A variety of roles for versatile zinc in metallo-β-lactamases

Metallomics

Volumn 6, Issue 7, 2014, Pages 1181-1197

  Karsisiotis, A I ^a   Damblon, C F ^b   Roberts, G C K ^c  

^a UNIVERSITY OF ESSEX   (United Kingdom)

^b UNIVERSITY OF LIÈGE   (Belgium)

^c UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYMES; IONS;

CATALYTIC MECHANISMS; CLOSE PROXIMITY; NUCLEOPHILIC ATTACK; PATHOGENIC BACTERIUM; POSITIVE COOPERATIVITY; PRODUCT COMPLEX; SUBSTRATE BINDING; TETRAHEDRAL INTERMEDIATES;

ZINC;

METALLO BETA LACTAMASE; ZINC; BETA LACTAM; BETA LACTAMASE;

AMINO ACID SEQUENCE; BINDING SITE; CATALYSIS; COMPLEX FORMATION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; NONHUMAN; PRIORITY JOURNAL; REVIEW; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM;

BETA-LACTAMASES; BETA-LACTAMS; BINDING SITES; CATALYSIS; CATALYTIC DOMAIN; MODELS, MOLECULAR; SUBSTRATE SPECIFICITY; ZINC;

EID: 84903642660     PISSN: 17565901     EISSN: 1756591X     Source Type: Journal    
DOI: 10.1039/c4mt00066h     Document Type: Review

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