Intraneuronal Aβ, non-amyloid aggregates and neurodegeneration in a Drosophila model of Alzheimer's disease

Neuroscience

Volumn 132, Issue 1, 2005, Pages 123-135

  Crowther, D C ^a   Kinghorn, K J ^a   Miranda, E ^a   Page, R ^a   Curry, J A ^c   Duthie, F A I ^b   Gubb, D C ^b   Lomas, D A ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

Author keywords

Arctic; A peptide; Conformational; Dementia; Drug screen

Indexed keywords

CONGO RED; OLIGOMER; PEPTIDE; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN (1 42); AMYLOID BETA-PROTEIN (1-42); NEUROPROTECTIVE AGENT; PEPTIDE FRAGMENT;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CELL VACUOLE; CONTROLLED STUDY; DISEASE MODEL; DISEASE SEVERITY; DROSOPHILA MELANOGASTER; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IN VITRO STUDY; MOTOR DYSFUNCTION; MUTANT; NERVE DEGENERATION; NEUROPATHOLOGY; NONHUMAN; OLIGOMERIZATION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; WILD TYPE; ANIMAL; BRAIN; CELL INCLUSION; GENETICS; LONGEVITY; METABOLISM; NERVE CELL; NERVOUS SYSTEM; PATHOLOGY; PATHOPHYSIOLOGY; TRANSGENE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; BRAIN; CONGO RED; DISEASE MODELS, ANIMAL; DROSOPHILA MELANOGASTER; INCLUSION BODIES; LONGEVITY; MOVEMENT DISORDERS; NERVE DEGENERATION; NERVOUS SYSTEM; NEURONS; NEUROPROTECTIVE AGENTS; PEPTIDE FRAGMENTS; TRANSGENES; VACUOLES;

EID: 15044339964     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2004.12.025     Document Type: Article

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