Magnetic resonance monitoring of focused ultrasound/magnetic nanoparticle targeting delivery of therapeutic agents to the brain

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 34, 2010, Pages 15205-15210

  Liu, Hao Li ^a,b   Hua, Mu Yi ^a   Yang, Hung Wei ^a   Huang, Chiung Yin ^c   Chu, Po N ^a   Wu, Jia Shin ^a   Tseng, I Chou ^c   Wang, Jiun Jie ^a   Yen, Tzu Chen ^b   Chen, Pin Yuan ^a,c   Wei, Kuo Chen ^c  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^c CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

Author keywords

Blood brain barrier; Brain drug delivery; Focused ultrasound; Magnetic nanoparticles; Magnetic targeting

Indexed keywords

DOXORUBICIN; EPIRUBICIN; MAGNETIC NANOPARTICLE; ANTINEOPLASTIC ANTIBIOTIC; CONTRAST MEDIUM; METAL NANOPARTICLE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN TUMOR; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG STRUCTURE; ECHOGRAPHY; IC 50; IMAGE ANALYSIS; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RAT; ANIMAL; MAGNETISM; METHODOLOGY; SPRAGUE DAWLEY RAT; TRANSMISSION ELECTRON MICROSCOPY; ULTRASOUND THERAPY; ULTRASTRUCTURE; VASCULARIZATION;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BLOOD-BRAIN BARRIER; BRAIN NEOPLASMS; CONTRAST MEDIA; DRUG DELIVERY SYSTEMS; EPIRUBICIN; MAGNETIC RESONANCE IMAGING; MAGNETICS; METAL NANOPARTICLES; MICROSCOPY, ELECTRON, TRANSMISSION; RATS; RATS, SPRAGUE-DAWLEY; ULTRASONIC THERAPY;

EID: 77957013817     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1003388107     Document Type: Article

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