp. 72-74
-
-
Crighton, D.1
Wilkinson, S.2
Ryan, K.M.3
-
23
-
-
20444390475
-
The discovery of split genes and RNA splicing
-
PMID: 15950867
-
Sharp PA. The discovery of split genes and RNA splicing. Trends Biochem Sci 2005; 30:279-81; PMID: 15950867; http://dx.doi.org/10.1016/j.tibs.2005.04. 002
-
(2005)
Trends Biochem Sci
, vol.30
, pp. 279-281
-
-
Sharp, P.A.1
-
24
-
-
34249056243
-
P73 regulates DRAM-independent autophagy that does not contribute to programmed cell death
-
PMID:17304243
-
Crighton D, O'Prey J, Bell HS, Ryan KM. p73 regulates DRAM-independent autophagy that does not contribute to programmed cell death. Cell Death Differ 2007; 14:1071-9; PMID:17304243; http://dx.doi.org/10.1038/sj.cdd.4402108
-
(2007)
Cell Death Differ
, vol.14
, pp. 1071-1079
-
-
Crighton, D.1
O'Prey, J.2
Bell, H.S.3
Ryan, K.M.4
-
25
-
-
0034689773
-
Role of NF-kappaB in p53-mediated programmed cell death
-
PMID:10786798
-
Ryan KM, Ernst MK, Rice NR, Vousden KH. Role of NF-kappaB in p53-mediated programmed cell death. Nature 2000; 404:892-7; PMID:10786798; http://dx.doi.org/10.1038/35009130
-
(2000)
Nature
, vol.404
, pp. 892-897
-
-
Ryan, K.M.1
Ernst, M.K.2
Rice, N.R.3
Vousden, K.H.4
-
26
-
-
10744221485
-
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2
-
PMID:14704432
-
Vassilev LT, Vu BT, Graves B, Carvajal D, Podlaski F, Filipovic Z, et al. In vivo activation of the p53 pathway by small-molecule antagonists of MDM2. Science 2004; 303:844-8; PMID:14704432; http://dx.doi.org/10.1126/science. 1092472
-
(2004)
Science
, vol.303
, pp. 844-848
-
-
Vassilev, L.T.1
Vu, B.T.2
Graves, B.3
Carvajal, D.4
Podlaski, F.5
Filipovic, Z.6
-
27
-
-
67650751080
-
Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes
-
PMID:19373242
-
Galluzzi L, Aaronson SA, Abrams J, Alnemri ES, Andrews DW, Baehrecke EH, et al. Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell Death Differ 2009; 16:1093-107; PMID:19373242; http://dx.doi.org/10.1038/cdd.2009.44
-
(2009)
Cell Death Differ
, vol.16
, pp. 1093-1107
-
-
Galluzzi, L.1
Aaronson, S.A.2
Abrams, J.3
Alnemri, E.S.4
Andrews, D.W.5
Baehrecke, E.H.6
-
28
-
-
0027451668
-
P53-dependent apoptosis modulates the cytotoxicity of anticancer agents
-
PMID:8402885
-
Lowe SW, Ruley HE, Jacks T, Housman DE. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 1993; 74:957-67; PMID:8402885; http://dx.doi.org/10.1016/0092-8674(93)90719-7
-
(1993)
Cell
, vol.74
, pp. 957-967
-
-
Lowe, S.W.1
Ruley, H.E.2
Jacks, T.3
Housman, D.E.4
-
29
-
-
77952827569
-
Oncogene-induced sensitization to chemotherapy-induced death requires induction as well as deregulation of E2F1
-
PMID:20460519
-
Helgason GV, O'Prey J, Ryan KM. Oncogene-induced sensitization to chemotherapy-induced death requires induction as well as deregulation of E2F1. Cancer Res 2010; 70:4074-80; PMID:20460519; http://dx.doi.org/10.1158/0008-5472. CAN-09-2876
-
(2010)
Cancer Res
, vol.70
, pp. 4074-4080
-
-
Helgason, G.V.1
O'Prey, J.2
Ryan, K.M.3
-
30
-
-
0034329418
-
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
-
PMID:11060023
-
Kabeya Y, Mizushima N, Ueno T, Yamamoto A, Kirisako T, Noda T, et al. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 2000; 19:5720-8; PMID:11060023; http://dx.doi.org/10.1093/emboj/19.21.5720
-
(2000)
EMBO J
, vol.19
, pp. 5720-5728
-
-
Kabeya, Y.1
Mizushima, N.2
Ueno, T.3
Yamamoto, A.4
Kirisako, T.5
Noda, T.6
-
31
-
-
19444382327
-
The dynamics of autophagy visualized in live cells
-
PMID:16874023
-
Bampton ETW, Goemans CG, Niranjan D, Mizushima N, Tolkovsky AM. The dynamics of autophagy visualized in live cells. Autophagy 2005; 1:23-36; PMID:16874023; http://dx.doi.org/10.4161/auto.1.1.1495
-
(2005)
Autophagy
, vol.1
, pp. 23-36
-
-
Bampton, E.T.W.1
Goemans, C.G.2
Niranjan, D.3
Mizushima, N.4
Tolkovsky, A.M.5
-
32
-
-
33748651894
-
DNA-binding independent cell death from a minimal proapoptotic region of E2F-1
-
PMID:16652153
-
Bell LA, O'Prey J, Ryan KM. DNA-binding independent cell death from a minimal proapoptotic region of E2F-1. Oncogene 2006; 25:5656-63; PMID:16652153; http://dx.doi.org/10.1038/sj.onc.1209580
-
(2006)
Oncogene
, vol.25
, pp. 5656-5663
-
-
Bell, L.A.1
O'Prey, J.2
Ryan, K.M.3
-
33
-
-
3042780178
-
Loss of nuclear factor-kappaB is tumor promoting but does not substitute for loss of p53
-
PMID:15231649
-
Ryan KM, O'Prey J, Vousden KH. Loss of nuclear factor-kappaB is tumor promoting but does not substitute for loss of p53. Cancer Res 2004; 64:4415-8; PMID:15231649; http://dx.doi.org/10.1158/0008-5472.CAN-04-1474
-
(2004)
Cancer Res
, vol.64
, pp. 4415-4418
-
-
Ryan, K.M.1
O'Prey, J.2
Vousden, K.H.3
-
34
-
-
34147190124
-
A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo
-
PMID:17347683
-
Bell HS, Dufes C, O'Prey J, Crighton D, Bergamaschi D, Lu X, et al. A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo. J Clin Invest 2007; 117:1008-18; PMID:17347683; http://dx.doi.org/10.1172/ JCI28920
-
(2007)
J Clin Invest
, vol.117
, pp. 1008-1018
-
-
Bell, H.S.1
Dufes, C.2
O'Prey, J.3
Crighton, D.4
Bergamaschi, D.5
Lu, X.6
-
35
-
-
0032478271
-
A simplified system for generating recombinant adenoviruses
-
PMID:9482916
-
He TC, Zhou S, da Costa LT, Yu J, Kinzler KW, Vogelstein B. A simplified system for generating recombinant adenoviruses. Proc Natl Acad Sci USA 1998; 95:2509-14; PMID:9482916; http://dx.doi.org/10.1073/pnas.95.5.2509
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 2509-2514
-
-
He, T.C.1
Zhou, S.2
Da Costa, L.T.3
Yu, J.4
Kinzler, K.W.5
Vogelstein, B.6
-
36
-
-
0027142106
-
A single-step staining procedure for the detection and sorting of unfixed apoptotic thymocytes
-
PMID:7510545
-
Pellicciari C, Manfredi AA, Bottone MG, Schaack V, Barni S. A single-step staining procedure for the detection and sorting of unfixed apoptotic thymocytes. Eur J Histochem 1993; 37:381-90; PMID:7510545
-
(1993)
Eur J Histochem
, vol.37
, pp. 381-390
-
-
Pellicciari, C.1
Manfredi, A.A.2
Bottone, M.G.3
Schaack, V.4
Barni, S.5
-
37
-
-
0035199161
-
FENS-1 and DFCP1 are FYVE domain-containing proteins with distinct functions in the endosomal and Golgi compartments
-
PMID:11739631
-
Ridley SH, Ktistakis N, Davidson K, Anderson KE, Manifava M, Ellson CD, et al. FENS-1 and DFCP1 are FYVE domain-containing proteins with distinct functions in the endosomal and Golgi compartments. J Cell Sci 2001; 114:3991-4000; PMID:11739631
-
(2001)
J Cell Sci
, vol.114
, pp. 3991-4000
-
-
Ridley, S.H.1
Ktistakis, N.2
Davidson, K.3
Anderson, K.E.4
Manifava, M.5
Ellson, C.D.6
-
38
-
-
80655124404
-
The cyclin-dependent kinase PITSLRE/CDK11 is required for successful autophagy
-
In press. PMID:21808150
-
Wilkinson S, Croft DR, O'Prey J, Meedendorp A, O'Prey M, Dufes C, et al. The cyclin-dependent kinase PITSLRE/CDK11 is required for successful autophagy. Autophagy 2011. In press. PMID:21808150
-
(2011)
Autophagy
-
-
Wilkinson, S.1
Croft, D.R.2
O'Prey, J.3
Meedendorp, A.4
O'Prey, M.5
Dufes, C.6
|