Long-circulating pegylated polycyanoacrylate nanoparticles as new drug carrier for brain delivery

Pharmaceutical Research

Volumn 18, Issue 8, 2001, Pages 1157-1166

  Calvo, P ^a   Gouritin, B ^a   Chacun, H ^a   Desmaile, D ^b   D'Angelo, J ^b   Noel, J P ^c   Georgin, D ^c   Fattal, E ^a   Andreux, J P ^a   Couvreur, P ^a  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b CNRS   (France)

^c CEA SACLAY   (France)

Author keywords

Brain targeting; PEGylated nanoparticles; Polysorbate 80; Surfactant coating

Indexed keywords

CARBON 14; CYANOACRYLATE DERIVATIVE; DRUG CARRIER; NANOPARTICLE; NEUROPEPTIDE; POLOXAMER; POLOXAMINE 908; POLYSORBATE 80; POLY[METHOXYPOLY(ETHYLENE GLYCOL)CYANOACRYLATE CO HEXADECYL CYANOACETATE]; SORBITAN OLEATE; SUCROSE; SYNPERONIC; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD BRAIN BARRIER; BRAIN VENTRICLE; CAPILLARY ENDOTHELIUM; CELL INTERACTION; CHOROID PLEXUS; CONTROLLED STUDY; DRUG BRAIN LEVEL; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG FORMULATION; ENDOTHELIUM CELL; EPENDYMA CELL; FLUORESCENCE MICROSCOPY; MALE; MOUSE; NONHUMAN; PIA MATER; PRIORITY JOURNAL; QUANTITATIVE ASSAY; RADIOACTIVITY; RAT; SURFACE PROPERTY;

EID: 0034812929     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1010931127745     Document Type: Article

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