Mutational analysis of the two zinc-binding sites of the Bacillus cereus 569/H/9 metallo-β-lactamase

Biochemical Journal

Volumn 363, Issue 3, 2002, Pages 687-696

  De Seny, Dominique ^a   Prosperi Meys, Christelle ^a   Bebrone, Carine ^a   Rossolini, Gian Maria ^a   Page, Michael I ^a   Noel, Philippe ^a   Frère, Jean Marie ^a   Galleni, Moreno ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

Bacterial resistance; Dinuclear zinc enzymes; lactamase family

Indexed keywords

AMINO ACIDS; BACTERIA; CHEMICAL BONDS; ENZYMES; HYDROLYSIS; POLARIZATION; ZINC;

MUTATIONAL ANALYSIS;

BIOCHEMISTRY;

BETA LACTAM ANTIBIOTIC; BETA LACTAMASE; CARBONYL DERIVATIVE; HISTIDINE; LEWIS ACID; LIGAND; METALLO BETA LACTAMASE; MUTANT PROTEIN; SERINE; UNCLASSIFIED DRUG; WATER; ZINC;

AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ARTICLE; BACILLUS CEREUS; BINDING SITE; CATALYSIS; CIRCULAR DICHROISM; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; METAL BINDING; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN STABILITY; SITE DIRECTED MUTAGENESIS;

BACILLUS CEREUS; BACTERIA (MICROORGANISMS);

EID: 0036566439     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3630687     Document Type: Article

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