Nanoparticle enabled drug delivery across the blood brain barrier: In vivo and in vitro models, opportunities and challenges

Current Pharmaceutical Biotechnology

Volumn 14, Issue 14, 2013, Pages 1201-1212

  Gidwani, Meeta ^a   Singh, Ajay V ^a  

^a RENSSELAER POLYTECHNIC INSTITUTE   (United States)

Author keywords

Blood brain barrier; Endothelial cells; Nanoparticles; Polysorbate 80; Teer

Indexed keywords

ACRYLIC ACID METHYL ESTER; AMITRIPTYLINE; APOLIPOPROTEIN B; APOLIPOPROTEIN E; CAMPTOTHECIN; COUMARIN; DELAVIRDINE; DOMPERIDONE; ENBUCRILATE; ETOPOSIDE; KYOTORPHIN; LACTOFERRIN; LEUCINE ENKEPHALIN [2 DEXTRO ALANINE 6 ARGININE]; LEUCYLSERYLALANYLLEUCINE; LOPERAMIDE; LOW DENSITY LIPOPROTEIN; MACROGOL; MAGNETIC NANOPARTICLE; MATRIGEL; METHACRYLIC ACID METHYL ESTER; METHOTREXATE; NANOPARTICLE; PENICILLAMINE; POLYSORBATE 80; RIVASTIGMINE; SAQUINAVIR; STAVUDINE; TACRINE; TRANSFERRIN RECEPTOR; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ALZHEIMER DISEASE; ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; BRAIN DISEASE; COCULTURE; DRUG DELIVERY SYSTEM; DRUG PENETRATION; DRUG TARGETING; ELECTRIC RESISTANCE; ENDOTHELIUM CELL; HIGH INTENSITY FOCUSED ULTRASOUND; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; NANOPROBE; NEOPLASM; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OPSONIZATION; PARTICLE SIZE; RETICULOENDOTHELIAL SYSTEM; SURFACE PROPERTY; TRANSMISSION ELECTRON MICROSCOPY; ANIMAL; CENTRAL NERVOUS SYSTEM DISEASES; CULTURE TECHNIQUE; METABOLISM;

ANIMALS; BLOOD-BRAIN BARRIER; CELL CULTURE TECHNIQUES; CENTRAL NERVOUS SYSTEM DISEASES; DRUG DELIVERY SYSTEMS; HUMANS; NANOPARTICLES;

EID: 84904042918     PISSN: 13892010     EISSN: 18734316     Source Type: Journal    
DOI: 10.2174/1389201015666140508122558     Document Type: Article

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