Reversal of temperature-induced conformational changes in the amyloid-beta peptide, Aβ40, by the β-sheet breaker peptides 16-23 and 17-24

British Journal of Pharmacology

Volumn 158, Issue 4, 2009, Pages 1165-1172

  Hatip, Funda F Bölükbaşi ^b   Suenaga, Midori ^b   Yamada, Tatsuo ^c   Matsunaga, Yoichi ^a  

^a TOKUSHIMA BUNRI UNIVERSITY   (Japan)

^b PAMUKKALE UNIVERSITY   (Turkey)

^c FUKUOKA UNIVERSITY   (Japan)

Author keywords

sheet formation; Alzheimer's disease treatment; Amyloid 1 40; Breaker peptides; Temperature

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; EPITOPE; OCTAPEPTIDE; PROTEINASE K;

ARTICLE; BETA SHEET; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; TEMPERATURE SENSITIVITY; THERMOSTABILITY;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN; CIRCULAR DICHROISM; ENDOPEPTIDASE K; EPITOPES; HUMANS; HYDROGEN-ION CONCENTRATION; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; TEMPERATURE; TIME FACTORS;

EID: 70350131474     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2009.00384.x     Document Type: Article

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