A peptide hairpin inhibitor of amyloid β-protein oligomerization and fibrillogenesis

Biochemistry

Volumn 48, Issue 48, 2009, Pages 11329-11331

  Yamin, Ghiam ^a,b   Ruchala, Piotr ^a   Teplow, David B ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER'S DISEASE; DEFENSINS; DISULFIDE BONDS; FIBRIL FORMATION; FIBRILLOGENESIS; INHIBITORY ACTIVITY; THERAPEUTIC VALUES;

AMINO ACIDS; GLYCOPROTEINS; OLIGOMERIZATION; ORGANIC ACIDS;

PEPTIDES;

AMYLOID BETA PROTEIN; DEFENSIN; DEFENSIN DERIVATIVE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; DISULFIDE BOND; DRUG ACTIVITY; DRUG STRUCTURE; FIBROGENESIS; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN MOTIF;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOID; AMYLOID BETA-PROTEIN; BINDING SITES; DIPEPTIDES; DISULFIDES; ENDOPEPTIDASES; LEUCINE; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN BINDING;

EID: 73149091019     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi901325g     Document Type: Article

References (18)

1. Brookmeyer, R., Johnson, E., Ziegler-Graham, K., and Arrighi, H. M. (2007) Alzheimer's Dementia 3, 186-191.
2. Heron, M. P., and Smith, B. L. (2007) Natl. Vital Stat. Rep. 55, 1-92.
3. Goedert, M., and Spillantini, M. G. (2006) Science 314, 777-781.
4. Roychaudhuri, R., Yang, M., Hoshi, M. M., and Teplow, D. B. (2009) J. Biol. Chem. 284, 4749-4753.
5. Selkoe, D. J. (2008) Behav. Brain Res. 192, 106-113.
6. Yamin, G., Ono, K., Inayathullah, M., and Teplow, D. B. (2008) Curr. Pharm. Des. 14, 3231-3246.
7. Soto, C., Sigurdsson, E. M., Morelli, L., Kumar, R. A., Castaño, E. M., and Frangione, B. (1998) Nat. Med. 4, 822-826.
8. Sciarretta, K. L., Boire, A., Gordon, D. J., and Meredith, S. C. (2006) Biochemistry 45, 9485-9495.
9. Fradinger, E. A., Monien, B. H., Urbanc, B., Lomakin, A., Tan, M., Li, H., Spring, S. M., Condron, M. M., Cruz, L., Xie, C. W., Benedek, G. B., and Bitan, G. (2008) Proc. Natl. Acad. Sci. U.S.A. 105, 14175-14180.
10. Wang, W., Owen, S. M., Rudolph, D. L., Cole, A. M., Hong, T., Waring, A. J., Lal, R. B., and Lehrer, R. I. (2004) J. Immunol. 173, 515-520.
11. Robinson, J. A. (2008) Acc. Chem. Res. 41, 1278-1288.
12. Bean, J. W., Kopple, K. D., and Peishoff, C. E. (1992) J. Am. Chem. Soc. 114, 5328-5334.
13. Rosengren, K. J., McManus, A. M., and Craik, D. J. (2002) Curr. Med. Chem.: Anti-Infect. Agents 1, 319-341.
14. Ahn, J. S., Lee, J., Kim, J., and Paik, S. R. (2007) Anal. Biochem. 367, 259-265.
15. Bitan, G., Kirkitadze, M. D., Lomakin, A., Vollers, S. S., Benedek, G. B., and Teplow, D. B. (2003) Proc. Natl. Acad. Sci. U.S.A. 100, 330-335.
16. Feng, B. Y., Toyama, B. H., Wille, H., Colby, D. W., Collins, S. R., May, B. C. H., Prusiner, S. B., Weissman, J., and Shoichet, B. K. (2008) Nat. Chem. Biol. 4, 197-199.
17. Yamin, G., Munishkina, L. A., Karymov, M. A., Lyubchenko, Y. L., Uversky, V. N., and Fink, A. L. (2005) Biochemistry 44, 9096-9107.
18. Hashimoto, M., Rockenstein, E., Mante, M., Mallory, M., and Masliah, E. (2001) Neuron 32, 213-223.