Direct evidence that the reaction intermediate of metallo-β-lactamase L1 is metal bound

Biochemistry

Volumn 44, Issue 3, 2005, Pages 1078-1087

  Garrity, James D ^a   Bennett, Brian ^b   Crowder, Michael W ^a  

^a MIAMI UNIVERSITY   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL REACTIONS; CRYSTALLOGRAPHY; ELECTRON SPIN RESONANCE SPECTROSCOPY; ENZYMES; MOLECULAR STRUCTURE; POSITIVE IONS; SUBSTRATES;

HYDROLYTIC REACTIONS; METAL-BOUND SPECIES; RAPID-FREEZE-QUENCH (RFQ) EPR SPECTRA; TIME-DEPENDENT ABSORPTION;

ORGANOMETALLICS;

BETA LACTAM ANTIBIOTIC; BETA LACTAMASE; CEFALOTIN; COBALT; MEROPENEM; METAL; METAL ION; METALLO BETA LACTAMASE L1; NITROCEFIN; PENICILLIN G; UNCLASSIFIED DRUG; ZINC;

ABSORPTION SPECTROSCOPY; ARTICLE; BINDING SITE; ELECTRON SPIN RESONANCE; ENZYME ANALYSIS; ENZYME KINETICS; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; HYDROLYSIS; PRIORITY JOURNAL; REACTION ANALYSIS; TIME; X RAY CRYSTALLOGRAPHY;

BACTERIAL PROTEINS; BETA-LACTAMASES; ELECTRON SPIN RESONANCE SPECTROSCOPY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; KINETICS; METALS; PROTEIN BINDING; SUBSTRATE SPECIFICITY;

EID: 12344323483     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi048385b     Document Type: Article

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