Geranylgeranyl transferase 1 modulates autophagy and apoptosis in human airway smooth muscle

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 302, Issue 4, 2012, Pages

  Ghavami, Saeid ^a,b   Mutawe, Mark M ^a,b   Schaafsma, Dedmer ^a,b   Yeganeh, Behzad ^a,b   Unruh, Helmut ^a   Klonisch, Thomas ^a   Halayko, Andrew J ^a,b  

^a UNIVERSITY OF MANITOBA   (Canada)

^b MANITOBA INSTITUTE OF CHILD HEALTH   (Canada)

Author keywords

Cell death; GGTi 298; GTPase; p53; Rho

Indexed keywords

AUTOPHAGY PROTEIN 5; AUTOPHAGY PROTEIN 7; BAFILOMYCIN A1; CASPASE; DAMAGE REGULATED AUTOPHAGY MODULATOR PROTEIN; DNA; GERANYLGERANYL TRANSFERASE 1; GERANYLTRANSFERASE; GGTI 298; PIFITHRIN ALPHA; PROTEIN NOXA; PROTEIN P53; REGULATOR PROTEIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

AIRWAY SMOOTH MUSCLE CELL; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL VIABILITY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DNA CONTENT; ENZYME ACTIVATION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; LYSOSOME; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMOOTH MUSCLE FIBER; TRANSMISSION ELECTRON MICROSCOPY; UPREGULATION;

ALKYL AND ARYL TRANSFERASES; APOPTOSIS; AUTOPHAGY; BENZAMIDES; BENZOTHIAZOLES; BRONCHI; CELL SURVIVAL; CELLS, CULTURED; FARNESYLTRANSTRANSFERASE; HUMANS; MYOCYTES, SMOOTH MUSCLE; PRIMARY CELL CULTURE; SIGNAL TRANSDUCTION; TOLUENE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84857004809     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00312.2011     Document Type: Article

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