Effects of 4-phenylbutyric acid on the process and development of diabetic nephropathy induced in rats by streptozotocin: Regulation of endoplasmic reticulum stress-oxidative activation

Toxicology and Applied Pharmacology

Volumn 246, Issue 1-2, 2010, Pages 49-57

  Luo, Zhi Feng ^a   Feng, Bing ^a   Mu, Jiao ^a   Qi, Wei ^a   Zeng, Wei ^a   Guo, Yan Hong ^a   Pang, Qi ^a   Ye, Zi Lin ^a   Liu, Li ^a   Yuan, Fa Huan ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

4 phenylbutyric acid; Diabetic nephropathy; Endoplasmic reticulum stress; Inflammation; Oxidative stress

Indexed keywords

3 NITROTYROSINE; 4 PHENYLBUTYRIC ACID; ENZYME; HYDROXYPROLINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INOSITOL REQUIRING ENZYME 1ALPHA; MALONALDEHYDE; PROTEIN P47; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; STREPTOZOCIN; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; ENZYME PHOSPHORYLATION; MALE; NONHUMAN; OXIDATIVE STRESS; RAT; REGULATORY MECHANISM;

ANIMALS; ANTIOXIDANTS; BLOOD UREA NITROGEN; CREATININE; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHIES; ENDOPLASMIC RETICULUM; HYDROXYPROLINE; KIDNEY; MALE; MALONDIALDEHYDE; NADPH OXIDASE; OXIDATIVE STRESS; PHENYLBUTYRATES; PROTEINURIA; RATS; RATS, SPRAGUE-DAWLEY; SUPEROXIDE DISMUTASE;

RATTUS;

EID: 77953719527     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2010.04.005     Document Type: Article

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