-
1
-
-
0344944630
-
Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution
-
Stefani M & Dobson CM (2003) Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution. J Mol Med 81, 678-699.
-
(2003)
J Mol Med
, vol.81
, pp. 678-699
-
-
Stefani, M.1
Dobson, C.M.2
-
2
-
-
33746377894
-
Protein misfolding, functional amyloid, and human disease
-
Chiti F & Dobson CM (2006) Protein misfolding, functional amyloid, and human disease. Annu Rev Biochem 75, 333-366.
-
(2006)
Annu Rev Biochem
, vol.75
, pp. 333-366
-
-
Chiti, F.1
Dobson, C.M.2
-
3
-
-
10644225416
-
Protein misfolding and aggregation: new examples in medicine and biology of the dark side of the protein world
-
Stefani M (2004) Protein misfolding and aggregation: new examples in medicine and biology of the dark side of the protein world. Biochim Biophys Acta 1739, 5-25.
-
(2004)
Biochim Biophys Acta
, pp. 5-25
-
-
Stefani, M.1
-
4
-
-
20444403757
-
Prediction of "aggregation-prone" and "aggregation-susceptible" regions in proteins associated with neurodegenerative diseases
-
Pawar AP, Dubay KF, Zurdo J, Chiti F, Vendruscolo M & Dobson CM (2005) Prediction of "aggregation-prone" and "aggregation-susceptible" regions in proteins associated with neurodegenerative diseases. J Mol Biol 350, 379-392.
-
(2005)
J Mol Biol
, vol.350
, pp. 379-392
-
-
Pawar, A.P.1
Dubay, K.F.2
Zurdo, J.3
Chiti, F.4
Vendruscolo, M.5
Dobson, C.M.6
-
5
-
-
0035849879
-
Cause of neuronal death in neurodegenerative diseases attributable to expansion of glutamine repeats
-
Perutz MF & Windle AH (2001) Cause of neuronal death in neurodegenerative diseases attributable to expansion of glutamine repeats. Nature 412, 143-144.
-
(2001)
Nature
, vol.412
, pp. 143-144
-
-
Perutz, M.F.1
Windle, A.H.2
-
6
-
-
0026597063
-
Alzheimer's disease: the amyloid cascade hypothesis
-
Hardy JA & Higgins CA (1992) Alzheimer's disease: the amyloid cascade hypothesis. Science 256, 184-185.
-
(1992)
Science
, vol.256
, pp. 184-185
-
-
Hardy, J.A.1
Higgins, C.A.2
-
7
-
-
0032006678
-
Alternative conformation of amyloidogenic proteins and their multi-step assembly pathways
-
Kelly J (1998) Alternative conformation of amyloidogenic proteins and their multi-step assembly pathways. Curr Opin Struct Biol 8, 101-106.
-
(1998)
Curr Opin Struct Biol
, vol.8
, pp. 101-106
-
-
Kelly, J.1
-
8
-
-
0035961329
-
The structural basis of protein folding and its links with human disease
-
Dobson CM (2001) The structural basis of protein folding and its links with human disease. Philos Trans R Soc Lond B Biol Sci 356, 133-145.
-
(2001)
Philos Trans R Soc Lond B Biol Sci
, vol.356
, pp. 133-145
-
-
Dobson, C.M.1
-
9
-
-
34547631623
-
Prevention of amyloid-like aggregation as a driving force of protein evolution
-
Monsellier E & Chiti F (2007) Prevention of amyloid-like aggregation as a driving force of protein evolution. EMBO Rep 8, 737-742.
-
(2007)
EMBO Rep
, vol.8
, pp. 737-742
-
-
Monsellier, E.1
Chiti, F.2
-
10
-
-
0035139109
-
Cellular defences against unfolded proteins: a cell biologist thinks about neurodegenerative diseases
-
Sherman MY & Goldberg AL (2001) Cellular defences against unfolded proteins: a cell biologist thinks about neurodegenerative diseases. Neuron 29, 15-32.
-
(2001)
Neuron
, vol.29
, pp. 15-32
-
-
Sherman, M.Y.1
Goldberg, A.L.2
-
11
-
-
0029078972
-
Correlation of synaptic and pathological markers with cognition of the elderly
-
Dickson DW (1995) Correlation of synaptic and pathological markers with cognition of the elderly. Neurobiol Aging 16, 285-298.
-
(1995)
Neurobiol Aging
, vol.16
, pp. 285-298
-
-
Dickson, D.W.1
-
12
-
-
33846023647
-
Lysozyme amyloid oligomers and fibrils induce cellular death via different apoptotic/necrotic pathways
-
Gharibyan AL, Zamotin V, Yanamandra K, Moskaleva OS, Margulis BA, Kostanyan IA & Morozova-Roche LA (2007) Lysozyme amyloid oligomers and fibrils induce cellular death via different apoptotic/necrotic pathways. J Mol Biol 365, 1337-1349.
-
(2007)
J Mol Biol
, vol.365
, pp. 1337-1349
-
-
Gharibyan, A.L.1
Zamotin, V.2
Yanamandra, K.3
Moskaleva, O.S.4
Margulis, B.A.5
Kostanyan, I.A.6
Morozova-Roche, L.A.7
-
13
-
-
33744961169
-
Amyloid fibrils of mammalian prion protein are highly toxic to cultured cells and primary neurons
-
Novitskaya V, Bocharova OV, Bronstein I & Baskakov IV (2006) Amyloid fibrils of mammalian prion protein are highly toxic to cultured cells and primary neurons. J Biol Chem 281, 13828-13836.
-
(2006)
J Biol Chem
, vol.281
, pp. 13828-13836
-
-
Novitskaya, V.1
Bocharova, O.V.2
Bronstein, I.3
Baskakov, I.V.4
-
14
-
-
0037041426
-
Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation invivo
-
Walsh DM, Klyubin I, Fadeeva JV, Cullen WK, Anwyl R, Wolfe MS, Rowan MJ & Selkoe DJ (2002) Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation invivo. Nature 416, 535-539.
-
(2002)
Nature
, vol.416
, pp. 535-539
-
-
Walsh, D.M.1
Klyubin, I.2
Fadeeva, J.V.3
Cullen, W.K.4
Anwyl, R.5
Wolfe, M.S.6
Rowan, M.J.7
Selkoe, D.J.8
-
15
-
-
0034681163
-
Acceleration of oligomerization not fibrillization is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease. Implication for pathogenesis and therapy
-
Conway KA, Lee S-J, Rochet JC, Ding TT, Williamson RE & Lansbury PT (2000) Acceleration of oligomerization not fibrillization is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease. Implication for pathogenesis and therapy. Proc Natl Acad Sci USA 97, 571-576.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 571-576
-
-
Conway, K.A.1
Lee, S.2
Rochet, J.C.3
Ding, T.T.4
Williamson, R.E.5
Lansbury, P.T.6
-
16
-
-
1542357685
-
Tissue damage in the amyloidoses: transthyretin monomers and nonnative oligomers are the major cytotoxic species in tissue culture
-
Reixach N, Deechingkit S, Jiang X, Kelly JW & Buxbaum JN (2004) Tissue damage in the amyloidoses: transthyretin monomers and nonnative oligomers are the major cytotoxic species in tissue culture. Proc Natl Acad Sci USA 101, 2817-2822.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 2817-2822
-
-
Reixach, N.1
Deechingkit, S.2
Jiang, X.3
Kelly, J.W.4
Buxbaum, J.N.5
-
17
-
-
0037041420
-
Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases
-
Bucciantini M, Giannoni E, Chiti F, Baroni F, Formigli L, Zurdo J, Taddei N, Ramponi G, Dobson CM & Stefani M (2002) Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases. Nature 416, 507-511.
-
(2002)
Nature
, vol.416
, pp. 507-511
-
-
Bucciantini, M.1
Giannoni, E.2
Chiti, F.3
Baroni, F.4
Formigli, L.5
Zurdo, J.6
Taddei, N.7
Ramponi, G.8
Dobson, C.M.9
Stefani, M.10
-
18
-
-
0242668337
-
Common structure of soluble amyloid oligomers implies common mechanisms of pathogenesis
-
Kayed R, Head E, Thompson JL, McIntire TM, Milton SC, Cotman CW & Glabe CG (2003) Common structure of soluble amyloid oligomers implies common mechanisms of pathogenesis. Science 300, 486-489.
-
(2003)
Science
, vol.300
, pp. 486-489
-
-
Kayed, R.1
Head, E.2
Thompson, J.L.3
McIntire, T.M.4
Milton, S.C.5
Cotman, C.W.6
Glabe, C.G.7
-
19
-
-
0036850023
-
Neuroinflammation in Alzheimer's disease and prion disease
-
Eikelemboom R, Bate C, Van Gool WA, Hoozemans JJ, Rozemuller JM, Veerhuis R & Williams A (2002) Neuroinflammation in Alzheimer's disease and prion disease. Glia 40, 232-239.
-
(2002)
Glia
, vol.40
, pp. 232-239
-
-
Eikelemboom, R.1
Bate, C.2
Van Gool, W.A.3
Hoozemans, J.J.4
Rozemuller, J.M.5
Veerhuis, R.6
Williams, A.7
-
20
-
-
35848951621
-
Abeta 1-42 induces mild endoplasmic reticulum stress in an aggregation state-dependent manner
-
Chafekar FM, Hoozemans JJ, Zwart R, Baas F & Scheper W (2007) Abeta 1-42 induces mild endoplasmic reticulum stress in an aggregation state-dependent manner. Antioxid Redox Signal 9, 2245-2254.
-
(2007)
Antioxid Redox Signal
, vol.9
, pp. 2245-2254
-
-
Chafekar, F.M.1
Hoozemans, J.J.2
Zwart, R.3
Baas, F.4
Scheper, W.5
-
21
-
-
50949097728
-
Oligomer-specific Aβ toxicity in cell models is mediated by selective uptake
-
Chafekar SM, Baas F & Scheper W (2008) Oligomer-specific Aβ toxicity in cell models is mediated by selective uptake. Biochim Biophys Acta 1782, 523-531.
-
(2008)
Biochim Biophys Acta
, pp. 523-531
-
-
Chafekar, S.M.1
Baas, F.2
Scheper, W.3
-
22
-
-
0037551741
-
Protofibrils, pores, fibrils and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders
-
Caughey B & Lansbury PT (2003) Protofibrils, pores, fibrils and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders. Annu Rev Neurosci 26, 267-298.
-
(2003)
Annu Rev Neurosci
, vol.26
, pp. 267-298
-
-
Caughey, B.1
Lansbury, P.T.2
-
23
-
-
1842529223
-
Fibrillogenesis and cytotoxic activity of the amyloid-forming apomyoglobin mutant W7FW14F
-
Sirangelo I, Malmo C, Iannuzzi C, Mezzogiorno A, Bianco MR, Papa M & Irace G (2004) Fibrillogenesis and cytotoxic activity of the amyloid-forming apomyoglobin mutant W7FW14F. J Biol Chem 279, 13183-13189.
-
(2004)
J Biol Chem
, vol.279
, pp. 13183-13189
-
-
Sirangelo, I.1
Malmo, C.2
Iannuzzi, C.3
Mezzogiorno, A.4
Bianco, M.R.5
Papa, M.6
Irace, G.7
-
24
-
-
14644442872
-
Intraneuronal Aβ causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice
-
Billings LM, Oddo S, Green KN, McGaugh JL & LaFerla FM (2005) Intraneuronal Aβ causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice. Neuron 45, 675-688.
-
(2005)
Neuron
, vol.45
, pp. 675-688
-
-
Billings, L.M.1
Oddo, S.2
Green, K.N.3
McGaugh, J.L.4
LaFerla, F.M.5
-
25
-
-
62649174753
-
Oligomeric amyloid beta associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques
-
Koffie RM, Meyer-Luehmann M, Hashimoto T, Adams KW, Mielke ML, Garcia-Alloza M, Micheva KD, Smith SJ, Kim ML, Lee VM et al. (2009) Oligomeric amyloid beta associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques. Proc Natl Acad Sci USA 106, 4012-4017.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 4012-4017
-
-
Koffie, R.M.1
Meyer-Luehmann, M.2
Hashimoto, T.3
Adams, K.W.4
Mielke, M.L.5
Garcia-Alloza, M.6
Micheva, K.D.7
Smith, S.J.8
Kim, M.L.9
Lee, V.M.10
-
26
-
-
76149102617
-
Evidence for proteotoxicity in β cells in type 2 diabetes, toxic islet amyloid polypeptide oligomers form intracellularly in the secretory pathway
-
Gurlo T, Ryazantsev S, Huang C-J, Yeh MW, Reber HA, Hines OJ, O'Brien TD, Glabe CG & Butler PC (2009) Evidence for proteotoxicity in β cells in type 2 diabetes, toxic islet amyloid polypeptide oligomers form intracellularly in the secretory pathway. Am J Pathol 176, 861-869.
-
(2009)
Am J Pathol
, vol.176
, pp. 861-869
-
-
Gurlo, T.1
Ryazantsev, S.2
Huang, C.3
Yeh, M.W.4
Reber, H.A.5
Hines, O.J.6
O'Brien, T.D.7
Glabe, C.G.8
Butler, P.C.9
-
27
-
-
0037047118
-
The protofilament structure of insulin amyloid fibrils
-
Jiménez JL, Nettleton EJ, Bouchard M, Robinson CV, Dobson CM & Saibil HR (2002) The protofilament structure of insulin amyloid fibrils. Proc Natl Acad Sci USA 99, 9196-9201.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 9196-9201
-
-
Jiménez, J.L.1
Nettleton, E.J.2
Bouchard, M.3
Robinson, C.V.4
Dobson, C.M.5
Saibil, H.R.6
-
28
-
-
28444442999
-
3D structure of Alzheimer's amyloid-β(1-42) fibrils
-
Lührs T, Ritter C, Adrian M, Riek-Loher D, Bohrmann B, Döbeli H, Schubert D & Riek R (2005) 3D structure of Alzheimer's amyloid-β(1-42) fibrils. Proc Natl Acad Sci USA 102, 17342-17347.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 17342-17347
-
-
Lührs, T.1
Ritter, C.2
Adrian, M.3
Riek-Loher, D.4
Bohrmann, B.5
Döbeli, H.6
Schubert, D.7
Riek, R.8
-
29
-
-
12244249201
-
Self-propagating, molecular-level polymorphism in Alzheimer's β-amyloid fibrils
-
Petkova AT, Leapman RD, Guo Z, Yau W-M, Mattson MP & Tycko R (2005) Self-propagating, molecular-level polymorphism in Alzheimer's β-amyloid fibrils. Science 307, 262-265.
-
(2005)
Science
, vol.307
, pp. 262-265
-
-
Petkova, A.T.1
Leapman, R.D.2
Guo, Z.3
Yau, W.4
Mattson, M.P.5
Tycko, R.6
-
30
-
-
66149140617
-
Seeded growth of β-amyloid fibrils from Alzheimer's brain-derived fibrils produces a distinct fibril structure
-
Paravastu AK, Qawash I, Leapman RD, Meredith SC & Tycko R (2009) Seeded growth of β-amyloid fibrils from Alzheimer's brain-derived fibrils produces a distinct fibril structure. Proc Natl Acad Sci USA 105, 7443-7448.
-
(2009)
Proc Natl Acad Sci USA
, vol.105
, pp. 7443-7448
-
-
Paravastu, A.K.1
Qawash, I.2
Leapman, R.D.3
Meredith, S.C.4
Tycko, R.5
-
31
-
-
70450224432
-
Role of small oligomers on the amyloidogenic aggregation free-energy landscape
-
He X, Giurleo JT & Talaga DS (2010) Role of small oligomers on the amyloidogenic aggregation free-energy landscape. J Mol Biol 395, 134-154.
-
(2010)
J Mol Biol
, vol.395
, pp. 134-154
-
-
He, X.1
Giurleo, J.T.2
Talaga, D.S.3
-
32
-
-
11144353842
-
Monitoring the process of HypF fibrillization and liposome permeabilization by protofibrils
-
Relini A, Torrassa S, Rolandi R, Gliozzi A, Rosano C, Canale C, Bolognesi M, Plakoutsi G, Bucciantini M, Chiti F et al. (2004) Monitoring the process of HypF fibrillization and liposome permeabilization by protofibrils. J Mol Biol 338, 943-957.
-
(2004)
J Mol Biol
, vol.338
, pp. 943-957
-
-
Relini, A.1
Torrassa, S.2
Rolandi, R.3
Gliozzi, A.4
Rosano, C.5
Canale, C.6
Bolognesi, M.7
Plakoutsi, G.8
Bucciantini, M.9
Chiti, F.10
-
33
-
-
0037174879
-
Huntingtin spheroids and protofibrils as precursors in polyglutamine fibrillization
-
Poirier MA, Li H, Macosko J, Cail S, Amzel M & Ross CA (2002) Huntingtin spheroids and protofibrils as precursors in polyglutamine fibrillization. J Biol Chem 277, 41032-41037.
-
(2002)
J Biol Chem
, vol.277
, pp. 41032-41037
-
-
Poirier, M.A.1
Li, H.2
Macosko, J.3
Cail, S.4
Amzel, M.5
Ross, C.A.6
-
34
-
-
33644527256
-
Characterization of oligomers during alpha-synuclein aggregation using intrinsic tryptophan fluorescence
-
Dusa A, Kaylor J, Edridge S, Bodner N, Hong DP & Fink AL (2006) Characterization of oligomers during alpha-synuclein aggregation using intrinsic tryptophan fluorescence. Biochemistry 45, 2752-2760.
-
(2006)
Biochemistry
, vol.45
, pp. 2752-2760
-
-
Dusa, A.1
Kaylor, J.2
Edridge, S.3
Bodner, N.4
Hong, D.P.5
Fink, A.L.6
-
35
-
-
34848929022
-
Structural reorganisation and potential toxicity of oligomeric species formed during the assembly of amyloid fibrils
-
Cheon M, Chang I, Mohanty S, Luheshi LM, Dobson CM, Vendruscolo M & Favin G (2007) Structural reorganisation and potential toxicity of oligomeric species formed during the assembly of amyloid fibrils. Plos Comput Biol 3, 1727-1738.
-
(2007)
Plos Comput Biol
, vol.3
, pp. 1727-1738
-
-
Cheon, M.1
Chang, I.2
Mohanty, S.3
Luheshi, L.M.4
Dobson, C.M.5
Vendruscolo, M.6
Favin, G.7
-
36
-
-
0034714351
-
Nucleated conformation conversion and the replication of conformational information by a prion determinant
-
Serio TR, Cashikar AG, Kowal AS, Sawicki GJ, Moslehi JJ, Serpell L, Arnsdorf MF & Lindquist S (2000) Nucleated conformation conversion and the replication of conformational information by a prion determinant. Science 289, 1317-1321.
-
(2000)
Science
, vol.289
, pp. 1317-1321
-
-
Serio, T.R.1
Cashikar, A.G.2
Kowal, A.S.3
Sawicki, G.J.4
Moslehi, J.J.5
Serpell, L.6
Arnsdorf, M.F.7
Lindquist, S.8
-
37
-
-
23444447864
-
Evidence for a mechanism for amyloid formation involving reorganization within native-like precursor aggregates
-
Plakoutsi G, Bemporad F, Calamai M, Taddei N, Dobson CM & Chiti F (2005) Evidence for a mechanism for amyloid formation involving reorganization within native-like precursor aggregates. J Mol Biol 351, 910-922.
-
(2005)
J Mol Biol
, vol.351
, pp. 910-922
-
-
Plakoutsi, G.1
Bemporad, F.2
Calamai, M.3
Taddei, N.4
Dobson, C.M.5
Chiti, F.6
-
38
-
-
30344457011
-
Probing the mechanism of amyloidogenesis through a tandem repeat of the pi3-sh3 domain suggests a generic model for protein aggregation and fibril formation
-
Bader R, Bamford R, Zurdo J, Luisi BF & Dobson CM (2006) Probing the mechanism of amyloidogenesis through a tandem repeat of the pi3-sh3 domain suggests a generic model for protein aggregation and fibril formation. J Mol Biol 356, 189-208.
-
(2006)
J Mol Biol
, vol.356
, pp. 189-208
-
-
Bader, R.1
Bamford, R.2
Zurdo, J.3
Luisi, B.F.4
Dobson, C.M.5
-
39
-
-
57749098600
-
Amyloid formation by globular proteins under native conditions
-
Chiti F & Dobson CM (2009) Amyloid formation by globular proteins under native conditions. Nat Chem Biol 5, 15-22.
-
(2009)
Nat Chem Biol
, vol.5
, pp. 15-22
-
-
Chiti, F.1
Dobson, C.M.2
-
40
-
-
28444454101
-
Amyloid fibril formation can proceed from different conformations of a partially unfolded protein
-
Calamai M, Chiti F & Dobson CM (2005) Amyloid fibril formation can proceed from different conformations of a partially unfolded protein. Biophys J 89, 4201-4210.
-
(2005)
Biophys J
, vol.89
, pp. 4201-4210
-
-
Calamai, M.1
Chiti, F.2
Dobson, C.M.3
-
41
-
-
3943084181
-
Emerging principles of conformation-based prion inheritance
-
Chien P, Weissman JS & DePace AH (2004) Emerging principles of conformation-based prion inheritance. Annu Rev Biochem 73, 617-656.
-
(2004)
Annu Rev Biochem
, vol.73
, pp. 617-656
-
-
Chien, P.1
Weissman, J.S.2
DePace, A.H.3
-
42
-
-
34249290108
-
Atomic structures of amyloid cross-β spines reveal varied steric zippers
-
Sawaya MR, Sambashivan S, Nelson R, Ivanova MI, Sievers SA, Apostol MI, Thompson MJ, Balbirnie M, Wiltzius JJW, McFarlane HT et al. (2007) Atomic structures of amyloid cross-β spines reveal varied steric zippers. Nature 447, 453-457.
-
(2007)
Nature
, vol.447
, pp. 453-457
-
-
Sawaya, M.R.1
Sambashivan, S.2
Nelson, R.3
Ivanova, M.I.4
Sievers, S.A.5
Apostol, M.I.6
Thompson, M.J.7
Balbirnie, M.8
Wiltzius, J.J.W.9
McFarlane, H.T.10
-
43
-
-
75349097530
-
The causative link between the structure of aberrant protein oligomers and their ability to cause cell dysfunction
-
Campioni S, Mannini B, Pensalfini A, Zampagni M, Parrini C, Evangelisti E, Relini A, Stefani M, Dobson CM, Cecchi C & Chiti F (2010) The causative link between the structure of aberrant protein oligomers and their ability to cause cell dysfunction. Nat Chem Biol, 6, 140-147.
-
(2010)
Nat Chem Biol
, vol.6
, pp. 140-147
-
-
Campioni, S.1
Mannini, B.2
Pensalfini, A.3
Zampagni, M.4
Parrini, C.5
Evangelisti, E.6
Relini, A.7
Stefani, M.8
Dobson, C.M.9
Cecchi, C.10
Chiti, F.11
-
44
-
-
17044381327
-
Fibril conformation as the basis of species- and strain-dependent seeding specificity of mammalian prion amyloids
-
Jones EM & Surewicz WK (2005) Fibril conformation as the basis of species- and strain-dependent seeding specificity of mammalian prion amyloids. Cell 121, 63-72.
-
(2005)
Cell
, vol.121
, pp. 63-72
-
-
Jones, E.M.1
Surewicz, W.K.2
-
45
-
-
33745268224
-
Different conformations of amyloid β induce neurotoxicity by distinct mechanisms in human cortical neurons
-
Deshpande A, Mina E, Glabe C & Busciglio J (2006) Different conformations of amyloid β induce neurotoxicity by distinct mechanisms in human cortical neurons. J Neurosci 26, 6011-6018.
-
(2006)
J Neurosci
, vol.26
, pp. 6011-6018
-
-
Deshpande, A.1
Mina, E.2
Glabe, C.3
Busciglio, J.4
-
46
-
-
45949102576
-
Aβ42 mutants with different aggregation profiles induce distinct pathologies in Drosophila
-
Iijima K, Chiang H-C, Hearn SA, Hakker I, Gatt A, Shenton C, Granger L, Leung A, Iijima-Ando K & Zhong Y (2008) Aβ42 mutants with different aggregation profiles induce distinct pathologies in Drosophila. PLoS ONE 3, 1-8.
-
(2008)
PLoS ONE
, vol.3
, pp. 1-8
-
-
Iijima, K.1
Chiang, H.2
Hearn, S.A.3
Hakker, I.4
Gatt, A.5
Shenton, C.6
Granger, L.7
Leung, A.8
Iijima-Ando, K.9
Zhong, Y.10
-
47
-
-
33749020837
-
Exogeneous induction of cerebral β-amyloidogenesis is governed by agent and host
-
Meyer-Luheman M, Coomaraswamy J, Bolmont T, Kaeser S, Schaefer C, Kilger E, Neuenschwander A, Abramowski D, Frey P, Jaton AJ et al. (2006) Exogeneous induction of cerebral β-amyloidogenesis is governed by agent and host. Science 313, 1781-1784.
-
(2006)
Science
, vol.313
, pp. 1781-1784
-
-
Meyer-Luheman, M.1
Coomaraswamy, J.2
Bolmont, T.3
Kaeser, S.4
Schaefer, C.5
Kilger, E.6
Neuenschwander, A.7
Abramowski, D.8
Frey, P.9
Jaton, A.J.10
-
49
-
-
36249023636
-
Pore-forming proteins share structural and functional homology with amyloid oligomers
-
Yoshiike Y, Kayed R, Milton SC, Takashima A & Glabe CG (2007) Pore-forming proteins share structural and functional homology with amyloid oligomers. Neuromolecular Med 9, 270-275.
-
(2007)
Neuromolecular Med
, vol.9
, pp. 270-275
-
-
Yoshiike, Y.1
Kayed, R.2
Milton, S.C.3
Takashima, A.4
Glabe, C.G.5
-
50
-
-
36749078121
-
Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers
-
Kayed R, Head E, Sarsoza F, Saing T, Cotman CW, Necula M, Margol L, Wu J, Breydo L, Thompson JL et al. (2007) Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers. Mol Neurodegener 2, 1-18.
-
(2007)
Mol Neurodegener
, vol.2
, pp. 1-18
-
-
Kayed, R.1
Head, E.2
Sarsoza, F.3
Saing, T.4
Cotman, C.W.5
Necula, M.6
Margol, L.7
Wu, J.8
Breydo, L.9
Thompson, J.L.10
-
51
-
-
67650079178
-
Structurally distinct amyloid protofibrils form on separate pathways of aggregation of a small protein
-
Kumar S & Udgaonkar JB (2009) Structurally distinct amyloid protofibrils form on separate pathways of aggregation of a small protein. Biochemistry 48, 6441-6449.
-
(2009)
Biochemistry
, vol.48
, pp. 6441-6449
-
-
Kumar, S.1
Udgaonkar, J.B.2
-
52
-
-
33749507375
-
Conformation-dependent anti-amyloid oligomer antibodies
-
Kayed R & Glabe CG (2006) Conformation-dependent anti-amyloid oligomer antibodies. Methods Enzymol 413, 326-344.
-
(2006)
Methods Enzymol
, vol.413
, pp. 326-344
-
-
Kayed, R.1
Glabe, C.G.2
-
53
-
-
68549141378
-
Methods for structural characterization of prefibrillar intermediates and amyloid fibrils
-
Langkilde AE & Vestergaard B (2009) Methods for structural characterization of prefibrillar intermediates and amyloid fibrils. FEBS Lett 583, 2600-2609.
-
(2009)
FEBS Lett
, vol.583
, pp. 2600-2609
-
-
Langkilde, A.E.1
Vestergaard, B.2
-
54
-
-
69449099387
-
17-42 (p3) oligomers: the importance of the turn location and its conformation
-
17-42 (p3) oligomers: the importance of the turn location and its conformation. Biophys J 97, 1168-1177.
-
(2009)
Biophys J
, vol.97
, pp. 1168-1177
-
-
Miller, Y.1
Ma, B.2
Nussimov, R.3
-
55
-
-
70349295278
-
Structure-neurotoxicity relationships of amyloid β-protein oligomers
-
Ono K, Condron MM & Teplow DB (2009) Structure-neurotoxicity relationships of amyloid β-protein oligomers. Proc Natl Acad Sci USA 106, 14745-14750.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 14745-14750
-
-
Ono, K.1
Condron, M.M.2
Teplow, D.B.3
-
56
-
-
33748689799
-
Simulations as analytical tools to understand protein aggregation and predict amyloid conformation
-
Ma BY & Nussimov R (2006) Simulations as analytical tools to understand protein aggregation and predict amyloid conformation. Curr Opin Struct Biol 10, 445-452.
-
(2006)
Curr Opin Struct Biol
, vol.10
, pp. 445-452
-
-
Ma, B.Y.1
Nussimov, R.2
-
57
-
-
0035253217
-
Macromolecular crowding: an important but neglected aspect of the intracellular environment
-
Ellis RJ (2001) Macromolecular crowding: an important but neglected aspect of the intracellular environment. Curr Opin Struct Biol 11, 114-119.
-
(2001)
Curr Opin Struct Biol
, vol.11
, pp. 114-119
-
-
Ellis, R.J.1
-
58
-
-
0347753786
-
Two types of Alzheimer's β-amyloid (1-40) peptide membrane interactions: aggregation preventing transmembrane anchoring versus accelerated surface fibril formation
-
Bokvist M, Lindström F, Watts A & Gröbner G (2004) Two types of Alzheimer's β-amyloid (1-40) peptide membrane interactions: aggregation preventing transmembrane anchoring versus accelerated surface fibril formation. J Mol Biol 335, 1039-1049.
-
(2004)
J Mol Biol
, vol.335
, pp. 1039-1049
-
-
Bokvist, M.1
Lindström, F.2
Watts, A.3
Gröbner, G.4
-
59
-
-
33745224979
-
Collagen plays an active role in the aggregation of beta2-microglobulin under physiopathological conditions of dialysis-related amyloidosis
-
Relini A, Canale C, De Stefano S, Rolandi R, Giorgetti S, Stoppini M, Rossi A, Fogolari F, Corazza A, Esposito G et al. (2006) Collagen plays an active role in the aggregation of beta2-microglobulin under physiopathological conditions of dialysis-related amyloidosis. J Biol Chem 281, 16521-16529.
-
(2006)
J Biol Chem
, vol.281
, pp. 16521-16529
-
-
Relini, A.1
Canale, C.2
De Stefano, S.3
Rolandi, R.4
Giorgetti, S.5
Stoppini, M.6
Rossi, A.7
Fogolari, F.8
Corazza, A.9
Esposito, G.10
-
60
-
-
33144470924
-
Heparin accelerates gelsolin amyloidogenesis
-
Suk JY, Zhang F, Balch WE, Linhardt RJ & Kelly JW (2006) Heparin accelerates gelsolin amyloidogenesis. Biochemistry 45, 2234-2242.
-
(2006)
Biochemistry
, vol.45
, pp. 2234-2242
-
-
Suk, J.Y.1
Zhang, F.2
Balch, W.E.3
Linhardt, R.J.4
Kelly, J.W.5
-
61
-
-
57749091860
-
1-42 peptide into stable fibrils of reduced cytotoxicity
-
1-42 peptide into stable fibrils of reduced cytotoxicity. J Biol Chem 283, 32471-32783.
-
(2008)
J Biol Chem
, vol.283
, pp. 32471-32783
-
-
Bravo, R.1
Arimon, M.2
Valle-Delgado, J.J.3
Garcia, R.4
Durany, N.5
Castel, S.6
Cruz, M.7
Ventura, S.8
Fernandez-Busquets, X.9
-
62
-
-
8544264563
-
Double-stranded DNA stimulates the fibrillation of alpha-synuclein invitro and is associated with the mature fibrils: an electron microscopy study
-
Cherny D, Hoyer W, Subramaniam V & Jovin TM (2004) Double-stranded DNA stimulates the fibrillation of alpha-synuclein invitro and is associated with the mature fibrils: an electron microscopy study. J Mol Biol 344, 929-938.
-
(2004)
J Mol Biol
, vol.344
, pp. 929-938
-
-
Cherny, D.1
Hoyer, W.2
Subramaniam, V.3
Jovin, T.M.4
-
63
-
-
34548726211
-
Generic cell dysfunction in neurodegenerative disorders: role of surfaces in early protein misfolding, aggregation, and aggregate cytotoxicity
-
Stefani M (2007) Generic cell dysfunction in neurodegenerative disorders: role of surfaces in early protein misfolding, aggregation, and aggregate cytotoxicity. Neuroscientist 13, 519-531.
-
(2007)
Neuroscientist
, vol.13
, pp. 519-531
-
-
Stefani, M.1
-
64
-
-
21244462685
-
Protein structural perturbation and aggregation on homogeneous surfaces
-
Sethuraman A & Belfort G (2005) Protein structural perturbation and aggregation on homogeneous surfaces. Biophys J 88, 1322-1333.
-
(2005)
Biophys J
, vol.88
, pp. 1322-1333
-
-
Sethuraman, A.1
Belfort, G.2
-
65
-
-
0141653970
-
The human islet amyloid polypeptide forms transient membrane-active prefibrillar assemblies
-
Porat Y, Kolusheva S, Jelinek R & Gazit E (2003) The human islet amyloid polypeptide forms transient membrane-active prefibrillar assemblies. Biochemistry 42, 10971-10977.
-
(2003)
Biochemistry
, vol.42
, pp. 10971-10977
-
-
Porat, Y.1
Kolusheva, S.2
Jelinek, R.3
Gazit, E.4
-
66
-
-
33744961740
-
The yeast prion Ure2p native-like assemblies are toxic to mammalian cells regardless of their aggregation state
-
Pieri L, Bucciantini M, Nosi D, Formigli L, Savistchenko J, Melki R & Stefani M (2006) The yeast prion Ure2p native-like assemblies are toxic to mammalian cells regardless of their aggregation state. J Biol Chem 281, 15337-15344.
-
(2006)
J Biol Chem
, vol.281
, pp. 15337-15344
-
-
Pieri, L.1
Bucciantini, M.2
Nosi, D.3
Formigli, L.4
Savistchenko, J.5
Melki, R.6
Stefani, M.7
-
67
-
-
14344250143
-
Binding of endostatin to phosphatidylserine-containing membranes and formation of amyloid-like fibrils
-
Zhao H, Jutila A, Nurminen T, Wickstrom S, Keski-Oja J & Kinnunen PJ (2005) Binding of endostatin to phosphatidylserine-containing membranes and formation of amyloid-like fibrils. Biochemistry 44, 2857-2863.
-
(2005)
Biochemistry
, vol.44
, pp. 2857-2863
-
-
Zhao, H.1
Jutila, A.2
Nurminen, T.3
Wickstrom, S.4
Keski-Oja, J.5
Kinnunen, P.J.6
-
68
-
-
4043100348
-
Formation of amyloid fibers triggered by phosphatidylserine-containing membranes
-
Zhao H, Tuominen EKJ & Kinnunen PKJ (2004) Formation of amyloid fibers triggered by phosphatidylserine-containing membranes. Biochemistry 43, 10302-10307.
-
(2004)
Biochemistry
, vol.43
, pp. 10302-10307
-
-
Zhao, H.1
Tuominen, E.K.J.2
Kinnunen, P.K.J.3
-
69
-
-
58149220667
-
Cholesterol in Alzheimer's disease: unresolved questions
-
Stefani M & Liguri G (2009) Cholesterol in Alzheimer's disease: unresolved questions. Curr Alzheimer Res 6, 15-29.
-
(2009)
Curr Alzheimer Res
, vol.6
, pp. 15-29
-
-
Stefani, M.1
Liguri, G.2
-
70
-
-
34547118151
-
Formation of amyloids by Aβ-(1-42) on NGF-differentiated PC12 cells: roles of gangliosides and cholesterol
-
Wakabayashi M & Matsuzaki K (2007) Formation of amyloids by Aβ-(1-42) on NGF-differentiated PC12 cells: roles of gangliosides and cholesterol. J Mol Biol 371, 924-933.
-
(2007)
J Mol Biol
, vol.371
, pp. 924-933
-
-
Wakabayashi, M.1
Matsuzaki, K.2
-
71
-
-
69249209894
-
Ganglioside-induced amyloid formation by human islet amyloid polypeptide in lipid rafts
-
Wakabayashi M & Matsuzaki K (2009) Ganglioside-induced amyloid formation by human islet amyloid polypeptide in lipid rafts. FEBS Lett 583, 2854-2858.
-
(2009)
FEBS Lett
, vol.583
, pp. 2854-2858
-
-
Wakabayashi, M.1
Matsuzaki, K.2
-
72
-
-
50949111281
-
Seladin-1/dhcr24 protects neuroblastoma cells against Aβ toxicity by increasing membrane cholesterol content
-
Cecchi C, Rosati F, Pensalfini A, Formigli L, Nosi D, Liguri G, Dichiara F, Morello M, Danza G, Pieraccini G et al. (2008) Seladin-1/dhcr24 protects neuroblastoma cells against Aβ toxicity by increasing membrane cholesterol content. J Cell Mol Med 12, 1990-2002.
-
(2008)
J Cell Mol Med
, vol.12
, pp. 1990-2002
-
-
Cecchi, C.1
Rosati, F.2
Pensalfini, A.3
Formigli, L.4
Nosi, D.5
Liguri, G.6
Dichiara, F.7
Morello, M.8
Danza, G.9
Pieraccini, G.10
-
73
-
-
14844321855
-
Cholesterol homeostasis failure as a unifying cause of synaptic degeneration
-
Koudinov AL & Koudinova NV (2005) Cholesterol homeostasis failure as a unifying cause of synaptic degeneration. J Neurol Sci 229-230, 233-240.
-
(2005)
J Neurol Sci
, pp. 233-240
-
-
Koudinov, A.L.1
Koudinova, N.V.2
-
74
-
-
43149118349
-
Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane
-
Engel MF, Khemtémourian L, Kleijer CC, Meeldijk HJ, Jacobs J, Verkeij AI, De Kruijff B, Killan JA & Höppener JK (2008) Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane. Proc Natl Acad Sci USA 105, 6033-6038.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 6033-6038
-
-
Engel, M.F.1
Khemtémourian, L.2
Kleijer, C.C.3
Meeldijk, H.J.4
Jacobs, J.5
Verkeij, A.I.6
De Kruijff, B.7
Killan, J.A.8
Höppener, J.K.9
-
75
-
-
71749089460
-
Fibril fragmentation enhances amyloid cytotoxicity
-
Xue W-F, Hellewell AL, Gosal WS, Homans SW, Hewitt EW & Radford SE (2009) Fibril fragmentation enhances amyloid cytotoxicity. J Biol Chem 284, 34272-34282.
-
(2009)
J Biol Chem
, vol.284
, pp. 34272-34282
-
-
Xue, W.1
Hellewell, A.L.2
Gosal, W.S.3
Homans, S.W.4
Hewitt, E.W.5
Radford, S.E.6
-
76
-
-
38049056730
-
Lipids revert inert Abeta amyloid fibrils to neurotoxic protofibrils that affect learning in mice
-
Martins IC, Kuperstein I, Wilkinson H, Maes E, Vambrabant M, Jonckheere W, Van Gelder P, Hartmann D, D'Hooge R, De Strooper B et al. (2008) Lipids revert inert Abeta amyloid fibrils to neurotoxic protofibrils that affect learning in mice. EMBO J 27, 224-233.
-
(2008)
EMBO J
, vol.27
, pp. 224-233
-
-
Martins, I.C.1
Kuperstein, I.2
Wilkinson, H.3
Maes, E.4
Vambrabant, M.5
Jonckheere, W.6
Van Gelder, P.7
Hartmann, D.8
D'Hooge, R.9
De Strooper, B.10
-
77
-
-
0028914019
-
Interaction of the anthracycline 4'-iodo-4'-deoxydoxorubicin with amyloid fibrils: inhibition of amyloidogenesis
-
Merlini G, Ascari E, Amboldi N, Bellotti V, Arbustini E, Perfetti V, Ferrari M, Zorzoli I, Marinone MG, Garini P et al. (1995) Interaction of the anthracycline 4'-iodo-4'-deoxydoxorubicin with amyloid fibrils: inhibition of amyloidogenesis. Proc Natl Acad Sci USA 92, 2959-2963.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 2959-2963
-
-
Merlini, G.1
Ascari, E.2
Amboldi, N.3
Bellotti, V.4
Arbustini, E.5
Perfetti, V.6
Ferrari, M.7
Zorzoli, I.8
Marinone, M.G.9
Garini, P.10
-
78
-
-
33644919388
-
Doxycycline disrupts transthyretin amyloid: evidence from studies in a FAP transgenic mice model
-
Cardoso I & Saraiva MJ (2006) Doxycycline disrupts transthyretin amyloid: evidence from studies in a FAP transgenic mice model. FASEB J 20, 234-239.
-
(2006)
FASEB J
, vol.20
, pp. 234-239
-
-
Cardoso, I.1
Saraiva, M.J.2
-
79
-
-
23144459082
-
Molecular recycling within amyloid fibrils
-
Carulla N, Caddy GL, Hall DR, Zurdo J, Gairi M, Feliz M, Giralt E, Robinson CV & Dobson CM (2005) Molecular recycling within amyloid fibrils. Nature 436, 554-558.
-
(2005)
Nature
, vol.436
, pp. 554-558
-
-
Carulla, N.1
Caddy, G.L.2
Hall, D.R.3
Zurdo, J.4
Gairi, M.5
Feliz, M.6
Giralt, E.7
Robinson, C.V.8
Dobson, C.M.9
-
80
-
-
70349973683
-
Biochemical and immunohistochemical analysis of an Alzheimer's disease mouse model reveals the presence of multiple cerebral Aβ assembly forms throughout life
-
Shankar GM, Leissring MA, Adame A, Sun X, Spooner E, Masliah E, Selkoe DJ, Lemere CA & Walsh DM (2009) Biochemical and immunohistochemical analysis of an Alzheimer's disease mouse model reveals the presence of multiple cerebral Aβ assembly forms throughout life. Neurobiol Dis 36, 293-302.
-
(2009)
Neurobiol Dis
, vol.36
, pp. 293-302
-
-
Shankar, G.M.1
Leissring, M.A.2
Adame, A.3
Sun, X.4
Spooner, E.5
Masliah, E.6
Selkoe, D.J.7
Lemere, C.A.8
Walsh, D.M.9
-
81
-
-
33750480868
-
Characterization of the nanoscale properties of individual amyloid fibrils
-
Smith JF, Knowles TPJ, Dobson CM, MacPhee CE & Welland ME (2006) Characterization of the nanoscale properties of individual amyloid fibrils. Proc Natl Acad Sci USA 103, 15806-15811.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 15806-15811
-
-
Smith, J.F.1
Knowles, T.P.J.2
Dobson, C.M.3
MacPhee, C.E.4
Welland, M.E.5
-
82
-
-
59649110455
-
Abeta(1-40) fibril polymorphism implies diverse interaction patterns in amyloid fibrils
-
Meinhardt J, Sachse C, Hortschansky P, Grigorieff N & Fandrich M (2009) Abeta(1-40) fibril polymorphism implies diverse interaction patterns in amyloid fibrils. J Mol Biol 386, 869-877.
-
(2009)
J Mol Biol
, vol.386
, pp. 869-877
-
-
Meinhardt, J.1
Sachse, C.2
Hortschansky, P.3
Grigorieff, N.4
Fandrich, M.5
-
83
-
-
27644528932
-
A single disulfide bond differentiates aggregation pathways of β2-microglobulin
-
Chen Y & Kokholyan N (2005) A single disulfide bond differentiates aggregation pathways of β2-microglobulin. J Mol Biol 354, 473-482.
-
(2005)
J Mol Biol
, vol.354
, pp. 473-482
-
-
Chen, Y.1
Kokholyan, N.2
-
84
-
-
60349121505
-
Identification of physiological and toxic conformations in Aβ42 aggregates
-
Masuda Y, Uemura S, Ohashi R, Nakanishi A, Takegoshi K, Shimizu T, Shirasawa T & Irie K (2009) Identification of physiological and toxic conformations in Aβ42 aggregates. Chembiochem 10, 287-295.
-
(2009)
Chembiochem
, vol.10
, pp. 287-295
-
-
Masuda, Y.1
Uemura, S.2
Ohashi, R.3
Nakanishi, A.4
Takegoshi, K.5
Shimizu, T.6
Shirasawa, T.7
Irie, K.8
-
85
-
-
33947719234
-
Role of aggregation conditions in the structure, stability, and toxicity of intermediates in the Aβ fibril formation pathway
-
Lee S, Fernandez EJ & Good TA (2007) Role of aggregation conditions in the structure, stability, and toxicity of intermediates in the Aβ fibril formation pathway. Protein Sci 16, 723-732.
-
(2007)
Protein Sci
, vol.16
, pp. 723-732
-
-
Lee, S.1
Fernandez, E.J.2
Good, T.A.3
-
86
-
-
0032548943
-
Structural transitions associated with the interaction of Alzheimer's β-amyloid peptides with gangliosides
-
Mclaurin J, Franklin T, Fraser PE & Chakrabarty A (1997) Structural transitions associated with the interaction of Alzheimer's β-amyloid peptides with gangliosides. J Biol Chem 273, 4506-4515.
-
(1997)
J Biol Chem
, vol.273
, pp. 4506-4515
-
-
Mclaurin, J.1
Franklin, T.2
Fraser, P.E.3
Chakrabarty, A.4
-
87
-
-
67649856863
-
Distinct conformations of invitro and invivo amyloids of huntingtin-exon1 show different cytotoxicity
-
Nekooki-Machida Y, Kurosawa M, Nukina N, Ito K, Oda T & Tanaka M (2009) Distinct conformations of invitro and invivo amyloids of huntingtin-exon1 show different cytotoxicity. Proc Natl Acad Sci USA 106, 9679-9684.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 9679-9684
-
-
Nekooki-Machida, Y.1
Kurosawa, M.2
Nukina, N.3
Ito, K.4
Oda, T.5
Tanaka, M.6
-
88
-
-
15844403848
-
Annular α-synuclein oligomers are potentially toxic agents in α-synucleinopathy
-
Pountney DL, Voelcker NH & Gai WP (2005) Annular α-synuclein oligomers are potentially toxic agents in α-synucleinopathy. Neurotox Res 7, 59-67.
-
(2005)
Neurotox Res
, vol.7
, pp. 59-67
-
-
Pountney, D.L.1
Voelcker, N.H.2
Gai, W.P.3
-
89
-
-
24344467958
-
Insights into the molecular basis of the differing susceptibility of varying cell types to the toxicity of amyloid aggregates
-
Cecchi C, Baglioni S, Fiorillo C, Pensalfini A, Liguri G, Nosi D, Rigacci S, Bucciantini M & Stefani M (2005) Insights into the molecular basis of the differing susceptibility of varying cell types to the toxicity of amyloid aggregates. J Cell Sci 118, 3459-3470.
-
(2005)
J Cell Sci
, vol.118
, pp. 3459-3470
-
-
Cecchi, C.1
Baglioni, S.2
Fiorillo, C.3
Pensalfini, A.4
Liguri, G.5
Nosi, D.6
Rigacci, S.7
Bucciantini, M.8
Stefani, M.9
-
90
-
-
33750581641
-
Selective vulnerability of different types of commissural neurons for amyloid beta-protein-induced neurodegeneration in APP23 mice correlates with dendritic tree morphology
-
Capetillo-Zarate E, Staufenbiel M, Abramowski D, Haass C, Escher A, Stadelmann C, Yamaguchi H, Wiestler OD & Thal DR (2006) Selective vulnerability of different types of commissural neurons for amyloid beta-protein-induced neurodegeneration in APP23 mice correlates with dendritic tree morphology. Brain 129, 2992-3005.
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(2006)
Brain
, vol.129
, pp. 2992-3005
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Capetillo-Zarate, E.1
Staufenbiel, M.2
Abramowski, D.3
Haass, C.4
Escher, A.5
Stadelmann, C.6
Yamaguchi, H.7
Wiestler, O.D.8
Thal, D.R.9
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