Combination of kinetically selected inhibitors in trans leads to highly effective inhibition of amyloid formation

Journal of the American Chemical Society

Volumn 132, Issue 41, 2010, Pages 14340-14342

  Meng, Fanling ^a   Raleigh, Daniel P ^a   Abedini, Andisheh ^b  

^a STONY BROOK UNIVERSITY   (United States)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER'S DISEASE; AMYLOID FIBRIL; AMYLOID FORMATION; CAUSATIVE AGENTS; HUMAN DISORDERS; KEY FEATURE; KINETIC ASSAY; LAG-TIME; MOLAR EXCESS; TIME COURSE; TYPE-2 DIABETES;

FEATURE EXTRACTION;

GLYCOPROTEINS;

AMYLIN; AMYLOID; AMYLOID BETA PROTEIN[1-40]; PROTEIN INHIBITOR; THIOFLAVINE;

AMINO ACID SEQUENCE; ARTICLE; DRUG INHIBITION; KINETICS; POINT MUTATION; PROTEIN AGGREGATION; TRANSMISSION ELECTRON MICROSCOPY;

AMINO ACID SEQUENCE; AMYLOID; CIRCULAR DICHROISM; ISLET AMYLOID POLYPEPTIDE; KINETICS; MICROSCOPY, ELECTRON, TRANSMISSION; MOLECULAR SEQUENCE DATA;

EID: 77958065164     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja1046186     Document Type: Article

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