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Volumn 20, Issue 3, 2014, Pages 474-482

Nanotechnology versus other techniques in improving drug dissolution

Author keywords

Agglomeration; Complexation; Dissolution rate; Nanoparticles; Nanosuspension; Prodrug; Salt form; Solubility; Stability; Surface area

Indexed keywords

BIOLOGICAL AVAILABILITY; CHEMICAL PRECIPITATION; CHEMISTRY, PHARMACEUTICAL; CRYSTALLIZATION; DRUG STABILITY; MODELS, CHEMICAL; NANOPARTICLES; NANOTECHNOLOGY; PARTICLE SIZE; PHARMACEUTICAL PREPARATIONS; PLANT PREPARATIONS; SOLUBILITY; SURFACE PROPERTIES; TECHNOLOGY, PHARMACEUTICAL;

EID: 84894039187     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/13816128113199990400     Document Type: Article
Times cited : (42)

References (98)
  • 1
    • 0035997323 scopus 로고    scopus 로고
    • Biopharmaceutics classification system: The scientific basis for biowaiver extensions
    • Yu LX, Amidon GL, Polli JE, et al. Biopharmaceutics classification system: The scientific basis for biowaiver extensions. Pharm Res 2002; 19: 921-5.
    • (2002) Pharm Res , vol.19 , pp. 921-925
    • Yu, L.X.1    Amidon, G.L.2    Polli, J.E.3
  • 2
    • 84967407676 scopus 로고    scopus 로고
    • Drug nanocrystals/naosuspensions for the delivery of poorly soluble drugs
    • In: Torchilin, V. P. Ed, London, Imperial College Press
    • Müller RH, Junghanns JUAH. Drug nanocrystals/naosuspensions for the delivery of poorly soluble drugs. In: Torchilin, V. P. Ed, Nanoparticulates as Drug Carriers. London, Imperial College Press. 2006.
    • (2006) Nanoparticulates as Drug Carriers.
    • Müller, R.H.1    Junghanns, J.U.A.H.2
  • 3
    • 30444441465 scopus 로고    scopus 로고
    • The potential advantages of nanoparticle drug delivery systems in chemotherapy of tuberculosis
    • Gelperina S, Kisich K, Iseman MD, Heifets L. The potential advantages of nanoparticle drug delivery systems in chemotherapy of tuberculosis. Am J Respir Crit Care Med 2005; 172: 1487-90.
    • (2005) Am J Respir Crit Care Med , vol.172 , pp. 1487-1490
    • Gelperina, S.1    Kisich, K.2    Iseman, M.D.3    Heifets, L.4
  • 4
    • 33747373878 scopus 로고    scopus 로고
    • A century of dissolution research: From Noyes and Whitney to the Biopharmaceutics Classification System
    • Dokoumetzidis A, Macheras P. A century of dissolution research: From Noyes and Whitney to the Biopharmaceutics Classification System. Int J Pharm 2006; 321: 1-11.
    • (2006) Int J Pharm , vol.321 , pp. 1-11
    • Dokoumetzidis, A.1    McHeras, P.2
  • 6
    • 53949114467 scopus 로고    scopus 로고
    • Fundamentals of drug nanoparticles
    • In: Gupta, R. B.; Kompella, U. B. Ed, New York, NY, Taylor and Francis Group
    • Gupta RB. Fundamentals of drug nanoparticles. In: Gupta, R. B.; Kompella, U. B. Ed, Nanoparticle Technology for Drug Delivery. New York, NY, Taylor and Francis Group 2006.
    • (2006) Nanoparticle Technology for Drug Delivery.
    • Gupta, R.B.1
  • 7
    • 47949120037 scopus 로고    scopus 로고
    • Dissolution kinetic behavior of drug nanoparticles and their conformity to the diffusion model
    • Heng D, Cutler DJ, Chan HK, Yun J, Raper JA. Dissolution kinetic behavior of drug nanoparticles and their conformity to the diffusion model. Langmuir 2008; 24: 7538-44.
    • (2008) Langmuir , vol.24 , pp. 7538-7544
    • Heng, D.1    Cutler, D.J.2    Chan, H.K.3    Yun, J.4    Raper, J.A.5
  • 8
    • 83355163244 scopus 로고    scopus 로고
    • Self-assembled amorphous drugpolyelectrolyte nanoparticle complex with enhanced dissolution rate and saturation solubility
    • Cheow WS, Hadinoto K. Self-assembled amorphous drugpolyelectrolyte nanoparticle complex with enhanced dissolution rate and saturation solubility. J Colloid Interface Sci 2012; 367: 518-26.
    • (2012) J Colloid Interface Sci , vol.367 , pp. 518-526
    • Cheow, W.S.1    Hadinoto, K.2
  • 9
    • 1142303337 scopus 로고    scopus 로고
    • What is the true solubility advantage for amorphous pharmaceuticals?
    • Hancock BC, Parks M. What is the true solubility advantage for amorphous pharmaceuticals? Pharm Res 2000; 17: 397-404.
    • (2000) Pharm Res , vol.17 , pp. 397-404
    • Hancock, B.C.1    Parks, M.2
  • 10
    • 76649105411 scopus 로고    scopus 로고
    • Solubility advantage of amorphous pharmaceuticals: I. A thermodynamic analysis
    • Murdande SB, Pikal MJ, Shankar RM, Bogner RH. Solubility advantage of amorphous pharmaceuticals: I. A thermodynamic analysis. J Pharm Sci 2010; 99: 1254-64.
    • (2010) J Pharm Sci , vol.99 , pp. 1254-1264
    • Murdande, S.B.1    Pikal, M.J.2    Shankar, R.M.3    Bogner, R.H.4
  • 11
    • 78651288987 scopus 로고    scopus 로고
    • Solubility advantage of amorphous pharmaceuticals: II. Application of quantitative thermodynamic relationships for prediction of solubility enhancement in structurally diverse insoluble pharmaceuticals
    • Murdande SB, Pikal MJ, Shankar RM, Bogner RH. Solubility advantage of amorphous pharmaceuticals: II. Application of quantitative thermodynamic relationships for prediction of solubility enhancement in structurally diverse insoluble pharmaceuticals. Pharm Res 2010; 27: 2704-14.
    • (2010) Pharm Res , vol.27 , pp. 2704-2714
    • Murdande, S.B.1    Pikal, M.J.2    Shankar, R.M.3    Bogner, R.H.4
  • 12
    • 84859430848 scopus 로고    scopus 로고
    • In vitro and in vivo characterization of amorphous, nanocrystalline, and crystalline ziprasidone formulations
    • Thombre AG, Shah JC, Sagawa K, Caldwell WB. In vitro and in vivo characterization of amorphous, nanocrystalline, and crystalline ziprasidone formulations. Int J Pharm 2012; 428: 8-17.
    • (2012) Int J Pharm , vol.428 , pp. 8-17
    • Thombre, A.G.1    Shah, J.C.2    Sagawa, K.3    Caldwell, W.B.4
  • 13
    • 79957861493 scopus 로고    scopus 로고
    • Nanosizing for oral and parenteral drug delivery: A perspective on formulating poorlywater soluble compounds using wet media milling technology
    • Merisko-Liversidge E, Liversidge GG. Nanosizing for oral and parenteral drug delivery: A perspective on formulating poorlywater soluble compounds using wet media milling technology. Adv Drug Delivery Rev 2011; 63: 427-40.
    • (2011) Adv Drug Delivery Rev , vol.63 , pp. 427-440
    • Merisko-Liversidge, E.1    Liversidge, G.G.2
  • 14
    • 41949100244 scopus 로고    scopus 로고
    • Drug nanoparticles: Formulating poorly water-soluble compounds
    • Merisko-Liversidge, E, Liversidge, GG. Drug nanoparticles: Formulating poorly water-soluble compounds. Toxicol Pathol 2008; 36: 43-8.
    • (2008) Toxicol Pathol , vol.36 , pp. 43-48
    • Merisko-Liversidge, E.1    Liversidge, G.G.2
  • 15
    • 0037312695 scopus 로고    scopus 로고
    • Nanosizing: A formulation approach for poorly-water-soluble compounds
    • Merisko-Liversidge E, Liversidge GG, Cooper ER. Nanosizing: A formulation approach for poorly-water-soluble compounds. Eur J Pharm Sci 2003; 18: 113-20.
    • (2003) Eur J Pharm Sci , vol.18 , pp. 113-120
    • Merisko-Liversidge, E.1    Liversidge, G.G.2    Cooper, E.R.3
  • 16
    • 69749103682 scopus 로고    scopus 로고
    • Nanocrystal technology, drug delivery and clinical applications
    • Junghanns J-UAH, Müller RH. Nanocrystal technology, drug delivery and clinical applications. International J Nanomed 2008; 3: 295-309.
    • (2008) International J Nanomed , vol.3 , pp. 295-309
    • Junghanns, J.-U.A.H.1    Müller, R.H.2
  • 17
    • 28444461830 scopus 로고    scopus 로고
    • Drug nanocrystals of poorly soluble drugs produced by high pressure homogenisation
    • Keck CM, Müller RH. Drug nanocrystals of poorly soluble drugs produced by high pressure homogenisation. Eur J Pharm Sci 2006; 62: 3-16.
    • (2006) Eur J Pharm Sci , vol.62 , pp. 3-16
    • Keck, C.M.1    Müller, R.H.2
  • 18
    • 53049095815 scopus 로고    scopus 로고
    • Microcrystalline cellulose, a useful alternative for sucrose as a matrix former during freeze-drying of drug nanosuspensions-A case study with itraconazole
    • Van Eerdenbrugh B, Vercruysse S, Martens JA, et al. Microcrystalline cellulose, a useful alternative for sucrose as a matrix former during freeze-drying of drug nanosuspensions-A case study with itraconazole. Eur J Pharm Biopharm 2008; 70: 590-6.
    • (2008) Eur J Pharm Biopharm , vol.70 , pp. 590-596
    • Van Eerdenbrugh, B.1    Vercruysse, S.2    Martens, J.A.3
  • 19
    • 79957768993 scopus 로고    scopus 로고
    • Production methods for nanodrug particles using the bottom-up approach
    • Chan HK, Kwok PCL. Production methods for nanodrug particles using the bottom-up approach. Adv Drug Delivery Rev 2011; 63: 406-16.
    • (2011) Adv Drug Delivery Rev , vol.63 , pp. 406-416
    • Chan, H.K.1    Kwok, P.C.L.2
  • 20
    • 43649096146 scopus 로고    scopus 로고
    • A novel production method for inhalable cyclosporine A powders by confined liquid impinging jet precipitation
    • Chiou H, Chan HK, Heng D, Prud'homme RK, Raper JA. A novel production method for inhalable cyclosporine A powders by confined liquid impinging jet precipitation. J Aerosol Sci 2008; 39: 500-9.
    • (2008) J Aerosol Sci , vol.39 , pp. 500-509
    • Chiou, H.1    Chan, H.K.2    Heng, D.3    Prud'homme, R.K.4    Raper, J.A.5
  • 21
    • 33751163286 scopus 로고    scopus 로고
    • Manufacturing of nanoparticles by milling and homogenization techniques
    • In: Gupta, R. B.; Kompella, U. B. Ed, New York, NY, Taylor and Francis Group
    • Müller RH, Möschwitzer J, Bushrab FN. Manufacturing of nanoparticles by milling and homogenization techniques. In: Gupta, R. B.; Kompella, U. B. Ed, Nanoparticle Technology for Drug Delivery. New York, NY, Taylor and Francis Group 2006.
    • (2006) Nanoparticle Technology for Drug Delivery.
    • Müller, R.H.1    Möschwitzer, J.2    Bushrab, F.N.3
  • 22
    • 80054697360 scopus 로고    scopus 로고
    • Enhanced dissolution of inhalable cyclosporine nano-matrix particles with mannitol as matrix former
    • Yamasaki K, Kwok PCL, Fukushige K, Prud'homme RK, Chan HK. Enhanced dissolution of inhalable cyclosporine nano-matrix particles with mannitol as matrix former. Int J Pharm 2011; 420: 34-42.
    • (2011) Int J Pharm , vol.420 , pp. 34-42
    • Yamasaki, K.1    Kwok, P.C.L.2    Fukushige, K.3    Prud'homme, R.K.4    Chan, H.K.5
  • 23
    • 39749100131 scopus 로고    scopus 로고
    • Preparation of inhalable salbutamol sulphate using reactive high gravity controlled precipitation
    • Hu T, Chiou H, Chan HK, Chen JF, Yun J. Preparation of inhalable salbutamol sulphate using reactive high gravity controlled precipitation. J Pharm Sci 2008; 97: 944-9.
    • (2008) J Pharm Sci , vol.97 , pp. 944-949
    • Hu, T.1    Chiou, H.2    Chan, H.K.3    Chen, J.F.4    Yun, J.5
  • 24
    • 0000924219 scopus 로고    scopus 로고
    • Micromixing and macromixing effects in unsteady chemical reaction system
    • Chang PC, Mou CY, Lee DJ. Micromixing and macromixing effects in unsteady chemical reaction system. J Physical Chem A 1999; 103: 5485-9.
    • (1999) J Physical Chem A , vol.103 , pp. 5485-5489
    • Chang, P.C.1    Mou, C.Y.2    Lee, D.J.3
  • 25
    • 0348048800 scopus 로고    scopus 로고
    • Feasibility of preparing nanodrugs by high-gravity reactive precipitation
    • Chen JF, Zhou MY, Shao L, et al. Feasibility of preparing nanodrugs by high-gravity reactive precipitation. Int J Pharm 2004; 269: 267-74.
    • (2004) Int J Pharm , vol.269 , pp. 267-274
    • Chen, J.F.1    Zhou, M.Y.2    Shao, L.3
  • 26
    • 0034110573 scopus 로고    scopus 로고
    • Synthesis of nanoparticles with novel technology: High gravity reactive precipitation
    • Chen JF, Wang YH, F G, Wang XM, Zheng C. Synthesis of nanoparticles with novel technology: High gravity reactive precipitation. Ind Eng Chem Res 2000; 39: 948-54.
    • (2000) Ind Eng Chem Res , vol.39 , pp. 948-954
    • Chen, J.F.1    Wang, Y.H.F.G.2    Wang, X.M.3    Zheng, C.4
  • 27
    • 48049124105 scopus 로고    scopus 로고
    • Engineering of drug nanoparticles by HGCP for pharmaceutical applications
    • Hu TT, Wang JX, Shen ZG, Chen JF. Engineering of drug nanoparticles by HGCP for pharmaceutical applications. Particuology 2008; 6: 239-51.
    • (2008) Particuology , vol.6 , pp. 239-251
    • Hu, T.T.1    Wang, J.X.2    Shen, Z.G.3    Chen, J.F.4
  • 28
    • 38549145278 scopus 로고    scopus 로고
    • Evaluation on the use of confined liquid impinging jets fot the synthesis of nanodrug particles
    • Chiou H, Chan HK, Prud'homme RK, Raper JA. Evaluation on the use of confined liquid impinging jets fot the synthesis of nanodrug particles. Drug Development Ind Pharm 2008; 34: 59-64.
    • (2008) Drug Development Ind Pharm , vol.34 , pp. 59-64
    • Chiou, H.1    Chan, H.K.2    Prud'homme, R.K.3    Raper, J.A.4
  • 29
    • 78650390628 scopus 로고    scopus 로고
    • Fluorescent polymeric nanoparticles: Aggregation and phase behavior of pyrene and amphotericin B molecules into nanoparticle cores
    • Kumar V, Adamson DH, Prud'homme RK. Fluorescent polymeric nanoparticles: Aggregation and phase behavior of pyrene and amphotericin B molecules into nanoparticle cores. Small 2010; 6: 2907-14.
    • (2010) Small , vol.6 , pp. 2907-2914
    • Kumar, V.1    Adamson, D.H.2    Prud'homme, R.K.3
  • 30
    • 66749103287 scopus 로고    scopus 로고
    • Protected peptide nanoparticles: Experiments and brownian dynamics simulations of the energetics of assembly
    • Chen T, D'Addio SM, Kennedy MT, et al. Protected peptide nanoparticles: Experiments and brownian dynamics simulations of the energetics of assembly. Nano Letters 2009; 9: 2218-22.
    • (2009) Nano Letters , vol.9 , pp. 2218-2222
    • Chen, T.1    D'Addio, S.M.2    Kennedy, M.T.3
  • 31
    • 38349183245 scopus 로고    scopus 로고
    • Composite block copolymer stabilized nanoparticles: Simultaneous encapsulation of organic actives and inorganic nanostructures
    • Gindy ME, Panagiotopoulos AZ, Prud'homme RK. Composite block copolymer stabilized nanoparticles: Simultaneous encapsulation of organic actives and inorganic nanostructures. Langmuir 2008; 24: 83-90.
    • (2008) Langmuir , vol.24 , pp. 83-90
    • Gindy, M.E.1    Panagiotopoulos, A.Z.2    Prud'homme, R.K.3
  • 32
    • 43049174741 scopus 로고    scopus 로고
    • Mixing in a multi-inlet vortex mixer (MIVM) for flash nano-precipitation
    • Liu Y, Cheng C, Liu Y, Prud'homme RK, Fox RO. Mixing in a multi-inlet vortex mixer (MIVM) for flash nano-precipitation. Chem Eng Sci 2008; 63: 2829-42.
    • (2008) Chem Eng Sci , vol.63 , pp. 2829-2842
    • Liu, Y.1    Cheng, C.2    Liu, Y.3    Prud'homme, R.K.4    Fox, R.O.5
  • 34
    • 34548542955 scopus 로고    scopus 로고
    • Nanoparticles production by supercritical antisolvent precipitation: A general interpretation
    • Reverchon E, De Marco I, Torino E. Nanoparticles production by supercritical antisolvent precipitation: A general interpretation. J Supercritical Fluids 2007; 43: 126-38.
    • (2007) J Supercritical Fluids , vol.43 , pp. 126-138
    • Reverchon, E.1    De Marco, I.2    Torino, E.3
  • 35
    • 84904818746 scopus 로고    scopus 로고
    • Development of a novel precipitation technique for the production of highly repirable powders: The atomized rapid injection for solvent extraction process
    • In: Hutchenson, K. W.; Scurto, A. M.; Subramaniam, B. Ed, Washington DC, Am Chem Soc
    • Foster NR, Sih R. Development of a novel precipitation technique for the production of highly repirable powders: The atomized rapid injection for solvent extraction process. In: Hutchenson, K. W.; Scurto, A. M.; Subramaniam, B. Ed, Gas-Expanded Liquids and Near-Critical Media. Washington DC, Am Chem Soc 2009; pp: 309-47.
    • (2009) Gas-Expanded Liquids and Near-Critical Media. , pp. 309-347
    • Foster, N.R.1    Sih, R.2
  • 38
    • 33846089370 scopus 로고    scopus 로고
    • Preparation and characterization of amorphous cefuroxime axetil drug nanoparticles with novel technology: High-gravity antisolvent precipitation
    • Chen JF, Zhang JY, Shen Z-G, Zhong J, Yun J. Preparation and characterization of amorphous cefuroxime axetil drug nanoparticles with novel technology: High-gravity antisolvent precipitation. Ind Eng Chem Res 2006; 45: 8723-7.
    • (2006) Ind Eng Chem Res , vol.45 , pp. 8723-8727
    • Chen, J.F.1    Zhang, J.Y.2    Shen, Z.-G.3    Zhong, J.4    Yun, J.5
  • 40
    • 33846640780 scopus 로고    scopus 로고
    • Production of salbutamol sulfate for inhalation by high-gravity controlled antisolvent precipitation
    • Chiou H, Li L, Hu T, Chan HK, Chen JF, Yun J. Production of salbutamol sulfate for inhalation by high-gravity controlled antisolvent precipitation. Int J Pharm 2007; 331: 93-8.
    • (2007) Int J Pharm , vol.331 , pp. 93-98
    • Chiou, H.1    Li, L.2    Hu, T.3    Chan, H.K.4    Chen, J.F.5    Yun, J.6
  • 41
    • 36749050239 scopus 로고    scopus 로고
    • Controlled liquid antisolvent precipitation of hydrophobic pharmaceutical nanoparticles in a microchannel reactor
    • Zhao H, Wang JX, Wang QA, Chen JF, Yun J. Controlled liquid antisolvent precipitation of hydrophobic pharmaceutical nanoparticles in a microchannel reactor. Ind Eng Chem Res 2007; 46: 8229-35.
    • (2007) Ind Eng Chem Res , vol.46 , pp. 8229-8235
    • Zhao, H.1    Wang, J.X.2    Wang, Q.A.3    Chen, J.F.4    Yun, J.5
  • 42
    • 79960202513 scopus 로고    scopus 로고
    • Evaluation of the Nano Spray Dryer B-90 for pharmaceutical applications
    • Schmid K, Arpagaus C, Friess W. Evaluation of the Nano Spray Dryer B-90 for pharmaceutical applications. Pharm Development Technol 2011; 16: 287-94.
    • (2011) Pharm Development Technol , vol.16 , pp. 287-294
    • Schmid, K.1    Arpagaus, C.2    Friess, W.3
  • 43
    • 78650179651 scopus 로고    scopus 로고
    • Nano spray drying: A novel method for preparing protein nanoparticles for protein therapy
    • Lee SH, Heng D, Ng HK, Chan HK, Tan RBH. Nano spray drying: a novel method for preparing protein nanoparticles for protein therapy. Int J Pharm 2011; 403: 192-200.
    • (2011) Int J Pharm , vol.403 , pp. 192-200
    • Lee, S.H.1    Heng, D.2    Ng, H.K.3    Chan, H.K.4    Tan, R.B.H.5
  • 46
    • 0038498904 scopus 로고    scopus 로고
    • Novel method for the synthesis of inhalable multicomponent drug powders with controlled morphology and size
    • In: Dalby, R. N.; Byron, P. R.; Peart, J.; Farr, S. J. Ed, Raleigh, NC, Davis Horwood International
    • Watanabe WS, Kauppinen EI, Ahonen PP, Brown DP, Muttonen E. Novel method for the synthesis of inhalable multicomponent drug powders with controlled morphology and size. In: Dalby, R. N.; Byron, P. R.; Peart, J.; Farr, S. J. Ed, Respiratory Drug Delivery VIII. Raleigh, NC, Davis Horwood International 2002; pp 795-8.
    • (2002) Respiratory Drug Delivery VIII. , pp. 795-798
    • Watanabe, W.S.1    Kauppinen, E.I.2    Ahonen, P.P.3    Brown, D.P.4    Muttonen, E.5
  • 47
    • 0024602958 scopus 로고
    • Respirable form of crystals of cromoglycic acid
    • Chan H-K, Gonda I. Respirable form of crystals of cromoglycic acid. J Pharm Sci 1989; 78: 176-80.
    • (1989) J Pharm Sci , vol.78 , pp. 176-180
    • Chan, H.-K.1    Gonda, I.2
  • 48
    • 0024865698 scopus 로고
    • Aerodynamic properties of elongated particles of cromoglycic acid
    • Chan H-K, Gonda I. Aerodynamic properties of elongated particles of cromoglycic acid. J Aerosol Sci 1989; 20: 157-68.
    • (1989) J Aerosol Sci , vol.20 , pp. 157-168
    • Chan, H.-K.1    Gonda, I.2
  • 49
    • 0342740022 scopus 로고
    • Electrospraying of conducting liquids for monodisperse aerosol generation in the 4 nm to 1.8 μm diameter range
    • Chen D-R, Pui DYH, Kaufman SL. Electrospraying of conducting liquids for monodisperse aerosol generation in the 4 nm to 1.8 μm diameter range. J Aerosol Sci 1995; 26: 963-77.
    • (1995) J Aerosol Sci , vol.26 , pp. 963-977
    • Chen, D.-R.1    Pui, D.Y.H.2    Kaufman, S.L.3
  • 50
    • 0032101058 scopus 로고    scopus 로고
    • Production of protein nanoparticles by electrospray drying
    • Gomez A, Bingham D, de Juan L, Tang K. Production of protein nanoparticles by electrospray drying. J Aerosol Sci 1998; 29: 561-74.
    • (1998) J Aerosol Sci , vol.29 , pp. 561-574
    • Gomez, A.1    Bingham, D.2    de Juan, L.3    Tang, K.4
  • 51
    • 79957691069 scopus 로고    scopus 로고
    • Physical and chemical stability of drug nanoparticles
    • Wu L, Zhang J, Watanabe W. Physical and chemical stability of drug nanoparticles. Adv Drug Delivery Rev 2011; 63: 456-69.
    • (2011) Adv Drug Delivery Rev , vol.63 , pp. 456-469
    • Wu, L.1    Zhang, J.2    Watanabe, W.3
  • 52
    • 53949092998 scopus 로고    scopus 로고
    • Top-down production of drug nanocrystals: Nanosuspension stabilization, miniaturization and transformation into solid products
    • Van Eerdenbrugh B, Van den Mooter G, Augustijns P. Top-down production of drug nanocrystals: Nanosuspension stabilization, miniaturization and transformation into solid products. Int J Pharm 2008; 364: 64-75.
    • (2008) Int J Pharm , vol.364 , pp. 64-75
    • Van Eerdenbrugh, B.1    Van den Mooter, G.2    Augustijns, P.3
  • 53
    • 0036176196 scopus 로고    scopus 로고
    • Production and characterization of a budesonide nanosuspension for pulmonary administration
    • Jacobs C, Müller RH. Production and characterization of a budesonide nanosuspension for pulmonary administration. Pharm Res 2002; 19: 189-94.
    • (2002) Pharm Res , vol.19 , pp. 189-194
    • Jacobs, C.1    Müller, R.H.2
  • 55
    • 32244448722 scopus 로고    scopus 로고
    • Nanoparticles of poorly water-soluble drugs prepared by supercritical fluid extraction of emulsions
    • Shekunov BY, Chattopadhyay P, Seitzinger J, Huff R. Nanoparticles of poorly water-soluble drugs prepared by supercritical fluid extraction of emulsions. Pharm Res 2006; 23: 196-204.
    • (2006) Pharm Res , vol.23 , pp. 196-204
    • Shekunov, B.Y.1    Chattopadhyay, P.2    Seitzinger, J.3    Huff, R.4
  • 56
    • 34848863383 scopus 로고    scopus 로고
    • Amorphous drug nanosuspensions. 3. Particle dissolution and crystal growth
    • Lennart L, Skantze P, Skantze U, Westergren J, Olsson U. Amorphous drug nanosuspensions. 3. Particle dissolution and crystal growth. Langmuir 2007; 23: 9866-74.
    • (2007) Langmuir , vol.23 , pp. 9866-9874
    • Lennart, L.1    Skantze, P.2    Skantze, U.3    Westergren, J.4    Olsson, U.5
  • 57
    • 67349239016 scopus 로고    scopus 로고
    • Preparation of hydrocortisone nanosuspension through a bottom-up nanoprecipitation technique using microfluidic reactors
    • Ali HSM, York P, Blagden N. Preparation of hydrocortisone nanosuspension through a bottom-up nanoprecipitation technique using microfluidic reactors. Int J Pharm 2009; 375: 107-13.
    • (2009) Int J Pharm , vol.375 , pp. 107-113
    • Ali, H.S.M.1    York, P.2    Blagden, N.3
  • 58
    • 33747612594 scopus 로고    scopus 로고
    • Preparation of all-trans retinoic acid nanosuspensions using a modified precipitation method
    • Zhang X, Xia Q, Gu N. Preparation of all-trans retinoic acid nanosuspensions using a modified precipitation method. Drug Development Ind Pharm 2006; 32: 857-63.
    • (2006) Drug Development Ind Pharm , vol.32 , pp. 857-863
    • Zhang, X.1    Xia, Q.2    Gu, N.3
  • 59
    • 67349098845 scopus 로고    scopus 로고
    • Diclofenac nanosuspensions: Influence of preparation procedure and crystal form on drug dissolution behaviour
    • Lai F, Sinico C, Ennas G, Marongiu F, Marongiu G, Fadda AM. Diclofenac nanosuspensions: Influence of preparation procedure and crystal form on drug dissolution behaviour. Int J Pharm 2009; 373: 124-32.
    • (2009) Int J Pharm , vol.373 , pp. 124-132
    • Lai, F.1    Sinico, C.2    Ennas, G.3    Marongiu, F.4    Marongiu, G.5    Fadda, A.M.6
  • 60
    • 51649091116 scopus 로고    scopus 로고
    • Conversion of nanosuspensions into dry powders by spray drying: A case study
    • Chaubal MV, Popescu C. Conversion of nanosuspensions into dry powders by spray drying: A case study. Pharm Res 2008; 25: 2302-8.
    • (2008) Pharm Res , vol.25 , pp. 2302-2308
    • Chaubal, M.V.1    Popescu, C.2
  • 61
    • 48849111481 scopus 로고    scopus 로고
    • Drying crystalline drug nanosuspensions-The importance of surface hydrophobicity on dissolution behavior upon redispersion
    • Van Eerdenbrugh B, Froyen L, Van Humbeck J, Martens JA, Augustijns P, Van den Mooter G. Drying crystalline drug nanosuspensions-The importance of surface hydrophobicity on dissolution behavior upon redispersion. Eur J Pharm Sci 2008; 35: 127-35.
    • (2008) Eur J Pharm Sci , vol.35 , pp. 127-135
    • Van Eerdenbrugh, B.1    Froyen, L.2    Van Humbeck, J.3    Martens, J.A.4    Augustijns, P.5    Van den Mooter, G.6
  • 62
    • 0033015283 scopus 로고    scopus 로고
    • Novel injectable formulations of insoluble drugs
    • Pace S, Pace GW, Parikh I, Misra A. Novel injectable formulations of insoluble drugs. Pharm Technol 1999; 23: 116-34.
    • (1999) Pharm Technol , vol.23 , pp. 116-134
    • Pace, S.1    Pace, G.W.2    Parikh, I.3    Misra, A.4
  • 63
    • 34547800192 scopus 로고    scopus 로고
    • Freeze-drying of nanoparticles: Formulation, process and storage considerations
    • Abdelwahed W, Degobert G, Stainmesse S, Fessi H. Freeze-drying of nanoparticles: formulation, process and storage considerations. Adv Drug Deliv Rev 2006; 58: 1688-713.
    • (2006) Adv Drug Deliv Rev , vol.58 , pp. 1688-1713
    • Abdelwahed, W.1    Degobert, G.2    Stainmesse, S.3    Fessi, H.4
  • 64
    • 78650677959 scopus 로고    scopus 로고
    • Spray-freeze-drying production of thermally sensitive polymeric nanoparticle aggregates for inhaled drug delivery: Effect of freeze-drying adjuvants
    • Cheow WS, Ng MLL, Kho K, Hadinoto K. Spray-freeze-drying production of thermally sensitive polymeric nanoparticle aggregates for inhaled drug delivery: Effect of freeze-drying adjuvants. Int J Pharm 2011; 404: 289-300.
    • (2011) Int J Pharm , vol.404 , pp. 289-300
    • Cheow, W.S.1    Ng, M.L.L.2    Kho, K.3    Hadinoto, K.4
  • 65
    • 84894094287 scopus 로고    scopus 로고
    • A comparison between spray drying and spray freeze drying for dry powder inhaler formulation of drug-loaded lipid-polymer hybrid nanoparticles
    • IN PRESS
    • Wang Y, Kho K, Cheow WS, Hadinoto K. A comparison between spray drying and spray freeze drying for dry powder inhaler formulation of drug-loaded lipid-polymer hybrid nanoparticles. Int J Pharm IN PRESS.
    • Int J Pharm
    • Wang, Y.1    Kho, K.2    Cheow, W.S.3    Hadinoto, K.4
  • 66
    • 80052808930 scopus 로고    scopus 로고
    • Optimizing aerosolization efficiency of drypowder aggregates of thermally-sensitive polymeric nanoparticles produced by spray-freeze-drying
    • Kho K, Hadinoto K. Optimizing aerosolization efficiency of drypowder aggregates of thermally-sensitive polymeric nanoparticles produced by spray-freeze-drying. Powder Technol 2011; 214: 169-76.
    • (2011) Powder Technol , vol.214 , pp. 169-176
    • Kho, K.1    Hadinoto, K.2
  • 67
    • 54349125120 scopus 로고    scopus 로고
    • Production and in vitro characterization of solid dosage form incorporating drug nanoparticles
    • Basa S, Muniyappan T, Karatgi P, Prabhu R, Pillai R. Production and in vitro characterization of solid dosage form incorporating drug nanoparticles. Drug Development Ind Pharm 2008; 34: 1209-18.
    • (2008) Drug Development Ind Pharm , vol.34 , pp. 1209-1218
    • Basa, S.1    Muniyappan, T.2    Karatgi, P.3    Prabhu, R.4    Pillai, R.5
  • 68
    • 44749092337 scopus 로고    scopus 로고
    • What is a suitable dissolution method for drug nanoparticles?
    • Heng D, Cutler DJ, Chan HK, Yun J, Raper JA. What is a suitable dissolution method for drug nanoparticles? Pharm Res 2008; 25: 1696-701.
    • (2008) Pharm Res , vol.25 , pp. 1696-1701
    • Heng, D.1    Cutler, D.J.2    Chan, H.K.3    Yun, J.4    Raper, J.A.5
  • 69
    • 53849109902 scopus 로고    scopus 로고
    • Alternative matrix formers for nanosuspension solidification: Dissolution performance and X-ray microanalysis as an evaluation tool for powder dispersion
    • Van Eerdenbrugh B, Froyen L, Van Humbeck J, Martens JA, Augustijns P, Van Den Mooter G. Alternative matrix formers for nanosuspension solidification: Dissolution performance and X-ray microanalysis as an evaluation tool for powder dispersion. Eur J Pharm Sci 2008; 35: 344-53.
    • (2008) Eur J Pharm Sci , vol.35 , pp. 344-353
    • Van Eerdenbrugh, B.1    Froyen, L.2    Van Humbeck, J.3    Martens, J.A.4    Augustijns, P.5    Van Den Mooter, G.6
  • 71
    • 34249039982 scopus 로고    scopus 로고
    • Characterization of physico-chemical properties and pharmaceutical performance of sucrose co-freeze-dried solid nanoparticulate powders of the anti-HIV agent loviride prepared by media milling
    • Van Eerdenbrugh B, Froyen L, Martens JA, et al. Characterization of physico-chemical properties and pharmaceutical performance of sucrose co-freeze-dried solid nanoparticulate powders of the anti-HIV agent loviride prepared by media milling. Int J Pharm 2007; 338: 198-206.
    • (2007) Int J Pharm , vol.338 , pp. 198-206
    • Van Eerdenbrugh, B.1    Froyen, L.2    Martens, J.A.3
  • 72
    • 71949100447 scopus 로고    scopus 로고
    • Formulation, characterization and evaluation of curcumin-loaded PLGA nanospheres for cancer therapy
    • Mukerjee A, Vishwanatha JK. Formulation, characterization and evaluation of curcumin-loaded PLGA nanospheres for cancer therapy. Anticancer Res 2009; 29: 3867-76.
    • (2009) Anticancer Res , vol.29 , pp. 3867-3876
    • Mukerjee, A.1    Vishwanatha, J.K.2
  • 73
    • 77953625233 scopus 로고    scopus 로고
    • Curcumin nanoparticles improve the physicochemical properties of curcumin and effectively enhances its antioxidant and antihepatoma activities
    • Yen FL, Wu TH, Tzeng CW, Lin LT, Lin CC. Curcumin nanoparticles improve the physicochemical properties of curcumin and effectively enhances its antioxidant and antihepatoma activities. J Agricultural Food Chem 2010; 58: 7376-82.
    • (2010) J Agricultural Food Chem , vol.58 , pp. 7376-7382
    • Yen, F.L.1    Wu, T.H.2    Tzeng, C.W.3    Lin, L.T.4    Lin, C.C.5
  • 74
  • 75
    • 42049121123 scopus 로고    scopus 로고
    • Hydrophobically modified glycol chitosan nanoparticles-encapsulated camptothecin enhance the drug stability and tumor targeting in cancer therapy
    • Min KH, Park K, Kim YS, et al. Hydrophobically modified glycol chitosan nanoparticles-encapsulated camptothecin enhance the drug stability and tumor targeting in cancer therapy. J Controlled Release 2008; 127: 208-18.
    • (2008) J Controlled Release , vol.127 , pp. 208-218
    • Min, K.H.1    Park, K.2    Kim, Y.S.3
  • 76
    • 79959430255 scopus 로고    scopus 로고
    • Berberine Alkaloid with wide spectrum of pharmacological activities
    • Singh A, Duggal S, Kaur N, Singh J. Berberine Alkaloid with wide spectrum of pharmacological activities. J Natural Products 2010; 3: 64-75.
    • (2010) J Natural Products , vol.3 , pp. 64-75
    • Singh, A.1    Duggal, S.2    Kaur, N.3    Singh, J.4
  • 77
    • 50249132924 scopus 로고    scopus 로고
    • Preparation and release characteristics of berberine chitosan nanoparticles in vitro
    • Lin A, Li H, Liu Y, Qiu X. Preparation and release characteristics of berberine chitosan nanoparticles in vitro. China Pharmacy 2007; 18: 755-7.
    • (2007) China Pharmacy , vol.18 , pp. 755-757
    • Lin, A.1    Li, H.2    Liu, Y.3    Qiu, X.4
  • 78
    • 0011155565 scopus 로고
    • Influence of formulation on dissolution rate
    • In: Leeson, L. J.; Carstensen JT. Ed, Washington DC, The Industrial Pharmaceutical Technology Section of the Academy of Pharmaceutical Science
    • Finholt P. Influence of formulation on dissolution rate. In: Leeson, L. J.; Carstensen JT. Ed, Dissolution Technology. Washington DC, The Industrial Pharmaceutical Technology Section of the Academy of Pharmaceutical Science 1974; pp 106-46.
    • (1974) Dissolution Technology. , pp. 106-146
    • Finholt, P.1
  • 79
    • 0004206781 scopus 로고    scopus 로고
    • The Stationary Office: London
    • British Pharmacopoeia, The Stationary Office: London, 2012.
    • (2012) British Pharmacopoeia
  • 80
    • 84894047346 scopus 로고    scopus 로고
    • United States Pharmacopeia 32, Rockville, MD
    • United States Pharmacopeia 32, United States Pharmacopeial Convention: Rockville, MD 2009.
    • (2009) United States Pharmacopeial Convention
  • 81
    • 0025666589 scopus 로고
    • Special cases of dissolution testing using the flow-through system
    • Moller H, Wirbitzki E. Special cases of dissolution testing using the flow-through system. STP Pharma Sci 1990; 6: 657-62.
    • (1990) STP Pharma Sci , vol.6 , pp. 657-662
    • Moller, H.1    Wirbitzki, E.2
  • 82
    • 0000995560 scopus 로고
    • Standardized flow-through method as an alternative to existing pharmacopoeial dissolution testing
    • Langenbucher F, Benz D, Kurth W, Moller H, Otz M. Standardized flow-through method as an alternative to existing pharmacopoeial dissolution testing. Pharmazeutische Industrie 1989; 51: 1276-81.
    • (1989) Pharmazeutische Industrie , vol.51 , pp. 1276-1281
    • Langenbucher, F.1    Benz, D.2    Kurth, W.3    Moller, H.4    Otz, M.5
  • 83
    • 0024315727 scopus 로고
    • A collaborative in vitro dissolution study: Comparing the flow-through method with the USP paddle method using USP prednisone calibrator tablets
    • Wennergren B, Lindberg J, Nicklasson M, et al. A collaborative in vitro dissolution study: Comparing the flow-through method with the USP paddle method using USP prednisone calibrator tablets. Int J Pharm 1989; 53: 35-41.
    • (1989) Int J Pharm , vol.53 , pp. 35-41
    • Wennergren, B.1    Lindberg, J.2    Nicklasson, M.3
  • 84
    • 0025963891 scopus 로고
    • A collaborative study of the in vitro dissolution of phenacetin crystals comparing the flow through method with the USP paddle method
    • Nicklasson M, Orbe A, Lindberg J, et al. A collaborative study of the in vitro dissolution of phenacetin crystals comparing the flow through method with the USP paddle method. International J Pharmaceutics 1991; 69: 255-64.
    • (1991) International J Pharmaceutics , vol.69 , pp. 255-264
    • Nicklasson, M.1    Orbe, A.2    Lindberg, J.3
  • 85
    • 0021829424 scopus 로고
    • Oral cefuroxime axetil: Clinical pharmacology and comparative dose studies in urinary tract infection
    • Adams DH, Wood MJ, Farrell ID. Oral cefuroxime axetil: clinical pharmacology and comparative dose studies in urinary tract infection. J Antimicrobial Chemotherapy 1985; 16: 359-66.
    • (1985) J Antimicrobial Chemotherapy , vol.16 , pp. 359-366
    • Adams, D.H.1    Wood, M.J.2    Farrell, I.D.3
  • 86
    • 78649710378 scopus 로고    scopus 로고
    • Dissolution testing of poorly soluble drugs: A continuing perspective
    • Gowthamarajan K, Singh SK. Dissolution testing of poorly soluble drugs: A continuing perspective. Dissolution Technol 2010; 17: 24-32.
    • (2010) Dissolution Technol , vol.17 , pp. 24-32
    • Gowthamarajan, K.1    Singh, S.K.2
  • 88
    • 77955086347 scopus 로고    scopus 로고
    • Pure drug nanoparticles in tablets: What are the dissolution limitations?
    • Heng D, Ogawa K, Cutler DJ, et al. Pure drug nanoparticles in tablets: What are the dissolution limitations? J Nanoparticle Res 2010; 12: 1743-54.
    • (2010) J Nanoparticle Res , vol.12 , pp. 1743-1754
    • Heng, D.1    Ogawa, K.2    Cutler, D.J.3
  • 89
    • 84894105420 scopus 로고    scopus 로고
    • Pharmaceutical salts
    • In: Liu, R. Ed, Boca Raton, FL, CRC Press
    • Neau SH. Pharmaceutical salts. In: Liu, R. Ed, Water-Insoluble Drug Formulation. Boca Raton, FL, CRC Press. 2008.
    • (2008) Water-Insoluble Drug Formulation.
    • Neau, S.H.1
  • 91
    • 0028219710 scopus 로고
    • An integrated approach to the selection of optimal salt form for a new drug candidate
    • Morris KR, Fakes MG, Thakur AB, et al. An integrated approach to the selection of optimal salt form for a new drug candidate. Int J Pharm 1994; 105: 209-17.
    • (1994) Int J Pharm , vol.105 , pp. 209-217
    • Morris, K.R.1    Fakes, M.G.2    Thakur, A.B.3
  • 92
    • 34548024418 scopus 로고    scopus 로고
    • Prodrug strategies to overcome poor water solubility
    • Stella VJ, Nti-Addae KW. Prodrug strategies to overcome poor water solubility. Adv Drug Delivery Rev 2007; 59: 677-94.
    • (2007) Adv Drug Delivery Rev , vol.59 , pp. 677-694
    • Stella, V.J.1    Nti-Addae, K.W.2
  • 93
    • 0027199124 scopus 로고
    • Phenytoin-lipid conjugates: Chemical, plasma esterase-mediated, and pancreatic lipase-mediated hydrolysis in vitro
    • Scriba GKE. Phenytoin-lipid conjugates: Chemical, plasma esterase-mediated, and pancreatic lipase-mediated hydrolysis in vitro. Pharm Res 1993; 10: 1181-6.
    • (1993) Pharm Res , vol.10 , pp. 1181-1186
    • Scriba, G.K.E.1
  • 94
    • 85123271827 scopus 로고    scopus 로고
    • Prodrugs for improved aqueous solubility
    • In: Liu, R. Ed, Boca Raton, FL, CRC Press
    • Neau SH. Prodrugs for improved aqueous solubility. In: Liu, R. Ed, Water-Insoluble Drug Formulation. Boca Raton, FL, CRC Press. 2008.
    • (2008) Water-Insoluble Drug Formulation.
    • Neau, S.H.1
  • 97
    • 85123271651 scopus 로고    scopus 로고
    • Applications of complexation in the formulation of insoluble compounds
    • In: Liu, R. Ed, Boca Raton, FL, CRC Press
    • Tong WQ, Wen H. Applications of complexation in the formulation of insoluble compounds. In: Liu, R. Ed, Water-Insoluble Drug Formulation. Boca Raton, FL, CRC Press 2008.
    • (2008) Water-Insoluble Drug Formulation.
    • Tong, W.Q.1    Wen, H.2
  • 98
    • 0141540761 scopus 로고    scopus 로고
    • Next Gereration Pharmaceutical Impactor (A new impactor for pharmaceutical inhaler testing). Part I: Design
    • Marple VA, Roberts DL, Romay FJ, et al. Next Gereration Pharmaceutical Impactor (A new impactor for pharmaceutical inhaler testing). Part I: Design. J Aerosol Med 2003; 16: 283-99.
    • (2003) J Aerosol Med , vol.16 , pp. 283-299
    • Marple, V.A.1    Roberts, D.L.2    Romay, F.J.3


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