Candidate anti-Aβ fluorene compounds selected from analogs of amyloid imaging agents

Neurobiology of Aging

Volumn 31, Issue 10, 2010, Pages 1690-1699

  Hong, Hyun Seok ^a   Maezawa, Izumi ^a   Budamagunta, Madhu ^b   Rana, Sandeep ^c   Shi, Aibin ^c   Vassar, Robert ^d   Liu, Ruiwu ^e   Lam, Kit S ^e   Cheng, R Holland ^f   Hua, Duy H ^c   Voss, John C ^b   Jin, Lee Way ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c KANSAS STATE UNIVERSITY   (United States)

^d NORTHWESTERN UNIVERSITY   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Alzheimer's disease; Amyloid ligand; Amyloid ; Electron paramagnetic resonance spectroscopy; Oligomer; Small molecules; Spin label; Synapse

Indexed keywords

AMYLOID BETA PROTEIN; FLUORENE DERIVATIVE; K 01 162; K 01 186; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; DRUG POTENCY; DRUG PROTEIN BINDING; IC 50; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NERVE CELL CULTURE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; SYNAPSE;

ALZHEIMER DISEASE; AMYLOID; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BRAIN; CELLS, CULTURED; DIMETHYLAMINES; FLUORENES; HUMANS; MICE; MICE, TRANSGENIC; PROTEIN CONFORMATION;

EID: 77955841406     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2008.09.019     Document Type: Article

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