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Volumn 5, Issue 2, 2014, Pages 385-414

The little fly that could: Wizardry and artistry of Drosophila genomics

Author keywords

Drosophila; Genetics; Genomics

Indexed keywords

FRIZZLED PROTEIN; NOTCH RECEPTOR; TRANSCRIPTION FACTOR PAX6;

EID: 84902251597     PISSN: None     EISSN: 20734425     Source Type: Journal    
DOI: 10.3390/genes5020385     Document Type: Review
Times cited : (9)

References (218)
  • 2
    • 0031000180 scopus 로고    scopus 로고
    • The first genome from the third domain of life
    • Clayton, R.A.; White, O.; Ketchum, K.A.; Venter, J.C. The first genome from the third domain of life. Nature 1997, 387, 459-462.
    • (1997) Nature , vol.387 , pp. 459-462
    • Clayton, R.A.1    White, O.2    Ketchum, K.A.3    Venter, J.C.4
  • 3
    • 0032509302 scopus 로고    scopus 로고
    • Genome sequence of the nematode C. elegans: A platform for investigating biology
    • C. elegans Sequencing Consortium
    • C. elegans Sequencing Consortium. Genome sequence of the nematode C. elegans: A platform for investigating biology. Science 1998, 282, 2012-2018.
    • (1998) Science , vol.282 , pp. 2012-2018
  • 5
    • 0018240421 scopus 로고
    • A gene complex controlling segmentation in drosophila
    • Lewis, E.B. A gene complex controlling segmentation in drosophila. Nature 1978, 276, 565-570.
    • (1978) Nature , vol.276 , pp. 565-570
    • Lewis, E.B.1
  • 6
    • 0019133661 scopus 로고
    • Mutations affecting segment number and polarity in drosophila
    • Nusslein-Volhard, C.; Wieschaus, E. Mutations affecting segment number and polarity in drosophila. Nature 1980, 287, 795-801.
    • (1980) Nature , vol.287 , pp. 795-801
    • Nusslein-Volhard, C.1    Wieschaus, E.2
  • 7
    • 0022963679 scopus 로고
    • Homeotic genes and the homeobox
    • Gehring, W.J.; Hiromi, Y. Homeotic genes and the homeobox. Annu. Rev. Genet. 1986, 20, 147-173.
    • (1986) Annu. Rev. Genet , vol.20 , pp. 147-173
    • Gehring, W.J.1    Hiromi, Y.2
  • 8
    • 0028026651 scopus 로고
    • Homeobox genes: Their function in drosophila segmentation and pattern formation
    • Lawrence, P.A.; Morata, G. Homeobox genes: Their function in drosophila segmentation and pattern formation. Cell 1994, 78, 181-189.
    • (1994) Cell , vol.78 , pp. 181-189
    • Lawrence, P.A.1    Morata, G.2
  • 9
    • 0027953771 scopus 로고
    • Hox genes in vertebrate development
    • Krumlauf, R. Hox genes in vertebrate development. Cell 1994, 78, 191-201.
    • (1994) Cell , vol.78 , pp. 191-201
    • Krumlauf, R.1
  • 10
    • 0027965633 scopus 로고
    • Homology of the eyeless gene of drosophila to the small eye gene in mice and aniridia in humans
    • Quiring, R.; Walldorf, U.; Kloter, U.; Gehring, W.J. Homology of the eyeless gene of drosophila to the small eye gene in mice and aniridia in humans. Science 1994, 265, 785-789.
    • (1994) Science , vol.265 , pp. 785-789
    • Quiring, R.1    Walldorf, U.2    Kloter, U.3    Gehring, W.J.4
  • 13
    • 0031819408 scopus 로고    scopus 로고
    • Eyeless initiates the expression of both sine oculis and eyes absent during drosophila compound eye development
    • Halder, G.; Callaerts, P.; Flister, S.; Walldorf, U.; Kloter, U.; Gehring, W.J. Eyeless initiates the expression of both sine oculis and eyes absent during drosophila compound eye development. Development 1998, 125, 2181-2191.
    • (1998) Development , vol.125 , pp. 2181-2191
    • Halder, G.1    Callaerts, P.2    Flister, S.3    Walldorf, U.4    Kloter, U.5    Gehring, W.J.6
  • 14
    • 60149107489 scopus 로고    scopus 로고
    • The sine oculis homeobox (six) family of transcription factors as regulators of development and disease
    • Kumar, J.P. The sine oculis homeobox (six) family of transcription factors as regulators of development and disease. Cell. Mol. Life Sci. 2009, 66, 565-583.
    • (2009) Cell. Mol. Life Sci , vol.66 , pp. 565-583
    • Kumar, J.P.1
  • 15
    • 0028275740 scopus 로고
    • Atonal is the proneural gene for drosophila photoreceptors
    • Jarman, A.P.; Grell, E.H.; Ackerman, L.; Jan, L.Y.; Jan, Y.N. Atonal is the proneural gene for drosophila photoreceptors. Nature 1994, 369, 398-400.
    • (1994) Nature , vol.369 , pp. 398-400
    • Jarman, A.P.1    Grell, E.H.2    Ackerman, L.3    Jan, L.Y.4    Jan, Y.N.5
  • 16
    • 0027233365 scopus 로고
    • Atonal is a proneural gene that directs chordotonal organ formation in the drosophila peripheral nervous system
    • Jarman, A.P.; Grau, Y.; Jan, L.Y.; Jan, Y.N. Atonal is a proneural gene that directs chordotonal organ formation in the drosophila peripheral nervous system. Cell 1993, 73, 1307-1321.
    • (1993) Cell , vol.73 , pp. 1307-1321
    • Jarman, A.P.1    Grau, Y.2    Jan, L.Y.3    Jan, Y.N.4
  • 17
    • 0034926798 scopus 로고    scopus 로고
    • Math5 is required for retinal ganglion cell and optic nerve formation
    • Brown, N.L.; Patel, S.; Brzezinski, J.; Glaser, T. Math5 is required for retinal ganglion cell and optic nerve formation. Development 2001, 128, 2497-2508.
    • (2001) Development , vol.128 , pp. 2497-2508
    • Brown, N.L.1    Patel, S.2    Brzezinski, J.3    Glaser, T.4
  • 19
    • 0027096741 scopus 로고
    • The drosophila hedgehog gene is expressed specifically in posterior compartment cells and is a target of engrailed regulation
    • Tabata, T.; Eaton, S.; Kornberg, T.B. The drosophila hedgehog gene is expressed specifically in posterior compartment cells and is a target of engrailed regulation. Genes Dev. 1992, 6, 2635-2645.
    • (1992) Genes Dev , vol.6 , pp. 2635-2645
    • Tabata, T.1    Eaton, S.2    Kornberg, T.B.3
  • 20
    • 0026783674 scopus 로고
    • Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog
    • Lee, J.J.; von Kessler, D.P.; Parks, S.; Beachy, P.A. Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog. Cell 1992, 71, 33-50.
    • (1992) Cell , vol.71 , pp. 33-50
    • Lee, J.J.1    von Kessler, D.P.2    Parks, S.3    Beachy, P.A.4
  • 21
    • 0024468746 scopus 로고
    • The drosophila patched gene encodes a putative membrane protein required for segmental patterning
    • Hooper, J.E.; Scott, M.P. The drosophila patched gene encodes a putative membrane protein required for segmental patterning. Cell 1989, 59, 751-765.
    • (1989) Cell , vol.59 , pp. 751-765
    • Hooper, J.E.1    Scott, M.P.2
  • 22
    • 0024440611 scopus 로고
    • A protein with several possible membrane-spanning domains encoded by the drosophila segment polarity gene patched
    • Nakano, Y.; Guerrero, I.; Hidalgo, A.; Taylor, A.; Whittle, J.R.; Ingham, P.W. A protein with several possible membrane-spanning domains encoded by the drosophila segment polarity gene patched. Nature 1989, 341, 508-513.
    • (1989) Nature , vol.341 , pp. 508-513
    • Nakano, Y.1    Guerrero, I.2    Hidalgo, A.3    Taylor, A.4    Whittle, J.R.5    Ingham, P.W.6
  • 24
    • 0029948270 scopus 로고    scopus 로고
    • Biochemical evidence that patched is the hedgehog receptor
    • Marigo, V.; Davey, R.A.; Zuo, Y.; Cunningham, J.M.; Tabin, C.J. Biochemical evidence that patched is the hedgehog receptor. Nature 1996, 384, 176-179.
    • (1996) Nature , vol.384 , pp. 176-179
    • Marigo, V.1    Davey, R.A.2    Zuo, Y.3    Cunningham, J.M.4    Tabin, C.J.5
  • 26
    • 0027070855 scopus 로고
    • Wingless signaling acts through zeste-white 3, the drosophila homolog of glycogen synthase kinase-3, to regulate engrailed and establish cell fate
    • Siegfried, E.; Chou, T.B.; Perrimon, N. Wingless signaling acts through zeste-white 3, the drosophila homolog of glycogen synthase kinase-3, to regulate engrailed and establish cell fate. Cell 1992, 71, 1167-1179.
    • (1992) Cell , vol.71 , pp. 1167-1179
    • Siegfried, E.1    Chou, T.B.2    Perrimon, N.3
  • 28
    • 0031043238 scopus 로고    scopus 로고
    • Pangolin encodes a lef-1 homologue that acts downstream of armadillo to transduce the wingless signal in drosophila
    • Brunner, E.; Peter, O.; Schweizer, L.; Basler, K. Pangolin encodes a lef-1 homologue that acts downstream of armadillo to transduce the wingless signal in drosophila. Nature 1997, 385, 829-833.
    • (1997) Nature , vol.385 , pp. 829-833
    • Brunner, E.1    Peter, O.2    Schweizer, L.3    Basler, K.4
  • 29
    • 0026955974 scopus 로고
    • The genetic control of tissue polarity in drosophila
    • Adler, P.N. The genetic control of tissue polarity in drosophila. BioEssays 1992, 14, 735-741.
    • (1992) BioEssays , vol.14 , pp. 735-741
    • Adler, P.N.1
  • 30
    • 81955160697 scopus 로고    scopus 로고
    • Cell flow and tissue polarity patterns
    • Eaton, S.; Julicher, F. Cell flow and tissue polarity patterns. Curr. Opin. Genet. Dev. 2011, 21, 747-752.
    • (2011) Curr. Opin. Genet. Dev , vol.21 , pp. 747-752
    • Eaton, S.1    Julicher, F.2
  • 31
    • 0022289842 scopus 로고
    • Nucleotide sequence from the neurogenic locus notch implies a gene product that shares homology with proteins containing egf-like repeats
    • Wharton, K.A.; Johansen, K.M.; Xu, T.; Artavanis-Tsakonas, S. Nucleotide sequence from the neurogenic locus notch implies a gene product that shares homology with proteins containing egf-like repeats. Cell 1985, 43, 567-581.
    • (1985) Cell , vol.43 , pp. 567-581
    • Wharton, K.A.1    Johansen, K.M.2    Xu, T.3    Artavanis-Tsakonas, S.4
  • 33
    • 0033617522 scopus 로고    scopus 로고
    • Notch signaling: Cell fate control and signal integration in development
    • Artavanis-Tsakonas, S.; Rand, M.D.; Lake, R.J. Notch signaling: Cell fate control and signal integration in development. Science 1999, 284, 770-776.
    • (1999) Science , vol.284 , pp. 770-776
    • Artavanis-Tsakonas, S.1    Rand, M.D.2    Lake, R.J.3
  • 34
    • 0042232429 scopus 로고    scopus 로고
    • Hippo encodes a STE-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts
    • Wu, S.; Huang, J.; Dong, J.; Pan, D. Hippo encodes a STE-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts. Cell 2003, 114, 445-456.
    • (2003) Cell , vol.114 , pp. 445-456
    • Wu, S.1    Huang, J.2    Dong, J.3    Pan, D.4
  • 35
    • 0042733354 scopus 로고    scopus 로고
    • The drosophila mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis
    • Harvey, K.F.; Pfleger, C.M.; Hariharan, I.K. The drosophila mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis. Cell 2003, 114, 457-467.
    • (2003) Cell , vol.114 , pp. 457-467
    • Harvey, K.F.1    Pfleger, C.M.2    Hariharan, I.K.3
  • 36
    • 0141616617 scopus 로고    scopus 로고
    • Hippo promotes proliferation arrest and apoptosis in the salvador/warts pathway
    • Udan, R.S.; Kango-Singh, M.; Nolo, R.; Tao, C.; Halder, G. Hippo promotes proliferation arrest and apoptosis in the salvador/warts pathway. Nat. Cell Biol. 2003, 5, 914-920.
    • (2003) Nat. Cell Biol , vol.5 , pp. 914-920
    • Udan, R.S.1    Kango-Singh, M.2    Nolo, R.3    Tao, C.4    Halder, G.5
  • 37
    • 0034176088 scopus 로고    scopus 로고
    • Modeling human neurodegenerative diseases in drosophila: On a wing and a prayer
    • Fortini, M.E.; Bonini, N.M. Modeling human neurodegenerative diseases in drosophila: On a wing and a prayer. Trends Genet. 2000, 16, 161-167.
    • (2000) Trends Genet , vol.16 , pp. 161-167
    • Fortini, M.E.1    Bonini, N.M.2
  • 38
    • 77949899075 scopus 로고    scopus 로고
    • Flightless flies: Drosophila models of neuromuscular disease
    • Lloyd, T.E.; Taylor, J.P. Flightless flies: Drosophila models of neuromuscular disease. Ann. N. Y. Acad. Sci. 2010, 1184, e1-e20.
    • (2010) Ann. N. Y. Acad. Sci , vol.1184
    • Lloyd, T.E.1    Taylor, J.P.2
  • 39
    • 0033621538 scopus 로고    scopus 로고
    • Drosophila in cancer research. An expanding role
    • Potter, C.J.; Turenchalk, G.S.; Xu, T. Drosophila in cancer research. An expanding role. Trends Genet. 2000, 16, 33-39.
    • (2000) Trends Genet , vol.16 , pp. 33-39
    • Potter, C.J.1    Turenchalk, G.S.2    Xu, T.3
  • 40
    • 0032168160 scopus 로고    scopus 로고
    • Polyglutamine-expanded human huntingtin transgenes induce degeneration of drosophila photoreceptor neurons
    • Jackson, G.R.; Salecker, I.; Dong, X.; Yao, X.; Arnheim, N.; Faber, P.W.; MacDonald, M.E.; Zipursky, S.L. Polyglutamine-expanded human huntingtin transgenes induce degeneration of drosophila photoreceptor neurons. Neuron 1998, 21, 633-642.
    • (1998) Neuron , vol.21 , pp. 633-642
    • Jackson, G.R.1    Salecker, I.2    Dong, X.3    Yao, X.4    Arnheim, N.5    Faber, P.W.6    Macdonald, M.E.7    Zipursky, S.L.8
  • 41
    • 18544392423 scopus 로고    scopus 로고
    • Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in drosophila
    • Warrick, J.M.; Paulson, H.L.; Gray-Board, G.L.; Bui, Q.T.; Fischbeck, K.H.; Pittman, R.N.; Bonini, N.M. Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in drosophila. Cell 1998, 93, 939-949.
    • (1998) Cell , vol.93 , pp. 939-949
    • Warrick, J.M.1    Paulson, H.L.2    Gray-Board, G.L.3    Bui, Q.T.4    Fischbeck, K.H.5    Pittman, R.N.6    Bonini, N.M.7
  • 43
    • 0025664016 scopus 로고
    • Identification, secretion, and neural expression of appl, a drosophila protein similar to human amyloid protein precursor
    • Luo, L.Q.; Martin-Morris, L.E.; White, K. Identification, secretion, and neural expression of appl, a drosophila protein similar to human amyloid protein precursor. J. Neurosci. 1990, 10, 3849-3861.
    • (1990) J. Neurosci , vol.10 , pp. 3849-3861
    • Luo, L.Q.1    Martin-Morris, L.E.2    White, K.3
  • 44
    • 0026783241 scopus 로고
    • Human amyloid precursor protein ameliorates behavioral deficit of flies deleted for appl gene
    • Luo, L.; Tully, T.; White, K. Human amyloid precursor protein ameliorates behavioral deficit of flies deleted for appl gene. Neuron 1992, 9, 595-605.
    • (1992) Neuron , vol.9 , pp. 595-605
    • Luo, L.1    Tully, T.2    White, K.3
  • 45
    • 0033588991 scopus 로고    scopus 로고
    • Apoptotic activities of wild-type and alzheimer's disease-related mutant presenilins in drosophila melanogaster
    • Ye, Y.; Fortini, M.E. Apoptotic activities of wild-type and alzheimer's disease-related mutant presenilins in drosophila melanogaster. J. Cell Biol. 1999, 146, 1351-1364.
    • (1999) J. Cell Biol , vol.146 , pp. 1351-1364
    • Ye, Y.1    Fortini, M.E.2
  • 47
    • 0034704752 scopus 로고    scopus 로고
    • A drosophila model of parkinson's disease
    • Feany, M.B.; Bender, W.W. A drosophila model of parkinson's disease. Nature 2000, 404, 394-398.
    • (2000) Nature , vol.404 , pp. 394-398
    • Feany, M.B.1    Bender, W.W.2
  • 48
    • 20344369560 scopus 로고    scopus 로고
    • Increased glutathione s-transferase activity rescues dopaminergic neuron loss in a drosophila model of parkinson's disease
    • Whitworth, A.J.; Theodore, D.A.; Greene, J.C.; Benes, H.; Wes, P.D.; Pallanck, L.J. Increased glutathione s-transferase activity rescues dopaminergic neuron loss in a drosophila model of parkinson's disease. Proc. Natl. Acad. Sci. USA 2005, 102, 8024-8029.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 8024-8029
    • Whitworth, A.J.1    Theodore, D.A.2    Greene, J.C.3    Benes, H.4    Wes, P.D.5    Pallanck, L.J.6
  • 50
    • 84889826574 scopus 로고    scopus 로고
    • Defects in synapse structure and function precede motor neuron degeneration in drosophila models of fus-related als
    • Shahidullah, M.; Le Marchand, S.J.; Fei, H.; Zhang, J.; Pandey, U.B.; Dalva, M.B.; Pasinelli, P.; Levitan, I.B. Defects in synapse structure and function precede motor neuron degeneration in drosophila models of fus-related als. J. Neurosci. 2013, 33, 19590-19598.
    • (2013) J. Neurosci , vol.33 , pp. 19590-19598
    • Shahidullah, M.1    Le Marchand, S.J.2    Fei, H.3    Zhang, J.4    Pandey, U.B.5    Dalva, M.B.6    Pasinelli, P.7    Levitan, I.B.8
  • 51
    • 30644469248 scopus 로고    scopus 로고
    • Dystrophin is required for appropriate retrograde control of neurotransmitter release at the drosophila neuromuscular junction
    • Van der Plas, M.C.; Pilgram, G.S.; Plomp, J.J.; de Jong, A.; Fradkin, L.G.; Noordermeer, J.N. Dystrophin is required for appropriate retrograde control of neurotransmitter release at the drosophila neuromuscular junction. J. Neurosci. 2006, 26, 333-344.
    • (2006) J. Neurosci , vol.26 , pp. 333-344
    • Van der Plas, M.C.1    Pilgram, G.S.2    Plomp, J.J.3    de Jong, A.4    Fradkin, L.G.5    Noordermeer, J.N.6
  • 52
    • 0032511188 scopus 로고    scopus 로고
    • Ethanol intoxication in drosophila: Genetic and pharmacological evidence for regulation by the camp signaling pathway
    • Moore, M.S.; DeZazzo, J.; Luk, A.Y.; Tully, T.; Singh, C.M.; Heberlein, U. Ethanol intoxication in drosophila: Genetic and pharmacological evidence for regulation by the camp signaling pathway. Cell 1998, 93, 997-1007.
    • (1998) Cell , vol.93 , pp. 997-1007
    • Moore, M.S.1    Dezazzo, J.2    Luk, A.Y.3    Tully, T.4    Singh, C.M.5    Heberlein, U.6
  • 54
    • 0032518346 scopus 로고    scopus 로고
    • Stereotypic behavioral responses to free-base cocaine and the development of behavioral sensitization in drosophila
    • McClung, C.; Hirsh, J. Stereotypic behavioral responses to free-base cocaine and the development of behavioral sensitization in drosophila. Curr. Biol. 1998, 8, 109-112.
    • (1998) Curr. Biol , vol.8 , pp. 109-112
    • McClung, C.1    Hirsh, J.2
  • 56
    • 34548847172 scopus 로고    scopus 로고
    • Diabetic larvae and obese flies-emerging studies of metabolism in drosophila
    • Baker, K.D.; Thummel, C.S. Diabetic larvae and obese flies-emerging studies of metabolism in drosophila. Cell Metab. 2007, 6, 257-266.
    • (2007) Cell Metab , vol.6 , pp. 257-266
    • Baker, K.D.1    Thummel, C.S.2
  • 58
    • 84555195154 scopus 로고    scopus 로고
    • A drosophila asthma model-What the fly tells us about inflammatory diseases of the lung
    • Roeder, T.; Isermann, K.; Kallsen, K.; Uliczka, K.; Wagner, C. A drosophila asthma model-What the fly tells us about inflammatory diseases of the lung. Adv. Exp. Med. Biol. 2012, 710, 37-47.
    • (2012) Adv. Exp. Med. Biol , vol.710 , pp. 37-47
    • Roeder, T.1    Isermann, K.2    Kallsen, K.3    Uliczka, K.4    Wagner, C.5
  • 59
    • 0028929414 scopus 로고
    • Identifying tumor suppressors in genetic mosaics: The drosophila lats gene encodes a putative protein kinase
    • Xu, T.; Wang, W.; Zhang, S.; Stewart, R.A.; Yu, W. Identifying tumor suppressors in genetic mosaics: The drosophila lats gene encodes a putative protein kinase. Development 1995, 121, 1053-1063.
    • (1995) Development , vol.121 , pp. 1053-1063
    • Xu, T.1    Wang, W.2    Zhang, S.3    Stewart, R.A.4    Yu, W.5
  • 60
    • 0242666126 scopus 로고    scopus 로고
    • A genetic screen in drosophila for metastatic behavior
    • Pagliarini, R.A.; Xu, T. A genetic screen in drosophila for metastatic behavior. Science 2003, 302, 1227-1231.
    • (2003) Science , vol.302 , pp. 1227-1231
    • Pagliarini, R.A.1    Xu, T.2
  • 61
    • 56749171402 scopus 로고    scopus 로고
    • Drosophila asymmetric division, polarity and cancer
    • Januschke, J.; Gonzalez, C. Drosophila asymmetric division, polarity and cancer. Oncogene 2008, 27, 6994-7002.
    • (2008) Oncogene , vol.27 , pp. 6994-7002
    • Januschke, J.1    Gonzalez, C.2
  • 62
    • 23144434969 scopus 로고    scopus 로고
    • Using drosophila melanogaster to map human cancer pathways
    • Brumby, A.M.; Richardson, H.E. Using drosophila melanogaster to map human cancer pathways. Nat. Rev. Cancer 2005, 5, 626-639.
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 626-639
    • Brumby, A.M.1    Richardson, H.E.2
  • 63
    • 30644469503 scopus 로고    scopus 로고
    • Drosophila models for cancer research
    • Vidal, M.; Cagan, R.L. Drosophila models for cancer research. Curr. Opin. Genet. Dev. 2006, 16, 10-16.
    • (2006) Curr. Opin. Genet. Dev , vol.16 , pp. 10-16
    • Vidal, M.1    Cagan, R.L.2
  • 64
    • 81455136725 scopus 로고    scopus 로고
    • Modeling tumor invasion and metastasis in drosophila
    • Miles, W.O.; Dyson, N.J.; Walker, J.A. Modeling tumor invasion and metastasis in drosophila. Dis. Models Mech. 2011, 4, 753-761.
    • (2011) Dis. Models Mech , vol.4 , pp. 753-761
    • Miles, W.O.1    Dyson, N.J.2    Walker, J.A.3
  • 65
    • 84875412051 scopus 로고    scopus 로고
    • Drosophila melanogaster: A model and a tool to investigate malignancy and identify new therapeutics
    • Gonzalez, C. Drosophila melanogaster: A model and a tool to investigate malignancy and identify new therapeutics. Nat. Rev. Cancer 2013, 13, 172-183.
    • (2013) Nat. Rev. Cancer , vol.13 , pp. 172-183
    • Gonzalez, C.1
  • 66
    • 37249016357 scopus 로고    scopus 로고
    • Analysis of drosophila species genome size and satellite DNA content reveals significant differences among strains as well as between species
    • Bosco, G.; Campbell, P.; Leiva-Neto, J.T.; Markow, T.A. Analysis of drosophila species genome size and satellite DNA content reveals significant differences among strains as well as between species. Genetics 2007, 177, 1277-1290.
    • (2007) Genetics , vol.177 , pp. 1277-1290
    • Bosco, G.1    Campbell, P.2    Leiva-Neto, J.T.3    Markow, T.A.4
  • 72
    • 0012253746 scopus 로고    scopus 로고
    • Computational analysis of core promoters in the drosophila genome
    • doi:10.1186/gb-2002-3-12-research0087
    • Ohler, U.; Liao, G.C.; Niemann, H.; Rubin, G.M. Computational analysis of core promoters in the drosophila genome. Genome Biol. 2002, doi:10.1186/gb-2002-3-12-research0087.
    • (2002) Genome Biol
    • Ohler, U.1    Liao, G.C.2    Niemann, H.3    Rubin, G.M.4
  • 77
    • 0034022596 scopus 로고    scopus 로고
    • Genie-Gene finding in drosophila melanogaster
    • Reese, M.G.; Kulp, D.; Tammana, H.; Haussler, D. Genie-Gene finding in drosophila melanogaster. Genome Res. 2000, 10, 529-538.
    • (2000) Genome Res , vol.10 , pp. 529-538
    • Reese, M.G.1    Kulp, D.2    Tammana, H.3    Haussler, D.4
  • 84
    • 78651255620 scopus 로고    scopus 로고
    • Modeling the evolution of regulatory elements by simultaneous detection and alignment with phylogenetic pair hmms
    • Majoros, W.H.; Ohler, U. Modeling the evolution of regulatory elements by simultaneous detection and alignment with phylogenetic pair hmms. PLoS Comput. Biol. 2010, 6, e1001037.
    • (2010) PLoS Comput. Biol , vol.6
    • Majoros, W.H.1    Ohler, U.2
  • 85
    • 77955877436 scopus 로고    scopus 로고
    • An alignment-free method to identify candidate orthologous enhancers in multiple drosophila genomes
    • Arunachalam, M.; Jayasurya, K.; Tomancak, P.; Ohler, U. An alignment-free method to identify candidate orthologous enhancers in multiple drosophila genomes. Bioinformatics 2010, 26, 2109-2115.
    • (2010) Bioinformatics , vol.26 , pp. 2109-2115
    • Arunachalam, M.1    Jayasurya, K.2    Tomancak, P.3    Ohler, U.4
  • 86
    • 77955015475 scopus 로고    scopus 로고
    • Robust target gene discovery through transcriptome perturbations and genome-wide enhancer predictions in drosophila uncovers a regulatory basis for sensory specification
    • Aerts, S.; Quan, X.J.; Claeys, A.; Naval Sanchez, M.; Tate, P.; Yan, J.; Hassan, B.A. Robust target gene discovery through transcriptome perturbations and genome-wide enhancer predictions in drosophila uncovers a regulatory basis for sensory specification. PLoS Biol. 2010, 8, e1000435.
    • (2010) PLoS Biol , vol.8
    • Aerts, S.1    Quan, X.J.2    Claeys, A.3    Naval, S.M.4    Tate, P.5    Yan, J.6    Hassan, B.A.7
  • 87
    • 0035230102 scopus 로고    scopus 로고
    • Quantitative trait loci in drosophila
    • Mackay, T.F. Quantitative trait loci in drosophila. Nat. Rev. Genet. 2001, 2, 11-20.
    • (2001) Nat. Rev. Genet , vol.2 , pp. 11-20
    • Mackay, T.F.1
  • 93
    • 84862011012 scopus 로고    scopus 로고
    • Genome-wide association for sensitivity to chronic oxidative stress in drosophila melanogaster
    • Jordan, K.W.; Craver, K.L.; Magwire, M.M.; Cubilla, C.E.; Mackay, T.F.; Anholt, R.R. Genome-wide association for sensitivity to chronic oxidative stress in drosophila melanogaster. PLoS One 2012, 7, e38722.
    • (2012) PLoS One , vol.7 , pp. 38722
    • Jordan, K.W.1    Craver, K.L.2    Magwire, M.M.3    Cubilla, C.E.4    Mackay, T.F.5    Anholt, R.R.6
  • 94
    • 84869874747 scopus 로고    scopus 로고
    • Nuclear genomic control of naturally occurring variation in mitochondrial function in drosophila melanogaster
    • doi:10.1186/1471-2164-13-659
    • Jumbo-Lucioni, P.; Bu, S.; Harbison, S.T.; Slaughter, J.C.; Mackay, T.F.; Moellering, D.R.; de Luca, M. Nuclear genomic control of naturally occurring variation in mitochondrial function in drosophila melanogaster. BMC Genomics 2012, doi:10.1186/1471-2164-13-659.
    • (2012) BMC Genomics
    • Jumbo-Lucioni, P.1    Bu, S.2    Harbison, S.T.3    Slaughter, J.C.4    Mackay, T.F.5    Moellering, D.R.6    de Luca, M.7
  • 95
    • 84870676892 scopus 로고    scopus 로고
    • Genome-wide association studies reveal a simple genetic basis of resistance to naturally coevolving viruses in drosophila melanogaster
    • Magwire, M.M.; Fabian, D.K.; Schweyen, H.; Cao, C.; Longdon, B.; Bayer, F.; Jiggins, F.M. Genome-wide association studies reveal a simple genetic basis of resistance to naturally coevolving viruses in drosophila melanogaster. PLoS Genet. 2012, 8, e1003057.
    • (2012) PLoS Genet , vol.8 , pp. 1003057
    • Magwire, M.M.1    Fabian, D.K.2    Schweyen, H.3    Cao, C.4    Longdon, B.5    Bayer, F.6    Jiggins, F.M.7
  • 96
    • 84876973398 scopus 로고    scopus 로고
    • Genome-wide association study of sleep in drosophila melanogaster
    • doi:10.1186/1471-2164-14-281
    • Harbison, S.T.; McCoy, L.J.; Mackay, T.F. Genome-wide association study of sleep in drosophila melanogaster. BMC Genomics 2013, doi:10.1186/1471-2164-14-281.
    • (2013) BMC Genomics
    • Harbison, S.T.1    McCoy, L.J.2    Mackay, T.F.3
  • 97
    • 84863880314 scopus 로고    scopus 로고
    • Properties and power of the drosophila synthetic population resource for the routine dissection of complex traits
    • King, E.G.; Macdonald, S.J.; Long, A.D. Properties and power of the drosophila synthetic population resource for the routine dissection of complex traits. Genetics 2012, 191, 935-949.
    • (2012) Genetics , vol.191 , pp. 935-949
    • King, E.G.1    Macdonald, S.J.2    Long, A.D.3
  • 98
    • 7444260846 scopus 로고    scopus 로고
    • The encode (encyclopedia of DNA elements) project
    • ENCODE Project Consortium
    • ENCODE Project Consortium. The encode (encyclopedia of DNA elements) project. Science 2004, 306, 636-640.
    • (2004) Science , vol.306 , pp. 636-640
  • 100
    • 78650331647 scopus 로고    scopus 로고
    • Identification of functional elements and regulatory circuits by drosophila modencode
    • 100. modENCODE Consortium;
    • ModENCODE Consortium; Roy, S.; Ernst, J.; Kharchenko, P.V.; Kheradpour, P.; Negre, N.; Eaton, M.L.; Landolin, J.M.; Bristow, C.A.; Ma, L., et al. Identification of functional elements and regulatory circuits by drosophila modencode. Science 2010, 330, 1787-1797.
    • (2010) Science , vol.330 , pp. 1787-1797
    • Roy, S.1    Ernst, J.2    Kharchenko, P.V.3    Kheradpour, P.4    Negre, N.5    Eaton, M.L.6    Landolin, J.M.7    Bristow, C.A.8    Ma, L.9
  • 104
    • 0019967916 scopus 로고
    • Transposition of cloned p elements into drosophila germ line chromosomes
    • Spradling, A.C.; Rubin, G.M. Transposition of cloned p elements into drosophila germ line chromosomes. Science 1982, 218, 341-347.
    • (1982) Science , vol.218 , pp. 341-347
    • Spradling, A.C.1    Rubin, G.M.2
  • 105
    • 0020462608 scopus 로고
    • Molecular cloning of sequences from a drosophila RNA polymerase ii locus by p element transposon tagging
    • Searles, L.L.; Jokerst, R.S.; Bingham, P.M.; Voelker, R.A.; Greenleaf, A.L. Molecular cloning of sequences from a drosophila RNA polymerase ii locus by p element transposon tagging. Cell 1982, 31, 585-592.
    • (1982) Cell , vol.31 , pp. 585-592
    • Searles, L.L.1    Jokerst, R.S.2    Bingham, P.M.3    Voelker, R.A.4    Greenleaf, A.L.5
  • 106
    • 0019945644 scopus 로고
    • Genetic transformation of drosophila with transposable element vectors
    • Rubin, G.M.; Spradling, A.C. Genetic transformation of drosophila with transposable element vectors. Science 1982, 218, 348-353.
    • (1982) Science , vol.218 , pp. 348-353
    • Rubin, G.M.1    Spradling, A.C.2
  • 107
    • 0023848501 scopus 로고
    • Insertional mutagenesis of the drosophila genome with single P elements
    • Cooley, L.; Kelley, R.; Spradling, A. Insertional mutagenesis of the drosophila genome with single P elements. Science 1988, 239, 1121-1128.
    • (1988) Science , vol.239 , pp. 1121-1128
    • Cooley, L.1    Kelley, R.2    Spradling, A.3
  • 108
    • 0025264703 scopus 로고
    • Constructing deletions with defined endpoints in drosophila
    • Cooley, L.; Thompson, D.; Spradling, A.C. Constructing deletions with defined endpoints in drosophila. Proc. Natl. Acad. Sci. USA 1990, 87, 3170-3173.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 3170-3173
    • Cooley, L.1    Thompson, D.2    Spradling, A.C.3
  • 109
    • 0023488840 scopus 로고
    • Detection in situ of genomic regulatory elements in drosophila
    • O'Kane, C.J.; Gehring, W.J. Detection in situ of genomic regulatory elements in drosophila. Proc. Natl. Acad. Sci. USA 1987, 84, 9123-9127.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 9123-9127
    • O'Kane, C.J.1    Gehring, W.J.2
  • 112
    • 0011704558 scopus 로고
    • Molecular structure of a somatically unstable transposable element in drosophila
    • Jacobson, J.W.; Medhora, M.M.; Hartl, D.L. Molecular structure of a somatically unstable transposable element in drosophila. Proc. Natl. Acad. Sci. USA 1986, 83, 8684-8688.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 8684-8688
    • Jacobson, J.W.1    Medhora, M.M.2    Hartl, D.L.3
  • 113
    • 0026015008 scopus 로고
    • Introduction of the transposable element mariner into the germline of drosophila melanogaster
    • Garza, D.; Medhora, M.; Koga, A.; Hartl, D.L. Introduction of the transposable element mariner into the germline of drosophila melanogaster. Genetics 1991, 128, 303-310.
    • (1991) Genetics , vol.128 , pp. 303-310
    • Garza, D.1    Medhora, M.2    Koga, A.3    Hartl, D.L.4
  • 114
    • 0026410226 scopus 로고
    • Minos, a new transposable element from drosophila hydei, is a member of the tc1-like family of transposons
    • Franz, G.; Savakis, C. Minos, a new transposable element from drosophila hydei, is a member of the tc1-like family of transposons. Nucleic Acids Res. 1991, 19, 6646.
    • (1991) Nucleic Acids Res , vol.19 , pp. 6646
    • Franz, G.1    Savakis, C.2
  • 115
    • 0028809850 scopus 로고
    • Introduction of the transposable element minos into the germ line of drosophila melanogaster
    • Loukeris, T.G.; Arca, B.; Livadaras, I.; Dialektaki, G.; Savakis, C. Introduction of the transposable element minos into the germ line of drosophila melanogaster. Proc. Natl. Acad. Sci. USA 1995, 92, 9485-9489.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 9485-9489
    • Loukeris, T.G.1    Arca, B.2    Livadaras, I.3    Dialektaki, G.4    Savakis, C.5
  • 116
    • 0032560534 scopus 로고    scopus 로고
    • The lepidopteran transposon vector, piggybac, mediates germ-line transformation in the mediterranean fruit fly
    • Handler, A.M.; McCombs, S.D.; Fraser, M.J.; Saul, S.H. The lepidopteran transposon vector, piggybac, mediates germ-line transformation in the mediterranean fruit fly. Proc. Natl. Acad. Sci. USA 1998, 95, 7520-7525.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 7520-7525
    • Handler, A.M.1    McCombs, S.D.2    Fraser, M.J.3    Saul, S.H.4
  • 117
    • 0033229922 scopus 로고    scopus 로고
    • Germline transformation of drosophila melanogaster with the piggybac transposon vector
    • Handler, A.M.; Harrell, R.A., 2nd. Germline transformation of drosophila melanogaster with the piggybac transposon vector. Insect Mol. Biol. 1999, 8, 449-457.
    • (1999) Insect Mol. Biol , vol.8 , pp. 449-457
    • Handler, A.M.1    Harrell II, R.A.2
  • 118
    • 0020554565 scopus 로고
    • The effect of chromosomal position on the expression of the drosophila xanthine dehydrogenase gene
    • Spradling, A.C.; Rubin, G.M. The effect of chromosomal position on the expression of the drosophila xanthine dehydrogenase gene. Cell 1983, 34, 47-57.
    • (1983) Cell , vol.34 , pp. 47-57
    • Spradling, A.C.1    Rubin, G.M.2
  • 119
    • 0022351501 scopus 로고
    • Effects of genomic position on the expression of transduced copies of the white gene of drosophila
    • Levis, R.; Hazelrigg, T.; Rubin, G.M. Effects of genomic position on the expression of transduced copies of the white gene of drosophila. Science 1985, 229, 558-561.
    • (1985) Science , vol.229 , pp. 558-561
    • Levis, R.1    Hazelrigg, T.2    Rubin, G.M.3
  • 120
    • 0033535997 scopus 로고    scopus 로고
    • A novel mechanism for p element homing in drosophila
    • Taillebourg, E.; Dura, J.M. A novel mechanism for p element homing in drosophila. Proc. Natl. Acad. Sci. USA 1999, 96, 6856-6861.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 6856-6861
    • Taillebourg, E.1    Dura, J.M.2
  • 121
    • 84856021982 scopus 로고    scopus 로고
    • P-element homing is facilitated by engrailed polycomb-group response elements in drosophila melanogaster
    • Cheng, Y.; Kwon, D.Y.; Arai, A.L.; Mucci, D.; Kassis, J.A. P-element homing is facilitated by engrailed polycomb-group response elements in drosophila melanogaster. PLoS One 2012, 7, e30437.
    • (2012) PLoS One , vol.7
    • Cheng, Y.1    Kwon, D.Y.2    Arai, A.L.3    Mucci, D.4    Kassis, J.A.5
  • 122
    • 0032510752 scopus 로고    scopus 로고
    • In vitro site-specific integration of bacteriophage DNA catalyzed by a recombinase of the resolvase/invertase family
    • Thorpe, H.M.; Smith, M.C. In vitro site-specific integration of bacteriophage DNA catalyzed by a recombinase of the resolvase/invertase family. Proc. Natl. Acad. Sci. USA 1998, 95, 5505-5510.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 5505-5510
    • Thorpe, H.M.1    Smith, M.C.2
  • 123
    • 2442458847 scopus 로고    scopus 로고
    • Construction of transgenic drosophila by using the site-specific integrase from phage phic31
    • Groth, A.C.; Fish, M.; Nusse, R.; Calos, M.P. Construction of transgenic drosophila by using the site-specific integrase from phage phic31. Genetics 2004, 166, 1775-1782.
    • (2004) Genetics , vol.166 , pp. 1775-1782
    • Groth, A.C.1    Fish, M.2    Nusse, R.3    Calos, M.P.4
  • 124
    • 33845698104 scopus 로고    scopus 로고
    • P[acman]: A bac transgenic platform for targeted insertion of large DNA fragments in d. Melanogaster
    • Venken, K.J.; He, Y.; Hoskins, R.A.; Bellen, H.J. P[acman]: A bac transgenic platform for targeted insertion of large DNA fragments in d. Melanogaster. Science 2006, 314, 1747-1751.
    • (2006) Science , vol.314 , pp. 1747-1751
    • Venken, K.J.1    He, Y.2    Hoskins, R.A.3    Bellen, H.J.4
  • 125
    • 33847660443 scopus 로고    scopus 로고
    • An optimized transgenesis system for drosophila using germ-line-specific phic31 integrases
    • Bischof, J.; Maeda, R.K.; Hediger, M.; Karch, F.; Basler, K. An optimized transgenesis system for drosophila using germ-line-specific phic31 integrases. Proc. Natl. Acad. Sci. USA 2007, 104, 3312-3317.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 3312-3317
    • Bischof, J.1    Maeda, R.K.2    Hediger, M.3    Karch, F.4    Basler, K.5
  • 126
    • 41349092785 scopus 로고    scopus 로고
    • Exploiting position effects and the gypsy retrovirus insulator to engineer precisely expressed transgenes
    • Markstein, M.; Pitsouli, C.; Villalta, C.; Celniker, S.E.; Perrimon, N. Exploiting position effects and the gypsy retrovirus insulator to engineer precisely expressed transgenes. Nat. Genet. 2008, 40, 476-483.
    • (2008) Nat. Genet , vol.40 , pp. 476-483
    • Markstein, M.1    Pitsouli, C.2    Villalta, C.3    Celniker, S.E.4    Perrimon, N.5
  • 127
    • 0027160708 scopus 로고
    • Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
    • Brand, A.H.; Perrimon, N. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 1993, 118, 401-415.
    • (1993) Development , vol.118 , pp. 401-415
    • Brand, A.H.1    Perrimon, N.2
  • 130
    • 0037295418 scopus 로고    scopus 로고
    • Piggybac-based insertional mutagenesis and enhancer detection as a tool for functional insect genomics
    • Horn, C.; Offen, N.; Nystedt, S.; Hacker, U.; Wimmer, E.A. Piggybac-based insertional mutagenesis and enhancer detection as a tool for functional insect genomics. Genetics 2003, 163, 647-661.
    • (2003) Genetics , vol.163 , pp. 647-661
    • Horn, C.1    Offen, N.2    Nystedt, S.3    Hacker, U.4    Wimmer, E.A.5
  • 133
    • 4444277115 scopus 로고    scopus 로고
    • Refining gal4-driven transgene expression in drosophila with a gal80 enhancer-trap
    • Suster, M.L.; Seugnet, L.; Bate, M.; Sokolowski, M.B. Refining gal4-driven transgene expression in drosophila with a gal80 enhancer-trap. Genesis 2004, 39, 240-245.
    • (2004) Genesis , vol.39 , pp. 240-245
    • Suster, M.L.1    Seugnet, L.2    Bate, M.3    Sokolowski, M.B.4
  • 134
    • 0345168202 scopus 로고    scopus 로고
    • Spatiotemporal rescue of memory dysfunction in drosophila
    • McGuire, S.E.; Le, P.T.; Osborn, A.J.; Matsumoto, K.; Davis, R.L. Spatiotemporal rescue of memory dysfunction in drosophila. Science 2003, 302, 1765-1768.
    • (2003) Science , vol.302 , pp. 1765-1768
    • McGuire, S.E.1    Le, P.T.2    Osborn, A.J.3    Matsumoto, K.4    Davis, R.L.5
  • 135
    • 0033103536 scopus 로고    scopus 로고
    • Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis
    • Lee, T.; Luo, L. Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis. Neuron 1999, 22, 451-461.
    • (1999) Neuron , vol.22 , pp. 451-461
    • Lee, T.1    Luo, L.2
  • 136
    • 0033983237 scopus 로고    scopus 로고
    • Investigating the function of follicular subpopulations during drosophila oogenesis through hormone-dependent enhancer-targeted cell ablation
    • Han, D.D.; Stein, D.; Stevens, L.M. Investigating the function of follicular subpopulations during drosophila oogenesis through hormone-dependent enhancer-targeted cell ablation. Development 2000, 127, 573-583.
    • (2000) Development , vol.127 , pp. 573-583
    • Han, D.D.1    Stein, D.2    Stevens, L.M.3
  • 137
    • 0035940416 scopus 로고    scopus 로고
    • A conditional tissue-specific transgene expression system using inducible gal4
    • Osterwalder, T.; Yoon, K.S.; White, B.H.; Keshishian, H. A conditional tissue-specific transgene expression system using inducible gal4. Proc. Natl. Acad. Sci. USA 2001, 98, 12596-12601.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 12596-12601
    • Osterwalder, T.1    Yoon, K.S.2    White, B.H.3    Keshishian, H.4
  • 138
    • 0035940413 scopus 로고    scopus 로고
    • P[switch], a system for spatial and temporal control of gene expression in drosophila melanogaster
    • Roman, G.; Endo, K.; Zong, L.; Davis, R.L. P[switch], a system for spatial and temporal control of gene expression in drosophila melanogaster. Proc. Natl. Acad. Sci. USA 2001, 98, 12602-12607.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 12602-12607
    • Roman, G.1    Endo, K.2    Zong, L.3    Davis, R.L.4
  • 140
    • 33745742246 scopus 로고    scopus 로고
    • Genetic mosaic with dual binary transcriptional systems in drosophila
    • Lai, S.L.; Lee, T. Genetic mosaic with dual binary transcriptional systems in drosophila. Nat. Neurosci. 2006, 9, 703-709.
    • (2006) Nat. Neurosci , vol.9 , pp. 703-709
    • Lai, S.L.1    Lee, T.2
  • 141
    • 77951925182 scopus 로고    scopus 로고
    • The q system: A repressible binary system for transgene expression, lineage tracing, and mosaic analysis
    • Potter, C.J.; Tasic, B.; Russler, E.V.; Liang, L.; Luo, L. The q system: A repressible binary system for transgene expression, lineage tracing, and mosaic analysis. Cell 2010, 141, 536-548.
    • (2010) Cell , vol.141 , pp. 536-548
    • Potter, C.J.1    Tasic, B.2    Russler, E.V.3    Liang, L.4    Luo, L.5
  • 142
    • 77957984712 scopus 로고    scopus 로고
    • Refined lexa transactivators and their use in combination with the drosophila gal4 system
    • Yagi, R.; Mayer, F.; Basler, K. Refined lexa transactivators and their use in combination with the drosophila gal4 system. Proc. Natl. Acad. Sci. USA 2010, 107, 16166-16171.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 16166-16171
    • Yagi, R.1    Mayer, F.2    Basler, K.3
  • 143
    • 0027081864 scopus 로고
    • Use of a yeast site-specific recombinase to generate embryonic mosaics in drosophila
    • Dang, D.T.; Perrimon, N. Use of a yeast site-specific recombinase to generate embryonic mosaics in drosophila. Dev. Genet. 1992, 13, 367-375.
    • (1992) Dev. Genet , vol.13 , pp. 367-375
    • Dang, D.T.1    Perrimon, N.2
  • 144
    • 0001347357 scopus 로고
    • Simple and efficient generation of marked clones in drosophila
    • Harrison, D.A.; Perrimon, N. Simple and efficient generation of marked clones in drosophila. Curr. Biol. 1993, 3, 424-433.
    • (1993) Curr. Biol , vol.3 , pp. 424-433
    • Harrison, D.A.1    Perrimon, N.2
  • 145
    • 0025907542 scopus 로고
    • Site-specific recombination between homologous chromosomes in drosophila
    • Golic, K.G. Site-specific recombination between homologous chromosomes in drosophila. Science 1991, 252, 958-961.
    • (1991) Science , vol.252 , pp. 958-961
    • Golic, K.G.1
  • 146
    • 67649813443 scopus 로고    scopus 로고
    • Twin-spot marcm to reveal the developmental origin and identity of neurons
    • Yu, H.H.; Chen, C.H.; Shi, L.; Huang, Y.; Lee, T. Twin-spot marcm to reveal the developmental origin and identity of neurons. Nat. Neurosci. 2009, 12, 947-953.
    • (2009) Nat. Neurosci , vol.12 , pp. 947-953
    • Yu, H.H.1    Chen, C.H.2    Shi, L.3    Huang, Y.4    Lee, T.5
  • 148
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in caenorhabditis elegans
    • Fire, A.; Xu, S.; Montgomery, M.K.; Kostas, S.A.; Driver, S.E.; Mello, C.C. Potent and specific genetic interference by double-stranded RNA in caenorhabditis elegans. Nature 1998, 391, 806-811.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 149
    • 0037062951 scopus 로고    scopus 로고
    • RNA interference
    • Hannon, G.J. RNA interference. Nature 2002, 418, 244-251.
    • (2002) Nature , vol.418 , pp. 244-251
    • Hannon, G.J.1
  • 150
    • 0032443021 scopus 로고    scopus 로고
    • Use of dsrna-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway
    • Kennerdell, J.R.; Carthew, R.W. Use of dsrna-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway. Cell 1998, 95, 1017-1026.
    • (1998) Cell , vol.95 , pp. 1017-1026
    • Kennerdell, J.R.1    Carthew, R.W.2
  • 151
    • 0033573924 scopus 로고    scopus 로고
    • Targeted disruption of gene function in drosophila by RNA interference (RNA-i): A role for nautilus in embryonic somatic muscle formation
    • Misquitta, L.; Paterson, B.M. Targeted disruption of gene function in drosophila by RNA interference (RNA-i): A role for nautilus in embryonic somatic muscle formation. Proc. Natl. Acad. Sci. USA 1999, 96, 1451-1456.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 1451-1456
    • Misquitta, L.1    Paterson, B.M.2
  • 152
    • 0034673638 scopus 로고    scopus 로고
    • An RNA-directed nuclease mediates post-transcriptional gene silencing in drosophila cells
    • Hammond, S.M.; Bernstein, E.; Beach, D.; Hannon, G.J. An RNA-directed nuclease mediates post-transcriptional gene silencing in drosophila cells. Nature 2000, 404, 293-296.
    • (2000) Nature , vol.404 , pp. 293-296
    • Hammond, S.M.1    Bernstein, E.2    Beach, D.3    Hannon, G.J.4
  • 153
    • 0033883114 scopus 로고    scopus 로고
    • Heritable gene silencing in drosophila using double-stranded RNA
    • Kennerdell, J.R.; Carthew, R.W. Heritable gene silencing in drosophila using double-stranded RNA. Nat. Biotechnol. 2000, 18, 896-898.
    • (2000) Nat. Biotechnol , vol.18 , pp. 896-898
    • Kennerdell, J.R.1    Carthew, R.W.2
  • 155
    • 0242361514 scopus 로고    scopus 로고
    • A functional genomic analysis of cell morphology using RNA interference
    • doi:10.1186/1475-4924-2-27
    • Kiger, A.A.; Baum, B.; Jones, S.; Jones, M.R.; Coulson, A.; Echeverri, C.; Perrimon, N. A functional genomic analysis of cell morphology using RNA interference. J. Biol. 2003, doi:10.1186/1475-4924-2-27.
    • (2003) J. Biol
    • Kiger, A.A.1    Baum, B.2    Jones, S.3    Jones, M.R.4    Coulson, A.5    Echeverri, C.6    Perrimon, N.7
  • 156
    • 0037470952 scopus 로고    scopus 로고
    • Identification of hedgehog pathway components by RNAi in drosophila cultured cells
    • Lum, L.; Yao, S.; Mozer, B.; Rovescalli, A.; von Kessler, D.; Nirenberg, M.; Beachy, P.A. Identification of hedgehog pathway components by RNAi in drosophila cultured cells. Science 2003, 299, 2039-2045.
    • (2003) Science , vol.299 , pp. 2039-2045
    • Lum, L.1    Yao, S.2    Mozer, B.3    Rovescalli, A.4    von Kessler, D.5    Nirenberg, M.6    Beachy, P.A.7
  • 158
    • 19344370696 scopus 로고    scopus 로고
    • Functional dissection of an innate immune response by a genome-wide RNAi screen
    • Foley, E.; O'Farrell, P.H. Functional dissection of an innate immune response by a genome-wide RNAi screen. PLoS Biol. 2004, 2, E203.
    • (2004) PLoS Biol , vol.2
    • Foley, E.1    O'Farrell, P.H.2
  • 160
    • 84902264153 scopus 로고    scopus 로고
    • Available online, accessed on 13 January 2014
    • Ueda, R. RNAi Fly-A Comprehensive RNAi-Mutant Fly Bank. Available online: http://www.shigen.nig.ac.jp/fly/nigfly/about/aboutrnai.jsp/ (accessed on 13 January 2014).
    • RNAi Fly-A Comprehensive RNAi-Mutant Fly Bank
    • Ueda, R.1
  • 163
  • 165
    • 78149472321 scopus 로고    scopus 로고
    • A genome-wide drosophila screen for heat nociception identifies alpha2delta3 as an evolutionarily conserved pain gene
    • Neely, G.G.; Hess, A.; Costigan, M.; Keene, A.C.; Goulas, S.; Langeslag, M.; Griffin, R.S.; Belfer, I.; Dai, F.; Smith, S.B., et al. A genome-wide drosophila screen for heat nociception identifies alpha2delta3 as an evolutionarily conserved pain gene. Cell 2010, 143, 628-638.
    • (2010) Cell , vol.143 , pp. 628-638
    • Neely, G.G.1    Hess, A.2    Costigan, M.3    Keene, A.C.4    Goulas, S.5    Langeslag, M.6    Griffin, R.S.7    Belfer, I.8    Dai, F.9    Smith, S.B.10
  • 167
    • 84878851966 scopus 로고    scopus 로고
    • A transcriptome-wide RNAi screen in the drosophila ovary reveals factors of the germline piRNA pathway
    • Czech, B.; Preall, J.B.; McGinn, J.; Hannon, G.J. A transcriptome-wide RNAi screen in the drosophila ovary reveals factors of the germline piRNA pathway. Mol. Cell 2013, 50, 749-761.
    • (2013) Mol. Cell , vol.50 , pp. 749-761
    • Czech, B.1    Preall, J.B.2    McGinn, J.3    Hannon, G.J.4
  • 168
    • 72449143602 scopus 로고    scopus 로고
    • Cross-species RNAi rescue platform in drosophila melanogaster
    • Kondo, S.; Booker, M.; Perrimon, N. Cross-species RNAi rescue platform in drosophila melanogaster. Genetics 2009, 183, 1165-1173.
    • (2009) Genetics , vol.183 , pp. 1165-1173
    • Kondo, S.1    Booker, M.2    Perrimon, N.3
  • 169
    • 77749245950 scopus 로고    scopus 로고
    • In vivo RNAi rescue in drosophila melanogaster with genomic transgenes from drosophila pseudoobscura
    • Langer, C.C.H.; Ejsmont, R.K.; Schönbauer, C.; Schnorrer, F.; Tomancak, P. In vivo RNAi rescue in drosophila melanogaster with genomic transgenes from drosophila pseudoobscura. PLoS One 2010, 5, e8928.
    • (2010) PLoS One , vol.5
    • Langer, C.C.H.1    Ejsmont, R.K.2    Schönbauer, C.3    Schnorrer, F.4    Tomancak, P.5
  • 170
    • 67949104969 scopus 로고    scopus 로고
    • A novel method for tissue-specific RNAi rescue in drosophila
    • Schulz, J.G.; David, G.; Hassan, B.A. A novel method for tissue-specific RNAi rescue in drosophila. Nucleic Acids Res. 2009, 37, e93.
    • (2009) Nucleic Acids Res , vol.37
    • Schulz, J.G.1    David, G.2    Hassan, B.A.3
  • 171
    • 0029558480 scopus 로고
    • Segmental patterning of heart precursors in drosophila
    • Lawrence, P.A.; Bodmer, R.; Vincent, J.P. Segmental patterning of heart precursors in drosophila. Development 1995, 121, 4303-4308.
    • (1995) Development , vol.121 , pp. 4303-4308
    • Lawrence, P.A.1    Bodmer, R.2    Vincent, J.P.3
  • 172
    • 0031795344 scopus 로고    scopus 로고
    • In vivo dynamics of axon pathfinding in the drosophilia CNS: A time-lapse study of an identified motorneuron
    • Murray, M.J.; Merritt, D.J.; Brand, A.H.; Whitington, P.M. In vivo dynamics of axon pathfinding in the drosophilia CNS: A time-lapse study of an identified motorneuron. J. Neurobiol. 1998, 37, 607-621.
    • (1998) J. Neurobiol , vol.37 , pp. 607-621
    • Murray, M.J.1    Merritt, D.J.2    Brand, A.H.3    Whitington, P.M.4
  • 173
    • 0031924072 scopus 로고    scopus 로고
    • Use of bacteriophage lambda recombination functions to promote gene replacement in escherichia coli
    • Murphy, K.C. Use of bacteriophage lambda recombination functions to promote gene replacement in escherichia coli. J. Bacteriol. 1998, 180, 2063-2071.
    • (1998) J. Bacteriol , vol.180 , pp. 2063-2071
    • Murphy, K.C.1
  • 174
    • 0031664853 scopus 로고    scopus 로고
    • A new logic for DNA engineering using recombination in escherichia coli
    • Zhang, Y.; Buchholz, F.; Muyrers, J.P.; Stewart, A.F. A new logic for DNA engineering using recombination in escherichia coli. Nat. Genet. 1998, 20, 123-128.
    • (1998) Nat. Genet , vol.20 , pp. 123-128
    • Zhang, Y.1    Buchholz, F.2    Muyrers, J.P.3    Stewart, A.F.4
  • 175
    • 0033559118 scopus 로고    scopus 로고
    • Rapid modification of bacterial artificial chromosomes by et-recombination
    • Muyrers, J.P.; Zhang, Y.; Testa, G.; Stewart, A.F. Rapid modification of bacterial artificial chromosomes by et-recombination. Nucleic Acids Res. 1999, 27, 1555-1557.
    • (1999) Nucleic Acids Res , vol.27 , pp. 1555-1557
    • Muyrers, J.P.1    Zhang, Y.2    Testa, G.3    Stewart, A.F.4
  • 178
    • 67349226099 scopus 로고    scopus 로고
    • A toolkit for high-throughput, cross-species gene engineering in drosophila
    • Ejsmont, R.K.; Sarov, M.; Winkler, S.; Lipinski, K.A.; Tomancak, P. A toolkit for high-throughput, cross-species gene engineering in drosophila. Nat. Methods 2009, 6, 435-437.
    • (2009) Nat. Methods , vol.6 , pp. 435-437
    • Ejsmont, R.K.1    Sarov, M.2    Winkler, S.3    Lipinski, K.A.4    Tomancak, P.5
  • 179
    • 0033646073 scopus 로고    scopus 로고
    • Highly sensitive, fluorescent transformation marker for drosophila transgenesis
    • Horn, C.; Jaunich, B.; Wimmer, E.A. Highly sensitive, fluorescent transformation marker for drosophila transgenesis. Dev. Genes Evol. 2000, 210, 623-629.
    • (2000) Dev. Genes Evol , vol.210 , pp. 623-629
    • Horn, C.1    Jaunich, B.2    Wimmer, E.A.3
  • 181
    • 84988044061 scopus 로고    scopus 로고
    • A protocol for mosaic analysis with a repressible cell marker (Marcm) in drosophila
    • Wu, J.S.; Luo, L. A protocol for mosaic analysis with a repressible cell marker (Marcm) in drosophila. Nat. Protoc. 2006, 1, 2583-2589.
    • (2006) Nat. Protoc , vol.1 , pp. 2583-2589
    • Wu, J.S.1    Luo, L.2
  • 182
    • 0034674713 scopus 로고    scopus 로고
    • Gene targeting by homologous recombination in drosophila
    • Rong, Y.S.; Golic, K.G. Gene targeting by homologous recombination in drosophila. Science 2000, 288, 2013-2018.
    • (2000) Science , vol.288 , pp. 2013-2018
    • Rong, Y.S.1    Golic, K.G.2
  • 183
    • 0037418177 scopus 로고    scopus 로고
    • Ends-out, or replacement, gene targeting in drosophila
    • Gong, W.J.; Golic, K.G. Ends-out, or replacement, gene targeting in drosophila. Proc. Natl. Acad. Sci. USA 2003, 100, 2556-2561.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 2556-2561
    • Gong, W.J.1    Golic, K.G.2
  • 185
    • 66249144461 scopus 로고    scopus 로고
    • From the cover: Directed, efficient, and versatile modifications of the drosophila genome by genomic engineering
    • Huang, J.; Zhou, W.; Dong, W.; Watson, A.M.; Hong, Y. From the cover: Directed, efficient, and versatile modifications of the drosophila genome by genomic engineering. Proc. Natl. Acad. Sci. USA 2009, 106, 8284-8289.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 8284-8289
    • Huang, J.1    Zhou, W.2    Dong, W.3    Watson, A.M.4    Hong, Y.5
  • 186
  • 187
    • 0030032063 scopus 로고    scopus 로고
    • Hybrid restriction enzymes: Zinc finger fusions to Fok I cleavage domain
    • Kim, Y.G.; Cha, J.; Chandrasegaran, S. Hybrid restriction enzymes: Zinc finger fusions to Fok I cleavage domain. Proc. Natl. Acad. Sci. USA 1996, 93, 1156-1160.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 1156-1160
    • Kim, Y.G.1    Cha, J.2    Chandrasegaran, S.3
  • 188
    • 0036021389 scopus 로고    scopus 로고
    • Targeted chromosomal cleavage and mutagenesis in drosophila using zinc-finger nucleases
    • Bibikova, M.; Golic, M.; Golic, K.G.; Carroll, D. Targeted chromosomal cleavage and mutagenesis in drosophila using zinc-finger nucleases. Genetics 2002, 161, 1169-1175.
    • (2002) Genetics , vol.161 , pp. 1169-1175
    • Bibikova, M.1    Golic, M.2    Golic, K.G.3    Carroll, D.4
  • 189
    • 84891722219 scopus 로고    scopus 로고
    • Highly efficient crispr/cas9-mediated knock-in in zebrafish by homology-independent DNA repair
    • Auer, T.O.; Duroure, K.; de Cian, A.; Concordet, J.P.; Del Bene, F. Highly efficient crispr/cas9-mediated knock-in in zebrafish by homology-independent DNA repair. Genome Res. 2014, 24, 142-153.
    • (2014) Genome Res , vol.24 , pp. 142-153
    • Auer, T.O.1    Duroure, K.2    de Cian, A.3    Concordet, J.P.4    Del Bene, F.5
  • 190
  • 193
    • 78650855391 scopus 로고    scopus 로고
    • Preassembled zinc-finger arrays for rapid construction of zfns
    • doi:10.1038/nmeth0111-7a
    • Kim, S.; Lee, M.J.; Kim, H.; Kang, M.; Kim, J.S. Preassembled zinc-finger arrays for rapid construction of zfns. Nat. Methods 2011, doi:10.1038/nmeth0111-7a.
    • (2011) Nat. Methods
    • Kim, S.1    Lee, M.J.2    Kim, H.3    Kang, M.4    Kim, J.S.5
  • 195
    • 79952302385 scopus 로고    scopus 로고
    • De novo-engineered transcription activator-like effector (tale) hybrid nuclease with novel DNA binding specificity creates double-strand breaks
    • Mahfouz, M.M.; Li, L.; Shamimuzzaman, M.; Wibowo, A.; Fang, X.; Zhu, J.K. De novo-engineered transcription activator-like effector (tale) hybrid nuclease with novel DNA binding specificity creates double-strand breaks. Proc. Natl. Acad. Sci. USA 2011, 108, 2623-2628.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 2623-2628
    • Mahfouz, M.M.1    Li, L.2    Shamimuzzaman, M.3    Wibowo, A.4    Fang, X.5    Zhu, J.K.6
  • 197
    • 79960066049 scopus 로고    scopus 로고
    • Assembly of custom tale-type DNA binding domains by modular cloning
    • Morbitzer, R.; Elsaesser, J.; Hausner, J.; Lahaye, T. Assembly of custom tale-type DNA binding domains by modular cloning. Nucleic Acids Res. 2011, 39, 5790-5799.
    • (2011) Nucleic Acids Res , vol.39 , pp. 5790-5799
    • Morbitzer, R.1    Elsaesser, J.2    Hausner, J.3    Lahaye, T.4
  • 198
    • 72149090954 scopus 로고    scopus 로고
    • A simple cipher governs DNA recognition by tal effectors
    • doi:10.1126/science.1178817
    • Moscou, M.J.; Bogdanove, A.J. A simple cipher governs DNA recognition by tal effectors. Science 2009, doi:10.1126/science.1178817.
    • (2009) Science
    • Moscou, M.J.1    Bogdanove, A.J.2
  • 200
    • 84866859751 scopus 로고    scopus 로고
    • Cas9-crrna ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria
    • Gasiunas, G.; Barrangou, R.; Horvath, P.; Siksnys, V. Cas9-crrna ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria. Proc. Natl. Acad. Sci. USA 2012, 109, E2579-E2586.
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109
    • Gasiunas, G.1    Barrangou, R.2    Horvath, P.3    Siksnys, V.4
  • 201
    • 84865070369 scopus 로고    scopus 로고
    • A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity
    • Jinek, M.; Chylinski, K.; Fonfara, I.; Hauer, M.; Doudna, J.A.; Charpentier, E. A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science 2012, 337, 816-821.
    • (2012) Science , vol.337 , pp. 816-821
    • Jinek, M.1    Chylinski, K.2    Fonfara, I.3    Hauer, M.4    Doudna, J.A.5    Charpentier, E.6
  • 202
    • 84892437994 scopus 로고    scopus 로고
    • Highly efficient targeted mutagenesis of drosophila with the crispr/cas9 system
    • Bassett, A.R.; Tibbit, C.; Ponting, C.P.; Liu, J.L. Highly efficient targeted mutagenesis of drosophila with the crispr/cas9 system. Cell Rep. 2013, 4, 220-228.
    • (2013) Cell Rep , vol.4 , pp. 220-228
    • Bassett, A.R.1    Tibbit, C.2    Ponting, C.P.3    Liu, J.L.4
  • 204
    • 84883809403 scopus 로고    scopus 로고
    • Highly efficient genome modifications mediated by crispr/cas9 in drosophila
    • Yu, Z.; Ren, M.; Wang, Z.; Zhang, B.; Rong, Y.S.; Jiao, R.; Gao, G. Highly efficient genome modifications mediated by crispr/cas9 in drosophila. Genetics 2013, 195, 289-291.
    • (2013) Genetics , vol.195 , pp. 289-291
    • Yu, Z.1    Ren, M.2    Wang, Z.3    Zhang, B.4    Rong, Y.S.5    Jiao, R.6    Gao, G.7
  • 205
    • 84888372954 scopus 로고    scopus 로고
    • A simplified and efficient germline-specific crispr/cas9 system for drosophila genomic engineering
    • Sebo, Z.L.; Lee, H.B.; Peng, Y.; Guo, Y. A simplified and efficient germline-specific crispr/cas9 system for drosophila genomic engineering. Fly 2014, 8, 52-57.
    • (2014) Fly , vol.8 , pp. 52-57
    • Sebo, Z.L.1    Lee, H.B.2    Peng, Y.3    Guo, Y.4
  • 208
    • 84884925278 scopus 로고    scopus 로고
    • Highly improved gene targeting by germline-specific cas9 expression in drosophila
    • Kondo, S.; Ueda, R. Highly improved gene targeting by germline-specific cas9 expression in drosophila. Genetics 2013, 195, 715-721.
    • (2013) Genetics , vol.195 , pp. 715-721
    • Kondo, S.1    Ueda, R.2
  • 209
    • 84887902944 scopus 로고    scopus 로고
    • Accelerated homologous recombination and subsequent genome modification in drosophila
    • Baena-Lopez, L.A.; Alexandre, C.; Mitchell, A.; Pasakarnis, L.; Vincent, J.P. Accelerated homologous recombination and subsequent genome modification in drosophila. Development 2013, 140, 4818-4825.
    • (2013) Development , vol.140 , pp. 4818-4825
    • Baena-Lopez, L.A.1    Alexandre, C.2    Mitchell, A.3    Pasakarnis, L.4    Vincent, J.P.5
  • 210
    • 84856422956 scopus 로고    scopus 로고
    • Power tools for gene expression and clonal analysis in drosophila
    • Del Valle Rodriguez, A.; Didiano, D.; Desplan, C. Power tools for gene expression and clonal analysis in drosophila. Nat. Methods 2012, 9, 47-55.
    • (2012) Nat. Methods , vol.9 , pp. 47-55
    • Del Valle Rodriguez, A.1    Didiano, D.2    Desplan, C.3
  • 211
    • 84860137072 scopus 로고    scopus 로고
    • Genome-wide manipulations of drosophila melanogaster with transposons, flp recombinase, and phic31 integrase
    • Venken, K.J.; Bellen, H.J. Genome-wide manipulations of drosophila melanogaster with transposons, flp recombinase, and phic31 integrase. Methods Mol. Biol. 2012, 859, 203-228.
    • (2012) Methods Mol. Biol , vol.859 , pp. 203-228
    • Venken, K.J.1    Bellen, H.J.2
  • 212
    • 84887478758 scopus 로고    scopus 로고
    • Crispr/cas9-mediated genome engineering and the promise of designer flies on demand
    • doi:10.4161/fly.26566
    • Gratz, S.J.; Wildonger, J.; Harrison, M.M.; O'Connor-Giles, K.M. Crispr/cas9-mediated genome engineering and the promise of designer flies on demand. Fly 2013, doi:10.4161/fly.26566.
    • (2013) Fly
    • Gratz, S.J.1    Wildonger, J.2    Harrison, M.M.3    O'Connor-Giles, K.M.4
  • 213
    • 0034837386 scopus 로고    scopus 로고
    • A systematic analysis of human disease-associated gene sequences in drosophila melanogaster
    • Reiter, L.T.; Potocki, L.; Chien, S.; Gribskov, M.; Bier, E. A systematic analysis of human disease-associated gene sequences in drosophila melanogaster. Genome Res. 2001, 11, 1114-1125.
    • (2001) Genome Res , vol.11 , pp. 1114-1125
    • Reiter, L.T.1    Potocki, L.2    Chien, S.3    Gribskov, M.4    Bier, E.5
  • 214
    • 0036081081 scopus 로고    scopus 로고
    • Homophila: Human disease gene cognates in drosophila
    • Chien, S.; Reiter, L.T.; Bier, E.; Gribskov, M. Homophila: Human disease gene cognates in drosophila. Nucleic Acids Res. 2002, 30, 149-151.
    • (2002) Nucleic Acids Res , vol.30 , pp. 149-151
    • Chien, S.1    Reiter, L.T.2    Bier, E.3    Gribskov, M.4
  • 215
    • 84874596928 scopus 로고    scopus 로고
    • Designer tales team up for highly efficient gene induction
    • Richter, A.; Boch, J. Designer tales team up for highly efficient gene induction. Nat. Methods 2013, 10, 207-208.
    • (2013) Nat. Methods , vol.10 , pp. 207-208
    • Richter, A.1    Boch, J.2
  • 216
    • 84881449454 scopus 로고    scopus 로고
    • Tale-mediated modulation of transcriptional enhancers in vivo
    • Crocker, J.; Stern, D.L. Tale-mediated modulation of transcriptional enhancers in vivo. Nat. Methods 2013, 10, 762-767.
    • (2013) Nat. Methods , vol.10 , pp. 762-767
    • Crocker, J.1    Stern, D.L.2
  • 217
    • 84884856342 scopus 로고    scopus 로고
    • Cas9 as a versatile tool for engineering biology
    • Mali, P.; Esvelt, K.M.; Church, G.M. Cas9 as a versatile tool for engineering biology. Nat. Methods 2013, 10, 957-963.
    • (2013) Nat. Methods , vol.10 , pp. 957-963
    • Mali, P.1    Esvelt, K.M.2    Church, G.M.3
  • 218
    • 84902271528 scopus 로고    scopus 로고
    • modENCODE Consortium Modencode Comparative Genomics Whitepaper. Available online: http://www.genome.gov/Pages/Research/Sequencing/SeqProposals/modENCODE_ComparativeGenomics_WhitePaper.pdf (accessed on 16 January 2014).


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