QM/MM studies of monozinc β-lactamase CphA suggest that the crystal structure of an enzyme-intermediate complex represents a minor pathway

Journal of the American Chemical Society

Volumn 132, Issue 51, 2010, Pages 17986-17988

  Wu, Shanshan ^a   Xu, Dingguo ^a   Guo, Hua ^b  

^a China   (China)

^b UNIVERSITY OF NEW MEXICO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERMEDIATE COMPLEX; LACTAMASES; REACTION MECHANISM;

CRYSTAL STRUCTURE; ENZYMES;

REACTION INTERMEDIATES;

BETA LACTAMASE; BIAPENEM;

ARTICLE; CATALYSIS; CHEMICAL REACTION; COMPLEX FORMATION; CRYSTAL STRUCTURE; ENZYME STRUCTURE; HYDROLYSIS; SIMULATION;

BACTERIAL PROTEINS; BETA-LACTAMASES; CRYSTALLOGRAPHY, X-RAY; QUANTUM THEORY; SUBSTRATE SPECIFICITY; ZINC;

EID: 78650620354     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja104241g     Document Type: Article

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