Obesity-mediated autophagy insufficiency exacerbates proteinuria-induced tubulointerstitial lesions

Journal of the American Society of Nephrology

Volumn 24, Issue 11, 2013, Pages 1769-1781

  Yamahara, Kosuke ^a   Kume, Shinji ^a   Koya, Daisuke ^b   Tanaka, Yuki ^a   Morita, Yoshikata ^a   Chin Kanasaki, Masami ^a   Araki, Hisazumi ^a   Isshiki, Keiji ^a   Araki, Shin Ichi ^a   Haneda, Masakazu ^c   Matsusaka, Taiji ^d   Kashiwagi, Atsunori ^a   Maegawa, Hiroshi ^a   Uzu, Takashi ^a  

^a SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^b KANAZAWA MEDICAL UNIVERSITY   (Japan)

^c ASAHIKAWA MEDICAL COLLEGE   (Japan)

^d TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; FATTY ACID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE ALPHA; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; PROTEIN; PROTEIN LC3; PROTEIN P62; S6 KINASE; SILENT INFORMATION REGULATOR PROTEIN 2; TUBERIN; TUBEROUS SCLEROSIS 1 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATG5 GENE; AUTOPHAGOSOME; AUTOPHAGY; CONTROLLED STUDY; DISEASE EXACERBATION; ENDOPLASMIC RETICULUM STRESS; GENE; GENE DELETION; HUMAN; HUMAN TISSUE; IMMUNOGLOBULIN A NEPHROPATHY; KIDNEY BIOPSY; KIDNEY INTERSTITIUM; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; KIDNEY TUBULE DAMAGE; LIPID DIET; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEINURIA; RENAL PROTECTION;

EID: 84887070613     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2012111080     Document Type: Article

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