Stereoselective interactions of peptide inhibitors with the β-amyloid peptide

Journal of Biological Chemistry

Volumn 278, Issue 37, 2003, Pages 34874-34881

  Chalifour, Robert J ^b   McLaughlin, Richard W ^b   Lavoie, Louis ^b   Morissette, Céline ^b   Tremblay, Nadine ^b   Boulé, Marie ^b   Sarazin, Philippe ^b   Stéa, Dino ^b   Lacombe, Diane ^b   Tremblay, Patrick ^b   Gervais, Francine ^a  

^a Neurochem Inc   (Canada)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ELECTRON MICROSCOPY; PROTEINS; STEREOCHEMISTRY;

ENANTIOMERIC PROTEINS;

BIOCHEMISTRY;

AMINO ACID; AMYLOID BETA PROTEIN; DEXTRO AMINO ACID; LYSYLISOLEUCYLVALYLPHENYLALANYLPHENYLALANYLALANINE; LYSYLLEUCYLVALYLPHENYLALANYLPHENYLALANYLALANINE; LYSYLLYSYLLEUCYLVALYLPHENYLALANYLPHENYLALANYLALANINE; LYSYLPHENYLALANYLVALYLPHENYLALANYLPHENYLALANYLALANINE; LYSYLVALYLVALYLPHENYLALANYLPHENYLALANYLALANINE; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BETA SHEET; CHIRALITY; CIRCULAR DICHROISM; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG DESIGN; DRUG MECHANISM; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTRON MICROSCOPY; ENANTIOMER; FETUS; IN VITRO STUDY; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN MOTIF; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; RAT; STEREOCHEMISTRY;

AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN; CIRCULAR DICHROISM; KINETICS; NEUROTOXINS; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; SPECTROPHOTOMETRY, ULTRAVIOLET; STEREOISOMERISM;

ANIMALIA;

EID: 0042818327     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M212694200     Document Type: Article

References (38)

1. Glenner, G. G., and Wong, C. W. (1984) Biochem. Biophys. Res. Commun. 120, 885-890
2. Selkoe, D. J. (2001) Physiol. Rev. 81, 741-766
3. Pike, C. J., Burdick, D., Walencewicz, A. J., Glabe, C. G., and Cotman, C. W. (1993) J. Neurosci. 13, 1676-1687
4. Lorenzo, A., and Yankner, B. A. (1994) Proc. Natl. Acad, Sci. U. S. A. 91, 12243-12247
5. Schenk, D., Barbour, R., Dunn, W., Gordon, G., Grajeda, H., Guido, T., Hu, K., Huang, J., Johnson-Wood, K., Khan, K., Kholodenko, D., Lee, M., Liao, Z., Lieberburg, I., Motter, R., Mutter, L., Soriano, F., Shopp, G., Vasquez, N., Vandevert, C., Walker, S., Wogulis, M., Yednock, T., Games, D., and Seubert, P. (1999) Nature 400, 173-177
6. Janus, C., Pearson, J., McLaurin, J., Mathews, P. M., Jiang, Y., Schmidt, S. D., Chishti, M. A., Horne, P., Heslin, D., French, J., Mount, H. T., Nixon, R. A., Mercken, M., Bergeron, C., Fraser, P. E., St George-Hyslop, P., and Westaway, D. (2000) Nature 408, 979-982
7. Morgan, D., Diamond, D. M., Gottschall, P. E., Ugen, K. E., Dickey, C., Hardy, J., Duff, K., Jantzen, P., DiCarlo, G., Wilcock, D., Connor, K., Hatcher, J., Hope, C., Gordon, M., and Arendash, G. W. (2000) Nature 408, 982-985
8. Roher, A. E., Chaney, M. O., Kuo, Y. M., Webster, S. D., Stine, W. B., Haverkamp, L. J., Wood, A. S., Cotter, R. J., Tuohy, J. M., Krafft, G. A., Bonnell, B. S., and Emmerling, M. R. (1996) J. Biol. Chem. 271, 20631-20635
9. Walsh, D. M., Klyubin, I., Fadeeva, J. V., Cullen, W. K., Anwyl, R., Wolfe, M. S., Rowan, M. J., and Selkoe, D. J. (2002) Nature 416, 535-539
10. Lambert, M. P., Barlow, A. K., Chromy, B. A., Edwards, C., Freed, R., Liosatos, M., Morgan, T. E., Rozovsky, I., Trommer, B., Viola, K. L., Wals, P., Zhang, C., Finch, C. E., Krafft, G. A., and Klein, W. L. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 6448-6453
11. Kuner, P., Bohrmann, B., Tjernberg, L. O., Naslund, J., Huber, G., Celenk, S., Gruninger-Leitch, F., Richards, J. G., Jakob-Roetne, R., Kemp, J. A., and Nordstedt, C. (2000) J. Biol. Chem. 275, 1673-1678
12. McLaurin, J., Golomb, R., Jurewicz, A., Antel, J. P., and Fraser, P. E. (2000) J. Biol. Chem. 275, 18495-18502
13. Yang, D. S., Serpell, L. C., Yip, C. M., McLaurin, J., Chrishti, M. A., Horne, P., Boudreau, L., Kisilevsky, R., Westaway, D., and Fraser, P. E. (2001) Amyloid 8, Suppl. 1, 10-19
14. Hilbich, C., Kisters-Woike, B., Reed, J., Masters, C. L., and Beyreuther, K. (1992) J. Mol. Biol. 228, 460-473
15. Esler, W. P., Stimson, E. R., Ghilardi, J. R., Lu, Y. A., Felix, A. M., Vinters, H. V., Mantyh, P. W., Lee, J. P., and Maggio, J. E. (1996) Biochemistry 35, 13914-13921
16. Tjernberg, L. O., Naslund, J., Lindqvist, F., Johansson, J., Karlstrom, A. R., Thyberg, J., Terenius, L., and Nordstedt, C. (1996) J. Biol. Chem. 271, 8545-8548
17. Tjernberg, L. O., Lilliehook, C., Callaway, D. J., Naslund, J., Hahne, S., Thyberg, J., Terenius, L., and Nordstedt, C. (1997) J. Biol. Chem. 272, 12601-12605
18. Soto, C., Kindy, M. S., Baumann, M., and Frangione, B. (1996) Biochem. Biophys. Res. Commun. 226, 672-680
19. Ghanta, J., Shen, C. L., Kiessling, L. L., and Murphy, R. M. (1996) J. Biol. Chem. 271, 29525-29528
20. Findeis, M. A., Musso, G. M., Arico-Muendel, C. C., Benjamin, H. W., Hundal, A. M., Lee, J. J., Chin, J., Kelley, M., Wakefield, J., Hayward, N. J., and Molineaux, S. M. (1999) Biochemistry 38, 6791-6800
21. Gordon, D. J., Sciarretta, K. L., and Meredith, S. C. (2001) Biochemistry 40, 8237-8245
22. Esler, W. P., Stimson, E. R., Fishman, J. B., Ghilardi, J. R., Vinters, H. V., Mantyh, P. W., and Maggio, J. E. (1999) Biopolymers 49, 505-514
23. Milton, R. C., Milton, S. C., and Kent, S. B. (1992) Science 256, 1445-1448
24. Walsh, D. M., Lomakin, A., Benedek, G. B., Condron, M. M., and Teplow, D. B. (1997) J. Biol. Chem. 272, 22364-22372
25. Wall, J., Schell, M., Murphy, C., Hrncic, R., Stevens, F. J., and Solomon, A. (1999) Biochemistry 38, 14101-14108
26. LeVine, H., III. (1993) Protein Sci. 2, 404-410
27. Reed, J., and Reed, T. A. (1997) Anal. Biochem. 254, 36-40
28. Colon, W. (1999) Methods Enzymol. 309, 605-632
29. Hasegawa, K., Yamaguchi, I., Omata, S., Gejyo, F., and Naiki, H. (1999) Biochemistry 38, 15514-15521
30. McLaurin, J., Franklin, T., Zhang, X., Deng, J., and Fraser, P. E. (1999) Eur. J. Biochem. 266, 1101-1110
31. Corigliano-Murphy, M. A., Xun, L. A., Ponnamperuma, C., Dalzoppo, D., Fontana, A., Kanmera, T., and Chaiken, I. M. (1985) Int. J. Pept. Protein Res. 25, 225-231
32. Pritsker, M., Jones, P., Blumenthal, R., and Shai, Y. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 7287-7292
33. Feifel, B., Schonfeld, H. J., and Christen, P. (1998) J. Biol. Chem. 273, 11999-12002
34. Atwood, C. S., Scarpa, R. C., Huang, X., Moir, R. D., Jones, W. D., Fairlie, D. P., Tanzi, R. E., and Bush, A. I. (2000) J. Neurochem. 75, 1219-1233
35. Janek, K., Rothemund, S., Gast, K., Beyermann, M., Zipper, J., Fabian, H., Bienert, M., and Krause, E. (2001) Biochemistry 40, 5457-5463
36. Wisniewski, T., and Frangione, B. (1992) Neurosci. Lett. 135, 235-238
37. Ma, J., Yee, A., Brewer, H. B., Jr., Das, S., and Potter, H. (1994) Nature 372, 92-94
38. Lowe, T. L., Strzelec, A., Kiessling, L. L., and Murphy, R. M. (2001) Biochemistry 40, 7882-7889