Evidence of adaptability in metal coordination geometry and active-site loop conformation among B1 metallo-β-lactamases

Biochemistry

Volumn 49, Issue 36, 2010, Pages 7930-7938

  González, Javier M ^a,d   Buschiazzo, Alejandro ^b,c   Vila, Alejandro J ^a  

^a UNIVERSIDAD NACIONAL DE ROSARIO   (Argentina)

^b INSTITUT PASTEUR DE MONTEVIDEO   (Uruguay)

^c INSTITUT PASTEUR   (France)

^d UNIVERSITY OF MARYLAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACILLUS CEREUS; BACTERIOLOGY; BINDING ENERGY; COMPUTATIONAL GEOMETRY; ENZYMES; LIGANDS; ZINC; ZINC COMPOUNDS;

BACTERIAL RESISTANCE; CATALYTIC MECHANISMS; CATALYTIC TURNOVER; COORDINATION GEOMETRY; HIGH-RESOLUTION STRUCTURES; HYDROLASES; LACTAMASES; LOOP CONFORMATION; METAL BINDING; METAL COORDINATION; METAL LIGANDS; METAL SITES; OXIDATION LEVEL; STRUCTURAL REARRANGEMENT;

METALS;

BACTERIAL ENZYME; BCII ENZYME; COBALT; CYSTEINE; METALLO BETA LACTAMASE; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; BETA LACTAMASE; LIGAND; METAL; ZINC;

ARTICLE; BACILLUS CEREUS; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME SPECIFICITY; OXIDATION; PRIORITY JOURNAL; X RAY CRYSTALLOGRAPHY; BINDING SITE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; KINETICS; METABOLISM; PROTEIN CONFORMATION;

BACILLUS CEREUS; BACTERIA (MICROORGANISMS);

BACILLUS CEREUS; BACTERIAL PROTEINS; BETA-LACTAMASES; BINDING SITES; CATALYSIS; CATALYTIC DOMAIN; COBALT; CYSTEINE; KINETICS; LIGANDS; METALS; MODELS, MOLECULAR; PROTEIN CONFORMATION; ZINC;

EID: 77956419437     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi100894r     Document Type: Article

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