Metallo-β-lactamases withstand low Zn(II) conditions by tuning metal-ligand interactions

Nature Chemical Biology

Volumn 8, Issue 8, 2012, Pages 698-700

  González, Javier M ^a,c   Meini, María Rocío ^a   Tomatis, Pablo E ^a   Martín, Francisco J Medrano ^b,c,d   Cricco, Julia A ^a   Vila, Alejandro J ^a  

^a UNIVERSIDAD NACIONAL DE ROSARIO   (Argentina)

^b LABORATÓRIO NACIONAL DE LUZ SÍNCROTRON   (Brazil)

^c UNIVERSITY OF MARYLAND   (United States)

^d CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAM ANTIBIOTIC; BETA LACTAMASE; CYSTEINE; IMIPENEM; LIGAND; METAL; ZINC;

ANTIBIOTIC RESISTANCE; ARTICLE; BINDING AFFINITY; BINDING KINETICS; BINDING SITE; CRYSTAL STRUCTURE; ESCHERICHIA COLI; GRAM NEGATIVE BACTERIUM; METAL BINDING; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; X RAY CRYSTALLOGRAPHY;

BACTERIA (MICROORGANISMS); NEGIBACTERIA;

EID: 84864290218     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.1005     Document Type: Article

References (23)

1. Crowder, M.W., Spencer, J. & Vila, A.J. Acc. Chem. Res. 39, 721-728 (2006).
2. Fisher, J.F., Meroueh, S.O. & Mobashery, S. Chem. Rev. 105, 395-424 (2005).
3. Fabiane, S.M. et al. Biochemistry 37, 12404-12411 (1998).
4. Orellano, E.G., Girardini, J.E., Cricco, J.A., Ceccarelli, E.A. & Vila, A.J. Biochemistry 37, 10173-10180 (1998).
5. Hu, Z., Peryannan, G., Bennett, B. & Crowder, M. J. Am. Chem. Soc. 130, 14207-14216 (2008).
6. Hawk, M.J. et al. J. Am. Chem. Soc. 131, 10753-10762 (2009).
7. Llarrull, L.I., Tioni, M.F. & Vila, A.J. J. Am. Chem. Soc. 130, 15842-15851 (2008).
8. Wommer, S. et al. J. Biol. Chem. 277, 24142-24147 (2002).
9. Tioni, M.F. et al. J. Am. Chem. Soc. 130, 15852-15863 (2008).
10. Badarau, A. & Page, M.I. Biochemistry 45, 11012-11020 (2006).
11. Carfi, A. et al. EMBO J. 14, 4914-4921 (1995).
12. Murphy, T.A. et al. J. Mol. Biol. 357, 890-903 (2006).
13. González, J.M., Buschiazzo, A. & Vila, A.J. Biochemistry 49, 7930-7938 (2010).
14. Davis, A.V. & O'Halloran, T.V. Nat. Chem. Biol. 4, 148-151 (2008).
15. Daiyasu, H., Osaka, K., Ishino, Y. & Toh, H. FEBS Lett. 503, 1-6 (2001).
16. Haruta, S. et al. Antimicrob. Agents Chemother. 44, 2304-2309 (2000).
17. Llarrull, L.I., Tioni, M.F., Kowalski, J., Bennett, B. & Vila, A.J. J. Biol. Chem. 282, 30586-30595 (2007).
18. Rasia, R.M. & Vila, A.J. J. Biol. Chem. 279, 26046-26051 (2004).
19. Simona, F. et al. J. Biol. Chem. 284, 28164-28171 (2009).
20. Jacquin, O. et al. J. Mol. Biol. 392, 1278-1291 (2009).
21. Outten, C.E. & O'Halloran, T.V. Science 292, 2488-2492 (2001).
22. Ma, Z., Jacobsen, F.E. & Giedroc, D.P. Chem. Rev. 109, 4644-4681 (2009).
23. Morán-Barrio, J., Limansky, A.S. & Viale, A.M. Antimicrob. Agents Chemother. 53, 2908-2917 (2009).