Indoxyl sulfate inhibits proliferation of human proximal tubular cells via endoplasmic reticulum stress

American Journal of Physiology - Renal Physiology

Volumn 299, Issue 3, 2010, Pages

  Kawakami, Takahisa ^a   Inagi, Reiko ^a   Wada, Takehiko ^a   Tanaka, Tetsuhiro ^a   Fujita, Toshiro ^a   Nangaku, Masaomi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Chronic kidney disease; Cyclin dependent kinase inhibitor; Inflammatory cytokine; Tubular injury; Uremic toxin

Indexed keywords

AST 120; CARBON; CDKN1A PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; DDIT3 PROTEIN, HUMAN; DDIT3 PROTEIN, RAT; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INDICAN; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; OXIDE;

ANIMAL; CELL DEATH; CELL LINE; CELL PROLIFERATION; CHRONIC DISEASE; CYTOLOGY; DISEASE MODEL; DRUG EFFECTS; ENDOPLASMIC RETICULUM; HUMAN; KIDNEY DISEASE; KIDNEY PROXIMAL TUBULE; MALE; METABOLISM; NEPHRECTOMY; PHYSIOLOGICAL STRESS; PHYSIOLOGY; RAT; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALS; CARBON; CELL DEATH; CELL LINE; CELL PROLIFERATION; CHRONIC DISEASE; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DISEASE MODELS, ANIMAL; ENDOPLASMIC RETICULUM; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; INDICAN; INTERLEUKIN-6; KIDNEY DISEASES; KIDNEY TUBULES, PROXIMAL; MALE; NEPHRECTOMY; OXIDES; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL; TRANSCRIPTION FACTOR CHOP;

EID: 77956453961     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00659.2009     Document Type: Article

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