Indirect evidence that drug brain targeting using polysorbate 80- coated polybutylcyanoacrylate nanoparticles is related to toxicity

Pharmaceutical Research

Volumn 16, Issue 12, 1999, Pages 1836-1842

  Olivier, Jean Christophe ^a   Fenart, Laurence ^b   Chauvet, Romain ^a   Pariat, Claudine ^a   Cecchelli, Roméo ^c   Couet, William ^a  

^a UPRES EA 1223   (France)

^b INSERM   (France)

^c Université des Sciences   (France)

Author keywords

Blood brain barrier; Brain targeting; Dalargin; Nanoparticles; Polybutylcyanoacrylate; Polystyrene

Indexed keywords

DRUG CARRIER; LEUCINE ENKEPHALIN[2 DEXTRO ALANINE]; NANOPARTICLE; POLY(BUTYL 2 CYANOACRYLATE); POLYSORBATE 80; POLYSTYRENE; UNCLASSIFIED DRUG;

ANALGESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIODEGRADATION; BLOOD BRAIN BARRIER; CATTLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BRAIN LEVEL; DRUG MECHANISM; DRUG PENETRATION; DRUG TARGETING; LOCOMOTION; MALE; MOUSE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL;

EID: 0033427851     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1018947208597     Document Type: Article

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