Molecular dynamic simulations of the metallo-beta-lactamase from Bacteroides fragilis in the presence and absence of a tight-binding inhibitor

Journal of Molecular Modeling

Volumn 15, Issue 2, 2009, Pages 133-145

  Salsbury Jr , Freddie R ^a   Crowder, Michael W ^b   Kingsmore, Stephen F ^c   Huntley, James J A ^c  

^a WAKE FOREST UNIVERSITY   (United States)

^b MIAMI UNIVERSITY   (United States)

^c NATIONAL CENTER FOR GENOME RESOURCES   (United States)

Author keywords

Drug resistance; Long rang communication; Metallo beta lactamases; Molecular dynamics

Indexed keywords

ANTIBIOTIC AGENT; METALLO BETA LACTAMASE; ZINC BINDING PROTEIN;

ACCURACY; ANTIBIOTIC RESISTANCE; ARTICLE; BACTEROIDES FRAGILIS; COMPUTER SIMULATION; CONTROLLED STUDY; DRUG PROTEIN BINDING; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME STRUCTURE; LIGAND BINDING; MOLECULAR DYNAMICS; NONHUMAN; PLASTICITY; PRIORITY JOURNAL; PROTEIN FUNCTION;

BACTERIA (MICROORGANISMS); BACTEROIDES FRAGILIS;

EID: 58549090496     PISSN: 16102940     EISSN: 09485023     Source Type: Journal    
DOI: 10.1007/s00894-008-0410-0     Document Type: Article

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