Transferrin-grafted catanionic solid lipid nanoparticles for targeting delivery of saquinavir to the brain

Journal of the Taiwan Institute of Chemical Engineers

Volumn 45, Issue 3, 2014, Pages 755-763

  Kuo, Yung Chih ^a   Wang, Li Jung ^a  

^a NATIONAL CHUNG CHENG UNIVERSITY   (Taiwan)

Author keywords

Blood brain barrier; Catanionic surfactant; Human brain microvascular endothelial cell; Saquinavir; Solid lipid nanoparticle; Transferrin

Indexed keywords

BLOOD; BLOOD VESSELS; BRAIN; ENDOTHELIAL CELLS; GRAFTING (CHEMICAL); NANOPARTICLES;

BLOOD-BRAIN BARRIER; CATANIONIC SURFACTANTS; HUMAN BRAIN-MICROVASCULAR ENDOTHELIAL CELLS; SAQUINAVIR; SOLID LIPID NANOPARTICLE (SLN); TRANSFERRIN;

SURFACE ACTIVE AGENTS;

EID: 84895930422     PISSN: 18761070     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jtice.2013.09.024     Document Type: Article

References (71)

1. Pan W., Kastin A.J. Adipokines and the blood-brain barrier. Peptides 2007, 28:1317-1330.
2. Pardridge W.M. The blood-brain barrier: bottleneck in brain drug development. NeuroRx 2005, 2:3-14.
3. Kuo Y.C., Lu C.H. Modulation of efflux proteins by electromagnetic field for delivering azidothymidine and saquinavir into the brain. Colloids Surf B 2012, 91:291-295.
4. Wolburg H., Lippoldt A. Tight junctions of the blood-brain barrier: development, composition and regulation. Vascul Pharmacol 2002, 38:323-337.
5. Nag S., Begley D.J. Blood-brain barrier, exchange of metabolites and gases. Pathology and genetics: cerebrovascular diseases 2005, 22-29. ISN Neuropath Press, Basel. H. Kalimo (Ed.).
6. Sun H., Dai H., Shaik N., Elmquist W.F. Drug efflux transporters in the CNS. Adv Drug Deliv Rev 2003, 55:83-105.
7. Golden P.L., Pollack G.M. Blood-brain barrier efflux transport. J Pharm Sci 2003, 92:1739-1753.
8. Abbott N.J. Evidence for bulk flow of brain interstitial fluid: significance for physiology and pathology. Neurochem Int 2004, 45:545-552.
9. Abbott N.J. Dynamics of CNS barriers: evolution, differentiation and modulation. Cell Mol Neurobiol 2005, 25:5-23.
10. Kuo Y.C., Yu H.W. Transport of saquinavir across human brain-microvascular endothelial cells by poly(lactide-co-glycolide) nanoparticles with surface poly-(γ-glutamic acid). Int J Pharm 2011, 416:365-375.
11. Kuo Y.C., Lee C.L. Methylmethacrylate-sulfopropylmethacrylate nanoparticles with surface RMP-7 for targeting delivery of antiretroviral drugs across the blood-brain barrier. Colloids Surf B 2012, 90:75-82.
12. Gabathuler R. Approaches to transport therapeutic drugs across the blood-brain barrier to treat brain diseases. Neurobiol Dis 2010, 37:48-57.
13. Prigent S.A., Stanley K.K., Siddle K. Identification of epitopes on the human insulin receptor reacting with rabbit polyclonal antisera and mouse monoclonal antibodies. J Biol Chem 1990, 265:9970-9977.
14. Kuo Y.C., Chung C.Y. Transcytosis of CRM197-grafted polybutylcyanoacrylate nanoparticles for delivering zidovudine across human brain-microvascular endothelial cells. Colloids Surf B 2012, 91:242-249.
15. Voinea M., Dragomir E., Manduteanu I., Simionescu M. Binding and uptake of transferring-bound liposomes targeted to transferrin receptors of endothelial cells. Vascul Pharmacol 2002, 39:13-20.
16. Ke Y., Qian Z.M. Brain iron metabolism: neurobiology and neurochemistry. Prog Neurobiol 2007, 83:149-173.
17. Ponka P., Lok C.N. The transferrin receptor: role in health and disease. Int J Biochem Cell Biol 1999, 31:1111-1137.
18. Anabousi S., Laue M., Lehr C.M., Bakowsky U., Ehrhardt C. Assessing transferrin modification of liposomes by atomic force microscopy and transmission electron microscopy. Eur J Pharm Biopharm 2005, 60:295-303.
19. Gu M.Q., Yuan X.B., Kang C.S., Zhao Y.H., Tian N.J., Pu P.Y., et al. Surface biofunctionalization of PLA nanoparticles through amphiphilic polysaccharide coating and ligand coupling: evaluation of biofunctionalization and drug releasing behavior. Carbohydr Polym 2007, 67:417-426.
20. Li Y., Ogris M., Wagner E., Pelisek J., Ruffer M. Nanoparticles bearing polyethyleneglycol-coupled transferrin as gene carriers: preparation and in vitro evaluation. Int J Pharm 2003, 259:93-101.
21. Burdo J.R., Antonetti D.A., Wolpert E.B., Connor J.R. Mechanisms and regulation of transferring and iron transport in a model blood-brain barrier system. Neuroscience 2003, 121:883-890.
22. Sahoo S.K., Labhasetwar V. Enhanced antiproliferative activity of transferrin-conjugated paclitaxel-loaded nanoparticles is mediated via sustained intracellular drug retention. Mol Pharm 2005, 5:373-383.
23. Kuo Y.C., Chen I.C. Evaluation of surface charge density and surface potential by electrophoretic mobility for solid lipid nanoparticles and human brain-microvascular endothelial cells. J Phys Chem B 2007, 111:11228-11236.
24. Kuo Y.C., Su F.L. Transport of stavudine, delavirdine, and saquinavir across the blood-brain barrier by polybutylcyanoacrylate, methylmethacrylate-sulfopropylmethacrylate, and solid lipid nanoparticles. Int J Pharm 2007, 340:143-152.
25. Kuo Y.C., Lu C.H. Effect of human astrocytes on the characteristics of human brain-microvascular endothelial cells in the blood-brain barrier. Colloids Surf B 2011, 86:225-231.
26. Kuo Y.C., Lu C.H. Regulation of endocytosis into human brain-microvascular endothelial cells by inhibition of efflux proteins. Colloids Surf B 2011, 87:139-145.
27. Kuo Y.C., Yu H.W. Expression of ornithine decarboxylase during the transport of saquinavir across the blood-brain barrier using composite polymeric nanocarriers under an electromagnetic field. Colloids Surf B 2011, 88:627-634.
28. Kuo Y.C., Kuo C.Y. Electromagnetic interference in the permeability of saquinavir across the blood-brain barrier using nanoparticulate carriers. Int J Pharm 2008, 351:271-281.
29. Hac-Wydro K., Wydro P. The influence of fatty acids on model cholesterol/phopholipid membranes. Chem Phys Lipids 2007, 150:66-81.
30. Maiti K., Bhattacharya S.C., Moulik S.P., Panda A.K. Physicochemistry of the binary interacting mixtures of cetylpyridinium chloride (CPC) and sodium dodecylsulfate (SDS) with special reference to the catanionic ion-pair (coacervate) behavior. Colloids Surf A 2010, 355:88-98.
31. Kuo Y.C., Lin S.C. Effect of glutamate on the electrical properties of cationic solid lipid nanoparticles containing stearylamine and dioctadecyldimethyl ammonium bromide. J Phys Chem B 2008, 112:4454-4460.
32. Kuo Y.C., Lin C.W. Impact of arginine-modified solid lipid nanoparticles on the membrane charge of human brain-microvascular endothelial cells. Colloids Surf B 2009, 72:201-207.
33. Lopez-Fontan J.L., Blanco E., Ruso J.M., Prieto M., Schulz P.C., Sarmiento F. The aqueous catanionic system sodium perfluorooctanoate-dodecyltrimethylammonium bromide at low concentration. J Colloid Interface Sci 2007, 312:425-431.
34. Aiello C., Andreozzi P., Mesa C.L., Risuleo G. Biological activity of SDS-CTAB cat-anionic vesicles in cultured cells and assessment of their cytotoxicity ending in apoptosis. Colloids Surf B 2010, 78:149-154.
35. Liu Y.S., Wen C.F., Yang Y.M. Development of ethosome-like catanionic vesicles for dermal drug delivery. J Taiwan Inst Chem Eng 2012, 43:830-838.
36. Gaumet M., Vargas A., Gurny R., Delie F. Nanoparticles for drug delivery: the need for precision in reporting particle size parameters. Eur J Pharm Biopharm 2008, 69:1-9.
37. Wan F., You J., Sun Y., Zhang X.G., Cui F.D., Du Y.Z., et al. Studies on PEG-modified SLNs loading vinorelbine bitartrate (I): preparation and evaluation in vitro. Int J Pharm 2008, 359:104-110.
38. Kuo Y.C., Chen H.H. Effect of nanoparticulate polybutylcyanoacrylate and methylmethacrylate-sulfopropylmethacrylate on the permeability of zidovudine and lamivudine across the in vitro blood-brain barrier. Int J Pharm 2006, 327:160-169.
39. Hou D.Z., Xie C.S., Huang K.J., Zhu C.H. The production and characteristics of solid lipid nanoparticles (SLNs). Biomaterials 2003, 24:1781-1785.
40. Kuo Y.C., Ko H.F. Targeting delivery of saquinavir to the brain using 83-14 monoclonal antibody-grafted solid lipid nanoparticles. Biomaterials 2013, 34:4818-4830.
41. Kuo Y.C., Chen H.H. Entrapment and release of saquinavir using novel cationic solid lipid nanoparticles. Int J Pharm 2009, 365:206-213.
42. Souto E.B., Anselmi C., Centini M., Muller R.H. Preparation and characterization of n-dodecyl-ferulate-loaded solid lipid nanoparticles. Int J Pharm 2005, 295:261-268.
43. Muller R.H., Mader K., Gohla S. Solid lipid nanoparticles (SLN) for controlled drug delivery-a review of the state of the art. Eur J Pharm Biopharm 2000, 50:161-177.
44. Teeranachaideekul V., Muller R.H., Junyaprasertv V.B. Encapsulation of ascorbyl palmitate in nanostructured lipid carriers (NLC) - effects of formulation parameters on physicochemical stability. Int J Pharm 2007, 340:198-206.
45. Souto E.B., Mehnert W., Muller R.H. Polymorphic behaviour of Compritol 888 ATO as bulk lipid and as SLN and NLC. J Microencapsul 2006, 23:417-433.
46. Kim B.D., Na K., Choi H.K. Preparation and characterization of solid lipid nanoparticles (SLN) made of cacao butter and curdlan. Eur J Pharm Sci 2005, 24:199-205.
47. Kuo Y.C., Shih-Huang C.Y. Solid lipid nanoparticles carrying chemotherapeutic drug across the blood-brain barrier through insulin receptor-mediated pathway. J Drug Target 2013, 21:730-738.
48. Vivek K., Reddy H., Murthy R.S.R. Investigations of the effect of the lipid matrix on drug entrapment, in vitro release, and physical stability of olanzapine-loaded solid lipid nanoparticles. AAPS PharmSciTech 2007, 8:E1-E9.
49. Doktorovova S., Shegokar R., Rakovsky E., Gonzalez-Mira E., Lopes C.M., Silva A.M., et al. Cationic solid lipid nanoparticles (cSLN): structure, stability and DNA binding capacity correlation studies. Int J Pharm 2011, 420:341-349.
50. Vighi E., Ruozi B., Montanari M., Battini R., Leo E. Re-dispersible cationic solid lipid nanoparticles (SLNs) freeze-dried without cryoprotectors: characterization and ability to bind the pEGFP-plasmid. Eur J Pharm Biopharm 2007, 67:320-328.
51. Chang J., Jallouli Y., Kroubi M., Yuan X.B., Feng W., Kang C.S., et al. Characterization of endocytosis of transferrin-coated PLGA nanoparticles by the blood-brain barrier. Int J Pharm 2009, 379:285-292.
52. Muller R.H., Maassen S., Weyhers H., Specht F., Lucks J.S. Cytotoxicity of magnetite-loaded polylactide, polylactide/glycolide particles and solid lipid nanoparticles. Int J Pharm 1996, 138:85-94.
53. Kim S.B., Ozawa T., Tao H., Umezawa Y. A proinflammatory cytokine sensor cell for assaying inflammatory activities of nanoparticles. Anal Biochem 2007, 362:148-150.
54. Yuan H., Miao J., Du Y.Z., You J., Hu F.Q., Zeng S. Cellular uptake of solid lipid nanoparticles and cytotoxicity of encapsulated paclitaxel in A549 cancer cells. Int J Pharm 2008, 348:137-145.
55. Kuo Y.C., Liang C.T. Inhibition of human brain malignant glioblastoma cells using carmustine-loaded catanionic solid lipid nanoparticles with surface anti-epithelial growth factor receptor. Biomaterials 2011, 32:3340-3350.
56. Kuo Y.C., Liang C.T. Catanionic solid lipid nanoparticles carrying doxorubicin for inhibiting the growth of U87MG cells. Colloids Surf B 2011, 85:131-137.
57. Kuo Y.C., Wang C.C. Electrophoresis of human brain microvascular endothelial cells with uptake of cationic solid lipid nanoparticles: effect of surfactant composition. Colloids Surf B 2010, 76:286-291.
58. Jones C.F., Grainger D.W. In vitro assessments of nanomaterial toxicity. Adv Drug Deliv Rev 2009, 61:438-456.
59. Tabbat K., Sameti M., Olbrich C., Muller R.H., Lehr C.M. Effect of cationic lipid and matrix lipid composition on solid lipid nanoparticle-mediated gene transfer. Eur J Pharm Biopharm 2004, 57:155-162.
60. Weyenberg W., Filev P., Van den Plas D., Vandervoot J., Smet K.D., Sollie P., et al. Cytotoxicity of submicron emulsions and solid lipid nanoparticles for dermal application. Int J Pharm 2007, 337:291-298.
61. Gaillard P.J., de Boer A.G. Relationship between permeability status of the blood-brain barrier and in vitro permeability coefficient of a drug. Eur J Pharm Sci 2000, 12:95-102.
62. Abbott N.J. Astrocyte-endothelial interactions and blood-brain barrier permeability. J Anat 2002, 200:629-638.
63. Flecher N.F., Brayden D.J., Brankin B., Worrall S., Callanan J.J. Growth and characterisation of a cell culture model of the feline blood-brain barrier. Vet Immunol Immunopathol 2006, 109:233-244.
64. Wagner E., Curiel D., Cotton M. Delivery of drugs, proteins and genes into cells using transferrin as a ligand for receptor-mediated endocytosis. Adv Drug Deliv Rev 1994, 14:113-135.
65. Griffiths P.D., Crossman A.R. Autoradiography of transferrin receptors in the human brain. Neurosci Lett 1996, 211:53-56.
66. Qian Z.M., Li H., Sun H., Ho K. Targeted drug delivery via the transferrin receptor-mediated endocytosis pathway. Pharmacol Rev 2002, 54:561-587.
67. Nakase I., Gallis B., Takatani-Nakase T., Oh S., Lacoste E., Singh N.P., et al. Transferrin receptor-dependent cytotoxicity of artemisinin-transferrin conjugates on prostate cancer cells and induction of apoptosis. Cancer Lett 2009, 274:290-298.
68. Kuo Y.C., Lin P.I., Wang C.C. Targeting nevirapine delivery across human brain microvesscular endothelial cells using transferrin-grafted poly(lactide-co-glycolide) nanoparticles. Nanomedicine 2011, 6:1011-1026.
69. Scholer N., Hahn H., Muller R.H., Liesenfeid O. Effect of lipid matrix and size of solid lipid nanoparticles (SLN) on the viability and cytokine production of macrophages. Int J Pharm 2002, 231:167-176.
70. Kuo Y.C., Chen H.H. Effect of electromagnetic field on endocytosis of cationic solid lipid nanoparticles by human brain-microvascular endothelial cells. J Drug Target 2010, 18:447-456.
71. Stonestreet B.S., Patlak C.S., Pettigrew K.D., Reilly C.B., Cserr H.F. Ontogeny of blood-brain barrier function in ovine fetuses, lambs, and adults. Am J Physiol-Regul Integr Comp Physiol 1996, 271:1594-1601.