Targeting liposomes with protein drugs to the blood-brain barrier in vitro

European Journal of Pharmaceutical Sciences

Volumn 25, Issue 2-3, 2005, Pages 299-305

  Visser, Corine C ^a   Stevanović, Sanja ^a   Voorwinden, L Heleen ^a   Van Bloois, Louis ^b   Gaillard, Pieter J ^a   Danhof, Meindert ^a   Crommelin, Daan J A ^b   De Boer, Albertus G ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Blood brain barrier; Endosomes; Horseradish peroxidase; Lysosomes; Transferrin receptor

Indexed keywords

HORSERADISH PEROXIDASE; LIPOSOME; MACROGOL 2000; TRANSFERRIN;

ANIMAL CELL; ARTICLE; BLOOD BRAIN BARRIER; CAPILLARY ENDOTHELIUM; CONTROLLED STUDY; COW; DRUG DELIVERY SYSTEM; DRUG TARGETING; ENDOCYTOSIS; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME DEGRADATION; NONHUMAN; PRIORITY JOURNAL; TEMPERATURE SENSITIVITY;

ANIMALS; BLOOD-BRAIN BARRIER; CATTLE; CELLS, CULTURED; DRUG DELIVERY SYSTEMS; ENDOTHELIAL CELLS; HORSERADISH PEROXIDASE; LIPOSOMES; POLYETHYLENE GLYCOLS; PROTEINS; RECEPTORS, TRANSFERRIN; SPECTROPHOTOMETRY, ATOMIC; TRANSFERRIN;

EID: 19444367900     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2005.03.008     Document Type: Article

References (34)

1. E. Baker, and E. Morgan Iron transport J. Brock J. Halliday M. Pippard L. Powell Iron Metabolism in Health and Disease 1994 Saunders London 63 95
2. W.A. Banks, and R.D. Broadwell Blood to brain and brain to blood passage of native horseradish peroxidase, wheat germ agglutinin, and albumin: pharmacokinetic and morphological assessments J. Neurochem. 62 1994 2404 2419
3. U. Beyer, B. Rothern-Rutishauser, C. Unger, H. Wunderli-Allenspach, and F. Kratz Differences in the intracellular distribution of acid-sensitive doxorubicin-protein conjugates in comparison to free and liposomal formulated doxorubicin as shown by confocal microscopy Pharm. Res. 18 2001 29 38
4. R.D. Broadwell Transcytosis of macromolecules through the blood-brain barrier: a cell biological perspective and critical appraisal Acta Neuropathol. (Berl.) 79 1989 117 128
5. R.D. Broadwell, B.J. Baker-Cairns, P.M. Friden, C. Oliver, and J.C. Villegas Transcytosis of protein through the mammalian cerebral epithelium and endothelium. III. Receptor-mediated transcytosis through the blood-brain barrier of blood-borne transferrin and antibody against the transferrin receptor Exp. Neurol. 142 1996 47 65
6. S.D. Conner, and S.L. Schmid Regulated portals of entry into the cell Nature 422 2003 37 44
7. M.L. Corvo, J.C. Jorge, R. van't Hof, M.E. Cruz, D.J. Crommelin, and G. Storm Superoxide dismutase entrapped in long-circulating liposomes: formulation design and therapeutic activity in rat adjuvant arthritis Biochim. Biophys. Acta 1564 2002 227 236
8. D.J. Crommelin Influence of lipid composition and ionic strength on the physical stability of liposomes J. Pharm. Sci. 73 1984 1559 1563
9. C.A. Enns, and H.H. Sussman Physical characterization of the transferrin receptor in human placentae J. Biol. Chem. 256 1981 9820 9823
10. H. Fukushima, M. Iwasaki, O. Yosie, and H. Igarashi Induction of reduced endothelial permeability to horseradish peroxidase by factor(s) of human astrocytes and bladder carcinoma cells: detection in multi-well plate culture Methods Cell Sci. 23 2001 211 219
11. P.J. Gaillard, L.H. Voorwinden, J.L. Nielsen, A. Ivanov, R. Atsumi, H. Engman, C. Ringbom, A.G. de Boer, and D.D. Breimer Establishment and functional characterization of an in vitro model of the blood-brain barrier, comprising a co-culture of brain capillary endothelial cells and astrocytes Eur. J. Pharm. Sci. 12 2001 215 222
12. G. Gregoriadis Engineering liposomes for drug delivery: progress and problems Trends Biotechnol. 13 1995 527 537
13. J. Huwyler, A. Cerletti, G. Fricker, A.N. Eberle, and J. Drewe By-passing of P-glycoprotein using immunoliposomes J. Drug Target 10 2002 73 79
14. D.L. Iden, and T.M. Allen In vitro and in vivo comparison of immunoliposomes made by conventional coupling techniques with those made by a new post-insertion approach Biochim. Biophys. Acta 1513 2001 207 216
15. T. Kakudo, S. Chaki, S. Futaki, I. Nakase, K. Akaji, T. Kawakami, K. Maruyama, H. Kamiya, and H. Harashima Transferrin-modified liposomes equipped with a pH-sensitive fusogenic peptide: an artificial viral-like delivery system Biochemistry 43 19 2004 5618 5628
16. E. Mastrobattista, D.J. Crommelin, J. Wilschut, and G. Storm Targeted liposomes for delivery of protein-based drugs into the cytoplasm of tumor cells J. Liposome Res. 12 2002 57 65
17. T. Moos, and E.H. Morgan Transferrin and transferrin receptor function in brain barrier systems Cell Mol. Neurobiol. 20 2000 77 95
18. J.N. Moreira, T. Ishida, R. Gaspar, and T.M. Allen Use of the post-insertion technique to insert peptide ligands into pre-formed stealth liposomes with retention of binding activity and cytotoxicity Pharm. Res. 19 2002 265 269
19. S. Mumtaz, and B.K. Bachhawat Enhanced intracellular stability of dextran-horse radish peroxidase conjugate: an approach to enzyme replacement therapy Biochim. Biophys. Acta 1117 1992 174 178
20. G. Ojteg, K. Nygren, and M. Wolgast Permeability of renal capillaries. I. Preparation of neutral and charged protein probes Acta Physiol. Scand. 129 1987 277 286
21. W.M. Pardridge CNS drug design based on principles of blood-brain barrier transport J. Neurochem. 70 1998 1781 1792
22. W.M. Pardridge Blood-brain barrier biology and methodology J. Neurovirol. 5 1999 556 569
23. W.M. Pardridge Drug and gene delivery to the brain: the vascular route Neuron 36 2002 555 558
24. R.A. Parente, S. Nier, and F.C. Szoka Jr. Mechanism of leakage of phospholipid vesicle contents induced by the peptide GALA Biochemistry 29 37 1990 8720 8728
25. J. Rejman, V. Oberle, I.S. Zuhorn, and D. Hoekstra Size-dependent internalization of particles via the pathways of clathrin- and caveolae-mediated endocytosis Biochem. J. 377 2004 159 169
26. G. Rouser, S. Fkeischer, and A. Yamamoto Two dimensional then layer chromatographic separation of polar lipids and determination of phospholipids by phosphorus analysis of spots Lipids 5 1970 494 496
27. L.L. Rubin, and J.M. Staddon The cell biology of the blood-brain barrier Annu. Rev. Neurosci. 22 1999 11 28
28. H. Schreier, P. Moran, and I.W. Caras Targeting of liposomes to cells expressing CD4 using glycosylphosphatidylinositol-anchored gp120. Influence of liposome composition on intracellular trafficking J. Biol. Chem. 269 1994 9090 9098
29. N. Shi, R.J. Boado, and W.M. Pardridge Receptor-mediated gene targeting to tissues in vivo following intravenous administration of pegylated immunoliposomes Pharm. Res. 18 2001 1091 1095
30. R.S. Tirumalai, K.C. Chan, D.A. Prieto, H.J. Issaq, T.P. Conrads, and T.D. Veenstra Characterization of the low molecular weight human serum proteome Mol. Cell Proteomics 2 2003 1096 1103
31. M.H. Vingerhoeds, P.A. Steerenberg, J.J. Hendriks, D.J. Crommelin, and G. Storm Targeted delivery of diphtheria toxin via immunoliposomes: efficient antitumor activity in the presence of inactivating anti-diphtheria toxin antibodies FEBS Lett. 395 1996 245 250
32. C.C. Visser, L.H. Voorwinden, D.J.A. Crommelin, M. Danhof, and A.G. de Boer Characterization and modulation of the transferrin receptor on brain capillary endothelial cells Pharm. Res. 21 2004 761 769
33. C.C. Visser, S. Stevanovic, L.H. Voorwinden, P.J. Gaillard, D.J.A. Crommelin, M. Danhof, and A.G. de Boer Validation of the transferrin receptor for drug targeting to brain capillary endothelial cells in vitro J. Drug Target 12 3 2004 145 150
34. C.C. Visser, L.H. Voorwinden, E.R. Harders, M. Eloualid, L. van Bloois, D.J.A. Crommelin, M. Danhof, and A.G. de Boer Coupling of metal containing homing devices to liposomes via a maleimide linker: use of TCEP to stabilize thiol-groups without scavenging metals J. Drug Target 12 9-10 2004 948 953