Evaluation of effect of charge and lipid coating on ability of 60-nm nanoparticles to cross an in vitro model of the blood-brain barrier

Journal of Pharmacology and Experimental Therapeutics

Volumn 291, Issue 3, 1999, Pages 1017-1022

  Fenart, L ^a   Casanova, A ^a,b   Dehouck, B ^a   Duhem, C ^a   Slupek, S ^a   Cecchelli, Roméo ^a,c   Betbeder, D ^a,b  

^a INSTITUT PASTEUR DE LILLE   (France)

^b Biovector Therapeutics   (France)

^c UNIVERSITÉ D'ARTOIS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; CHOLESTEROL; DIPALMITOYLPHOSPHATIDYLCHOLINE; LIPID; MALTODEXTRIN; NANOPARTICLE;

ANIMAL CELL; ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; CAPILLARY ENDOTHELIUM; CATTLE; CELL INTERACTION; COCULTURE; ERYTHROCYTE; LIPID BILAYER; NONHUMAN; PERMEABILITY; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN TRANSPORT; RAT; TRANSCYTOSIS;

ANIMALS; ASTROCYTES; BLOOD-BRAIN BARRIER; CATTLE; CELLS, CULTURED; COCULTURE TECHNIQUES; ENDOTHELIUM; LIPOSOMES; MICROSCOPY, FLUORESCENCE; MICROSPHERES; PHOSPHOLIPIDS; POLYSACCHARIDES; RATS;

EID: 0032732345     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Arfors KE and Hint HC (1973) Studies of the microcirculation using fluorescent dextran. Microvasc Res 3:440-444.
2. Bartlett GRJ (1959) Phosphorus assay in column chromatography. J Biol Chem 234:466-468.
3. Betbeder D, Davrinche C, Davignon JL and Prieur E (1996) Method for enhancing immunogenicity, product obtained and pharmaceutical composition. Patent number WO 96/06638.
4. Bickel U, Yoshikawa T, Landaw EM, Faull KF and Pardridge WM (1993) Pharmacologic effects in vivo in brain by vector-mediated peptide drug delivery. Proc Natl Acad Sci USA 90:2618-2622.
5. Bornstein MB (1958) Reconstituted rat tail collagen used as substrate for time tissue cultures on coverslips in Maximow slides and roller tubes. Lab Invest 7:134-139.
6. Dehouck MP, Dehouck B, Schluep C, Lemaire M and Cecchelli R (1995) Drug transport to the brain: Comparison between in vitro and in vivo models of the blood-brain barrier. Eur J Pharmacol 3:357-365.
7. Dehouck B, Fenart L, Dehouck MP, Pierce A, Torpier G and Cecchelli R (1997) A new function for the LDL receptor: Transcytosis of LDL across the blood-brain barrier. J Cell Biol 138:877-889.
8. Dehouck MP, Jolliet-Riant P, Brée F, Fruchart JC, Cecchelli R and Tillement JP (1992) Drug transfer across the blood-brain barrier: In vitro and in vivo models. J Neurochem 58:1790-1797.
9. Dehouck MP, Méresse S, Delorme P, Fruchart JC and Cecchelli R (1990) An easier, reproducible and mass-production method to study the blood-brain barrier "in vitro". J Neurochem 54:1798-1801.
10. Descamps L, Dehouck MP, Torpier G and Cecchelli R (1996) Receptor-mediated transcytosis of transferrin through blood-brain barrier endothelial cells. Am J Physiol 270:H1149-H1158.
11. Eytan GD, Broza R, Notsani BE, Dachir D and Gad AE (1982) Interaction of acidic liposomes with red blood cells. Induction of endocytosis and shedding of particles. Biochem Biophys Acta 689:464-474.
12. Fillebeen C, Descamps L, Dehouck MP, Fenart L, Benaïssa M, Spick G, Cecchelli R and Pierce A (1999) Receptor mediated transcytosis of lactoferrin through the blood-brain barrier. J Biol Chem 274:7011-7017.
13. Friden PM, Walus LR, Watson P, Doctrow SR, Kozarich JW, Bäckman C, Bergman H, Hoffer B, Bloom F and Granholm AC (1993) Blood-brain barrier penetration and "in vivo" activity of an NGF conjugate. Science (Wash DC) 259:373-377.
14. Ghitescu L and Bendayan M (1992) Transendothelial transport of serum albumin: A quantitative immunocytochemical study. J Cell Biol 117:745-755.
15. Hirase T, Staddon JM, Saitou M, Ando-Akatsuka Y, Itoh M, Furuse M, Fujimoto K, Tsukita S and Rubin LL (1997) Occludin as a possible determinant of tight junction permeability in endothelial cells. J Cell Sci 110:1603-1613.
16. Illum L and Davies SS (1983) Effect of nonionic surfactant poloxamer 338 on the fate and deposition of polystyrene microspheres following intravenous administration. J Pharm Sci 72:1086-1090.
17. Inumara T, Nomura T, Bartus RT and Black KL (1994) Intracarotid infusion of RMP-7, a bradykiuin analog: A method for selective drug delivery to brain tumors. J Neurosurg 81:752-758.
18. Kordower JH, Winn SR, Liu YT, Mufson EJ, Sladek JR Jr, Hammang JP, Baetge EE and Emerich DF (1994) The aged monkey basal forebrain: Rescue and sprouting of axotomized basal forebrain neurons after grafts of encapsulated cells secreting human nerve growth factor. Proc Natl Acad Sci USA 91:10898-10902.
19. Krewson CE, Klarman ML and Saltzman WM (1995) Distribution of nerve growth factor following direct delivery to brain interstitium. Brain Res 680:196-206.
20. Major M, Prieur E, Tocanne JF, Betbeder D and Sautereau AM (1997) Characterisation and phase behaviour of phopholipid bilayers adsorbed on spherical polysaccharidic nanoparticles. Biochim Biophy Acta 1327:32-40.
21. McCarthy KM, Skare IB, Stankewich MC, Furuse M, Tsukita S, Rogers RA, Lynch RD and Schneeberger EE (1996) Occludin is a functional component of the tight junction. J Cell Sci 109:2287-2298.
22. Mobley WC (1989) Nerve growth factor in Alzheimer's disease: To treat or not to treat? Neurobiol Aging 10:578-590.
23. Napper DH and Netchey A (1971) Studies of the steric stabilisation of colloidal particles J Colloid Interface Sci 37:528-535.
24. Olson L, Nordberg A, von Holst H, Backman L, Ebendal T, Alafuzoff I, Hartvig P, Herlitz A and Lilja A (1992) Nerve growth factor affects 11C-nicotine binding, blood flow, EEG, and verbal episodic memory in an Alzheimer patient (case report). J Neural Transm 4:79-95.
25. Pardridge WM, Eisenberg J and Cefalu WT (1985) Absence of albumin receptor on brain capillaires in vivo and in vitro. Am J Physiol 249:E264-E267.
26. + T-cell clones in vitro. Vaccine 14: 511-520.
27. Rapoport SI (1988) Osmotic opening of the blood brain barrier. Ann Neurol 24:677-684.
28. Reese TS and Karnovsky MJ (1967) Fine structure localization of a blood-brain barrier to exogenous peroxidase. J Cell Biol 34:207-217.
29. Schnitzer JE (1993) Update on the cellular and molecular basis of capillary permeability. Trends Cardiovasc Med 3:124-130.
30. Schnitzer JE, Allard J and Oh P (1995) NEM inhibits transcytosis, endocytosis, and capillary permeability: Implication of caveolae fusion in endothelia. Am J Physiol 268:H48-H55.
31. Schnitzer JE and Oh P (1994) Albondin-mediated capillary permeability to albumin: Differential role of receptors in endothelial transcytosis and endocytosis of native and modified albumins. J Biol Chem 269:6072-6082.
32. Smart EJ, Ying YS, Mineo C and Anderson RG (1995) A detergent free method for purifying caveolae membrane from tissue culture cells. Proc Natl Acad Sci USA 92:10104-10108.
33. Smith KR and Borchardt RT (1989) Permeability and mechanism of albumin and glycosylated albumin transcellular transport across across monolayers of cultured bovine brain capillary endothelial cells. Pharmacol Res 6:466-473.
34. Suhr ST and Gage FH (1993) Gene therapy for neurologic disease. Arch Neurol 50:1252-1268.
35. Tack BF, Dean J, Eilat D, Lorenz PE and Schlechter AN (1980) Tritium labeling of proteins to high specific radioactivity by reduction methylation. J Biol Chem 255:8842-8847.
36. Weiss L, Zeigel R, Jung OS and Bross ID (1972) Binding of positively charged particles to glutaraldehyde-fixed human erythrocytes. Esp Cell Res 70:57-64.
37. Woodle HC and Papahadjopoulos D (1989) Liposome preparation and size characterization. Methods Enzymol 171:193-217.