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Volumn 45, Issue 13, 2008, Pages 3649-3660

C4b-binding protein in Alzheimer's disease: Binding to Aβ1-42 and to dead cells

Author keywords

Apoptosis; C4BP; Complement; Dementia

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; COMPLEMENT COMPONENT C4B BINDING PROTEIN;

EID: 46749123000     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2008.04.025     Document Type: Article
Times cited : (48)

References (55)
  • 3
    • 0034351825 scopus 로고    scopus 로고
    • A cluster of positively charged amino acids in the alpha-chain of C4b-binding-protein (C4BP) is pivotal for the regulation of the complement system and the interaction with bacteria
    • Blom A.M. A cluster of positively charged amino acids in the alpha-chain of C4b-binding-protein (C4BP) is pivotal for the regulation of the complement system and the interaction with bacteria. Scand. J. Clin. Lab. Invest. (Suppl.) 233 (2000) 37-49
    • (2000) Scand. J. Clin. Lab. Invest. (Suppl.) , vol.233 , pp. 37-49
    • Blom, A.M.1
  • 4
    • 0035920160 scopus 로고    scopus 로고
    • Structural requirements for the complement regulatory activities of C4BP
    • Blom A.M., Kask L., and Dahlbäck B. Structural requirements for the complement regulatory activities of C4BP. J. Biol. Chem. 276 (2001) 27136-27144
    • (2001) J. Biol. Chem. , vol.276 , pp. 27136-27144
    • Blom, A.M.1    Kask, L.2    Dahlbäck, B.3
  • 5
    • 1842557722 scopus 로고    scopus 로고
    • Complement inhibitor C4b-binding protein-friend or foe in the innate immune system?
    • Blom A.M., Villoutreix B.O., and Dahlbäck B. Complement inhibitor C4b-binding protein-friend or foe in the innate immune system?. Mol. Immunol. 40 (2004) 1333-1346
    • (2004) Mol. Immunol. , vol.40 , pp. 1333-1346
    • Blom, A.M.1    Villoutreix, B.O.2    Dahlbäck, B.3
  • 6
    • 0029013727 scopus 로고
    • Staging of Alzheimer's disease-related neurofibrillary changes
    • (discussion 271-84)
    • Braak H., and Braak E. Staging of Alzheimer's disease-related neurofibrillary changes. Neurobiol. Aging 16 (1995) 271-278 (discussion 271-84)
    • (1995) Neurobiol. Aging , vol.16 , pp. 271-278
    • Braak, H.1    Braak, E.2
  • 8
    • 33645079378 scopus 로고    scopus 로고
    • Complement regulator loss on apoptotic neuronal cells causes increased complement activation and promotes both phagocytosis and cell lysis
    • Cole D.S., Hughes T.R., Gasque P., and Morgan B.P. Complement regulator loss on apoptotic neuronal cells causes increased complement activation and promotes both phagocytosis and cell lysis. Mol. Immunol. 43 12 (2006) 1953-1964
    • (2006) Mol. Immunol. , vol.43 , Issue.12 , pp. 1953-1964
    • Cole, D.S.1    Hughes, T.R.2    Gasque, P.3    Morgan, B.P.4
  • 9
    • 0020530378 scopus 로고
    • Purification of human C4b-binding protein and formation of its complex with vitamin K-dependent protein S
    • Dahlbäck B. Purification of human C4b-binding protein and formation of its complex with vitamin K-dependent protein S. Biochem. J. 209 (1983) 847-856
    • (1983) Biochem. J. , vol.209 , pp. 847-856
    • Dahlbäck, B.1
  • 11
    • 0035209395 scopus 로고    scopus 로고
    • The phagocytosis of apoptotic cells
    • Fadok V.A., and Chimini G. The phagocytosis of apoptotic cells. Semin. Immunol. 13 (2001) 365-372
    • (2001) Semin. Immunol. , vol.13 , pp. 365-372
    • Fadok, V.A.1    Chimini, G.2
  • 13
    • 0041563779 scopus 로고    scopus 로고
    • Obstacles to cancer immunotherapy: expression of membrane complement regulatory proteins (mCRPs) in tumors
    • Fishelson Z., Donin N., Zell S., Schultz S., and Kirschfink M. Obstacles to cancer immunotherapy: expression of membrane complement regulatory proteins (mCRPs) in tumors. Mol. Immunol. 40 (2003) 109-123
    • (2003) Mol. Immunol. , vol.40 , pp. 109-123
    • Fishelson, Z.1    Donin, N.2    Zell, S.3    Schultz, S.4    Kirschfink, M.5
  • 14
    • 0016823810 scopus 로고
    • "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician
    • Folstein M.F., Folstein S.E., and McHugh P.R. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J. Psychiatr. Res. 12 (1975) 189-198
    • (1975) J. Psychiatr. Res. , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 15
    • 0028103281 scopus 로고
    • Differential regulation of alpha and beta chains of C4b-binding protein during acute-phase response resulting in stable plasma levels of free anticoagulant protein S
    • Garcia de Frutos P., Alim R.I., Härdig Y., Zoller B., and Dahlbäck B. Differential regulation of alpha and beta chains of C4b-binding protein during acute-phase response resulting in stable plasma levels of free anticoagulant protein S. Blood 84 (1994) 815-822
    • (1994) Blood , vol.84 , pp. 815-822
    • Garcia de Frutos, P.1    Alim, R.I.2    Härdig, Y.3    Zoller, B.4    Dahlbäck, B.5
  • 16
    • 0028787494 scopus 로고
    • Serum amyloid P component binding to C4b-binding protein
    • Garcia de Frutos P., Härdig Y., and Dahlbäck B. Serum amyloid P component binding to C4b-binding protein. J. Biol. Chem. 270 (1995) 26950-26955
    • (1995) J. Biol. Chem. , vol.270 , pp. 26950-26955
    • Garcia de Frutos, P.1    Härdig, Y.2    Dahlbäck, B.3
  • 18
    • 0033921540 scopus 로고    scopus 로고
    • Complement components of the innate immune system in health and disease in the CNS
    • Gasque P., Dean Y.D., McGreal E.P., VanBeek J., and Morgan B.P. Complement components of the innate immune system in health and disease in the CNS. Immunopharmacology 49 (2000) 171-186
    • (2000) Immunopharmacology , vol.49 , pp. 171-186
    • Gasque, P.1    Dean, Y.D.2    McGreal, E.P.3    VanBeek, J.4    Morgan, B.P.5
  • 19
    • 0027363674 scopus 로고
    • Expression of the complement classical pathway by human glioma in culture. A model for complement expression by nerve cells
    • Gasque P., Ischenko A., Legoedec J., Mauger C., Schouft M.T., and Fontaine M. Expression of the complement classical pathway by human glioma in culture. A model for complement expression by nerve cells. J. Biol. Chem. 268 (1993) 25068-25074
    • (1993) J. Biol. Chem. , vol.268 , pp. 25068-25074
    • Gasque, P.1    Ischenko, A.2    Legoedec, J.3    Mauger, C.4    Schouft, M.T.5    Fontaine, M.6
  • 20
    • 0028178458 scopus 로고
    • Beta-Amyloid activates complement by binding to a specific region of the collagen-like domain of the Clq A chain
    • Jiang H., Burdick D., Glabe C.G., Cotman C.W., and Tenner A.J. Beta-Amyloid activates complement by binding to a specific region of the collagen-like domain of the Clq A chain. J. Immunol. 152 (1994) 5050-5059
    • (1994) J. Immunol. , vol.152 , pp. 5050-5059
    • Jiang, H.1    Burdick, D.2    Glabe, C.G.3    Cotman, C.W.4    Tenner, A.J.5
  • 21
    • 0029586946 scopus 로고
    • Apoptosis is associated with reduced expression of complement regulatory molecules, adhesion molecules and other receptors on polymorphonuclear leucocytes: functional relevance and role in inflammation
    • Jones J., and Morgan B.P. Apoptosis is associated with reduced expression of complement regulatory molecules, adhesion molecules and other receptors on polymorphonuclear leucocytes: functional relevance and role in inflammation. Immunology 86 (1995) 651-660
    • (1995) Immunology , vol.86 , pp. 651-660
    • Jones, J.1    Morgan, B.P.2
  • 22
    • 0026775412 scopus 로고
    • Complement inhibitor C4-binding protein in amyloid deposits containing serum amyloid P in Alzheimer's disease
    • Kalaria R.N., and Kroon S.N. Complement inhibitor C4-binding protein in amyloid deposits containing serum amyloid P in Alzheimer's disease. Biochem. Biophys. Res. Commun. 186 (1992) 461-466
    • (1992) Biochem. Biophys. Res. Commun. , vol.186 , pp. 461-466
    • Kalaria, R.N.1    Kroon, S.N.2
  • 23
    • 0027493189 scopus 로고
    • Amyloid P component and other acute-phase proteins associated with cerebellar A beta-deposits in Alzheimer's disease
    • Kalaria R.N., and Perry G. Amyloid P component and other acute-phase proteins associated with cerebellar A beta-deposits in Alzheimer's disease. Brain. Res. 631 (1993) 151-155
    • (1993) Brain. Res. , vol.631 , pp. 151-155
    • Kalaria, R.N.1    Perry, G.2
  • 24
    • 0037199490 scopus 로고    scopus 로고
    • Structural requirements for the intra-cellular subunit polymerization of the complement inhibitor C4b-binding protein
    • Kask L., Hillarp A., Ramesh B., Dahlbäck B., and Blom A.M. Structural requirements for the intra-cellular subunit polymerization of the complement inhibitor C4b-binding protein. Biochemistry 41 (2002) 9349-9357
    • (2002) Biochemistry , vol.41 , pp. 9349-9357
    • Kask, L.1    Hillarp, A.2    Ramesh, B.3    Dahlbäck, B.4    Blom, A.M.5
  • 25
    • 2642533647 scopus 로고    scopus 로고
    • The C4b-binding protein-protein S complex inhibits the phagocytosis of apoptotic cells
    • Kask L., Trouw L.A., Dahlbäck B., and Blom A.M. The C4b-binding protein-protein S complex inhibits the phagocytosis of apoptotic cells. J. Biol. Chem. 279 (2004) 23869-23873
    • (2004) J. Biol. Chem. , vol.279 , pp. 23869-23873
    • Kask, L.1    Trouw, L.A.2    Dahlbäck, B.3    Blom, A.M.4
  • 26
    • 0013895324 scopus 로고
    • Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodies
    • Laurell C.B. Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodies. Anal. Biochem. 15 (1966) 45-52
    • (1966) Anal. Biochem. , vol.15 , pp. 45-52
    • Laurell, C.B.1
  • 27
    • 28444435458 scopus 로고    scopus 로고
    • Inflammation, the complement system and the diseases of aging
    • McGeer E.G., Klegeris A., and McGeer P.L. Inflammation, the complement system and the diseases of aging. Neurobiol. Aging 26 Suppl. 1 (2005) 94-97
    • (2005) Neurobiol. Aging , vol.26 SUPPL. 1 , pp. 94-97
    • McGeer, E.G.1    Klegeris, A.2    McGeer, P.L.3
  • 28
    • 0035693924 scopus 로고    scopus 로고
    • Inflammation, autotoxicity and Alzheimer disease
    • McGeer P.L., and McGeer E.G. Inflammation, autotoxicity and Alzheimer disease. Neurobiol. Aging 22 (2001) 799-809
    • (2001) Neurobiol. Aging , vol.22 , pp. 799-809
    • McGeer, P.L.1    McGeer, E.G.2
  • 31
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
    • McKhann G., Drachman D., Folstein M., Katzman R., Price D., and Stadlan E.M. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34 (1984) 939-944
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3    Katzman, R.4    Price, D.5    Stadlan, E.M.6
  • 33
    • 33947205974 scopus 로고    scopus 로고
    • Soluble adhesion molecules and angiotensin-converting enzyme in dementia
    • Nielsen H.M., Londos E., Minthon L., and Janciauskiene S.M. Soluble adhesion molecules and angiotensin-converting enzyme in dementia. Neurobiol. Dis. 26 (2007) 27-35
    • (2007) Neurobiol. Dis. , vol.26 , pp. 27-35
    • Nielsen, H.M.1    Londos, E.2    Minthon, L.3    Janciauskiene, S.M.4
  • 38
    • 0034641931 scopus 로고    scopus 로고
    • Corpse clearance defines the meaning of cell death
    • Savill J., and Fadok V. Corpse clearance defines the meaning of cell death. Nature 407 (2000) 784-788
    • (2000) Nature , vol.407 , pp. 784-788
    • Savill, J.1    Fadok, V.2
  • 39
    • 33744956898 scopus 로고    scopus 로고
    • Regulation of complement activation by C-reactive protein: targeting of the inhibitory activity of C4b-binding protein
    • Sjöberg A.P., Trouw L.A., McGrath F.D., Hack C.E., and Blom A.M. Regulation of complement activation by C-reactive protein: targeting of the inhibitory activity of C4b-binding protein. J. Immunol. 176 (2006) 7612-7620
    • (2006) J. Immunol. , vol.176 , pp. 7612-7620
    • Sjöberg, A.P.1    Trouw, L.A.2    McGrath, F.D.3    Hack, C.E.4    Blom, A.M.5
  • 41
    • 84934437247 scopus 로고    scopus 로고
    • The double-edged flower: roles of complement protein Clq in neurodegenerative diseases
    • Tenner A.J., and Fonseca M.I. The double-edged flower: roles of complement protein Clq in neurodegenerative diseases. Adv. Exp. Med. Biol. 586 (2006) 153-176
    • (2006) Adv. Exp. Med. Biol. , vol.586 , pp. 153-176
    • Tenner, A.J.1    Fonseca, M.I.2
  • 42
    • 0033880688 scopus 로고    scopus 로고
    • Expression of a complete and functional complement system by human neuronal cells in vitro
    • Thomas A., Gasque P., Vaudry D., Gonzalez B., and Fontaine M. Expression of a complete and functional complement system by human neuronal cells in vitro. Int. Immunol. 12 (2000) 1015-1023
    • (2000) Int. Immunol. , vol.12 , pp. 1015-1023
    • Thomas, A.1    Gasque, P.2    Vaudry, D.3    Gonzalez, B.4    Fontaine, M.5
  • 43
    • 35348980673 scopus 로고    scopus 로고
    • C4b-binding protein and factor H compensate for the loss of membrane bound complement inhibitors to protect against excessive complement attack
    • Trouw L.A., Bengtsson A.A., Gelderman K.A., Dahlbäck B., Sturfelt G., and Blom A.M. C4b-binding protein and factor H compensate for the loss of membrane bound complement inhibitors to protect against excessive complement attack. J. Biol. Chem. 282 (2007) 28540-28548
    • (2007) J. Biol. Chem. , vol.282 , pp. 28540-28548
    • Trouw, L.A.1    Bengtsson, A.A.2    Gelderman, K.A.3    Dahlbäck, B.4    Sturfelt, G.5    Blom, A.M.6
  • 44
    • 22344454254 scopus 로고    scopus 로고
    • C4b-binding protein binds to necrotic cells and DNA, limiting DNA release and inhibiting complement activation
    • Trouw L.A., Nilsson S.C., Goncalves I., Landberg G., and Blom A.M. C4b-binding protein binds to necrotic cells and DNA, limiting DNA release and inhibiting complement activation. J. Exp. Med. 201 (2005) 1937-1948
    • (2005) J. Exp. Med. , vol.201 , pp. 1937-1948
    • Trouw, L.A.1    Nilsson, S.C.2    Goncalves, I.3    Landberg, G.4    Blom, A.M.5
  • 47
    • 0032710620 scopus 로고    scopus 로고
    • Cytokines associated with amyloid plaques in Alzheimer's disease brain stimulate human glial and neuronal cell cultures to secrete early complement proteins, but not Cl-inhibitor
    • Veerhuis R., Janssen I., De Groot C.J., Van Muiswinkel F.L., Hack C.E., and Eikelenboom P. Cytokines associated with amyloid plaques in Alzheimer's disease brain stimulate human glial and neuronal cell cultures to secrete early complement proteins, but not Cl-inhibitor. Exp. Neurol. 160 (1999) 289-299
    • (1999) Exp. Neurol. , vol.160 , pp. 289-299
    • Veerhuis, R.1    Janssen, I.2    De Groot, C.J.3    Van Muiswinkel, F.L.4    Hack, C.E.5    Eikelenboom, P.6
  • 50
    • 0035810399 scopus 로고    scopus 로고
    • Complement. First of two parts
    • Walport M.J. Complement. First of two parts. N. Engl. J. Med. 344 (2001) 1058-1066
    • (2001) N. Engl. J. Med. , vol.344 , pp. 1058-1066
    • Walport, M.J.1
  • 51
    • 0035849176 scopus 로고    scopus 로고
    • Complement. Second of two parts
    • Walport M.J. Complement. Second of two parts. N. Engl. J. Med. 344 (2001) 1140-1144
    • (2001) N. Engl. J. Med. , vol.344 , pp. 1140-1144
    • Walport, M.J.1
  • 52
    • 0036721697 scopus 로고    scopus 로고
    • Vitamin K-dependent protein S localizing complement regulator C4b-binding protein to the surface of apoptotic cells
    • Webb J.H., Blom A.M., and Dahlbäck B. Vitamin K-dependent protein S localizing complement regulator C4b-binding protein to the surface of apoptotic cells. J. Immunol. 169 (2002) 2580-2586
    • (2002) J. Immunol. , vol.169 , pp. 2580-2586
    • Webb, J.H.1    Blom, A.M.2    Dahlbäck, B.3
  • 53
    • 0038509115 scopus 로고    scopus 로고
    • The binding of protein S and the protein S-C4BP complex to neutrophils is apoptosis-dependent
    • Webb J.H., Blom A.M., and Dahlbäck B. The binding of protein S and the protein S-C4BP complex to neutrophils is apoptosis-dependent. Blood Coagul. Fibrinolysis 14 (2003) 355-359
    • (2003) Blood Coagul. Fibrinolysis , vol.14 , pp. 355-359
    • Webb, J.H.1    Blom, A.M.2    Dahlbäck, B.3
  • 54
    • 0036685522 scopus 로고    scopus 로고
    • Inflammation in neurodegenerative disease-a double edged sword
    • Wyss-Coray T., and Mucke L. Inflammation in neurodegenerative disease-a double edged sword. Neuron 35 (2002) 419-432
    • (2002) Neuron , vol.35 , pp. 419-432
    • Wyss-Coray, T.1    Mucke, L.2
  • 55
    • 0028787769 scopus 로고
    • Distribution of beta amyloid associated proteins in plaques in Alzheimer's disease and in the non-demented elderly
    • Zhan S.S., Veerhuis R., Kamphorst W., and Eikelenboom P. Distribution of beta amyloid associated proteins in plaques in Alzheimer's disease and in the non-demented elderly. Neurodegeneration 4 (1995) 291-297
    • (1995) Neurodegeneration , vol.4 , pp. 291-297
    • Zhan, S.S.1    Veerhuis, R.2    Kamphorst, W.3    Eikelenboom, P.4


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