-
1
-
-
0033977086
-
Amyloid fibrillogenesis: Themes and variations
-
Rochet JC, Lansbury PT. Amyloid fibrillogenesis: themes and variations. Curr Opin Struct Biol 2000; 10: 60-68.
-
(2000)
Curr Opin Struct Biol
, vol.10
, pp. 60-68
-
-
Rochet, J.C.1
Lansbury, P.T.2
-
2
-
-
0842281551
-
Principles of protein folding, misfolding and aggregation
-
Dobson CM. Principles of protein folding, misfolding and aggregation. Seminars Cell Developmental Biol 2004; 15: 3-16.
-
(2004)
Seminars Cell Developmental Biol
, vol.15
, pp. 3-16
-
-
Dobson, C.M.1
-
3
-
-
33746377894
-
Protein misfolding, functional amyloid, and human disease
-
Chiti F, Dobson CM. Protein misfolding, functional amyloid, and human disease. Annu Rev Biochem 2006; 75: 333-66.
-
(2006)
Annu Rev Biochem
, vol.75
, pp. 333-366
-
-
Chiti, F.1
Dobson, C.M.2
-
4
-
-
0033200063
-
Protein misfolding, evolution and disease
-
Dobson CM. Protein misfolding, evolution and disease. Trends Biochemical Sci 1999; 24: 329-32.
-
(1999)
Trends Biochemical Sci
, vol.24
, pp. 329-332
-
-
Dobson, C.M.1
-
6
-
-
0042847751
-
Cryo-electron microscopy structure of an SH3 amyloid fibril and model of the molecular packing
-
Jimenez JL, Guijarro JI, Orlova E, et al. Cryo-electron microscopy structure of an SH3 amyloid fibril and model of the molecular packing. EMBO J 1999; 18: 815-21.
-
(1999)
EMBO J
, vol.18
, pp. 815-821
-
-
Jimenez, J.L.1
Guijarro, J.I.2
Orlova, E.3
-
7
-
-
34249290108
-
Atomic structures of amyloid cross-[beta] spines reveal varied steric zippers
-
Sawaya MR, Sambashivan S, Nelson R, et al. Atomic structures of amyloid cross-[beta] spines reveal varied steric zippers. Nature 2007; 447: 453-457.
-
(2007)
Nature
, vol.447
, pp. 453-457
-
-
Sawaya, M.R.1
Sambashivan, S.2
Nelson, R.3
-
8
-
-
0033776959
-
Solid-state NMR as a probe of amyloid fibril structure
-
Tycko R. Solid-state NMR as a probe of amyloid fibril structure. Curr Opin Chem Biol 2000; 4: 500-6.
-
(2000)
Curr Opin Chem Biol
, vol.4
, pp. 500-506
-
-
Tycko, R.1
-
9
-
-
3843148352
-
Prefibrillar amyloid protein aggregates share common features of cytotoxicity
-
Bucciantini M, Calloni G, Chiti F, et al. Prefibrillar amyloid protein aggregates share common features of cytotoxicity. J Biol Chem 2004; 279: 31374-82.
-
(2004)
J Biol Chem
, vol.279
, pp. 31374-31382
-
-
Bucciantini, M.1
Calloni, G.2
Chiti, F.3
-
10
-
-
33645521792
-
Protein aggregation and its consequences for human disease
-
Dobson CM. Protein aggregation and its consequences for human disease. Protein Peptide Letters 2006; 13: 219-27.
-
(2006)
Protein Peptide Letters
, vol.13
, pp. 219-227
-
-
Dobson, C.M.1
-
11
-
-
0242668337
-
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
-
Kayed R, Head E, Thompson JL, et al. Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science 2003; 300: 486-9.
-
(2003)
Science
, vol.300
, pp. 486-489
-
-
Kayed, R.1
Head, E.2
Thompson, J.L.3
-
12
-
-
33748688511
-
Protein denaturation and aggregation. cellular responses to denatured and aggregated proteins
-
Meredith SC. Protein denaturation and aggregation. cellular responses to denatured and aggregated proteins. Ann New York Acad. Sci 2006; 1066: 181-221.
-
(2006)
Ann New York Acad. Sci
, vol.1066
, pp. 181-221
-
-
Meredith, S.C.1
-
13
-
-
77955312210
-
Amyloidogenic protein-membrane interactions: Mechanistic insight from model systems
-
Butterfield SM, Lashuel HA. Amyloidogenic protein-membrane interactions: mechanistic insight from model systems. Angew. Chem Int Ed 2010; 49: 5628-54.
-
(2010)
Angew. Chem Int Ed
, vol.49
, pp. 5628-5654
-
-
Butterfield, S.M.1
Lashuel, H.A.2
-
14
-
-
78049290389
-
Biochemical and biophysical features of both oligomer/fibril and cell membrane in amyloid cytotoxicity
-
Stefani M. Biochemical and biophysical features of both oligomer/fibril and cell membrane in amyloid cytotoxicity. FEBS J 2010; 277: 4602-13.
-
(2010)
FEBS J
, vol.277
, pp. 4602-4613
-
-
Stefani, M.1
-
15
-
-
38949167084
-
New structures help the modeling of toxic amyloid-[beta] ion channels
-
Jang H, Zheng J, Lal R, Nussinov R. New structures help the modeling of toxic amyloid-[beta] ion channels. Trends Biochem Sci 2008; 33: 91-100.
-
(2008)
Trends Biochem Sci
, vol.33
, pp. 91-100
-
-
Jang, H.1
Zheng, J.2
Lal, R.3
Nussinov, R.4
-
16
-
-
77749308402
-
Amyloid oligomers: Formation and toxicity of Aβ oligomers
-
Sakono M, Zako T. Amyloid oligomers: formation and toxicity of A[1] oligomers. FEBS J 2010; 277: 1348-58.
-
(2010)
FEBS J
, vol.277
, pp. 1348-1358
-
-
Sakono, M.1
Zako, T.2
-
17
-
-
0038778549
-
Evidence for membrane thinning effect as the mechanism for peptide-induced pore formation
-
Chen F-Y, Lee M-T, Huang HW. Evidence for membrane thinning effect as the mechanism for peptide-induced pore formation. Biophys J 2003; 84: 3751-8.
-
(2003)
Biophys J
, vol.84
, pp. 3751-3758
-
-
Chen, F.-Y.1
Lee, M.-T.2
Huang, H.W.3
-
18
-
-
23044449398
-
Amyloid ion channels: A common structural link for protein-misfolding disease
-
Quist A, Doudevski I, Lin H, et al. Amyloid ion channels: A common structural link for protein-misfolding disease. PNAS 2005; 102: 10427-32.
-
(2005)
PNAS
, vol.102
, pp. 10427-10432
-
-
Quist, A.1
Doudevski, I.2
Lin, H.3
-
19
-
-
0035927426
-
Secretase targets for Alzheimer's disease:β identification and therapeutic potential
-
Wolfe MS. Secretase targets for Alzheimer's disease:[1] identification and therapeutic potential. J Med Chem 2001; 44: 2039-60.
-
(2001)
J Med Chem
, vol.44
, pp. 2039-2060
-
-
Wolfe, M.S.1
-
20
-
-
79851473226
-
γ-secretase modulators as potential disease modifying anti-Alzheimer's drugs
-
Oehlrich D, Berthelot DJC, Gijsen HJM. γ-secretase modulators as potential disease modifying anti-Alzheimer's drugs. J Med Chem 2010; 54: 669-98.
-
(2010)
J Med Chem
, vol.54
, pp. 669-698
-
-
Oehlrich, D.1
Berthelot, D.J.C.2
Gijsen, H.J.M.3
-
21
-
-
57349107392
-
Peptide and protein mimetics inhibiting amyloid β-peptide aggregation
-
Takahashi T, Mihara H. Peptide and protein mimetics inhibiting amyloid-peptide aggregation. Acc Chem Res 2008; 41: 1309-18.
-
(2008)
Acc Chem Res
, vol.41
, pp. 1309-1318
-
-
Takahashi, T.1
Mihara, H.2
-
22
-
-
33746649088
-
Anti-amyloidogenic therapies: Strategies for prevention and treatment of Alzheimer's disease
-
Hamaguchi T, Ono K, Yamada M. Anti-amyloidogenic therapies: strategies for prevention and treatment of Alzheimer's disease. Cellular Mol Life Sci 2006; 63: 1538-52.
-
(2006)
Cellular Mol Life Sci
, vol.63
, pp. 1538-1552
-
-
Hamaguchi, T.1
Ono, K.2
Yamada, M.3
-
23
-
-
77958065164
-
Combination of kinetically selected inhibitors in trans leads to highly effective inhibition of amyloid formation
-
Meng F, Raleigh DP, Abedini A. Combination of kinetically selected inhibitors in trans leads to highly effective inhibition of amyloid formation. J Am Chem Soc 2010; 132: 14340-2.
-
(2010)
J Am Chem Soc
, vol.132
, pp. 14340-14342
-
-
Meng, F.1
Raleigh, D.P.2
Abedini, A.3
-
24
-
-
0141741347
-
Parkinson's disease: Mechanisms and models
-
Dauer W, Przedborski S. Parkinson's disease: mechanisms and models. Neuron 2003; 39: 889-909.
-
(2003)
Neuron
, vol.39
, pp. 889-909
-
-
Dauer, W.1
Przedborski, S.2
-
25
-
-
0032150877
-
Genetic dissection of Alzheimer's disease and related dementias: Amyloid and its relationship to tau
-
Hardy J, Duff K, Gwinn Hardy K, Perez-Tur J, Hutton M. Genetic dissection of Alzheimer's disease and related dementias: amyloid and its relationship to tau. Nature Neurosci 1998; 1: 355-8.
-
(1998)
Nature Neurosci
, vol.1
, pp. 355-358
-
-
Hardy, J.1
Duff, K.2
Gwinn Hardy, K.3
Perez-Tur, J.4
Hutton, M.5
-
26
-
-
67650809307
-
Functional amyloids as natural storage of peptide hormones in pituitary secretory granules
-
Maji SK, Perrin MH, Sawaya MR, et al. Functional amyloids as natural storage of peptide hormones in pituitary secretory granules. Science 2009; 325: 328-32.
-
(2009)
Science
, vol.325
, pp. 328-332
-
-
Maji, S.K.1
Perrin, M.H.2
Sawaya, M.R.3
-
27
-
-
58149147452
-
Ultra-sensitive immunosensor for [beta]-amyloid (1-42) using scanning tunneling microscopybased electrical detection
-
Kang DY, Lee JH, Oh BK, Choi JW. Ultra-sensitive immunosensor for [beta]-amyloid (1-42) using scanning tunneling microscopybased electrical detection. Biosensors and Bioelectronics 2009; 24: 1431-6.
-
(2009)
Biosensors and Bioelectronics
, vol.24
, pp. 1431-1436
-
-
Kang, D.Y.1
Lee, J.H.2
Oh, B.K.3
Choi, J.W.4
-
28
-
-
79955681481
-
Biomarkers of Alzheimer's disease in the cerebrospinal fluid of spanish patients with mild cognitive impairment
-
Monge-Argilés J, Muñoz-Ruiz C, Pampliega-Pérez A, et al. Biomarkers of Alzheimer's disease in the cerebrospinal fluid of spanish patients with mild cognitive impairment. Neurochemical Res 2011; 36: 986-93.
-
(2011)
Neurochemical Res
, vol.36
, pp. 986-993
-
-
Monge-Argilés, J.1
Muñoz-Ruiz, C.2
Pampliega-Pérez, A.3
-
29
-
-
0036975682
-
β-amyloid production, aggregation, and clearance as targets for therapy in Alzheimer's disease
-
De Felice FG, Ferreira ST. β-amyloid production, aggregation, and clearance as targets for therapy in Alzheimer's disease. Cellular Mol Neurobiol 2002; 22: 545-63.
-
(2002)
Cellular Mol Neurobiol
, vol.22
, pp. 545-563
-
-
de Felice, F.G.1
Ferreira, S.T.2
-
30
-
-
27744439131
-
Blockade of [gamma]-secretase activity within the hippocampus enhances long-term memory
-
Dash PK, Moore AN, Orsi SA. Blockade of [gamma]-secretase activity within the hippocampus enhances long-term memory. Biochem Biophys Res Commun 2005; 338: 777-82.
-
(2005)
Biochem Biophys Res Commun
, vol.338
, pp. 777-782
-
-
Dash, P.K.1
Moore, A.N.2
Orsi, S.A.3
-
31
-
-
33644878338
-
The novel beta-secretase inhibitor KMI-429 reduces amyloid beta peptide production in amyloid precursor protein transgenic and wild-type mice
-
Asai M, Hattori C, Iwata N, et al. The novel beta-secretase inhibitor KMI-429 reduces amyloid beta peptide production in amyloid precursor protein transgenic and wild-type mice. J Neurochem 2006; 96: 533-40.
-
(2006)
J Neurochem
, vol.96
, pp. 533-540
-
-
Asai, M.1
Hattori, C.2
Iwata, N.3
-
32
-
-
0035106780
-
Imaging of amyloid-[beta] deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy
-
Bacskai BJ, Kajdasz ST, Christie RH, et al. Imaging of amyloid-[beta] deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy. Nat Med 2001; 7: 369-72.
-
(2001)
Nat Med
, vol.7
, pp. 369-372
-
-
Bacskai, B.J.1
Kajdasz, S.T.2
Christie, R.H.3
-
33
-
-
77952138141
-
Strategies for the Inhibition of Protein Aggregation in Human Diseases
-
Bartolini M, Andrisano V. Strategies for the Inhibition of Protein Aggregation in Human Diseases. ChemBioChem 2010; 11: 1018-35.
-
(2010)
ChemBioChem
, vol.11
, pp. 1018-1035
-
-
Bartolini, M.1
Andrisano, V.2
-
34
-
-
0141642253
-
Potent anti-amyloidogenic and fibril-destabilizing effects of polyphenols in vitro: Implications for the prevention and therapeutics of Alzheimer's disease
-
Ono K, Yoshiike Y, Takashima A, Hasegawa K, Naiki H, Yamada M. Potent anti-amyloidogenic and fibril-destabilizing effects of polyphenols in vitro: implications for the prevention and therapeutics of Alzheimer's disease. J Neurochem 2003; 87: 172-81.
-
(2003)
J Neurochem
, vol.87
, pp. 172-181
-
-
Ono, K.1
Yoshiike, Y.2
Takashima, A.3
Hasegawa, K.4
Naiki, H.5
Yamada, M.6
-
35
-
-
67650844215
-
Comparative study of inhibition at multiple stages of amyloid-beta self-assembly provides mechanistic insight
-
Davis TJ, Soto-Ortega DD, Kotarek JA, et al. Comparative study of inhibition at multiple stages of amyloid-beta self-assembly provides mechanistic insight. Mol Pharmacol 2009; 76: 405-13.
-
(2009)
Mol Pharmacol
, vol.76
, pp. 405-413
-
-
Davis, T.J.1
Soto-Ortega, D.D.2
Kotarek, J.A.3
-
36
-
-
0034718206
-
Approaches to discovery and characterization of inhibitors of amyloid β-peptide polymerization
-
Findeis MA. Approaches to discovery and characterization of inhibitors of amyloid-peptide polymerization. BBA-Molecular Basis of Disease 2000; 1502: 76-84.
-
(2000)
BBA-Molecular Basis of Disease
, vol.1502
, pp. 76-84
-
-
Findeis, M.A.1
-
37
-
-
34249860495
-
Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct
-
Necula M, Kayed R, Milton S, Glabe CG. Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct. J Biol Chem 2007; 282: 10311-24.
-
(2007)
J Biol Chem
, vol.282
, pp. 10311-10324
-
-
Necula, M.1
Kayed, R.2
Milton, S.3
Glabe, C.G.4
-
38
-
-
39349094523
-
Small-molecule aggregates inhibit amyloid polymerization
-
Feng BY, Toyama BH, Wille H, et al. Small-molecule aggregates inhibit amyloid polymerization. Nat Chem Biol 2008; 4: 197-9.
-
(2008)
Nat Chem Biol
, vol.4
, pp. 197-199
-
-
Feng, B.Y.1
Toyama, B.H.2
Wille, H.3
-
39
-
-
84856873078
-
Hydrophobicity and conformational change as mechanistic determinants for nonspecific modulators of amyloid-β selfassembly
-
Abelein A, Bolognesi B, Dobson CM, Gräslund A, Lendel C. Hydrophobicity and conformational change as mechanistic determinants for nonspecific modulators of amyloid-β selfassembly. Biochemistry 2011; 51: 126-37.
-
(2011)
Biochemistry
, vol.51
, pp. 126-137
-
-
Abelein, A.1
Bolognesi, B.2
Dobson, C.M.3
Gräslund, A.4
Lendel, C.5
-
40
-
-
37349075778
-
Congo red and thioflavin-T analogs detect Aβ oligomers
-
Maezawa I, Hong HS, Liu R, et al. Congo red and thioflavin-T analogs detect A oligomers. J Neurochem 2008; 104: 457-68.
-
(2008)
J Neurochem
, vol.104
, pp. 457-468
-
-
Maezawa, I.1
Hong, H.S.2
Liu, R.3
-
41
-
-
44849087785
-
EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers
-
Ehrnhoefer DE, Bieschke J, Boeddrich A, et al. EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers. Nature Struct Mol Biol 2008; 15: 558-66.
-
(2008)
Nature Struct Mol Biol
, vol.15
, pp. 558-566
-
-
Ehrnhoefer, D.E.1
Bieschke, J.2
Boeddrich, A.3
-
42
-
-
41949119161
-
Ibuprofen reduces A[beta], hyperphosphorylated tau and memory deficits in Alzheimer mice
-
McKee AC, Carreras I, Hossain L, et al. Ibuprofen reduces A[beta], hyperphosphorylated tau and memory deficits in Alzheimer mice. Brain Res 2008; 1207: 225-36.
-
(2008)
Brain Res
, vol.1207
, pp. 225-236
-
-
McKee, A.C.1
Carreras, I.2
Hossain, L.3
-
43
-
-
77953060906
-
Ibuprofen modifies cognitive disease progression in an Alzheimer's mouse model
-
0269881108097630
-
Van Dam D, Coen K, De Deyn PP. Ibuprofen modifies cognitive disease progression in an Alzheimer's mouse model. J Psychopharmacol 2008: 0269881108097630.
-
(2008)
J Psychopharmacol
-
-
van Dam, D.1
Coen, K.2
de Deyn, P.P.3
-
44
-
-
20044370990
-
Curcumin inhibits formation of amyloid β oligomers and fibrils, binds plaques, and reduces amyloid in vivo
-
Yang F, Lim GP, Begum AN, et al. Curcumin inhibits formation of amyloid oligomers and fibrils, binds plaques, and reduces amyloid in vivo. J Biol Chem 2005; 280: 5892-901.
-
(2005)
J Biol Chem
, vol.280
, pp. 5892-5901
-
-
Yang, F.1
Lim, G.P.2
Begum, A.N.3
-
45
-
-
10744224267
-
Metal-protein attenuation with Iodochlorhydroxyquin (Clioquinol) targeting A{beta} amyloid deposition and toxicity in Alzheimer disease: A pilot phase 2 clinical trial
-
Ritchie CW, Bush AI, Mackinnon A, et al. Metal-protein attenuation with Iodochlorhydroxyquin (Clioquinol) targeting A{beta} amyloid deposition and toxicity in Alzheimer disease: A pilot phase 2 clinical trial. Arch Neurol 2003; 60: 1685-91.
-
(2003)
Arch Neurol
, vol.60
, pp. 1685-1691
-
-
Ritchie, C.W.1
Bush, A.I.2
Mackinnon, A.3
-
46
-
-
73149091019
-
A peptide hairpin inhibitor of amyloid beta-protein oligomerization and fibrillogenesis
-
Yamin G, Ruchala P, Teplow DB. A peptide hairpin inhibitor of amyloid beta-protein oligomerization and fibrillogenesis. Biochemistry 2009; 48: 11329-31.
-
(2009)
Biochemistry
, vol.48
, pp. 11329-11331
-
-
Yamin, G.1
Ruchala, P.2
Teplow, D.B.3
-
47
-
-
36049022567
-
New insights into the mechanism of alzheimer amyloid-{beta} fibrillogenesis inhibition by n-Methylated peptides
-
Soto P, Griffin MA, Shea JE. New insights into the mechanism of alzheimer amyloid-{beta} fibrillogenesis inhibition by n-Methylated peptides. Biophys J 2007; 93: 3015-25.
-
(2007)
Biophys J
, vol.93
, pp. 3015-3025
-
-
Soto, P.1
Griffin, M.A.2
Shea, J.E.3
-
48
-
-
33747113591
-
Spatial separation of [beta]-sheet domains of [beta]-amyloid: Disruption of each [beta]-sheet by N-methyl amino acids
-
Sciarretta KL, Boire A, Gordon DJ, Meredith SC. Spatial separation of [beta]-sheet domains of [beta]-amyloid: disruption of each [beta]-sheet by N-methyl amino acids. Biochemistry 2006; 45: 9485-95.
-
(2006)
Biochemistry
, vol.45
, pp. 9485-9495
-
-
Sciarretta, K.L.1
Boire, A.2
Gordon, D.J.3
Meredith, S.C.4
-
49
-
-
69749090512
-
On the mechanism of nonspecific inhibitors of protein aggregation: Dissecting the interactions of β-synuclein with congo red and lacmoid
-
Lendel C, Bertoncini CW, Cremades N, et al. On the mechanism of nonspecific inhibitors of protein aggregation: dissecting the interactions of [1]-synuclein with congo red and lacmoid. Biochemistry 2009; 48: 8322-34.
-
(2009)
Biochemistry
, vol.48
, pp. 8322-8334
-
-
Lendel, C.1
Bertoncini, C.W.2
Cremades, N.3
-
50
-
-
84255160885
-
Coffee components inhibit amyloid formation of human islet amyloid polypeptide in vitro: Possible link between coffee consumption and diabetes mellitus
-
Cheng B, Liu X, Gong H, et al. Coffee components inhibit amyloid formation of human islet amyloid polypeptide in vitro: possible link between coffee consumption and diabetes mellitus. J Agricultural Food Chem 2011; 59: 13147-55.
-
(2011)
J Agricultural Food Chem
, vol.59
, pp. 13147-13155
-
-
Cheng, B.1
Liu, X.2
Gong, H.3
-
51
-
-
33745096194
-
Inhibition of amyloid fibril formation by polyphenols: Structural similarity and aromatic interactions as a common inhibition mechanism
-
Porat Y, Abramowitz A, Gazit E. Inhibition of amyloid fibril formation by polyphenols: structural similarity and aromatic interactions as a common inhibition mechanism. Chem Biol Drug Des 2006; 67: 27-37.
-
(2006)
Chem Biol Drug Des
, vol.67
, pp. 27-37
-
-
Porat, Y.1
Abramowitz, A.2
Gazit, E.3
-
53
-
-
33847192092
-
Oxidative damage, protein synthesis, and protein degradation in alzheimers disease
-
Ding Q, Dimayuga E, Keller JN. Oxidative damage, protein synthesis, and protein degradation in alzheimers disease. Curr Alzheimer Res 2007; 4: 73-9.
-
(2007)
Curr Alzheimer Res
, vol.4
, pp. 73-79
-
-
Ding, Q.1
Dimayuga, E.2
Keller, J.N.3
-
54
-
-
24644438783
-
Ferulic acid destabilizes preformed β-amyloid fibrils in vitro
-
Ono K, Hirohata M, Yamada M. Ferulic acid destabilizes preformed-amyloid fibrils in vitro. Biochemical Biophys Res Comm 2005; 336: 444-9.
-
(2005)
Biochemical Biophys Res Comm
, vol.336
, pp. 444-449
-
-
Ono, K.1
Hirohata, M.2
Yamada, M.3
-
55
-
-
0034986151
-
Protection against β-amyloid peptide toxicity in vivo with long-term administration of ferulic acid
-
Yan JJ, Cho JY, Kim HS, et al. Protection against-amyloid peptide toxicity in vivo with long-term administration of ferulic acid. Br J Pharmacol 2001; 133: 89-96.
-
(2001)
Br J Pharmacol
, vol.133
, pp. 89-96
-
-
Yan, J.J.1
Cho, J.Y.2
Kim, H.S.3
-
56
-
-
13644265462
-
Ferulic acid ethyl ester protects neurons against amyloid β-peptide(1-42)-induced oxidative stress and neurotoxicity: Relationship to antioxidant activity
-
Sultana R, Ravagna A, Mohmmad-Abdul H, Calabrese V, Butterfield DA. Ferulic acid ethyl ester protects neurons against amyloid β-peptide(1-42)-induced oxidative stress and neurotoxicity: relationship to antioxidant activity. J Neurochem 2005; 92: 749-58.
-
(2005)
J Neurochem
, vol.92
, pp. 749-758
-
-
Sultana, R.1
Ravagna, A.2
Mohmmad-Abdul, H.3
Calabrese, V.4
Butterfield, D.A.5
-
57
-
-
0036313066
-
Nordihydroguaiaretic acid potently breaks down pre-formed Alzheimer's β-amyloid fibrils in vitro
-
Ono K, Hasegawa K, Yoshiike Y, Takashima A, Yamada M, Naiki H. Nordihydroguaiaretic acid potently breaks down pre-formed Alzheimer's β-amyloid fibrils in vitro. J Neurochem 2002; 81: 434-40.
-
(2002)
J Neurochem
, vol.81
, pp. 434-440
-
-
Ono, K.1
Hasegawa, K.2
Yoshiike, Y.3
Takashima, A.4
Yamada, M.5
Naiki, H.6
-
58
-
-
0036838889
-
Nicotine breaks down preformed Alzheimer's β-amyloid fibrils in vitro
-
Ono K, Hasegawa K, Yamada M, Naiki H. Nicotine breaks down preformed Alzheimer's β-amyloid fibrils in vitro. Biological Psychiatry 2002; 52: 880-6.
-
(2002)
Biological Psychiatry
, vol.52
, pp. 880-886
-
-
Ono, K.1
Hasegawa, K.2
Yamada, M.3
Naiki, H.4
-
59
-
-
1542364225
-
Curcumin has potent anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro
-
Ono K, Hasegawa K, Naiki H, Yamada M. Curcumin has potent anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro. J Neurosci Res 2004; 75: 742-50.
-
(2004)
J Neurosci Res
, vol.75
, pp. 742-750
-
-
Ono, K.1
Hasegawa, K.2
Naiki, H.3
Yamada, M.4
-
60
-
-
33751170680
-
Consensus features in amyloid fibrils: Sheet-sheet recognition via a (polar or nonpolar) zipper structure
-
Zheng J, Ma B, Nussinov R. Consensus features in amyloid fibrils: sheet-sheet recognition via a (polar or nonpolar) zipper structure. Physical Biology 2006; 3: P1-P4.
-
(2006)
Physical Biology
, vol.3
-
-
Zheng, J.1
Ma, B.2
Nussinov, R.3
-
62
-
-
33749522024
-
Peptide-based inhibitors of amyloid assembly
-
Indu K, Ronald W, Academic Press
-
Sciarretta KL, Gordon DJ, Meredith SC. Peptide-based inhibitors of amyloid assembly. In: Indu K, Ronald W, ed.^eds., Methods in Enzymology. Academic Press 2006; pp. 273-312.
-
(2006)
Methods In Enzymology
, pp. 273-312
-
-
Sciarretta, K.L.1
Gordon, D.J.2
Meredith, S.C.3
-
63
-
-
34247234602
-
The Alzheimer's peptides A[beta]40 and 42 adopt distinct conformations in water: A combined MD/NMR study
-
Sgourakis NG, Yan Y, McCallum SA, Wang C, Garcia AE. The Alzheimer's peptides A[beta]40 and 42 adopt distinct conformations in water: a combined MD/NMR study. J Mol Biol 2007; 368: 1448-57.
-
(2007)
J Mol Biol
, vol.368
, pp. 1448-1457
-
-
Sgourakis, N.G.1
Yan, Y.2
McCallum, S.A.3
Wang, C.4
Garcia, A.E.5
-
64
-
-
25844493112
-
Capturing intermediate structures of alzheimer's beta-amyloid, Abeta(1-40), by solid-state NMR spectroscopy
-
Chimon S, Ishii Y. Capturing intermediate structures of alzheimer's beta-amyloid, Abeta(1-40), by solid-state NMR spectroscopy. J Am Chem Soc 2005; 127: 13472-3.
-
(2005)
J Am Chem Soc
, vol.127
, pp. 13472-13473
-
-
Chimon, S.1
Ishii, Y.2
-
65
-
-
33644851439
-
The solvent protection of alzheimer amyloid-beta-(1-42) fibrils as determined by solution NMR spectroscopy
-
Olofsson A, Sauer-Eriksson AE, Ohman A. The solvent protection of alzheimer amyloid-beta-(1-42) fibrils as determined by solution NMR spectroscopy. J Biol Chem 2006; 281: 477-83.
-
(2006)
J Biol Chem
, vol.281
, pp. 477-483
-
-
Olofsson, A.1
Sauer-Eriksson, A.E.2
Ohman, A.3
-
66
-
-
52949100595
-
C-terminal peptides coassemble into Abeta42 oligomers and protect neurons against Abeta42-induced neurotoxicity
-
Fradinger EA, Monien BH, Urbanc B, et al. C-terminal peptides coassemble into Abeta42 oligomers and protect neurons against Abeta42-induced neurotoxicity. Proc Natl Acad Sci USA 2008; 105: 14175-80.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 14175-14180
-
-
Fradinger, E.A.1
Monien, B.H.2
Urbanc, B.3
-
67
-
-
0026619343
-
Substitutions of hydrophobic amino acids reduce the amyloidogenicity of Alzheimer's disease βA4 peptides
-
Hilbich C, Kisters-Woike B, Reed J, Masters CL, Beyreuther K. Substitutions of hydrophobic amino acids reduce the amyloidogenicity of Alzheimer's disease βA4 peptides. J Mol Biol 1992; 228: 460-73.
-
(1992)
J Mol Biol
, vol.228
, pp. 460-473
-
-
Hilbich, C.1
Kisters-Woike, B.2
Reed, J.3
Masters, C.L.4
Beyreuther, K.5
-
68
-
-
0030600371
-
Inhibition of Alzheimer's amyloidosis by peptides that prevent beta-sheet conformation
-
Soto C, Kindy MS, Baumann M, Frangione B. Inhibition of Alzheimer's amyloidosis by peptides that prevent beta-sheet conformation. Biochem Biophys Res Commun. 1996; 226: 672-80.
-
(1996)
Biochem Biophys Res Commun
, vol.226
, pp. 672-680
-
-
Soto, C.1
Kindy, M.S.2
Baumann, M.3
Frangione, B.4
-
69
-
-
0029994633
-
Arrest of beta-amyloid fibril formation by a pentapeptide ligand
-
Tjernberg LO, Näslund J, Lindqvist F, et al. Arrest of beta-amyloid fibril formation by a pentapeptide ligand. J Biol Chem 1996; 271: 8545-8.
-
(1996)
J Biol Chem
, vol.271
, pp. 8545-8548
-
-
Tjernberg, L.O.1
Näslund, J.2
Lindqvist, F.3
-
70
-
-
28544452382
-
Structure and Orientation of Peptide Inhibitors Bound to Beta-amyloid Fibrils
-
Chen Z, Krause G, Reif B. Structure and Orientation of Peptide Inhibitors Bound to Beta-amyloid Fibrils. J Mol Biol 2005; 354: 760-76.
-
(2005)
J Mol Biol
, vol.354
, pp. 760-776
-
-
Chen, Z.1
Krause, G.2
Reif, B.3
-
71
-
-
0036095659
-
Design and characterization of a membrane permeable N-methyl amino acid-containing peptide that inhibits Abeta1-40 fibrillogenesis
-
Gordon DJ, Tappe R, Meredith SC. Design and characterization of a membrane permeable N-methyl amino acid-containing peptide that inhibits Abeta1-40 fibrillogenesis. J Peptide Res 2002; 60: 37-55.
-
(2002)
J Peptide Res
, vol.60
, pp. 37-55
-
-
Gordon, D.J.1
Tappe, R.2
Meredith, S.C.3
-
72
-
-
0035902507
-
Inhibition of β-Amyloid(40) fibrillogenesis and disassembly of β-Amyloid(40) fibrils by short β-Amyloid congeners containing N-methyl amino acids at alternate residues
-
Gordon DJ, Sciarretta KL, Meredith SC. Inhibition of β-Amyloid(40) fibrillogenesis and disassembly of β-Amyloid(40) fibrils by short β-Amyloid congeners containing N-methyl amino acids at alternate residues. Biochemistry 2001; 40: 8237-45.
-
(2001)
Biochemistry
, vol.40
, pp. 8237-8245
-
-
Gordon, D.J.1
Sciarretta, K.L.2
Meredith, S.C.3
-
73
-
-
0031873102
-
Beta-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: Implications for Alzheimer's therapy
-
Soto C, Sigurdsson EM, Morelli L, Kumar RA, Castaño EM, Frangione B. Beta-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: implications for Alzheimer's therapy. Nature Med 1998; 4: 822-6.
-
(1998)
Nature Med
, vol.4
, pp. 822-826
-
-
Soto, C.1
Sigurdsson, E.M.2
Morelli, L.3
Kumar, R.A.4
Castaño, E.M.5
Frangione, B.6
-
74
-
-
52949100595
-
C-terminal peptides coassemble into Aβ42 oligomers and protect neurons against Aβ42-induced neurotoxicity
-
Fradinger EA, Monien BH, Urbanc B, et al. C-terminal peptides coassemble into A[1]42 oligomers and protect neurons against Aβ42-induced neurotoxicity. PNAS 2008; 105: 14175-80.
-
(2008)
PNAS
, vol.105
, pp. 14175-14180
-
-
Fradinger, E.A.1
Monien, B.H.2
Urbanc, B.3
-
76
-
-
14944378094
-
Certain inhibitors of synthetic amyloid β-peptide (Aβ) fibrillogenesis block oligomerization of natural Aβ and thereby rescue long-term potentiation
-
Walsh DM, Townsend M, Podlisny MB, et al. Certain inhibitors of synthetic amyloid β-peptide (Aβ) fibrillogenesis block oligomerization of natural Aβ and thereby rescue long-term potentiation. J Neurosci 2005; 25: 2455-62.
-
(2005)
J Neurosci
, vol.25
, pp. 2455-2462
-
-
Walsh, D.M.1
Townsend, M.2
Podlisny, M.B.3
-
77
-
-
39649124929
-
Designing peptide inhibitors for oligomerization and toxicity of alzheimer's β-amyloid peptide
-
Austen BM, Paleologou KE, Ali SAE, Qureshi MM, Allsop D, El-Agnaf OMA. Designing peptide inhibitors for oligomerization and toxicity of alzheimer's β-amyloid peptide. Biochemistry 2008; 47: 1984-92.
-
(2008)
Biochemistry
, vol.47
, pp. 1984-1992
-
-
Austen, B.M.1
Paleologou, K.E.2
Ali, S.A.E.3
Qureshi, M.M.4
Allsop, D.5
El-Agnaf, O.M.A.6
-
78
-
-
34247197575
-
IAPP mimic blocks Aβ cytotoxic self-assembly: Crosssuppression of amyloid toxicity of Aβ and IAPP suggests a molecular link between Alzheimer's disease and type II diabetes
-
Yan LM, Velkova A, Tatarek-Nossol M, Andreetto E, Kapurniotu A. IAPP mimic blocks Aβ cytotoxic self-assembly: crosssuppression of amyloid toxicity of Aβ and IAPP suggests a molecular link between Alzheimer's disease and type II diabetes. Ange Chem Inter Ed 2007; 46: 1246-52.
-
(2007)
Ange Chem Inter Ed
, vol.46
, pp. 1246-1252
-
-
Yan, L.M.1
Velkova, A.2
Tatarek-Nossol, M.3
Andreetto, E.4
Kapurniotu, A.5
-
79
-
-
33144464982
-
Design of a mimic of nonamyloidogenic and bioactive human islet amyloid polypeptide (IAPP) as nanomolar affinity inhibitor of IAPP cytotoxic fibrillogenesis
-
Yan LM, Tatarek-Nossol M, Velkova A, Kazantzis A, Kapurniotu A. Design of a mimic of nonamyloidogenic and bioactive human islet amyloid polypeptide (IAPP) as nanomolar affinity inhibitor of IAPP cytotoxic fibrillogenesis. Proc Natl Acad Sci USA 2006; 103: 2046-51.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 2046-2051
-
-
Yan, L.M.1
Tatarek-Nossol, M.2
Velkova, A.3
Kazantzis, A.4
Kapurniotu, A.5
-
80
-
-
79957512886
-
Interaction between amyloid beta peptide and an aggregation blocker peptide mimicking islet amyloid polypeptide
-
Rezaei-Ghaleh N, Andreetto E, Yan LM, Kapurniotu A, Zweckstetter M. Interaction between amyloid beta peptide and an aggregation blocker peptide mimicking islet amyloid polypeptide. PLoS ONE 2011; 6: e20289.
-
(2011)
PLoS ONE
, vol.6
-
-
Rezaei-Ghaleh, N.1
Andreetto, E.2
Yan, L.M.3
Kapurniotu, A.4
Zweckstetter, M.5
-
81
-
-
4644293577
-
Conformation-dependent antibodies target diseases of protein misfolding
-
Glabe CG. Conformation-dependent antibodies target diseases of protein misfolding. Trends Biochem Sci 2004; 29: 542-7.
-
(2004)
Trends Biochem Sci
, vol.29
, pp. 542-547
-
-
Glabe, C.G.1
-
82
-
-
23044442730
-
The Clinical and Biological Relationship between Type II Diabetes Mellitus and Alzheimers Disease
-
Nicolls MR. The Clinical and Biological Relationship between Type II Diabetes Mellitus and Alzheimers Disease. Curr Alzheimer Res 2004; 1: 47-54.
-
(2004)
Curr Alzheimer Res
, vol.1
, pp. 47-54
-
-
Nicolls, M.R.1
-
83
-
-
0035984812
-
Apolipoprotein-mediated transport of nanoparticle-bound drugs across the blood-brain barrier
-
Kreuter J, Shamenkov D, Petrov V, et al. Apolipoprotein-mediated transport of nanoparticle-bound drugs across the blood-brain barrier. J Drug Target 2002; 10: 317-25.
-
(2002)
J Drug Target
, vol.10
, pp. 317-325
-
-
Kreuter, J.1
Shamenkov, D.2
Petrov, V.3
-
84
-
-
0035937595
-
Nanoparticulate systems for brain delivery of drugs
-
Kreuter J. Nanoparticulate systems for brain delivery of drugs. Adv Drug Deliv Rev 2001; 47: 65-81.
-
(2001)
Adv Drug Deliv Rev
, vol.47
, pp. 65-81
-
-
Kreuter, J.1
-
85
-
-
27744599588
-
Targeted nanoparticles for drug delivery through the blood-brain barrier for Alzheimer's disease
-
Roney C, Kulkarni P, Arora V, et al. Targeted nanoparticles for drug delivery through the blood-brain barrier for Alzheimer's disease. J Control Release 2005; 108: 193-214.
-
(2005)
J Control Release
, vol.108
, pp. 193-214
-
-
Roney, C.1
Kulkarni, P.2
Arora, V.3
-
86
-
-
61449106525
-
Effect of nanoparticles on protein folding and fibrillogenesis
-
Fei L, Perrett S. Effect of nanoparticles on protein folding and fibrillogenesis. Int J Mol Sci 2009; 10: 646-55.
-
(2009)
Int J Mol Sci
, vol.10
, pp. 646-655
-
-
Fei, L.1
Perrett, S.2
-
87
-
-
58149102337
-
Gold nanoparticles in biology: Beyond toxicity to cellular imaging
-
Murphy CJ, Gole AM, Stone JW, et al. Gold nanoparticles in biology: beyond toxicity to cellular imaging. Acc Chem Res 2008; 41: 1721-30.
-
(2008)
Acc Chem Res
, vol.41
, pp. 1721-1730
-
-
Murphy, C.J.1
Gole, A.M.2
Stone, J.W.3
-
88
-
-
25444448098
-
Gold nanoparticles are taken up by human cells but do not cause acute cytotoxicity
-
Connor EE, Mwamuka J, Gole A, Murphy CJ, Wyatt MD. Gold nanoparticles are taken up by human cells but do not cause acute cytotoxicity. Small 2005; 1: 325-7.
-
(2005)
Small
, vol.1
, pp. 325-327
-
-
Connor, E.E.1
Mwamuka, J.2
Gole, A.3
Murphy, C.J.4
Wyatt, M.D.5
-
89
-
-
84880062949
-
Gold Nanospheres as Inhibitors of Amyloid-β Protein Aggregation Involved in Alzheimer's Disease
-
Mihyun Lim DS-O, Rahina Mahtab, and Melissa A. Moss. Gold Nanospheres as Inhibitors of Amyloid-β Protein Aggregation Involved in Alzheimer's Disease. J South Carolina Acad Sci 2011; 9: 14.
-
(2011)
J South Carolina Acad Sci
, vol.9
, pp. 14
-
-
Mihyun Lim, D.S.-O.1
Mahtab, R.2
Moss, M.A.3
-
90
-
-
31544459915
-
Nanoparticle-mediated local and remote manipulation of protein aggregation
-
Kogan MJ, Bastus NG, Amigo R, et al. Nanoparticle-mediated local and remote manipulation of protein aggregation. Nano Letters 2006; 6: 110-5.
-
(2006)
Nano Letters
, vol.6
, pp. 110-115
-
-
Kogan, M.J.1
Bastus, N.G.2
Amigo, R.3
-
92
-
-
45749115053
-
How changes in the sequence of the peptide CLPFFD-NH2 can modify the conjugation and stability of gold nanoparticles and their affinity for beta-amyloid fibrils
-
Olmedo I, Araya E, Sanz F, et al. How changes in the sequence of the peptide CLPFFD-NH2 can modify the conjugation and stability of gold nanoparticles and their affinity for beta-amyloid fibrils. Bioconjug Chem 2008; 19: 1154-63.
-
(2008)
Bioconjug Chem
, vol.19
, pp. 1154-1163
-
-
Olmedo, I.1
Araya, E.2
Sanz, F.3
-
93
-
-
54949120918
-
Gold Nanoparticles and Microwave Irradiation Inhibit Beta-Amyloid Amyloidogenesis
-
Araya E, Olmedo I, Bastus NG, Guerrero S, Puntes VF, Giralt E, Kogan MJ. Gold Nanoparticles and Microwave Irradiation Inhibit Beta-Amyloid Amyloidogenesis. Nanoscale Res Letters 2008; 3: 435-43.
-
(2008)
Nanoscale Res Letters
, vol.3
, pp. 435-443
-
-
Araya, E.1
Olmedo, I.2
Bastus, N.G.3
Guerrero, S.4
Puntes, V.F.5
Giralt, E.6
Kogan, M.J.7
-
94
-
-
79956156448
-
Inhibition of Amyloid Peptide Fibrillation by Inorganic Nanoparticles: Functional Similarities with Proteins
-
Yoo SI, Yang M, Brender JR, et al. Inhibition of Amyloid Peptide Fibrillation by Inorganic Nanoparticles: Functional Similarities with Proteins. Angewandte Chemie-Int Edition 2011; 50: 5110-5.
-
(2011)
Angewandte Chemie-Int Edition
, vol.50
, pp. 5110-5115
-
-
Yoo, S.I.1
Yang, M.2
Brender, J.R.3
-
95
-
-
0037418703
-
Fullerene inhibits beta-amyloid peptide aggregation
-
Kim JE, Lee M. Fullerene inhibits beta-amyloid peptide aggregation. Biochem Biophys Res Commun 2003; 303: 576-9.
-
(2003)
Biochem Biophys Res Commun
, vol.303
, pp. 576-579
-
-
Kim, J.E.1
Lee, M.2
-
96
-
-
33750052628
-
PEGylated phospholipid nanomicelles interact with beta-amyloid((1-42)) and mitigate its beta-sheet formation, aggregation and neurotoxicity in vitro
-
Pai AS, Rubinstein I, Onyuksel H. PEGylated phospholipid nanomicelles interact with beta-amyloid((1-42)) and mitigate its beta-sheet formation, aggregation and neurotoxicity in vitro. Peptides 2006; 27: 2858-66.
-
(2006)
Peptides
, vol.27
, pp. 2858-2866
-
-
Pai, A.S.1
Rubinstein, I.2
Onyuksel, H.3
-
97
-
-
56449124781
-
Inhibition of amyloid beta protein fibrillation by polymeric nanoparticles
-
Cabaleiro-Lago C, Quinlan-Pluck F, Lynch I, et al. Inhibition of amyloid beta protein fibrillation by polymeric nanoparticles. J Am Chem Soc 2008; 130: 15437-43.
-
(2008)
J Am Chem Soc
, vol.130
, pp. 15437-15443
-
-
Cabaleiro-Lago, C.1
Quinlan-Pluck, F.2
Lynch, I.3
-
98
-
-
70350348150
-
Inhibition of beta 1-40 amyloid fibrillation with N-acetyl-L-cysteine capped quantum dots
-
Xiao L, Zhao D, Chan WH, Choi MM, Li HW. Inhibition of beta 1-40 amyloid fibrillation with N-acetyl-L-cysteine capped quantum dots. Biomaterials 2010; 31: 91-8.
-
(2010)
Biomaterials
, vol.31
, pp. 91-98
-
-
Xiao, L.1
Zhao, D.2
Chan, W.H.3
Choi, M.M.4
Li, H.W.5
-
99
-
-
0033136579
-
Molecular chaperone-like activity of hydrogel nanoparticles of hydrophobized pullulan: Thermal stabilization with refolding of carbonic anhydrase B
-
Akiyoshi K, Sasaki Y, Sunamoto J. Molecular chaperone-like activity of hydrogel nanoparticles of hydrophobized pullulan: thermal stabilization with refolding of carbonic anhydrase B. Bioconjug Chem 1999; 10: 321-4.
-
(1999)
Bioconjug Chem
, vol.10
, pp. 321-324
-
-
Akiyoshi, K.1
Sasaki, Y.2
Sunamoto, J.3
-
100
-
-
14044266150
-
Thermoresponsive controlled association of protein with a dynamic nanogel of hydrophobized polysaccharide and cyclodextrin: Heat shock protein-like activity of artificial molecular chaperone
-
Nomura Y, Sasaki Y, Takagi M, Narita T, Aoyama Y, Akiyoshi K. Thermoresponsive controlled association of protein with a dynamic nanogel of hydrophobized polysaccharide and cyclodextrin: heat shock protein-like activity of artificial molecular chaperone. Biomacromolecules 2005; 6: 447-52.
-
(2005)
Biomacromolecules
, vol.6
, pp. 447-452
-
-
Nomura, Y.1
Sasaki, Y.2
Takagi, M.3
Narita, T.4
Aoyama, Y.5
Akiyoshi, K.6
-
101
-
-
37849186419
-
Inhibition of the formation of amyloid beta-protein fibrils using biocompatible nanogels as artificial chaperones
-
Ikeda K, Okada T, Sawada S, Akiyoshi K, Matsuzaki K. Inhibition of the formation of amyloid beta-protein fibrils using biocompatible nanogels as artificial chaperones. FEBS Lett 2006; 580: 6587-95.
-
(2006)
FEBS Lett
, vol.580
, pp. 6587-6595
-
-
Ikeda, K.1
Okada, T.2
Sawada, S.3
Akiyoshi, K.4
Matsuzaki, K.5
-
102
-
-
48849114891
-
Influence of fluorinated and hydrogenated nanoparticles on the structure and fibrillogenesis of amyloid betapeptide
-
Rocha S, Thunemann AF, Pereira Mdo C, Coelho M, Mohwald H, Brezesinski G. Influence of fluorinated and hydrogenated nanoparticles on the structure and fibrillogenesis of amyloid betapeptide. Biophys Chem 2008; 137: 35-42.
-
(2008)
Biophys Chem
, vol.137
, pp. 35-42
-
-
Rocha, S.1
Thunemann, A.F.2
Pereira Mdo, C.3
Coelho, M.4
Mohwald, H.5
Brezesinski, G.6
-
103
-
-
33748202940
-
Nanoparticle iron chelators: A new therapeutic approach in Alzheimer disease and other neurologic disorders associated with trace metal imbalance
-
Liu G, Men P, Harris PL, Rolston RK, Perry G, Smith MA. Nanoparticle iron chelators: a new therapeutic approach in Alzheimer disease and other neurologic disorders associated with trace metal imbalance. Neurosci Lett 2006; 406: 189-93.
-
(2006)
Neurosci Lett
, vol.406
, pp. 189-193
-
-
Liu, G.1
Men, P.2
Harris, P.L.3
Rolston, R.K.4
Perry, G.5
Smith, M.A.6
-
104
-
-
64049104164
-
Nanoparticle-chelator conjugates as inhibitors of amyloid-beta aggregation and neurotoxicity: A novel therapeutic approach for Alzheimer disease
-
Liu G, Men P, Kudo W, Perry G, Smith MA. Nanoparticle-chelator conjugates as inhibitors of amyloid-beta aggregation and neurotoxicity: a novel therapeutic approach for Alzheimer disease. Neurosci Lett 2009; 455: 187-90.
-
(2009)
Neurosci Lett
, vol.455
, pp. 187-190
-
-
Liu, G.1
Men, P.2
Kudo, W.3
Perry, G.4
Smith, M.A.5
-
105
-
-
12344251715
-
Novel D-penicillamine carrying nanoparticles for metal chelation therapy in Alzheimer's and other CNS diseases
-
Cui Z, Lockman PR, Atwood CS, et al. Novel D-penicillamine carrying nanoparticles for metal chelation therapy in Alzheimer's and other CNS diseases. Eur J Pharm Biopharm 2005; 59: 263-72.
-
(2005)
Eur J Pharm Biopharm
, vol.59
, pp. 263-272
-
-
Cui, Z.1
Lockman, P.R.2
Atwood, C.S.3
-
106
-
-
0034851810
-
Dendrimers: A review of their appeal and applications
-
Dykes GM. Dendrimers: a review of their appeal and applications. J Chem Technol Biotechnol 2001; 76: 903-18.
-
(2001)
J Chem Technol Biotechnol
, vol.76
, pp. 903-918
-
-
Dykes, G.M.1
-
107
-
-
84868159999
-
Syntheses of sulfo-glycodendrimers using click chemistry and their biological evaluation
-
Miura Y, Onogi S, Fukuda T. Syntheses of sulfo-glycodendrimers using click chemistry and their biological evaluation. Molecules 2012; 17: 11877-96.
-
(2012)
Molecules
, vol.17
, pp. 11877-11896
-
-
Miura, Y.1
Onogi, S.2
Fukuda, T.3
-
109
-
-
81255152309
-
Dense Shell Glycodendrimers as Potential Nontoxic Anti-amyloidogenic Agents in Alzheimer's Disease. Amyloid-Dendrimer Aggregates Morphology and Cell Toxicity
-
Klementieva O, Benseny-Cases N, Gella A, Appelhans D, Voit B, Cladera J. Dense Shell Glycodendrimers as Potential Nontoxic Anti-amyloidogenic Agents in Alzheimer's Disease. Amyloid-Dendrimer Aggregates Morphology and Cell Toxicity. Biomacromolecules 2011; 12: 3903-9.
-
(2011)
Biomacromolecules
, vol.12
, pp. 3903-3909
-
-
Klementieva, O.1
Benseny-Cases, N.2
Gella, A.3
Appelhans, D.4
Voit, B.5
Cladera, J.6
-
110
-
-
35348934391
-
Branched KLVFF tetramers strongly potentiate inhibition of beta-amyloid aggregation
-
Chafekar SM, Malda H, Merkx M, et al. Branched KLVFF tetramers strongly potentiate inhibition of beta-amyloid aggregation. Chembiochem 2007; 8: 1857-64.
-
(2007)
Chembiochem
, vol.8
, pp. 1857-1864
-
-
Chafekar, S.M.1
Malda, H.2
Merkx, M.3
-
111
-
-
84867892719
-
Dendrimers reduce toxicity of Abeta 1-28 peptide during aggregation and accelerate fibril formation
-
Klajnert B, Wasiak T, Ionov M, et al. Dendrimers reduce toxicity of Abeta 1-28 peptide during aggregation and accelerate fibril formation. Nanomedicine 2012; 8: 1372-8.
-
(2012)
Nanomedicine
, vol.8
, pp. 1372-1378
-
-
Klajnert, B.1
Wasiak, T.2
Ionov, M.3
-
112
-
-
70349647479
-
Inhibition of Aβ42 aggregation using peptides selected from combinatorial libraries
-
Baine M, Georgie DS, Shiferraw EZ, Nguyen TPT, Nogaj LA, Moffet DA. Inhibition of Aβ42 aggregation using peptides selected from combinatorial libraries. J Peptide Sci 2009; 15: 499-503.
-
(2009)
J Peptide Sci
, vol.15
, pp. 499-503
-
-
Baine, M.1
Georgie, D.S.2
Shiferraw, E.Z.3
Nguyen, T.P.T.4
Nogaj, L.A.5
Moffet, D.A.6
-
113
-
-
77955841406
-
Candidate anti-Aβ fluorene compounds selected from analogs of amyloid imaging agents
-
Hong HS, Maezawa I, Budamagunta M, et al. Candidate anti-Aβ fluorene compounds selected from analogs of amyloid imaging agents. Neurobiol Aging 2010; 31: 1690-9.
-
(2010)
Neurobiol Aging
, vol.31
, pp. 1690-1699
-
-
Hong, H.S.1
Maezawa, I.2
Budamagunta, M.3
-
114
-
-
0033613188
-
De novo amyloid proteins from designed combinatorial libraries
-
West MW, Wang W, Patterson J, Mancias JD, Beasley JR, Hecht MH. De novo amyloid proteins from designed combinatorial libraries. Proc Natl Acad Sci USA 1999; 96: 11211-6.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 11211-11216
-
-
West, M.W.1
Wang, W.2
Patterson, J.3
Mancias, J.D.4
Beasley, J.R.5
Hecht, M.H.6
-
115
-
-
0037022661
-
Rationally designed mutations convert de novo amyloid-like fibrils into monomeric β-sheet proteins
-
Wang W, Hecht MH. Rationally designed mutations convert de novo amyloid-like fibrils into monomeric β-sheet proteins. Proc Natl Acad Sci USA 2002; 99: 2760-5.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 2760-2765
-
-
Wang, W.1
Hecht, M.H.2
-
116
-
-
33750449952
-
A highthroughput screen for compounds that inhibit aggregation of the Alzheimer's peptide
-
Kim W, Kim Y, Min J, Kim DJ, Chang YT, Hecht MH. A highthroughput screen for compounds that inhibit aggregation of the Alzheimer's peptide. ACS Chemical Biol 2006; 1: 461-9.
-
(2006)
ACS Chemical Biol
, vol.1
, pp. 461-469
-
-
Kim, W.1
Kim, Y.2
Min, J.3
Kim, D.J.4
Chang, Y.T.5
Hecht, M.H.6
-
117
-
-
77649240855
-
Identifying the amylome, proteins capable of forming amyloid-like fibrils
-
Goldschmidt L, Teng PK, Riek R, Eisenberg D. Identifying the amylome, proteins capable of forming amyloid-like fibrils. PNAS 2010; 107: 3487-92.
-
(2010)
PNAS
, vol.107
, pp. 3487-3492
-
-
Goldschmidt, L.1
Teng, P.K.2
Riek, R.3
Eisenberg, D.4
-
118
-
-
78649582429
-
Nonsteroidal antiinflammatory drug naproxen destabilizes Aβ amyloid fibrils: A molecular dynamics investigation
-
Takeda T, Kumar R, Raman EP, Klimov DK. Nonsteroidal antiinflammatory drug naproxen destabilizes Aβ amyloid fibrils: a molecular dynamics investigation. J Phys Chem B 2010; 114: 15394-402.
-
(2010)
J Phys Chem B
, vol.114
, pp. 15394-15402
-
-
Takeda, T.1
Kumar, R.2
Raman, E.P.3
Klimov, D.K.4
-
119
-
-
77957959117
-
Binding of nonsteroidal anti-inflammatory drugs to Aβ fibril. Proteins: Structure
-
Takeda T, Chang WE, Raman EP, Klimov DK. Binding of nonsteroidal anti-inflammatory drugs to Aβ fibril. Proteins: Structure, Function, and Bioinformatics 2010; 78: 2849-60.
-
(2010)
Function, and Bioinformatics
, vol.78
, pp. 2849-2860
-
-
Takeda, T.1
Chang, W.E.2
Raman, E.P.3
Klimov, D.K.4
-
120
-
-
79953839293
-
On the origin of the stronger binding of PIB over thioflavin T to protofibrils of the Alzheimer amyloid-β peptide: A molecular dynamics study
-
Wu C, Bowers Michael T, Shea JE. On the origin of the stronger binding of PIB over thioflavin T to protofibrils of the Alzheimer amyloid-β peptide: a molecular dynamics study. Biophysical J 2011; 100: 1316-24.
-
(2011)
Biophysical J
, vol.100
, pp. 1316-1324
-
-
Wu, C.1
Bowers Michael, T.2
Shea, J.E.3
-
121
-
-
67650091797
-
Computational selection of inhibitors of A[beta] aggregation and neuronal toxicity
-
Chen D, Martin ZS, Soto C, Schein CH. Computational selection of inhibitors of A[beta] aggregation and neuronal toxicity. Bioorg Med Chem 2009; 17: 5189-97.
-
(2009)
Bioorg Med Chem
, vol.17
, pp. 5189-5197
-
-
Chen, D.1
Martin, Z.S.2
Soto, C.3
Schein, C.H.4
-
122
-
-
63449099645
-
Fibril aggregation inhibitory activity of the β-sheet breaker peptides: A molecular docking approach
-
Chini MG, Scrima M, D'Ursi AM, Bifulco G. Fibril aggregation inhibitory activity of the β-sheet breaker peptides: a molecular docking approach. J Pept Sci 2009; 15: 229-34.
-
(2009)
J Pept Sci
, vol.15
, pp. 229-234
-
-
Chini, M.G.1
Scrima, M.2
D'Ursi, A.M.3
Bifulco, G.4
-
123
-
-
77952996946
-
Molecular dynamics simulations of anti-aggregation effect of ibuprofen
-
Chang WE, Takeda T, Raman EP, Klimov DK. Molecular dynamics simulations of anti-aggregation effect of ibuprofen. Biophys J 2010; 98: 2662-70.
-
(2010)
Biophys J
, vol.98
, pp. 2662-2670
-
-
Chang, W.E.1
Takeda, T.2
Raman, E.P.3
Klimov, D.K.4
-
124
-
-
32344451179
-
The alpha-to-beta Conformational Transition of Alzheimer's Abeta-(1-42) Peptide in Aqueous Media is Reversible: A Step by Step Conformational Analysis Suggests the Location of beta Conformation Seeding
-
Tomaselli S, Esposito V, Vangone P, et al. The alpha-to-beta Conformational Transition of Alzheimer's Abeta-(1-42) Peptide in Aqueous Media is Reversible: A Step by Step Conformational Analysis Suggests the Location of beta Conformation Seeding. ChemBioChem 2006; 7: 257-67.
-
(2006)
ChemBioChem
, vol.7
, pp. 257-267
-
-
Tomaselli, S.1
Esposito, V.2
Vangone, P.3
-
125
-
-
77957829326
-
Molecular dynamics simulations of Aβ fibril interactions with β-sheet breaker peptides
-
Bruce NJ, Chen D, Dastidar SG, Marks GE, Schein CH, Bryce RA. Molecular dynamics simulations of Aβ fibril interactions with β-sheet breaker peptides. Peptides 2010; 31: 2100-8.
-
(2010)
Peptides
, vol.31
, pp. 2100-2108
-
-
Bruce, N.J.1
Chen, D.2
Dastidar, S.G.3
Marks, G.E.4
Schein, C.H.5
Bryce, R.A.6
-
126
-
-
0036191829
-
Mapping of possible binding sequences of two beta-sheet breaker peptides on beta amyloid peptide of Alzheimer's disease
-
Hetenyi C, Kortvelyesi T, Penke B. Mapping of possible binding sequences of two beta-sheet breaker peptides on beta amyloid peptide of Alzheimer's disease. Bioorg Med Chem 2002; 10: 1587-93.
-
(2002)
Bioorg Med Chem
, vol.10
, pp. 1587-1593
-
-
Hetenyi, C.1
Kortvelyesi, T.2
Penke, B.3
-
127
-
-
79951815645
-
Alzheimer's disease drug candidates stabilize Aβ protein native structure by interacting with the hydrophobic core
-
Li J, Liu R, Lam KS, Jin L-W, Duan Y. Alzheimer's disease drug candidates stabilize A[1] protein native structure by interacting with the hydrophobic core. Biophysical J 2011; 100: 1076-82.
-
(2011)
Biophysical J
, vol.100
, pp. 1076-1082
-
-
Li, J.1
Liu, R.2
Lam, K.S.3
Jin, L.-W.4
Duan, Y.5
-
128
-
-
52249085846
-
A molecular dynamics study of the interaction of D-peptide amyloid inhibitors with their target sequence reveals a potential inhibitory pharmacophore conformation
-
Esteras-Chopo A, Morra G, Moroni E, Serrano L, Lopez de la Paz M, Colombo G. A molecular dynamics study of the interaction of D-peptide amyloid inhibitors with their target sequence reveals a potential inhibitory pharmacophore conformation. J Mol Biol 2008; 383: 266-80.
-
(2008)
J Mol Biol
, vol.383
, pp. 266-280
-
-
Esteras-Chopo, A.1
Morra, G.2
Moroni, E.3
Serrano, L.4
Lopez de la Paz, M.5
Colombo, G.6
-
129
-
-
33845206150
-
Atomic structures of peptide self-assembly mimics
-
Makabe K, McElheny D, Tereshko V, et al. Atomic structures of peptide self-assembly mimics. PNAS 2006; 103: 17753-8.
-
(2006)
PNAS
, vol.103
, pp. 17753-17758
-
-
Makabe, K.1
McElheny, D.2
Tereshko, V.3
-
130
-
-
34547947641
-
Conversion of non-fibrillar [beta]-sheet oligomers into amyloid fibrils in Alzheimer's disease amyloid peptide aggregation
-
Benseny-Cases N, Cocera M, Cladera J. Conversion of non-fibrillar [beta]-sheet oligomers into amyloid fibrils in Alzheimer's disease amyloid peptide aggregation. Biochem Biophys Res Commun 2007; 361: 916-21.
-
(2007)
Biochem Biophys Res Commun
, vol.361
, pp. 916-921
-
-
Benseny-Cases, N.1
Cocera, M.2
Cladera, J.3
-
131
-
-
33749642847
-
Computational approaches to fibril structure and formation
-
Academic Press
-
Hall CK, Wagoner VA. Computational approaches to fibril structure and formation. In: ed.^eds., Methods in Enzymology. Academic Press 2006; pp. 338-65.
-
(2006)
Methods In Enzymology
, pp. 338-365
-
-
Hall, C.K.1
Wagoner, V.A.2
-
132
-
-
84860112673
-
Inhibition of Aggregation of Amyloid beta42 by Arginine-Containing Small Compounds
-
Kawasaki T, Kamijo S. Inhibition of Aggregation of Amyloid beta42 by Arginine-Containing Small Compounds. Biosci Biotechnol Biochem 2012.
-
(2012)
Biosci Biotechnol Biochem
-
-
Kawasaki, T.1
Kamijo, S.2
-
133
-
-
84858605051
-
A chemical analog of curcumin as an improved inhibitor of amyloid abeta oligomerization
-
Orlando RA, Gonzales AM, Royer RE, Deck LM, Vander Jagt DL. A chemical analog of curcumin as an improved inhibitor of amyloid abeta oligomerization. PLoS One 2012; 7: e31869.
-
(2012)
PLoS One
, vol.7
-
-
Orlando, R.A.1
Gonzales, A.M.2
Royer, R.E.3
Deck, L.M.4
Vander Jagt, D.L.5
-
134
-
-
77951673631
-
Effects of Congo Red on A beta(1-40) Fibril Formation Process and Morphology
-
Bose PP, Chatterjee U, Xie L, Johansson J, Gothelid E, Arvidsson PI. Effects of Congo Red on A beta(1-40) Fibril Formation Process and Morphology. Acs Chem Neurosci 2010; 1: 315-24.
-
(2010)
Acs Chem Neurosci
, vol.1
, pp. 315-324
-
-
Bose, P.P.1
Chatterjee, U.2
Xie, L.3
Johansson, J.4
Gothelid, E.5
Arvidsson, P.I.6
-
135
-
-
33745235789
-
Alzheimer-like plaque formation by human macrophages is reduced by fibrillation inhibitors and lovastatin
-
Gellermann GP, Ullrich K, Tannert A, et al. Alzheimer-like plaque formation by human macrophages is reduced by fibrillation inhibitors and lovastatin. J Mol Biol 2006; 360: 251-7.
-
(2006)
J Mol Biol
, vol.360
, pp. 251-257
-
-
Gellermann, G.P.1
Ullrich, K.2
Tannert, A.3
-
136
-
-
15044339964
-
Intraneuronal A beta, non-amyloid aggregates and neurodegeneration in a Drosophila model of Alzheimer's disease
-
Crowther DC, Kinghorn KJ, Miranda E, et al. Intraneuronal A beta, non-amyloid aggregates and neurodegeneration in a Drosophila model of Alzheimer's disease. Neuroscience 2005; 132: 123-35.
-
(2005)
Neuroscience
, vol.132
, pp. 123-135
-
-
Crowther, D.C.1
Kinghorn, K.J.2
Miranda, E.3
-
138
-
-
43949112301
-
Benzofuran-based hybrid compound's for the inhibition of cholinesterase activity, beta amyloid aggregation, and A beta neurotoxicity
-
Rizzo S, Riviere C, Piazzi L, et al. Benzofuran-based hybrid compound's for the inhibition of cholinesterase activity, beta amyloid aggregation, and A beta neurotoxicity. J Med Chem 2008; 51: 2883-6.
-
(2008)
J Med Chem
, vol.51
, pp. 2883-2886
-
-
Rizzo, S.1
Riviere, C.2
Piazzi, L.3
-
139
-
-
84856813248
-
Dihydroxybenzoic Acid Isomers Differentially Dissociate Soluble Biotinyl-A beta(1-42) Oligomers
-
LeVine H, Lampe L, Abdelmoti L, Augelli-Szafran CE. Dihydroxybenzoic Acid Isomers Differentially Dissociate Soluble Biotinyl-A beta(1-42) Oligomers. Biochemistry 2012; 51: 307-15.
-
(2012)
Biochemistry
, vol.51
, pp. 307-315
-
-
Levine, H.1
Lampe, L.2
Abdelmoti, L.3
Augelli-Szafran, C.E.4
-
140
-
-
0035349804
-
Inhibition of Alzheimer's disease beta-amyloid aggregation, neurotoxicity, and in vivo deposition by nitrophenols: Implications for Alzheimer's therapy
-
De Felice FG, Houzel JC, Garcia-Abreu J, et al. Inhibition of Alzheimer's disease beta-amyloid aggregation, neurotoxicity, and in vivo deposition by nitrophenols: implications for Alzheimer's therapy. Faseb J 2001; 15: 1297-9.
-
(2001)
Faseb J
, vol.15
, pp. 1297-1299
-
-
de Felice, F.G.1
Houzel, J.C.2
Garcia-Abreu, J.3
-
141
-
-
77955865110
-
Clicked Bivalent Ligands Containing Curcumin and Cholesterol As Multifunctional A beta Oligomerization Inhibitors: Design, Synthesis, and Biological Characterization
-
Lenhart JA, Ling XA, Gandhi R, et al. Clicked Bivalent Ligands Containing Curcumin and Cholesterol As Multifunctional A beta Oligomerization Inhibitors: Design, Synthesis, and Biological Characterization. J Med Chem 2010; 53: 6198-209.
-
(2010)
J Med Chem
, vol.53
, pp. 6198-6609
-
-
Lenhart, J.A.1
Ling, X.A.2
Gandhi, R.3
-
142
-
-
0033563079
-
Inhibition of fibril formation in beta-amyloid peptide by a novel series of benzofurans
-
Howlett DR, Perry AE, Godfrey F, et al. Inhibition of fibril formation in beta-amyloid peptide by a novel series of benzofurans. Biochem J 1999; 340: 283-9.
-
(1999)
Biochem J
, vol.340
, pp. 283-289
-
-
Howlett, D.R.1
Perry, A.E.2
Godfrey, F.3
-
143
-
-
0028062189
-
Rifampicin Prevents the Aggregation and Neurotoxicity of Amyloid-Beta Protein in-Vitro
-
Tomiyama T, Asano S, Suwa Y, et al. Rifampicin Prevents the Aggregation and Neurotoxicity of Amyloid-Beta Protein in-Vitro. Biochemical and Biophysical Res Communications 1994; 204: 76-83.
-
(1994)
Biochemical and Biophysical Res Communications
, vol.204
, pp. 76-83
-
-
Tomiyama, T.1
Asano, S.2
Suwa, Y.3
-
144
-
-
33645929400
-
Inhibition of amyloid fibril formation and cytotoxicity by hydroxyindole derivatives
-
Cohen T, Frydman-Marom A, Rechter M, Gazit E. Inhibition of amyloid fibril formation and cytotoxicity by hydroxyindole derivatives. Biochemistry 2006; 45: 4727-35.
-
(2006)
Biochemistry
, vol.45
, pp. 4727-4735
-
-
Cohen, T.1
Frydman-Marom, A.2
Rechter, M.3
Gazit, E.4
-
145
-
-
77955411848
-
Structural optimization and biological evaluation of substituted bisphenol A derivatives as betaamyloid peptide aggregation inhibitors
-
Zhou Y, Jiang C, Zhang Y, et al. Structural optimization and biological evaluation of substituted bisphenol A derivatives as betaamyloid peptide aggregation inhibitors. J Med Chem 2010; 53: 5449-66.
-
(2010)
J Med Chem
, vol.53
, pp. 5449-5466
-
-
Zhou, Y.1
Jiang, C.2
Zhang, Y.3
-
146
-
-
84855759411
-
The iAbeta5p beta-breaker peptide regulates the Abeta(25-35) interaction with lipid bilayers through a cholesterol-mediated mechanism
-
Vitiello G, Grimaldi M, D'Ursi AM, D'Errico G. The iAbeta5p beta-breaker peptide regulates the Abeta(25-35) interaction with lipid bilayers through a cholesterol-mediated mechanism. Biochem Biophys Res Commun 2012; 417: 88-92.
-
(2012)
Biochem Biophys Res Commun
, vol.417
, pp. 88-92
-
-
Vitiello, G.1
Grimaldi, M.2
D'Ursi, A.M.3
D'Errico, G.4
-
147
-
-
84155164900
-
Inhibition of amyloid peptide fragment Abeta25-35 fibrillogenesis and toxicity by Nterminal beta-amino acid-containing esapeptides: Is taurine moiety essential for in vivo effects?
-
Giordano C, Sansone A, Masi A, et al. Inhibition of amyloid peptide fragment Abeta25-35 fibrillogenesis and toxicity by Nterminal beta-amino acid-containing esapeptides: is taurine moiety essential for in vivo effects? Chem Biol Drug Des 2012; 79: 30-7.
-
(2012)
Chem Biol Drug Des
, vol.79
, pp. 30-37
-
-
Giordano, C.1
Sansone, A.2
Masi, A.3
-
148
-
-
80052229078
-
The generic amyloid formation inhibition effect of a designed small aromatic beta-breaking peptide
-
Frydman-Marom A, Shaltiel-Karyo R, Moshe S, Gazit E. The generic amyloid formation inhibition effect of a designed small aromatic beta-breaking peptide. Amyloid 2011; 18: 119-27.
-
(2011)
Amyloid
, vol.18
, pp. 119-127
-
-
Frydman-Marom, A.1
Shaltiel-Karyo, R.2
Moshe, S.3
Gazit, E.4
-
149
-
-
70350131474
-
Reversal of temperature-induced conformational changes in the amyloid-beta peptide, Abeta40, by the beta-sheet breaker peptides 16-23 and 17-24
-
Hatip FF, Suenaga M, Yamada T, Matsunaga Y. Reversal of temperature-induced conformational changes in the amyloid-beta peptide, Abeta40, by the beta-sheet breaker peptides 16-23 and 17-24. Br J Pharmacol 2009; 158: 1165-72.
-
(2009)
Br J Pharmacol
, vol.158
, pp. 1165-1172
-
-
Hatip, F.F.1
Suenaga, M.2
Yamada, T.3
Matsunaga, Y.4
-
150
-
-
63449141261
-
Design and synthesis of new trehalose-conjugated pentapeptides as inhibitors of Abeta(1-42) fibrillogenesis and toxicity
-
De Bona P, Giuffrida ML, Caraci F, et al. Design and synthesis of new trehalose-conjugated pentapeptides as inhibitors of Abeta(1-42) fibrillogenesis and toxicity. J Pept Sci 2009; 15: 220-8.
-
(2009)
J Pept Sci
, vol.15
, pp. 220-228
-
-
de Bona, P.1
Giuffrida, M.L.2
Caraci, F.3
-
151
-
-
77956681609
-
Development of retro-inverso peptides as anti-aggregation drugs for beta-amyloid in Alzheimer's disease
-
Matharu B, El-Agnaf O, Razvi A, Austen BM. Development of retro-inverso peptides as anti-aggregation drugs for beta-amyloid in Alzheimer's disease. Peptides 2010; 31: 1866-72.
-
(2010)
Peptides
, vol.31
, pp. 1866-1872
-
-
Matharu, B.1
El-Agnaf, O.2
Razvi, A.3
Austen, B.M.4
-
152
-
-
0033603003
-
Modifiedpeptide inhibitors of amyloid beta-peptide polymerization
-
Findeis MA, Musso GM, Arico-Muendel CC, et al. Modifiedpeptide inhibitors of amyloid beta-peptide polymerization. Biochemistry 1999; 38: 6791-800.
-
(1999)
Biochemistry
, vol.38
, pp. 6791-6800
-
-
Findeis, M.A.1
Musso, G.M.2
Arico-Muendel, C.C.3
-
153
-
-
33845918172
-
Heat shock proteins 70 and 90 inhibit early stages of amyloid beta-(1-42) aggregation in vitro
-
Evans CG, Wisen S, Gestwicki JE. Heat shock proteins 70 and 90 inhibit early stages of amyloid beta-(1-42) aggregation in vitro. J Biol Chem 2006; 281: 33182-91.
-
(2006)
J Biol Chem
, vol.281
, pp. 33182-33191
-
-
Evans, C.G.1
Wisen, S.2
Gestwicki, J.E.3
-
154
-
-
33750968798
-
Inhibition of beta-amyloid fibrillization by directed evolution of a beta-sheet presenting miniature protein
-
Smith TJ, Stains CI, Meyer SC, Ghosh I. Inhibition of beta-amyloid fibrillization by directed evolution of a beta-sheet presenting miniature protein. J Am Chem Soc 2006; 128: 14456-7.
-
(2006)
J Am Chem Soc
, vol.128
, pp. 14456-14457
-
-
Smith, T.J.1
Stains, C.I.2
Meyer, S.C.3
Ghosh, I.4
-
155
-
-
0042818327
-
Stereoselective interactions of peptide inhibitors with the beta-amyloid peptide
-
Chalifour RJ, McLaughlin RW, Lavoie L, et al. Stereoselective interactions of peptide inhibitors with the beta-amyloid peptide. J Biol Chem 2003; 278: 34874-81.
-
(2003)
J Biol Chem
, vol.278
, pp. 34874-34881
-
-
Chalifour, R.J.1
McLaughlin, R.W.2
Lavoie, L.3
-
156
-
-
9444229933
-
Inhibition of amyloid fibrillogenesis and toxicity by a peptide chaperone
-
Santhoshkumar P, Sharma KK. Inhibition of amyloid fibrillogenesis and toxicity by a peptide chaperone. Mol Cell Biochem 2004; 267: 147-55.
-
(2004)
Mol Cell Biochem
, vol.267
, pp. 147-155
-
-
Santhoshkumar, P.1
Sharma, K.K.2
-
157
-
-
46749123000
-
C4b-binding protein in Alzheimer's disease: Binding to Abeta1-42 and to dead cells
-
Trouw LA, Nielsen HM, Minthon L, et al. C4b-binding protein in Alzheimer's disease: binding to Abeta1-42 and to dead cells. Mol Immunol 2008; 45: 3649-60.
-
(2008)
Mol Immunol
, vol.45
, pp. 3649-3660
-
-
Trouw, L.A.1
Nielsen, H.M.2
Minthon, L.3
-
158
-
-
84859723641
-
A multimodal RAGE-specific inhibitor reduces amyloid beta-mediated brain disorder in a mouse model of Alzheimer disease
-
Deane R, Singh I, Sagare AP, et al. A multimodal RAGE-specific inhibitor reduces amyloid beta-mediated brain disorder in a mouse model of Alzheimer disease. J Clin Invest 2012; 122: 1377-92.
-
(2012)
J Clin Invest
, vol.122
, pp. 1377-1392
-
-
Deane, R.1
Singh, I.2
Sagare, A.P.3
-
159
-
-
0035964269
-
Subsite specificity of memapsin 2 (beta-secretase): Implications for inhibitor design
-
Turner RT, 3rd, Koelsch G, Hong L, et al. Subsite specificity of memapsin 2 (beta-secretase): implications for inhibitor design. Biochemistry 2001; 40: 10001-6.
-
(2001)
Biochemistry
, vol.40
, pp. 10001-10006
-
-
Turner III, R.T.1
Koelsch, G.2
Hong, L.3
-
160
-
-
80052821752
-
The cysteine protease inhibitor, E64d, reduces brain amyloid-beta and improves memory deficits in Alzheimer's disease animal models by inhibiting cathepsin B, but not BACE1, beta-secretase activity
-
Hook G, Hook V, Kindy M. The cysteine protease inhibitor, E64d, reduces brain amyloid-beta and improves memory deficits in Alzheimer's disease animal models by inhibiting cathepsin B, but not BACE1, beta-secretase activity. J Alzheimers Dis 2011; 26: 387-408.
-
(2011)
J Alzheimers Dis
, vol.26
, pp. 387-408
-
-
Hook, G.1
Hook, V.2
Kindy, M.3
|