Binding of nonsteroidal anti-inflammatory drugs to Aβ fibril

Proteins: Structure, Function and Bioinformatics

Volumn 78, Issue 13, 2010, Pages 2849-2860

  Takeda, Takako ^a   Chang, Wenling E ^a,b   Raman, E Prabhu ^c   Klimov, Dmitri K ^a  

^a GEORGE MASON UNIVERSITY   (United States)

^b MITRE CORPORATION   (United States)

^c UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

Author keywords

A peptides; Amyloid fibril; Ibuprofen; Ligand binding; Naproxen; Replica exchange molecular dynamics

Indexed keywords

AMYLOID BETA PROTEIN; IBUPROFEN; NAPHTHALENE; NAPROXEN;

ARTICLE; BINDING AFFINITY; BINDING SITE; DRUG PROTEIN BINDING; PRIORITY JOURNAL; PROTEIN STRUCTURE; SIMULATION; THERMODYNAMICS;

AMINO ACID SEQUENCE; AMYLOID BETA-PEPTIDES; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BINDING SITES; BINDING, COMPETITIVE; COMPUTER SIMULATION; HUMANS; IBUPROFEN; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; NAPROXEN; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; TEMPERATURE;

EID: 77957959117     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.22804     Document Type: Article

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